Hepatitis C virus-specific CD4+ T cells: Do they help or damage?

Gastroenterology

Volumn 117, Issue 4, 1999, Pages 1012-1014

  Naoumov, N V ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN SPECIFICITY; EDITORIAL; HELPER CELL; HEPATITIS C; HOST RESISTANCE; HUMAN; INFECTION RESISTANCE; LIVER TRANSPLANTATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS INHIBITION; VIRUS TRANSMISSION;

EID: 0032833185     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70361-6     Document Type: Editorial

References (29)

1. Consensus Statement EASL International Consensus Conference on hepatitis C J Hepatol 30 1999 956 961
2. HP Dienes H Popper W Arnold H Lobeck Histologic observations in human hepatitis non-A, non-B Hepatology 2 1982 562 571
3. S Brillanti M Foli S Gaiani C Masci M Miglioli L Barbara Persistent hepatitis C viraemia without liver disease Lancet 341 1993 464 465
4. O Chazouilleres M Kim C Combs L Ferrell P Bacchetti J Roberts NL Ascher P Neuwald J Wilber M Urdea S Quan R Sanchez-Pescador TL Wright Quantitation of hepatitis C virus RNA in liver transplant recipients Gastroenterology 106 1994 994 999
5. S Vento F Cainelli F Mirandola L Cosco G Di Perri M Solbiati T Ferraro E Concia Fulminant hepatitis on withdrawal of chemotherapy in carriers of hepatitis C virus Lancet 347 1996 92 93
6. MJ Koziel The role of immune responses in the pathogenesis of hepatitis C virus infection J Viral Hepat 4 suppl 2 1997 31 41
7. G Del Prete E Maggi S Romagnani Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease Lab Invest 70 1994 299 306
8. H Diepolder R Zachoval R Hoffmann EA Wierenga T Santantonio M-C Jung D Eichenlaub GR Pape Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection Lancet 346 1995 1006 1007
9. G Missale R Bertoni V Lamonaca A Valli M Massari C Mori MG Rumi M Houghton F Fiaccadori C Ferrati Different clinical behaviors of acute hepatitis C infection are associated with different vigor of the anti-viral cell-mediated immune response J Clin Invest 98 1996 706 714
10. ME Cramp P Carucci S Rossol S Chokshi G Maertens R Williams NV Naoumov Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients with hepatitis C viraemia Gut 44 1999 424 429
11. JM Koziel D Dudley N Afdhal QL Choo R Houghton R Ralston BD Walker Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV J Virol 67 1993 7522 7532
12. B Rehermann K-M Chang JG McHutchinson R Kokka M Houghton FV Chisari Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection J Clin Invest 98 1996 1432 1440
13. DR Nelson CG Marousis GL Davis CM Rice J Wong M Houghton JYN Lau The role of hepatitis C virus–specific cytotoxic T lymphocytes in chronic hepatitis J Immunol 158 1997 1473 1481
14. DK Wong DD Dudley NH Afdhal J Dienstag CM Rice L Wang M Houghton BD Walker MJ Koziel Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection J Immunol 160 1998 1479 1488
15. + T-cell response in acute hepatitis C Gastroenterology 117 1999 933 941
16. + response to hepatitis C and severity of recurrence after liver transplantation Gastroenterology 117 1999 926 932
17. Marinos G, Rossol S, Carucci P, Wong PYN, Donaldson P, Hussain MJ, Vergani D, Portmann BC, Williams R, Naoumov NV. Immunopathogenesis of hepatitis B recurrence after liver transplantation. Transplantation (in press).
18. P Carucci EJ Gane S Riordan S Rossol M Houghton NV Naoumov R Williams Hepatitis C virus–specific T helper cell responses in recurrent hepatitis C after liver transplantation (abstr) J Hepatol 26 suppl 1 1997 145
19. P Botarelli MR Brunetto MA Minutello P Calvo D Unutmaz AJ Weiner Q-L Choo JR Shuster G Kuo F Bonino M Houghton S Abrignani T-lymphocyte response to hepatitis C virus in different clinical courses of infection Gastroenterology 104 1993 580 587
20. H Schupper P Hayashi J Scheffel S Aceituno T Paglieroni PV Holland JB Zeldis Peripheral-blood mononuclear cell responses to recombinant hepatitis C virus antigens in patients with chronic hepatitis C Hepatology 18 1993 1055 1060
21. MU Mondelli Is there a role for immune responses in the pathogenesis of hepatitis C? J Hepatol 25 1996 232 238
22. B Rehermann A Takaki A Liebetrau S Luda U Seifert K Salha M Manns M Wiese Characterization of the cytotoxic and helper T cell response in patients 18 years after a single source outbreak of HCV infection (abstr) Hepatology 26 1997 406A
23. S Cooper AL Erickson EJ Adams J Kansopon AJ Weiner DY Chien M Houghton P Parham CM Walker Analysis of a successful immune response against hepatitis C virus Immunity 110 1999 439 449
24. AJ Zajac JN Blattman K Murali-Krishna DJ Sourdive M Suresh JD Altman R Ahmed Viral immune evasion due to persistence of activated T cells without effort function J Exp Med 188 1998 2205 2213
25. SA Kalams BD Walker The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses J Exp Med 188 1998 2199 2204
26. X-S He B Rehermann FX Lopez-Labrador J Boisvert R Cheung J Mumm H Wedemeyer M Berenguer TL Wright MM Davis HB Greenberg Quantitative analysis of hepatitis C virus–specific CD8+ T cells in peripheral blood and liver using peptide-MHC tetramers Proc Natl Acad Sci USA 96 1999 5692 5697
27. A Bertoletti MM D'Elios C Boni M De Carli AL Zignego M Durazzo G Missale AA Penna F Fiaccadori G Del Prete C Ferrari Different cytokine profiles of intrahepatic T cells in chronic hepatitis B and hepatitis C virus infections Gastroenterology 112 1997 193 199
28. J Napoli GA Bishop PH McGuinness DM Painter GW McCaughan Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th2-associated cytokines Hepatology 24 1996 759 765
29. PT Donaldson The interrelationship between hepatitis C virus and HLA Eur J Clin Invest 29 1999 280 283