Selectins and β2-integrins mediate post-ischaemic venular adhesion of polymorphonuclear leukocytes, but not capillary plugging, in isolated hearts

Pflugers Archiv European Journal of Physiology

Volumn 438, Issue 4, 1999, Pages 479-485

  Habazettl, Helmut ^a   Kupatt, Christian ^b   Zahler, Stefan ^b   Becker, Bernhard F ^b   Messmer, Konrad ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Adhesion molecules; Fucoidin; Integrin; Myocardial reperfusion injury; Polymorphonuclear leukocytes; Selectin

Indexed keywords

CD18 ANTIGEN; CELL ADHESION MOLECULE; FLUORESCEIN ISOTHIOCYANATE; FUCOIDIN; INTEGRIN; SELECTIN;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; GUINEA PIG; HEART MUSCLE ISCHEMIA; LEUKOCYTE ADHERENCE; MALE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION;

EID: 0032826992     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240051065     Document Type: Article

References (31)

1. 1. Menger MD, Rücker M, Vollmar B (1997) Capillary dysfunction in striated muscle ischemia/reperfusion: on the mechanisms of capillary "no-reflow". Shock 8:2-7
2. 2. Engler RL, Schmid-Schönbein GW, Pavelec PS (1983) Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. Am J Pathol 111:98-111
3. 3. Bagge U, Amundson B, Lauritzen C (1980) White blood cell deformability and plugging of skeletal muscle capillaries in hemorrhagic shock. Acta Physiol Scand 108:159-163
4. 4. Carlos TM, Harlan JM (1994) Leukocyte-endothelial adhesion molecules. Blood 84:2068-2101
5. 5. Romson JL, Hook BG, Kunkel SL, Abrams GD, Schorck MA, Lucchesi BR (1983) Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 67:1016-1023
6. 6. Kolsky ER, Julia PL, Buckberg GD, Quillen JE, Acar C (1991) Studies of controlled reperfusion after ischemia. XXII. Reperfusate composition: effects of leukocyte depletion of blood and blood cardioplegic reperfusates after acute coronary occlusion. J Thorac Cardiovasc Surg 101:350-359
7. 7. Byrne JG, Appleyard RF, Lee CC, Couper GS, Scholl FG, Laurence RG, Cohn LH (1992) Controlled reperfusion of the regionally ischemic myocardium with leukocyte-depleted blood reduces stunning, the no-reflow phenomenon, and infaret size. J Thorac Cardiovasc Surg 72:66-72
8. 8. Kupatt C, Habazettl H, Zahler S, Weber C, Becker BF, Messmer K, Gerlach H (1997) ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury. Cardiovasc Res 36:386-395
9. 9. Sheridan FM, Cole PG, Ramage D (1996) Leukocyte adhesion to the coronary microvasculature during ischemia and reperfusion in an in vivo canine model. Circulation 93:1784-1787
10. 10. Omata M, Matsui N, Inomata N, Ohno T (1997) Protective effects of polysaccharide fucoidin on myocardial ischemia-reperfusion injury in rats. J Cardiovasc Pharmacol 30:717-724
11. 11. Lefer AM (1995) Role of selectins in myocardial ischemia-reperfusion injury. Ann Thorac Surg 60:773-777
12. 12. Lefer DJ, Shandelya SM, Serrano CVJ, Becker LC, Kuppusamy P, Zweier JL (1993) Cardioprotective actions of a monoclonal antibody against CD-18 in myocardial ischemia-reperfusion injury. Circulation 88:1779-1787
13. 13. Ma XL, Lefer DJ, Lefer AM, Rothlein R (1992) Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion. Circulation 86:937-946
14. 14. Ley K, Linnemann G, Meinen M, Stoolman LM, Gaethgens P (1993) Fucoidin, but not yeast polyphosphomannan PPME, inhibits leukocyte rolling in venules of the rat mesentery. Blood 81:177-185
15. 15. Zahler S, Kowalski C, Brosig A, Kupatt C, Becker BF, Gerlach E (1997) The function of neutrophils isolated by a magnetic antibody cell separation technique is not altered in comparison to a density gradient centrifugation method. J Immunol Methods 200:173-179
16. 16. Zahler S, Kupatt C, Seligmann C, Kowalski C, Becker BF, Gerlach E (1997) Retention of leucocytes in reperfused, isolated hearts does not cause haemodynamically relevant permanent capillary plugging. Pflügers Arch 433:713-720
17. 17. Holm S (1979) A simple sequentially rejective multiple test procedure. Scand J Stat 6:65-70
18. 18. Lucchesi BR (1994) Complement, neutrophils and free radicals: mediators of reperfusion injury. Arzneimittelforschung 44:420-432
19. 19. Mazzoni MC, Borgström P, Intaglietta M, Arfors K-E (1989) Lumenal narrowing and endothelial cell swelling in skeletal muscle capillaries during hemorrhagic shock. Circ Shock 29:27-39
20. 20. Harris AG, Skalak TC (1993) Leukocyte cytoskelelal structure determines capillary plugging and network resistance. Am J Physiol 265:H1670-1675
21. 21. Jolly SR, Kane WJ, Hook BG, Abrams GD, Kunkel SL, Lucchesi BR (1986) Reduction of myocardial infarct size by neutrophil depletion: effect of duration of occlusion. Am Heart J 112:682-690
22. 22. Andrian UH von, Chambers JD, McEvoy LM, Bargatze RF, Arfors KE, Butcher EC (1991) Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo. Proc Natl Acad Sci USA 88:7538-7542
23. 23. Hiramatsu O, Kimura A, Yada T, Yamamoto T, Ogasawara Y, Goto M, Tsujioka K, Kajiya F (1992) Phasic characteristics of arterial inflow and venous outflow of right ventricular myocardium in dogs. Am J Physiol 262:H1422-1427
24. 24. Kimura A, Hiramatsu O, Yamamoto T, Ogasawara Y, Yada T, Goto M, Tsujioka K, Kajiyu F (1992) Effect of coronary stenosis on phasic pattern of septal artery in dogs. Am J Physiol 262:H1690-1698
25. 25. Stecher DA, Engel P, Miller AS, Sheetz MP, Tedder TF (1997) Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes. J Immunol 159:952-963
26. 26. Tanuka H, Sukhova GK, Swanson SJ, Cybulsky MI, Schoen FJ, Libby P (1994) Endothelial and smooth muscle cells express leukocyte adhesion molecules heterogeneously during acute rejection of rabbit cardiac allografts. Am J Pathol 144: 938-951
27. 27. Rinder CS, Gaal D, Student LA, Smith BR (1994) Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg 107:280-288
28. 28. Massberg S, Enders G, Leiderer R, Eisenmenger S, Vestweber D, Krombach F, Messmer K (1998) Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood 92:507-515
29. 29. Zibari GB, Brown MF, Burney DL, Granger N, McDonald JC (1998) Role of P-selectin in the recruitment of leukocytes in mouse liver exposed to ischemia and reperfusion. Transplant Proc 30:2327-2330
30. 30. Kuebler WM, Kuhnle GE, Groh J, Goetz AE (1997) Contribution of selectins to leucocyte sequestration in pulmonary microvessels by intravital microscopy in rabbits. J Physiol (Lond) 501:375-386
31. 31. Kuijper PH, Gallardo-Torres HI, Linden JA van der, Lammers JW, Sixma JJ, Koenderman L, Zwaginga JJ (1996) Platelet-dependent primary hemostasis promotes selectin-and integrin-mediated neutrophil adhesion to damaged endothelium under flow conditions. Blood 87:3271-3281