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Volumn 19, Issue 3 A, 1999, Pages 1827-1832

G2/M checkpoint is p53-dependent and independent after irradiation in five human sarcoma cell lines

Author keywords

Apoptosis; G2 M response; p53; Radiation sensitivity; Sarcoma cell lines

Indexed keywords

PROTEIN P53;

EID: 0032801666     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (50)
  • 2
    • 0030232710 scopus 로고    scopus 로고
    • The p53 gene as a modifier of intrinsic radiosensitivity: Implications for radiotherapy
    • Bristow RG, Benchimol S, and Hill RP: The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother Oncol 40: 197-223, 1996.
    • (1996) Radiother Oncol , vol.40 , pp. 197-223
    • Bristow, R.G.1    Benchimol, S.2    Hill, R.P.3
  • 4
    • 0025876591 scopus 로고
    • The p53 tumor suppressor gene
    • Levine AJ, Momand J, and Finlay CA: The p53 tumor suppressor gene. Nature 351: 453-456, 1991.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 6
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by temperature-sensitive mutant of p53
    • Michalovitz D, Halevy Q, and Oren M: Conditional inhibition of transformation and of cell proliferation by temperature-sensitive mutant of p53. Cell 62: 671-680, 1990.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, Q.2    Oren, M.3
  • 7
    • 0004939229 scopus 로고
    • Evidence for a second cell cycle block at G2/M by p53
    • Stewart N, Hicks GG, Paraskevas F, and Mowat M: Evidence for a second cell cycle block at G2/M by p53. Oncogene 12: 237-245, 1995.
    • (1995) Oncogene , vol.12 , pp. 237-245
    • Stewart, N.1    Hicks, G.G.2    Paraskevas, F.3    Mowat, M.4
  • 8
    • 0028980494 scopus 로고
    • p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
    • Agarwal ML, Agarwal A, Taylor WR, and Stark GR: p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci USA 92: 8493-8497, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8493-8497
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Stark, G.R.4
  • 9
    • 0026129706 scopus 로고
    • Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with oncogenes H-ras and v-myc
    • Mc Kenna WG, Iliakis G, Weiss MC, Bernhard EJ, and Muschel RJ: Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with oncogenes H-ras and v-myc. Radiat Res 125: 283-287, 1991.
    • (1991) Radiat Res , vol.125 , pp. 283-287
    • Mc Kenna, W.G.1    Iliakis, G.2    Weiss, M.C.3    Bernhard, E.J.4    Muschel, R.J.5
  • 10
    • 0028925622 scopus 로고
    • Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells
    • Palayoor ST, Macklis RM, Bump EA, and Coleman CN: Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells. Radiat Res 141: 235-243, 1995.
    • (1995) Radiat Res , vol.141 , pp. 235-243
    • Palayoor, S.T.1    Macklis, R.M.2    Bump, E.A.3    Coleman, C.N.4
  • 11
    • 0030052074 scopus 로고    scopus 로고
    • Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: Influence of H-ras on G2 delay
    • Mc Kenna WG, Bernhard EJ, Markiewicz DA, Rudoltz MS, Maity A, and Muschel R: Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on G2 delay. Oncogene 12: 237-245, 1996.
    • (1996) Oncogene , vol.12 , pp. 237-245
    • Mc Kenna, W.G.1    Bernhard, E.J.2    Markiewicz, D.A.3    Rudoltz, M.S.4    Maity, A.5    Muschel, R.6
  • 12
    • 0028168452 scopus 로고
    • Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity
    • Nagasawa H, Keng P, Harley R, Dahlberg W, and Little JB: Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity. Int J Radiat Biol 66: 373-379, 1994.
    • (1994) Int J Radiat Biol , vol.66 , pp. 373-379
    • Nagasawa, H.1    Keng, P.2    Harley, R.3    Dahlberg, W.4    Little, J.B.5
  • 13
    • 0028230158 scopus 로고
    • The role of constitutive and inducible processes in the response of human squamous cell carcinoma cell lines to ionizing radiation
    • Schwartz JL: The role of constitutive and inducible processes in the response of human squamous cell carcinoma cell lines to ionizing radiation. Radiat Res 138 (Suppl 1): S37-39, 1994.
    • (1994) Radiat Res , vol.138 , Issue.1 SUPPL.
    • Schwartz, J.L.1
  • 14
    • 0024997178 scopus 로고
    • The occurrence of apoptosis, abnormal mitoses, cells dying in mitosis and micronuclei in a human melanoma xenograft exposed to single dose irradiation
    • Falkvoll KH: The occurrence of apoptosis, abnormal mitoses, cells dying in mitosis and micronuclei in a human melanoma xenograft exposed to single dose irradiation. Strahlentherapie und Onkologie 166: 487-492, 1990.
    • (1990) Strahlentherapie und Onkologie , vol.166 , pp. 487-492
    • Falkvoll, K.H.1
  • 16
    • 0028238034 scopus 로고
    • Analyses of mitotic cell death caused by radiation in mouse leukaemia L5178Y cells: Apoptosis is the ultimate form of cell death following mitotic failure
    • Tauchi H, and Sawada S: Analyses of mitotic cell death caused by radiation in mouse leukaemia L5178Y cells: apoptosis is the ultimate form of cell death following mitotic failure. Int J Radiat Biol 65: 449-455, 1994.
    • (1994) Int J Radiat Biol , vol.65 , pp. 449-455
    • Tauchi, H.1    Sawada, S.2
  • 18
    • 0031821640 scopus 로고    scopus 로고
    • Molecular characterization and liposomal transfection of a p53-mutated cell line established from a poorly undifferentiated leiomyosarcoma
    • Meye A, Bache M, Hinze R, Schmidt H, Würl P, Holzhausen HJ, Rath FW, and Taubert H: Molecular characterization and liposomal transfection of a p53-mutated cell line established from a poorly undifferentiated leiomyosarcoma. Int J Oncol 13: 241-248, 1998.
    • (1998) Int J Oncol , vol.13 , pp. 241-248
    • Meye, A.1    Bache, M.2    Hinze, R.3    Schmidt, H.4    Würl, P.5    Holzhausen, H.J.6    Rath, F.W.7    Taubert, H.8
  • 20
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, and Harris CC: Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 21
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 22
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke AR, Purdie CA, and Harrison DJ:. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852, 1993.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.A.2    Harrison, D.J.3
  • 23
    • 0027285380 scopus 로고
    • P53 mutations increase resistance to ionizing radiation
    • Lee JM, and Bernstein A: p53 mutations increase resistance to ionizing radiation. Proc. Natl Acad Sci USA 90: 5742-5746, 1993.
    • (1993) Proc. Natl Acad Sci USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 24
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, and Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    De Housman4
  • 25
    • 0027319521 scopus 로고
    • p53 is required for for radiation-induced apoptosis in mouse thymocytes
    • Lowe SW, Schmitt EM, Smith SE, Osborne BA and Jacks T: p53 is required for for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849, 1993.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.E.3    Osborne, B.A.4    Jacks, T.5
  • 26
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumorsuppressor pathway in cell lines of the National Cancer Institute Anticancer Drug Screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor PM, Jackman J, and Bae I: Characterization of the p53 tumorsuppressor pathway in cell lines of the National Cancer Institute Anticancer Drug Screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 57: 4285-4300, 1997.
    • (1997) Cancer Res , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3
  • 27
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins DD, Demers GW, and Galloway D: Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res 56: 892-898, 1996.
    • (1996) Cancer Res , vol.56 , pp. 892-898
    • Hawkins, D.D.1    Demers, G.W.2    Galloway, D.3
  • 28
  • 30
    • 0027176479 scopus 로고
    • p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
    • Brachmann DG, Beckett M, Graves D, Haraf D, Vokes E, and Weichselbaum RR: p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res 53: 3667-3669, 1993.
    • (1993) Cancer Res , vol.53 , pp. 3667-3669
    • Brachmann, D.G.1    Beckett, M.2    Graves, D.3    Haraf, D.4    Vokes, E.5    Weichselbaum, R.R.6
  • 32
    • 0030775165 scopus 로고    scopus 로고
    • Characterisation of the G1/S cell cycle checkpoint defect in lung carcinoma cells with different intrinsic radiosensitivities
    • Sirzen F, Heiden T, Nilsson A, Bergh J, Skog S, and Lewensohn R: Characterisation of the G1/S cell cycle checkpoint defect in lung carcinoma cells with different intrinsic radiosensitivities. Anticancer Res 17: 3381-3386, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 3381-3386
    • Sirzen, F.1    Heiden, T.2    Nilsson, A.3    Bergh, J.4    Skog, S.5    Lewensohn, R.6
  • 33
    • 0031840913 scopus 로고    scopus 로고
    • Radiation-induced apoptosis of human prostate cancer cells is independent of mutant p53 overexpression
    • Kyprianou N, and Rock S et al: Radiation-induced apoptosis of human prostate cancer cells is independent of mutant p53 overexpression. Anticancer Res 18: 897-905, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 897-905
    • Kyprianou, N.1    Rock, S.2
  • 35
    • 0029019437 scopus 로고
    • Radiation-induced apoptosis in human sarcoma and glioma cell lines
    • Stapper NJ, Stuschke M, Sak A, and Stuben G: Radiation-induced apoptosis in human sarcoma and glioma cell lines, Int J Cancer 62: 58-62, 1995.
    • (1995) Int J Cancer , vol.62 , pp. 58-62
    • Stapper, N.J.1    Stuschke, M.2    Sak, A.3    Stuben, G.4
  • 36
    • 0028936626 scopus 로고
    • Differential sensitivation of p53(-) and p53(+) cells to caffeine-induced radiosensitivation and override of G2 delay
    • Powel SN, De Frank JS, Connell P, Eogan M, Preffer F, Dombkowski D, Tang W, and Friend S: Differential sensitivation of p53(-) and p53(+) cells to caffeine-induced radiosensitivation and override of G2 delay. Cancer Res 55: 1643-1648, 1995.
    • (1995) Cancer Res , vol.55 , pp. 1643-1648
    • Powel, S.N.1    De Frank, J.S.2    Connell, P.3    Eogan, M.4    Preffer, F.5    Dombkowski, D.6    Tang, W.7    Friend, S.8
  • 38
    • 0030802463 scopus 로고    scopus 로고
    • Inhibition of radiation induced G2 delay potentiates cell death by apoptosis and /or the induction of giant cells with disrupted p53 function
    • Bracey TS, Williams AC, and Paraskeva C: Inhibition of radiation induced G2 delay potentiates cell death by apoptosis and /or the induction of giant cells with disrupted p53 function. Clin Cancer Res 3: 1371-81, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 1371-1381
    • Bracey, T.S.1    Williams, A.C.2    Paraskeva, C.3
  • 39
    • 0028946766 scopus 로고
    • Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression
    • Aloni-Grinstein R, Schwartz D, and Rotter V: Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression. EMBO-J 14: 1392-401, 1995.
    • (1995) EMBO-J , vol.14 , pp. 1392-1401
    • Aloni-Grinstein, R.1    Schwartz, D.2    Rotter, V.3
  • 41
  • 42
    • 0030700333 scopus 로고    scopus 로고
    • Role of wild type p53 in the G2 phase: Regulation of the irradiation-induced delay and DNA repair
    • Schwartz D, Almog N, Peled A, Goldfinger N, and Rotter V: Role of wild type p53 in the G2 phase: regulation of the irradiation-induced delay and DNA repair. Oncogene 15: 2597-2607, 1997.
    • (1997) Oncogene , vol.15 , pp. 2597-2607
    • Schwartz, D.1    Almog, N.2    Peled, A.3    Goldfinger, N.4    Rotter, V.5
  • 43
    • 0031029576 scopus 로고    scopus 로고
    • Expression of wild-type p53 increases etoposide cytotoxicity in M1 myeloid leukemia cells by facilitated G2 to M Transition: Implications for gene therapy
    • Skladanowski A and Larsen AK: Expression of wild-type p53 increases etoposide cytotoxicity in M1 myeloid leukemia cells by facilitated G2 to M Transition: Implications for gene therapy. Cancer Res 57: 818-823, 1997.
    • (1997) Cancer Res , vol.57 , pp. 818-823
    • Skladanowski, A.1    Larsen, A.K.2
  • 44
    • 0028978530 scopus 로고
    • Radiation induced apoptosis in human colorectal cell lines can occur in the absence of wildtype p53
    • Bracley TC, Miller JC, Preece A, and Paraskeva C: Radiation induced apoptosis in human colorectal cell lines can occur in the absence of wildtype p53. Oncogene 10: 2391-2396, 1995.
    • (1995) Oncogene , vol.10 , pp. 2391-2396
    • Bracley, T.C.1    Miller, J.C.2    Preece, A.3    Paraskeva, C.4
  • 46
    • 0031045270 scopus 로고    scopus 로고
    • Induction of p53 independent apoptosis associated with G2/M arrest following DNA damage in human colon cancer cell lines
    • Arita D, Kambe M, Ishioka C, and Kanamaru R: Induction of p53 independent apoptosis associated with G2/M arrest following DNA damage in human colon cancer cell lines, Jpn J Cancer Res 88: 39-43, 1997.
    • (1997) Jpn J Cancer Res , vol.88 , pp. 39-43
    • Arita, D.1    Kambe, M.2    Ishioka, C.3    Kanamaru, R.4
  • 47
    • 0030812174 scopus 로고    scopus 로고
    • Apoptosis in small intestinal epithelia from p53-null mice: Evidence for delayed, p53-independent G2/M-associated cell death after gamma-irradiation
    • Merritt AJ, Allen TD, Potten CS, and Hickman JA: Apoptosis in small intestinal epithelia from p53-null mice: evidence for delayed, p53-independent G2/M-associated cell death after gamma-irradiation. Oncogene 14: 2759-2766,1997.
    • (1997) Oncogene , vol.14 , pp. 2759-2766
    • Merritt, A.J.1    Allen, T.D.2    Potten, C.S.3    Hickman, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.