Dual energy X-ray absorptiometry assessment of fat mass distribution and its association with the insulin resistance syndrome

Diabetes Care

Volumn 22, Issue 8, 1999, Pages 1310-1317

  Paradisi, Giancarlo ^b   Smith, Lovell ^b   Burtner, Chris ^b   Leaming, Rosalind ^b   Garvey, W Timothy ^b   Hook, Ginger ^b   Johnson, Ann ^b   Cronin, Jessica ^b   Steinberg, Helmut O ^b   Baron, Alain D ^a  

^a INDIANA UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ABDOMEN; AREA UNDER THE CURVE; ARTICLE; BODY DISTRIBUTION; BODY FAT; BODY MASS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LEG; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; TRUNK;

ADIPOSE TISSUE; ADULT; BLOOD PRESSURE; BODY COMPOSITION; CARBOHYDRATES; DENSITOMETRY, X-RAY; EVALUATION STUDIES; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN RESISTANCE; LINEAR MODELS; LIPIDS; MALE; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; SYNDROME;

EID: 0032797005     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.22.8.1310     Document Type: Article

References (40)

1. Donahue RP, Abbott RD, Bloom E, Reed DM, Yano K: Central obesity and coronary heart disease in men. Lancet i:821-824, 1987
2. McPhillips JB, Barrett-Connor E, Wingard DL: Cardiovascular disease risk factors prior to the diagnosis of impaired glucose tolerance and non-insulin dependent diabetes mellitus in a community of older adults. Am J Epidemiol 131:443-453, 1990
3. Reaven GM: Banting Lecture 1988: Role of insulin resistance in human disease. Diabetes 37:1595-1607, 1988
4. Stern MP, Haffner SM: Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular disease. Arteriosclerosis 6:123-130, 1986
5. Meigs JB, D'Agostino RB Sr, Wilson PWF, Cupples LA, Nathan DM, Singer DE: Risk variable clustering in the insulin resistance syndrome: The Framingham Offspring Study. Diabetes 46:1594-1600, 1997
6. Bengtsson C, Bjorkelund C, Lapidus L, Lissner L: Associations of serum lipid concentrations and obesity with mortality in women: 20 year follow up of participants in prospective population study in Gothenberg, Sweden. BMJ 307:1385-1388, 1993
7. Björntorp P: Metabolic implications of body fat distribution. Diabetes Care 14: 1132-1143, 1991
8. Stern M, Haffner B: Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular disease. Arteriosclerosis 6:123-130, 1986
9. Lapidus L, Bengtsson C, Larsson B: Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden. BMJ 289:1257-1261, 1984
10. Larsson B, Svardsudd K, Welin L: Abdominal adipose tissue distribution, obesity and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. BMJ 288:1401-1404, 1984
11. Walton C, Lees B, Crook D, Worthington M, Godsland IF, Stevenson JC: Body fat distribution, rather than overall adiposity, influences serum lipids and lipoproteins in healthy men independently of age. Am J Med 99:459-464, 1995
12. Després J-P Nadeau A, Tremblay A, Ferland M, Moorjani S, Lupien PJ, Thériault G, Pinauk S, Bouchard C: Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes 38:304-309, 1989
13. Carlson LA, Hallberg D, Micheli H: Quantitative studies on the lipolytic response of human subcutaneous and omental adipose tissue to noradrenaline and theophylline. Acta Med Scand 185:465-469, 1969
14. Ostman J, Arner P, Engfeldt P, Kager L: Regional differences in the control of lipolysis in human adipose tissue. Metab Clin Exp 28:1198-1205, 1979
15. Efendic S: Catecholamines and metabolism of human adipose tissue: III. comparison between the regulation of lipolysis in omental and subcutaneous adipose tissue. Acta Med Scand 187:477-483, 1970
16. Bjorntorp P: "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Arteriosclerosis 10: 493-496, 1990
17. Pouliot M-C, Després J-P, Nadeau A, Moorjani S, Prud'Homme D, Lupien PJ, Tremblay A, Bouchard C: Visceral obesity in men: associations with glucose tolerance, plasma insulin, and lipoprotein levels. Diabetes 41:826-834, 1992
18. Park KS, Rhee BD, Lee KU, Kim SY, Lee HK, Koh CS, Min HK: Intra-abdominal fat is associated with a decreased insulin sensitivity in healthy young men. Metabolism 40:600-603, 1991
19. Després J-P, Moorjani S, Ferland M, Tremblay A, Lupien PJ, Nadeau A, Pinault S, Thériault G, Bouchard C: Adipose tissue distribution and plasma lipoprotein levels in obese women: importance of intraabdominal fat. Arteriosclerosis 9:203-210, 1989
20. Peins AN, Sothmann MS, Hennes MI, Lee MB, Wilson CR, Gustafson AB, Kissebah AH: Relative contribution of obesity and body fat distribution to alterations in glucose insulin homeostasis: predictive values of selected indices in premenopausal women. Am J Clin Nutr 49:758-764, 1989
21. Hunter GR, Kekes-Szabo T, Snyder SW, Nicholson C, Nyikos I, Berland L: Fat distribution, physical activity, and cardiovascular risk factors. Med Sci Sports Exerc 29:362-369, 1997
22. Goodpaster BH, Thaete FL, Simoneau J-A, Kelley DE: Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579-1585, 1997
23. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM: Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest 96: 88-98, 1995
24. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM: Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes 45:1684-1693, 1996
25. Baron AD, Wallace P, Olefsky JM: In vivo regulation of non-insulin-mediated and insulin-mediated glucose uptake by epinephrine. J Clin Endocrinol Metab 64: 889-893, 1987
26. Baron AD, Brechtel G, Wallace P, Edelman SV: Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am J Physiol 255:E769-E774, 1988
27. Haarbo J, Gotfredsen A, Hassager C, Christiansen C: Validation of body composition by dual energy X-ray absorptiometry (DEXA). Clin Physiol 11:331-341, 1991
28. Novak M: Colormetric ultramicro method for the determination of free fatty acids. J Lipid Res 6:431-433, 1965
29. Friedewald WT, Levy RT, Fredrickson DS: Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502, 1972
30. Ducimetiere P, Richard J, Cambien F: The pattern of subcutaneous fat distribution in middle-aged men and the risk of coronary heart disease: the Paris Prospective Study. Int J Obes 10:229-240, 1986
31. Plourde G: The role of radiologic methods in assessing body composition and related metabolic parameters. Nutr Rev 55: 289-296, 1997
32. Surcliffe JF: A review of in vivo experimental methods to determine the composition of the human body. Phys Med Biol 41: 791-833, 1996
33. Carey DG, Jenkins AB, Campbell LV, Freund J, Chisholm DJ: Abdominal fat and insulin resistance in normal and overweight women: direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. Diabetes 45: 633-638, 1996
34. Olefsky JM, Reaven GM, Farquhar JW: Effects of weight reduction on obesity: studies of carbohydrate and lipid metabolism. J Clin Invest 53:64-76, 1974
35. Hollenbeck C, Reaven GM: Variations in insulin-stimulated glucose uptake in healthy individuals with normal glucose tolerance. J Clin Endocrinol Metab 64: 1169-1173, 1987
36. Pedersen S, Borglum J, Schmitz O, Bak J, Sorensen N, Richelsen B: Abdominal obesity is associated with insulin resistance and reduced glycogen synthetase activity in skeletal muscle. Metabolism 42:998-1005, 1993
37. Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, Porte D Jr: Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: evidence for a hyperbolic function. Diabetes 42:1663-1672, 1993
38. Barakat HA, Mooney N, O'Brien K, Long S, Khazani PG, Pories W, Caro JF: Coronary heart disease risk factors in morbidly obese women with normal glucose tolerance. Diabetes Care 16:144-149, 1993
39. Olefsky JM, Farquhar JW, Reaven GM: Reappraisal of the role of insulin in hypertriglyceridemia. Am J Med 57:551-560, 1974
40. Tobey TA, Greenfield M, Kraemer F, Reaven GM: Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics and plasma triglyceride levels in normotriglyceridemic man. Metabolism 30:165-171, 1981