ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury

Cardiovascular Research

Volumn 36, Issue 3, 1997, Pages 386-395

  Kupatt, Christian ^a   Habazettl, Helmut ^b   Zahler, Stefan ^a   Weber, Christian ^a   Becker, Bernhard F ^a   Messmer, Konrad ^b   Gerlach, Eckehart ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cilazaprilat; Coronary microcirculation; Fluorescence microscopy; Leukocyte adhesion; Myocardial stunning; Nitric oxide

Indexed keywords

CD11B ANTIGEN; CELL ADHESION MOLECULE; CILAZAPRILAT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; N(G) NITROARGININE; NITRIC OXIDE; RHODAMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CORONARY ARTERY BLOOD FLOW; GUINEA PIG; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; ISOLATED HEART; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; MICROVASCULATURE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; STUNNED HEART MUSCLE;

ANALYSIS OF VARIANCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CELL ADHESION; CILAZAPRIL; CORONARY VESSELS; FLOW CYTOMETRY; GUINEA PIGS; MACROPHAGE-1 ANTIGEN; MALE; MICROSCOPY, FLUORESCENCE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NEUTROPHIL ACTIVATION; NEUTROPHILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROARGININE; PERFUSION;

EID: 0031444134     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00191-0     Document Type: Article

References (40)

1. Braunwald E., Kloner R.A. The stunnned myocardium: Prolonged, postischemic ventricular dysfunction. Circulation. 66:1982;1146-1149.
2. Bolli R., Patel B.S., Hartley C.J., Thormbvy J.I., Jeroudi M.O., Roberts R. Nonuniform transmural recovery of contractile function in stunned myocardium. Am J Physil. 257:1989;H375-385.
3. Seccombe J.F., Schaff H.V. Coronary artery endothelial function after myocardial ischemia and reperfusion. Ann Thorac Surg. 60:1995;778-788.
4. Maes A., Van de Werf F., Nuyts J., Bormans G., Desmet W., Mortelmans L. Impaired myocardial tissue perfusion early after successful thrombolysis. Impact on myocardial flow, metabolism, and function at late follow up. Circulation. 92:1995;2072-2078.
5. Ragosta M., Camarano G., Kaul S., Powers E.R., Sarembock I.J., Gimple L.W. Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction. New insights using myocardial contrast echocardiography, Circulation. 89:1994;2562-2569.
6. Sawa Y., Taniguchi K., Kadoba K., Nishimura M., Ichikawa H., Amemiya A., Kuratani T., Matsuda H. Leukocyte depletion attenuates reperfusion injury in patients with left ventricular hypertrophy. Circulation. 93:1996;1640-1646.
7. Chatelain P., Latour J.-G., Tran D., De Lorgeril M., Dupras G., Bourassa M. Neutrophil accumulation in experimental myocardial infarcts: relation with extent of injury and effect of reperfusion. Circulation. 75:1987;1083-1090.
8. Go L.O., Murry C.E., Richard V.K., Weischedel G.R., Jennings R.B., Reimer K.A. Myocardial neutrophil accumulation during reperfusion after reversible or irreversible ischemic injury. Am J Physiol. 255:1988;H1188-1198.
9. Kraemer R., Mullane K.M. Neutrophils delay functional recovery of the post-hypoxic heart of the rabbit. J Pharmacol Exp Ther. 251:1989;620-626.
10. Tanaka M., Brooks S.E., Richard V.J., FitzHarris G.P., Stoler R.C., Jennings R.B., Arfors K.E., Reimer K.A. Effect of anti-CD18 antibody on myocardial neutrophil accumulation and infarct size after ischemia and reperfusion in dogs. Circulation. 87:1993;526-535.
11. Sheridan F.M., Cole P.G., Ramage M.S. Leukocyte adhesion to the coronary microvasculature during ischemia and reperfusion in an in vivo canine model. Circulation. 63:1996;1784-1787.
12. Shandelya S.M.L., Kuppusamy P., Weisfeldt M.L., Zweier J.L. Evaluation of the role of polymorphonuclear leukocytes on contractile function in myocardial reperfusion injury. Circulation. 87:1993;536-546.
13. Smith E.F. III, Egan J.W., Bugelski P.J., Hillegass L.M., Hill D.E., Griswold D.E. Temporal relation between neutrophil accumulation and myocardial reperfusion injury. Am J Physiol. 255:1988;H1060-1068.
14. Schmid-Schönbein G. Capillary plugging by granulocytes and the no-reflow phenomenon in the microcirculation. Fed Proc. 46:1987;2397-2401.
15. Simpson P.J., Todd R.F., Fantone J.C., Mickelson J.K., Griffin J.D., Lucchesi B.R. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion. J Clin Invest. 81:1988;624-629.
16. Lefer D.J., Shandelya S.M.L., Serrano C.V., Becker L.C., Kuppusamy P., Zweier J.L. Cardioprotective actions of a monoclonal antibody against CD-18 in myocardial ischemia-reperfusion injury. Circulation. 88:1993;1779-1787.
17. 2-integrins in vivo. Proc Natl Acad Sci USA. 88:1991;7538-7542.
18. Carlos T.M., Harlan J.M. Leukocyte-endothelial adhesion molecules. Blood. 84:1994;2068-2101.
19. Hartman J.C., Wall T.M., Hullinger T.G., Shebuski R. Reduction of myocardial infarct size in rabbits by ramiprilat: reversal by the bradykinin antagonist HOE 140. J Cardiovasc Pharmacol. 21:1993;996-1003.
20. Di Pasquale P., Paterna S., Valenza M., Valdes L., Albano V., Trombino G., Vitrano G., Cannizzaro S., Licata G., Albiero R. Effects of captopril on myocardial protection during cardioplegia. Int J Cardiol. 42:1993;225-230.
21. Zughaib M.E., Sun J.Z., Bolli R. Effect of angiotensin-converting enzyme inhibitors on myocardial ischemia/reperfusion injury: an overview. Basic Res Cardiol. 88:1993;155-167.
22. Muller C.A.M., Opie L.H., Peisach M., Pineda C.A. Chronic oral pretreatment with the angiotensin converting enzyme inhibitor, trandolapril, decreases ventricular fibrillation in acute ischaemia and reperfusion. Eur Heart J. 15:1994;988-996.
23. Kitakaze M., Minamino T., Node K., Komamura K., Shinozaki Y., Mori H., Kosaka H., Inoue M., Hori M., Kamada T. Beneficial effects of inhibition of angiotensin-converting enzyme on ischemic myocardium during coronary hypoperfusion in dogs. Circulation. 92:1995;950-961.
24. Massoudy P., Becker B.F., Gerlach E. Bradykinin accounts for improved postischemic function and decreased glutathione release of guinea pig heart treated with the angiotensin-converting enzyme inhibitor ramiprilat. J Cardiovasc Pharmacol. 23:1994;632-639.
25. Tanonaka K., Kamiyama T., Takezono A., Sakai K., Takeo S. Beneficial effects of angiotensin I converting enzyme inhibitor on post-ischemic contractile function of perfused rat heart. J Mol Cell Cardiol. 28:1996;1659-1670.
26. Kubes P., Suzuki M., Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA. 88:1991;4651-4655.
27. Raschke P., Becker B.F., Leipert B., Schwartz L.M., Zahler S., Gerlach E. Postischemic dysfunction of the heart induced by small numbers of neutrophils via formation of hypochlorous acid. Basic Res Cardiol. 88:1993;321-339.
28. Kupatt C., Zahler S., Seligmann C., Massoudy P., Becker B.F., Gerlach E. Nitric oxide mitigates leukocyte adhesion and vascular leak after myocardial ischemia. J Mol Cell Cardiol. 28:1996;643-654.
29. Zahler S., Kowalski C., Brosig A., Kupatt C., Becker B.F., Gerlach E. The function of neutrophils isolated by a magnetic antibody cell separation technique is not altered in comparison to a density gradient method. J Immunol Meth. 200:1997;173-179.
30. Raschke P., Becker B.F. Adenosine and PAF dependent mechanisms lead to myocardial reperfusion injury by neutrophils after brief ischemia. Cardiovasc Res. 29:1995;569-576.
31. Massoudy P., Becker B.F., Gerlach E. Nitric oxide accounts for postischemic cardioprotection resulting from angiotensin-converting enzyme inhibition: indirect evidence for a radical scavenger effect in isolated guinea pig heart. J Cardiovasc Pharmacol. 25:1995;440-447.
32. Bolli R., Jeroudi M.O., Patel B.S., DuBose C.M., Lai E.K., Roberts R., McKay P.B. Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proc Natl Acad Sci USA. 86:1989;4695-4699.
33. Lewis M.S., Whatley R.E., Cain P., McIntyre T.M., Prescott S.M., Zimmerman G.A. Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. J Clin Invest. 82:1988;2045-2055.
34. Fraticelli A., Serrano C.V., Bochner B.S., Capogrossi M.C., Zweier J.L. Hydrogen peroxide and superoxide modulate leukocyte adhesion molecule expression and leukocyte endothelial adhesion. Biochim Biophys Acta. 1310:1996;251-259.
35. Baumgarten C.R., Linz W., Kunkel G., Schoelkens B.A., Wiemer G. Ramiprilat increases bradykinin outflow from isolated hearts of rat. Br J Pharmacol. 108:1993;293-295.
36. Suematsu M., Tamatani T., Delano F.A., Miyasaka M., Forrest M., Suzuki H., Schmid-Schonbein G.W. Microvascular oxidative stress preceding leukocyte activation elicited by in vivo nitric oxide suppression. Am J Physiol. 266:1994;H2410-2415.
37. Aruoma O.I., Akanmu D., Cecchini R., Halliwell B. Evaluation of the ability of the angiotensin-converting enzyme inhibitor captorpil to scavenge reactive oxygen species. Chem Biol Interact. 77:1991;303-314.
38. Hughes A.K., Stricklett P.K., Padilla E., Kohan D.E. Effect of reactive oxygen sepcies on endothelin-1 production by human mesangial cells. Kidney Int. 49:1996;181-189.
39. Brunner F., Kukovetz W.R. Postischemic antiarrhythmic effects of angiotensin-converting enyme inhibitors. Circulation. 94:1996;1752-1761.
40. Mickelson J.K., Lakkis N.M., Villarreal-Levy G., Hughes B.J., Smith C.W. Leukocyte activation with platelet adhesion after coronary angioplasty: a mechanism for recurrent disease. J Am Coll Cardiol. 28:1996;345-353.