Entry sites for oral vaccines and drugs: A role for M cells, enterocytes and dendritic cells?

Seminars in Immunology

Volumn 11, Issue 3, 1999, Pages 217-224

  Kaiserlian, Dominique ^b   Etchart, Nathalie ^a  

^a INSERM   (France)

^b NONE

Author keywords

Dendritic cells; Enterocytes; Haptens; Live vector; M cells; Naked DNA; Proteins

Indexed keywords

VACCINE;

ANTIGEN PRESENTING CELL; DENDRITIC CELL; EPITHELIUM CELL; INTESTINE CELL; M CELL; ORAL DRUG ADMINISTRATION; REVIEW; VACCINATION;

EID: 0032812079     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1999.0177     Document Type: Article

References (50)

1. Neutra MR. Current concepts in mucosal immunity. V. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system. Am J Physiol. 274:1998.
2. Maric I, Holt PG, Perdue MH, Bienenstock J. Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine. J Immunol. 156:1996;1408-1414.
3. Spalding DM, Williamson SI, Koopman WJ, McGhee JR et al. Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures. J Exp Med. 160:1984;941-946.
4. Fayette J, Dubois B, Vandenabeele S, Bridon JM, Vanbervliet B, Durand I, Banchereau J, Caux C, Brière F et al. Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2. J Exp Med. 185:1997;1909-1918.
5. Heyman M, Ducroc R, Desjeux JF et al. Horseradish peroxidase transport across adult rabbit jejunum in vitro. Am J Physiol. 242:1982;558-564.
6. Ducroc R, Heyman M, Beaufrère B, Morgat JL, Desjeux JF. Horseradish peroxidase transport across rabbit jejunum and Peyer's patches in vitro. Am J Physiol. 245:1983;54-58.
7. Gonnella PA, Wilmore DW. Co-localization of class II antigen and exogenous antigen in the rat enterocyte. J Cell Sci. 106:1993;937-940.
8. Strobel S, Mowat AM. Immune responses to dietary antigens: oral tolerance. Immunol Today. 19:1998;173-181.
9. Hershberg RM et al. Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells. J Clin Invest. 102:1998;792-803.
10. Galliaerde V, Desvignes C, Peyron E, Kaiserlian D. Oral tolerance to haptens: intestinal epithelial cells from 2,4-dinitrochlorobenzene-fed mice inhibit hapten-specific T cell activation in vitro. Eur J Immunol. 25:1995;1385-1390.
11. Vidal K, Samarut C, Magaud J-P, Revillard J-P, Kaiserlian D. Unexpected lack of reactivity of allogeneic anti-Ia monoclonal antibodies with MHC class II molecules expressed by mouse intestinal epithelial cells. J Immunol. 151:1993;4642-4650.
12. Hershberg RM, Framson PE, Cho DH, Lee LY, Kovats S, Beitz J, Blum JS, Nepom GT. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing. J Clin Invest. 100:1997;204-215.
13. Blumberg RS, Terhorst C, Bleicher P, McDermott FV, Allan CH, Landau SB, Trier JS, Balk SP. Expression of a nonpolymorphic MHC class I-like molecule, CD1D, by human intestinal epithelial cells. J Immunol. 147:1991;2518-2524.
14. Jullien D, Afanassieff M, Claudy A, Nicolas JF, Kaiserlian D. CD1: une nouvelle famille de molécules présentatrices d'antigènes aux caractéristiques singulières. Méd Sci. 15:1999;7-14.
15. Lee DJ, Abeyratne A, Carson DA, Corr M. Induction of an antigen-specific, CD1-restricted cytotoxic T lymphocyte response in vivo. J Exp Med. 187:1998;433-438.
16. Balk SP, Ebert EC, Blumenthal RL, McDermott FV, Wucherpfennig KW, Landau SB, Blumberg RS. Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science. 253:1991;1411-1415.
17. Carter PB, Collins FM. The route of enteric infection in normal mice. J Exp Med. 139:1974;1189-1203.
18. Hohmann AW, Schmidt G, Rowley D. Intestinal colonization and virulence of Salmonella in mice. Infect Immun. 22:1978;763-770.
19. Makino S, Sasakawa C, Kamata K, Kurata T, Yoshikawa M. A genetic determinant required for continuous reinfection of adjacent cells on large plasmid in Shigella flexneri 2a. Cell. 46:1986;551-556.
20. Inman LR, Cantey JR. Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhea in the rabbit. J Clin Invest. 71:1983;1-8.
21. Madara JL, Trier JS, Neutra MR. Structural changes in the plasma membrane accompanying differentiation of epithelial cells in human and monkey small intestine. Gastroenterology. 78:1980;963-975.
22. Moore R, Carlson S, Madara JL. Rapid barrier restitution in an in vitro model of intestinal epithelial injury. Lab Invest. 60:1989;237-244.
23. Perdomo OJJ, Cavaillon JM, Huerre M, Ohayon H, Gounon p, Sansonetti PJ. Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis. J Exp Med. 180:1994;1307-1319.
24. Portnoy DA, Chakraborty T, Goebel W, Cossart P. Molecular determinants of Listeria monocytogenes pathogenesis. Infect Immun. 60:1992;1263-1267.
25. Gaillard JL, Finley BB. Effects of cell polarization and differentiation on entry of Listeria monocytogenes into the enterocyte-like Caco-2 cell line. Infect Immun. 64:1996;1299-1308.
26. Pron B, Boumaila C, Jaubert F, Sarnacki S, Monnet JP, Berche P, Gaillard JL. Comprehensive study of the intestinal stage of listeriosis in a rat ligated ileal loop system. Infect Immunol. 66:1998;747-755.
27. Holmgren J, Lönnroth I, Mansson JE, Svennerholm L. Interaction of cholera toxin and membrane GM1 ganglioside of small intestine. Proc Natl Acad Sci USA. 72:1975;2520-2524.
28. Lencer WI, Moe S, Rufo PA, Madara JL. Transcytosis of cholera toxin subunits across model human intestinal epithelia. Proc Natl Acad Sci USA. 92:1995;10094-10098.
29. Lindner J, Geczy AF, Russell-Jones GJ. Identification of the site of uptake of the E. coli heat-labile enterotoxin, LTB. Scand J Immunol. 40:1994;564-572.
30. Wolf JL, Rubin DH, Finberg R, Kauffman RS, Sharpe AH, Trier JS, Fields BN. Intestinal M cells: a pathway for entry of reovirus into the host. Science. 212:1981;471-472.
31. Wolf JL, Kauffman RS, Finberg R, Dambrauskas R, Fields BN, Trier JS. Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine. Gastroenterology. 85:1983;291-300.
32. Bomsel M. Transcytosis of infectious human immunodefi ciency virus across a tight human epithelial cell line barrier. Nat Med. 3:1997;42-47.
33. Holt PG, Haining S, Nelson DJ, Sedgwick JD. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J Immunol. 153:1994;256-261.
34. Hamilton-Easton A, Eichelberger M. Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice. Virology. 69:1995;6359-6366.
35. Kelsall B, Strober W. Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch. J Exp Med. 183:1996;237-247.
36. Hopkins, SA, Kraehenbuhl, JP, Dendritic cells of the murine Peyer's patches colocalize with Salmonella typhimurium avirulent mutants in the subepithelial dome, Dendritic Cells in Fundamental and Clinical Immunology, Castagnoli, Ricciardi, 105, 109, Plenum Press, New York, 1997.
37. Spira AI, Marx PA, Patterson BK et al. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med. 183:1996;215-225.
38. Frankel S, Wenig BM, Burke AP, Mannan P, Thompson LR, Abbondanzo SL, Nelson AM, Pope M, Steinman RM. Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of adenoid. Science. 272:1996;115-118.
39. Liu LM, MacPherson GG. Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo. J Exp Med. 177:1993;1299-1307.
40. Barrett AW, Ross DA, Goodacre JA. Purified human oral mucosal Langerhans cells function as accessory cells in vitro. Clin Exp Immunol. 92:1993;158-163.
41. +effector T cells in vivo. Clin Exp Immunol. 113:1998;386-393.
42. Eriksson K, Ahlfors E, George-Chandy A, Kaiserlian D, Czerkinsky C. Antigen presentation in the murine oral epithelium. Immunology. 88:1996;147-152.
43. +T cell-mediated contact sensitivity. J Exp Med. 189:1999;779-786.
44. Rosenthal KL, Gallichan WS. Challenges for vaccination against se xually-transmitted diseases: induction and long-term maintenance of mucosal immune responses in the female genital tract. Sem Immunol. 9:1997;303-314.
45. Belyakov IM, Derby MA, Ahlers JD, Kelsall BL, Earl P, Moss B, Strober W, Berzofsky JA. Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge. Proc Natl Acad Sci USA. 95:1998;1709-1714.
46. Etchart N, Buckland R, Liu M, Wild TF, Kaiserlian D. Class I-restricted CTL induction induced by mucosal immunization with naked DNA encoding measles virus hemagglutinin. J Gen Virol. 78:1997;1577-1580.
47. Darji A, Guzman CA, Gerstel B, Wachholz P, Timmis KN, Wehland J, Chakraborty T, Weiss S. Oral somatic transgene vaccination using attenuated S. typhimurium. Cell. 91:1997;765-775.
48. During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nat Med. 4:1998;1131-1135.
49. +T cells after gene gun immunization. J Exp Med. 188:1998;1075-1082.
50. Kilshaw PJ. Expression of the mucosal T cell integrin αM290β7 by a major subpopulation of dendritic cells in mice. Eur J Immunol. 23:1993;3365-3368.