메뉴 건너뛰기




Volumn 34, Issue 1, 1999, Pages 42-48

Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat

Author keywords

[No Author keywords available]

Indexed keywords

DIALLYL DISULFIDE; GLUTATHIONE TRANSFERASE; ORGANOSULFUR DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

EID: 0032838660     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC340106     Document Type: Article
Times cited : (76)

References (57)
  • 3
    • 0031410830 scopus 로고    scopus 로고
    • Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats
    • Tanaka, T, Kawabata, K, Kakumoto, M, Makita, H, Hara, A, et al.: Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats. Carcinogenesis 18, 2155-2161, 1997.
    • (1997) Carcinogenesis , vol.18 , pp. 2155-2161
    • Tanaka, T.1    Kawabata, K.2    Kakumoto, M.3    Makita, H.4    Hara, A.5
  • 4
    • 0027215563 scopus 로고
    • Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea
    • Katiyar, SK, Agarwal, R, Zaim, MT, and Mukhtar, H: Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea. Carcinogenesis 14, 849-855, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 849-855
    • Katiyar, S.K.1    Agarwal, R.2    Zaim, M.T.3    Mukhtar, H.4
  • 5
    • 0030931522 scopus 로고    scopus 로고
    • Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
    • Fahey, JW, Zhang, Y, and Talalay, P: Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA 94, 10367-10372, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10367-10372
    • Fahey, J.W.1    Zhang, Y.2    Talalay, P.3
  • 6
    • 0020076847 scopus 로고
    • Glutathione S-transferase activity: Enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents
    • Sparnins, VL, Venegas, PL, and Wattenberg, LW: Glutathione S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents. JNCI 68, 493-496, 1982.
    • (1982) JNCI , vol.68 , pp. 493-496
    • Sparnins, V.L.1    Venegas, P.L.2    Wattenberg, L.W.3
  • 8
    • 0002117840 scopus 로고
    • DT diaphorase: A historical review
    • Ernster, L: DT diaphorase: a historical review. Chem Script 27A, 1-13, 1987.
    • (1987) Chem Script , vol.27 A , pp. 1-13
    • Ernster, L.1
  • 9
    • 0002013623 scopus 로고
    • Induction of DT diaphorase and functionally related enzymes by anti-carcinogenic and anti-toxic compounds
    • Benson, AM: Induction of DT diaphorase and functionally related enzymes by anti-carcinogenic and anti-toxic compounds. Chem Script 27A, 67-69, 1987.
    • (1987) Chem Script , vol.27 A , pp. 67-69
    • Benson, A.M.1
  • 10
    • 0024781837 scopus 로고
    • Mechanisms of induction of enzymes that protect against chemical carcinogenesis
    • Talalay, P: Mechanisms of induction of enzymes that protect against chemical carcinogenesis. Adv Enzyme Regul 28, 237-250, 1989.
    • (1989) Adv Enzyme Regul , vol.28 , pp. 237-250
    • Talalay, P.1
  • 11
    • 0028825881 scopus 로고
    • Identification of a class 3 aldehyde dehydrogenase in human saliva and increased levels of this enzyme, glutathione S-transferases, and DT-diaphorase in the saliva of subjects who continually ingest large quantities of coffee or broccoli
    • Sreerama, L, Hedge, MW, and Sladek, NE: Identification of a class 3 aldehyde dehydrogenase in human saliva and increased levels of this enzyme, glutathione S-transferases, and DT-diaphorase in the saliva of subjects who continually ingest large quantities of coffee or broccoli. Clin Cancer Res 1, 1153-1163, 1995.
    • (1995) Clin Cancer Res , vol.1 , pp. 1153-1163
    • Sreerama, L.1    Hedge, M.W.2    Sladek, N.E.3
  • 13
    • 0030868098 scopus 로고    scopus 로고
    • Chemoprevention by inducers of carcinogen detoxication enzymes
    • Kensler, TW: Chemoprevention by inducers of carcinogen detoxication enzymes. Environ Health Perspect 105 Suppl 4, 965-970, 1997.
    • (1997) Environ Health Perspect , vol.105 , Issue.SUPPL. 4 , pp. 965-970
    • Kensler, T.W.1
  • 14
    • 0030875366 scopus 로고    scopus 로고
    • An overview of chemoprevention: Current status and future prospects
    • Wattenberg, LW: An overview of chemoprevention: current status and future prospects. Proc Soc Exp Biol Med 216, 133-141, 1997.
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 133-141
    • Wattenberg, L.W.1
  • 15
    • 0031308138 scopus 로고    scopus 로고
    • Induction of DT-diaphorase in cancer chemoprevention and chemotherapy
    • Begleiter, A, Leith, MK, Curphey, TJ, and Doherty, GP: Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. Oncol Res 9, 371-382, 1997.
    • (1997) Oncol Res , vol.9 , pp. 371-382
    • Begleiter, A.1    Leith, M.K.2    Curphey, T.J.3    Doherty, G.P.4
  • 16
    • 0002614390 scopus 로고    scopus 로고
    • Can Allium vegetables prevent cancer?
    • Ernst, E: Can Allium vegetables prevent cancer? Phytomedicine 4, 79-83, 1997.
    • (1997) Phytomedicine , vol.4 , pp. 79-83
    • Ernst, E.1
  • 18
    • 0025331836 scopus 로고
    • Garlic: A review of its relationship to malignant disease
    • Dausch, JG, and Nixon, DW: Garlic: a review of its relationship to malignant disease. Prev Med 19, 346-361, 1990.
    • (1990) Prev Med , vol.19 , pp. 346-361
    • Dausch, J.G.1    Nixon, D.W.2
  • 20
    • 0024578399 scopus 로고
    • Allium vegetables and reduced risk of stomach cancer
    • You, W-C, Blot, WJ, Chang, Y-S, Ershow, A, Yang, ZT, et al.: Allium vegetables and reduced risk of stomach cancer. JNCI 81, 162-164, 1989.
    • (1989) JNCI , vol.81 , pp. 162-164
    • You, W.-C.1    Blot, W.J.2    Chang, Y.-S.3    Ershow, A.4    Yang, Z.T.5
  • 22
    • 0001079940 scopus 로고
    • Bioactive organosulfur compounds of garlic and garlic products. Role in reducing blood lipids
    • Lawson, LD: Bioactive organosulfur compounds of garlic and garlic products. Role in reducing blood lipids. Am Chem Soc Symp Ser 534, 306-330, 1993.
    • (1993) Am Chem Soc Symp Ser , vol.534 , pp. 306-330
    • Lawson, L.D.1
  • 23
    • 0026667521 scopus 로고
    • Metabolism of garlic constituents in the isolated perfused rat liver
    • Egen-Schwind, C, Eckard, R, and Kemper, FH: Metabolism of garlic constituents in the isolated perfused rat liver. Planta Med 58, 301-305, 1992.
    • (1992) Planta Med , vol.58 , pp. 301-305
    • Egen-Schwind, C.1    Eckard, R.2    Kemper, F.H.3
  • 24
    • 0027762678 scopus 로고
    • Pre-hepatic fate of the organosulfur compounds derived from garlic (Allium sativum)
    • Lawson, LD, and Wang, ZJ: Pre-hepatic fate of the organosulfur compounds derived from garlic (Allium sativum). Planta Med 59 Suppl, A688-A689, 1993.
    • (1993) Planta Med , vol.59 , Issue.SUPPL.
    • Lawson, L.D.1    Wang, Z.J.2
  • 25
    • 0000750035 scopus 로고
    • Volatile garlic odor components: Gas phases and adsorbed exhaled air analysed by headspace gas chromatography-mass spectrometry
    • Laakso, I, Seppänen-Laakso, T, Hiltunen, R, Müller, B, Jansen, H, et al.: Volatile garlic odor components: gas phases and adsorbed exhaled air analysed by headspace gas chromatography-mass spectrometry. Planta Med 55, 257-261, 1989.
    • (1989) Planta Med , vol.55 , pp. 257-261
    • Laakso, I.1    Seppänen-Laakso, T.2    Hiltunen, R.3    Müller, B.4    Jansen, H.5
  • 26
    • 84985204580 scopus 로고
    • Odour components of human breath after the ingestion of grated raw garlic
    • Minami, T, Boku, T, Inada, K, Monta, M, and Okazaki, Y: Odour components of human breath after the ingestion of grated raw garlic. J Food Sci 54, 763-765, 1989.
    • (1989) J Food Sci , vol.54 , pp. 763-765
    • Minami, T.1    Boku, T.2    Inada, K.3    Monta, M.4    Okazaki, Y.5
  • 27
    • 0001244535 scopus 로고
    • Allium chemistry: Identification of natural abundance organoselenium compounds in human breath after ingestion of garlic using gas chromatography with atomic emission detection
    • Cai, X-J, Block, E, Uden, PC, Quimby, BD, and Sullivan, JJ: Allium chemistry: identification of natural abundance organoselenium compounds in human breath after ingestion of garlic using gas chromatography with atomic emission detection. J Agric Food Chem 43, 1751-1753, 1995.
    • (1995) J Agric Food Chem , vol.43 , pp. 1751-1753
    • Cai, X.-J.1    Block, E.2    Uden, P.C.3    Quimby, B.D.4    Sullivan, J.J.5
  • 30
    • 0023739534 scopus 로고
    • Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse
    • Sparnins, VL, Barany, G, and Wattenberg, LW: Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis 9, 131-134, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 131-134
    • Sparnins, V.L.1    Barany, G.2    Wattenberg, L.W.3
  • 31
    • 0023221785 scopus 로고
    • Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer
    • Wargovich, MJ: Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer. Carcinogenesis 8, 487-489, 1987.
    • (1987) Carcinogenesis , vol.8 , pp. 487-489
    • Wargovich, M.J.1
  • 32
    • 0027290648 scopus 로고
    • Chemoprevention of colon carcinogenesis by organosulfur compounds
    • Reddy, BS, Rao, CV, Rivenson, AA, and Kelloff, G: Chemoprevention of colon carcinogenesis by organosulfur compounds. Cancer Res 53, 3493-3498, 1993.
    • (1993) Cancer Res , vol.53 , pp. 3493-3498
    • Reddy, B.S.1    Rao, C.V.2    Rivenson, A.A.3    Kelloff, G.4
  • 33
    • 0024378052 scopus 로고
    • Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes
    • Wattenberg, LW, Sparnins, VL, and Barany, G: Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes. Cancer Res 49, 2689-2692, 1989.
    • (1989) Cancer Res , vol.49 , pp. 2689-2692
    • Wattenberg, L.W.1    Sparnins, V.L.2    Barany, G.3
  • 34
    • 0028946622 scopus 로고
    • Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes
    • Haber, D, Siess, M-H, Canivenc-Lavier, M-C, Le Bon, A-M, and Suschetet, M: Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes. J Toxicol Environ Health 44, 423-434, 1995.
    • (1995) J Toxicol Environ Health , vol.44 , pp. 423-434
    • Haber, D.1    Siess, M.-H.2    Canivenc-Lavier, M.-C.3    Le Bon, A.-M.4    Suschetet, M.5
  • 35
    • 0031569814 scopus 로고    scopus 로고
    • Glutathione S-transferases of female A/J mouse lung and their induction by anticarcinogenic organosulfides from garlic
    • Hu, X, and Singh, SV: Glutathione S-transferases of female A/J mouse lung and their induction by anticarcinogenic organosulfides from garlic. Arch Biochem Biophys 340, 279-286, 1997.
    • (1997) Arch Biochem Biophys , vol.340 , pp. 279-286
    • Hu, X.1    Singh, S.V.2
  • 36
    • 0030869443 scopus 로고    scopus 로고
    • Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice
    • Srivastava, SK, Hu, X, Xia, H, Zaren, HA, Chatterjee, ML, et al.: Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice. Cancer Lett 118, 61-67, 1997.
    • (1997) Cancer Lett , vol.118 , pp. 61-67
    • Srivastava, S.K.1    Hu, X.2    Xia, H.3    Zaren, H.A.4    Chatterjee, M.L.5
  • 37
    • 0028281363 scopus 로고
    • Modification of hepatic drug-metabolizing enzymes in rat fed naturally occurring allyl sulphides
    • Haber, D, Siess, M-H, de Waziers, I, Beaune, P, and Suschetet, M: Modification of hepatic drug-metabolizing enzymes in rat fed naturally occurring allyl sulphides. Xenobiotica 24, 169-182, 1994.
    • (1994) Xenobiotica , vol.24 , pp. 169-182
    • Haber, D.1    Siess, M.-H.2    De Waziers, I.3    Beaune, P.4    Suschetet, M.5
  • 38
    • 0030956997 scopus 로고    scopus 로고
    • Differential induction of glutathione redox-cycle enzymes by anti-carcinogenic organosulfides from garlic
    • Singh, SV, Mack, LM, Xia, H, Srivastava, SK, Hu, X, et al.: Differential induction of glutathione redox-cycle enzymes by anti-carcinogenic organosulfides from garlic. Clin Chem Enzyme Commun 7, 287-297, 1997.
    • (1997) Clin Chem Enzyme Commun , vol.7 , pp. 287-297
    • Singh, S.V.1    Mack, L.M.2    Xia, H.3    Srivastava, S.K.4    Hu, X.5
  • 39
    • 0001503158 scopus 로고
    • A convenient synthesis of symmetrical disulfides
    • Hase, TA, and Peräkylä, H: A convenient synthesis of symmetrical disulfides. Synth Commun 12, 947-950, 1982.
    • (1982) Synth Commun , vol.12 , pp. 947-950
    • Hase, T.A.1    Peräkylä, H.2
  • 40
    • 77957000392 scopus 로고
    • DT diaphorase
    • Ernster, L: DT diaphorase. Methods Enzymol 10, 309-317, 1967.
    • (1967) Methods Enzymol , vol.10 , pp. 309-317
    • Ernster, L.1
  • 41
    • 0016275313 scopus 로고
    • Glutathione S-transferases: The first enzymatic step in mercapturic acid formation
    • Habig, WH, Pabst, MJ, and Jakoby, WB: Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem 249, 7130-7139, 1974.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 42
    • 0028189058 scopus 로고
    • Bioactivation of thiols by one-electron oxidation
    • MW Anders and W Dekant (eds). New York: Academic
    • Munday, R: Bioactivation of thiols by one-electron oxidation. In Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds, MW Anders and W Dekant (eds). New York: Academic, 1994, pp 237-270.
    • (1994) Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds , pp. 237-270
    • Munday, R.1
  • 43
    • 0002213949 scopus 로고
    • Allium sativum and Allium ursinum: Chemistry, pharmacology and medicinal applications
    • Reuter, HD, and Sendl, A: Allium sativum and Allium ursinum: chemistry, pharmacology and medicinal applications. Econ Med Plant Res 6, 55-113, 1994.
    • (1994) Econ Med Plant Res , vol.6 , pp. 55-113
    • Reuter, H.D.1    Sendl, A.2
  • 44
    • 24744434696 scopus 로고    scopus 로고
    • Peeling the onion: Organosulfur and -selenium phytochemicals in genus Allium plants
    • Block, E, Calvey, EM, Gillies, CW, Gillies, JZ, and Uden, P: Peeling the onion: organosulfur and -selenium phytochemicals in genus Allium plants. Recent Adv Phytochem 31, 1-30, 1997.
    • (1997) Recent Adv Phytochem , vol.31 , pp. 1-30
    • Block, E.1    Calvey, E.M.2    Gillies, C.W.3    Gillies, J.Z.4    Uden, P.5
  • 45
    • 0002205003 scopus 로고    scopus 로고
    • Role of phytochemicals in chronic disease prevention
    • PA Lachance (ed). Trumbull, CT: Food & Nutrition Press
    • Guhr, G, and Lachance, PA: Role of phytochemicals in chronic disease prevention. In Nutraceuticals: Designer Foods III: Garlic, Soy and Licorice, PA Lachance (ed). Trumbull, CT: Food & Nutrition Press, 1997, pp 311-364.
    • (1997) Nutraceuticals: Designer Foods III: Garlic, Soy and Licorice , pp. 311-364
    • Guhr, G.1    Lachance, P.A.2
  • 46
    • 33751157708 scopus 로고
    • Comparative toxicity of prop(en)yl disulfides derived from Alliaceae: Possible involvement of 1-propenyl disulfides in onion-induced hemolytic anemia
    • Munday, R, and Manns, E: Comparative toxicity of prop(en)yl disulfides derived from Alliaceae: possible involvement of 1-propenyl disulfides in onion-induced hemolytic anemia. J Agric Food Chem 42, 959-962, 1994.
    • (1994) J Agric Food Chem , vol.42 , pp. 959-962
    • Munday, R.1    Manns, E.2
  • 47
    • 0026682872 scopus 로고
    • Propionic acid and the phenomenon of rodent forestomach tumorigenesis: A review
    • Harrison, PTC: Propionic acid and the phenomenon of rodent forestomach tumorigenesis: a review. Food Chem Toxicol 30, 333-340, 1992.
    • (1992) Food Chem Toxicol , vol.30 , pp. 333-340
    • Harrison, P.T.C.1
  • 48
    • 0030693162 scopus 로고    scopus 로고
    • Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides
    • Siess, M-H, Le Bon, A-M, Canivenc-Lavier, M-C, and Suschetet, M: Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides. Cancer Lett 120, 195-201, 1997.
    • (1997) Cancer Lett , vol.120 , pp. 195-201
    • Siess, M.-H.1    Le Bon, A.-M.2    Canivenc-Lavier, M.-C.3    Suschetet, M.4
  • 49
    • 0022356047 scopus 로고
    • Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs
    • Benson, AM, and Barretto, PB: Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs. Cancer Res 45, 4219-4223, 1985.
    • (1985) Cancer Res , vol.45 , pp. 4219-4223
    • Benson, A.M.1    Barretto, P.B.2
  • 50
    • 0028127980 scopus 로고
    • Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: Correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes
    • Posner, GH, Cho, C-G, Green, JV, Zhang, Y, and Talalay, P: Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes. J Med Chem 37, 170-176, 1994.
    • (1994) J Med Chem , vol.37 , pp. 170-176
    • Posner, G.H.1    Cho, C.-G.2    Green, J.V.3    Zhang, Y.4    Talalay, P.5
  • 52
    • 0025369383 scopus 로고
    • Glutathione S-transferase subunit induction patterns of brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: A new approach for the identification of inducing xenobiotics
    • Bogaards, JJP, van Ommen, B, Falke, HE, Willems, MI, and van Bladeren, PJ: Glutathione S-transferase subunit induction patterns of brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics. Food Chem Toxicol 28, 81-88, 1990.
    • (1990) Food Chem Toxicol , vol.28 , pp. 81-88
    • Bogaards, J.J.P.1    Van Ommen, B.2    Falke, H.E.3    Willems, M.I.4    Van Bladeren, P.J.5
  • 53
    • 0029901681 scopus 로고    scopus 로고
    • Effect of oltipraz, α-tocopherol, β-carotene and phenethylisothiocyanate on rat oesophageal, gastric, colonic and hepatic glutathione, glutathione S-transferase and peroxidase
    • van Lieshout, EMM, Peters, WHM, and Jansen, JBMJ: Effect of oltipraz, α-tocopherol, β-carotene and phenethylisothiocyanate on rat oesophageal, gastric, colonic and hepatic glutathione, glutathione S-transferase and peroxidase. Carcinogenesis 17, 1439-1445, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 1439-1445
    • Van Lieshout, E.M.M.1    Peters, W.H.M.2    Jansen, J.B.M.J.3
  • 54
    • 0028122102 scopus 로고
    • Ellagic acid induces NAD(P)H:Quinone reductase through activation of the antioxidant responsive element of the rat NAD(P)H:Quinone reductase gene
    • Barch, DH, and Rundhaugen, LM: Ellagic acid induces NAD(P)H:quinone reductase through activation of the antioxidant responsive element of the rat NAD(P)H:quinone reductase gene. Carcinogenesis 15, 2065-2068, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 2065-2068
    • Barch, D.H.1    Rundhaugen, L.M.2
  • 55
    • 17944400154 scopus 로고    scopus 로고
    • Differential induction of NAD(P)H:Quinone oxidoreductase by anti-carcinogenic organosulfides from garlic
    • Singh, SV, Pan, SS, Srivastava, SK, Xia, H, Hu, X, et al.: Differential induction of NAD(P)H:quinone oxidoreductase by anti-carcinogenic organosulfides from garlic. Biochem Biophys Res Commun 244, 917-920, 1998.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 917-920
    • Singh, S.V.1    Pan, S.S.2    Srivastava, S.K.3    Xia, H.4    Hu, X.5
  • 56
    • 0031910337 scopus 로고    scopus 로고
    • NAD(P)H:Quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductaseactivated metabolites of benzo(a)pyrene quinones
    • Joseph, P, and Jaiswal, AK: NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductaseactivated metabolites of benzo(a)pyrene quinones. Br J Cancer 77, 709-719, 1998.
    • (1998) Br J Cancer , vol.77 , pp. 709-719
    • Joseph, P.1    Jaiswal, A.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.