-
1
-
-
0023938398
-
Adjuvant activity of Escherichia coli heat labile enterotoxin and effect of induction of oral tolerance in mice to unrelated antigens
-
Clements, J. D., N. M. Hartzog, and F. L. Lyon. 1988. Adjuvant activity of Escherichia coli heat labile enterotoxin and effect of induction of oral tolerance in mice to unrelated antigens. Vaccine 6:269-277.
-
(1988)
Vaccine
, vol.6
, pp. 269-277
-
-
Clements, J.D.1
Hartzog, N.M.2
Lyon, F.L.3
-
2
-
-
0031979999
-
Mutational analysis of the role of ADP-ribosylation activity and GM1-binding activity in the adjuvant properties of the Escherichia coli heat-labile enterotoxin towards intranasally administered keyhole limpet hemocyanin
-
de Haan, L., I. K. Feil, W. R. Verweij, M. Holtrop, W. G. Hol, E. Agsteribbe, and J. Wilschut. 1998. Mutational analysis of the role of ADP-ribosylation activity and GM1-binding activity in the adjuvant properties of the Escherichia coli heat-labile enterotoxin towards intranasally administered keyhole limpet hemocyanin. Eur. J. Immunol. 28:1243-1250.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 1243-1250
-
-
De Haan, L.1
Feil, I.K.2
Verweij, W.R.3
Holtrop, M.4
Hol, W.G.5
Agsteribbe, E.6
Wilschut, J.7
-
3
-
-
0028985871
-
Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
-
Dickinson, B. L., and J. D. Clements. 1995. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 63:1617-1623.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1617-1623
-
-
Dickinson, B.L.1
Clements, J.D.2
-
4
-
-
0030066516
-
Induction of antigen-specific anti-bodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant
-
Di Tommaso, A., G. Saletti, M. Pizza, R. Rappuoli, G. Dougan, S. Abrignani, G. Douce, and M.-T. De Magistris. 1996. Induction of antigen-specific anti-bodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect. Immun. 64:974-979.
-
(1996)
Infect. Immun.
, vol.64
, pp. 974-979
-
-
Di Tommaso, A.1
Saletti, G.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
Abrignani, S.6
Douce, G.7
De Magistris, M.-T.8
-
5
-
-
0030940814
-
Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin
-
Douce, G., M. Fontana, M. Pizza, R. Rappuoli, and G. Dougan. 1997. Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin. Infect. Immun. 65:2821-2818.
-
(1997)
Infect. Immun.
, vol.65
, pp. 2821-12818
-
-
Douce, G.1
Fontana, M.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
-
6
-
-
0031802314
-
Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli
-
Douce, G., M. M. Giuliani, V. Giannelli, M. G. Pizza, R Rappuoli, and G. Dougan. 1998. Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli. Vaccine 16:1065-1073.
-
(1998)
Vaccine
, vol.16
, pp. 1065-1073
-
-
Douce, G.1
Giuliani, M.M.2
Giannelli, V.3
Pizza, M.G.4
Rappuoli, R.5
Dougan, G.6
-
7
-
-
0002863168
-
Mutant pertussis and Escherichia coli heat labile toxins as adjuvants for enhancing local and systemic immune responses to coadministered, nonliving antigens
-
M. M. Levine, G. C. Woodrow, J. Kaper, and G. S. Cobon (ed.). Marcel Dekker, New York, N.Y.
-
Douce, G., M. Pizza, M. Roberts, R. Rappuoli, and G. Dougan. 1997. Mutant pertussis and Escherichia coli heat labile toxins as adjuvants for enhancing local and systemic immune responses to coadministered, nonliving antigens, p. 253-263. In M. M. Levine, G. C. Woodrow, J. Kaper, and G. S. Cobon (ed.), New generation vaccines, 2nd ed. Marcel Dekker, New York, N.Y.
-
(1997)
New Generation Vaccines, 2nd Ed.
, pp. 253-263
-
-
Douce, G.1
Pizza, M.2
Roberts, M.3
Rappuoli, R.4
Dougan, G.5
-
8
-
-
0028918767
-
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants
-
Douce, G., C. Turcotte, I. Cropley, M. Roberts, M. Pizza, M. Domenghini, R. Rappuoli, and G. Dougan. 1995. Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. Proc. Natl. Acad. Sci. USA 92:1644-1648.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1644-1648
-
-
Douce, G.1
Turcotte, C.2
Cropley, I.3
Roberts, M.4
Pizza, M.5
Domenghini, M.6
Rappuoli, R.7
Dougan, G.8
-
9
-
-
0030959610
-
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum anti-body responses to expressed foreign antigens
-
Galen, J. E., O. G. Gomez-Duarte, G. A. Losonsky, J. L Halpern, C. S. Lauderbaugh, S. Kaintuck, M. K. Reymann, and M. M. Levine. 1997. A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum anti-body responses to expressed foreign antigens. Vaccine 15:700-708.
-
(1997)
Vaccine
, vol.15
, pp. 700-708
-
-
Galen, J.E.1
Gomez-Duarte, O.G.2
Losonsky, G.A.3
Halpern, J.L.4
Lauderbaugh, C.S.5
Kaintuck, S.6
Reymann, M.K.7
Levine, M.M.8
-
10
-
-
0031027336
-
Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop
-
Giannelli, V., M. R. Fontana, M. M. Giuliani, D. Guangcai, R. Rappuoli, and M. Pizza. 1997. Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop. Infect. Immun. 65:331-334.
-
(1997)
Infect. Immun.
, vol.65
, pp. 331-334
-
-
Giannelli, V.1
Fontana, M.R.2
Giuliani, M.M.3
Guangcai, D.4
Rappuoli, R.5
Pizza, M.6
-
11
-
-
0032489830
-
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
-
Giuliani, M. M., G. Del Giudice, V. Giannelli, G. Dougan, G. Douce, R Rappuoli, and M. Pizza. 1998. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J. Exp. Med. 187:1123-1132.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1123-1132
-
-
Giuliani, M.M.1
Del Giudice, G.2
Giannelli, V.3
Dougan, G.4
Douce, G.5
Rappuoli, R.6
Pizza, M.7
-
12
-
-
0027453689
-
Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant
-
Jackson, R. J., K. Fujihashi, J. Xu-Amano, H. Kiyono, C. O. ElsoN, and J. R McGhee. 1993. Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant. Infect. Immun. 61:4272-4279.
-
(1993)
Infect. Immun.
, vol.61
, pp. 4272-4279
-
-
Jackson, R.J.1
Fujihashi, K.2
Xu-Amano, J.3
Kiyono, H.4
Elson, C.O.5
McGhee, J.R.6
-
13
-
-
0021058990
-
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
-
Levine, M. M., J. B. Kaper, R. E. Black, and M. L. Clements. 1983. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev. 47:510-550.
-
(1983)
Microbiol. Rev.
, vol.47
, pp. 510-550
-
-
Levine, M.M.1
Kaper, J.B.2
Black, R.E.3
Clements, M.L.4
-
14
-
-
0022460378
-
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens
-
Lycke, N., and J. Holmgren. 1986. Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology 59:301-308.
-
(1986)
Immunology
, vol.59
, pp. 301-308
-
-
Lycke, N.1
Holmgren, J.2
-
15
-
-
0026699224
-
The adjuvant effect of Vibrio cholerae and Escherichia coli enterotoxins is linked to their ADP-ribosyltransferase activity
-
Lycke, N., T. Tsuji, and J. Holmgren. 1992. The adjuvant effect of Vibrio cholerae and Escherichia coli enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol. 22:2277-2281.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2277-2281
-
-
Lycke, N.1
Tsuji, T.2
Holmgren, J.3
-
16
-
-
0029852233
-
Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin
-
Magagnoli, C., R. Manetti, M. R Fontana, V. Giannelli, M. M. Giuliani, R Rappuoli, and M. Pizza. 1996. Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin. Infect. Immun. 64:5435-5438.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5435-5438
-
-
Magagnoli, C.1
Manetti, R.2
Fontana, M.R.3
Giannelli, V.4
Giuliani, M.M.5
Rappuoli, R.6
Pizza, M.7
-
17
-
-
0031986493
-
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
-
Marchetti, M., M. Rossi, V. Giannelli, M. M. Giuliani, M. Pizza, S. Censini, A. Covacci, P. Massari, C. Pagliaccia, R. Manetti, J. L. Telford, G. Douce, G. Dougan, R. Rappuoli, and P. Ghiara. 1998. Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant. Vaccine 16:33-37.
-
(1998)
Vaccine
, vol.16
, pp. 33-37
-
-
Marchetti, M.1
Rossi, M.2
Giannelli, V.3
Giuliani, M.M.4
Pizza, M.5
Censini, S.6
Covacci, A.7
Massari, P.8
Pagliaccia, C.9
Manetti, R.10
Telford, J.L.11
Douce, G.12
Dougan, G.13
Rappuoli, R.14
Ghiara, P.15
-
18
-
-
0027992673
-
A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit
-
Pizza, M., M. R. Fontana, M. M. Giuliani, M. Domenighini, C. Magagnoii, V. Giannelli, D. Nucci, W. Hol, R. Manetti, and R. Rappuoli. 1994. A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit. J. Exp. Med. 180: 2147-2153.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2147-2153
-
-
Pizza, M.1
Fontana, M.R.2
Giuliani, M.M.3
Domenighini, M.4
Magagnoii, C.5
Giannelli, V.6
Nucci, D.7
Hol, W.8
Manetti, R.9
Rappuoli, R.10
-
19
-
-
0029881522
-
Induction of pneumococcal polysaccharide-specific mucosal immune response by oral immunisation
-
VanCott, J. L., T. Kobayashi, M. Yamamoto, S. Pillai, J. R. McGhee, and H. Kiyono. 1996. Induction of pneumococcal polysaccharide-specific mucosal immune response by oral immunisation. Vaccine 14:392-398.
-
(1996)
Vaccine
, vol.14
, pp. 392-398
-
-
VanCott, J.L.1
Kobayashi, T.2
Yamamoto, M.3
Pillai, S.4
McGhee, J.R.5
Kiyono, H.6
-
20
-
-
0032219522
-
Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: Induction of systemic IgG and secretory IgA response in mice by intranasal immunisation with influenza virus surface antigen
-
Verweij, W. R., L. de Haan, M. Holtrop, E. Agsteribbe, R. Brands, G. J. Van Scharrenburg, and J. Wilschut. 1998. Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: induction of systemic IgG and secretory IgA response in mice by intranasal immunisation with influenza virus surface antigen. Vaccine 16:2069-2076.
-
(1998)
Vaccine
, vol.16
, pp. 2069-2076
-
-
Verweij, W.R.1
De Haan, L.2
Holtrop, M.3
Agsteribbe, E.4
Brands, R.5
Van Scharrenburg, G.J.6
Wilschut, J.7
-
21
-
-
0031929609
-
Effects of adjuvants on the immune response to allergens in a murine model of allergen inhalation: Cholera toxin induces a Th1-like response to Bet v 1, the major birch pollen antigen
-
Wiedermann, U., B. Jahn-Schmid, R. Fritsch, L. Bauer, H. Renz, D. Kraft, and C. Ebner. 1998. Effects of adjuvants on the immune response to allergens in a murine model of allergen inhalation: cholera toxin induces a Th1-like response to Bet v 1, the major birch pollen antigen. Clin. Exp. Immunol. 111:144-151.
-
(1998)
Clin. Exp. Immunol.
, vol.111
, pp. 144-151
-
-
Wiedermann, U.1
Jahn-Schmid, B.2
Fritsch, R.3
Bauer, L.4
Renz, H.5
Kraft, D.6
Ebner, C.7
-
22
-
-
0007205169
-
A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
-
Yamamoto, S., H. Kiyono, Y. Yamamoto, K. Imaoka, K. Fnjihashi, F. W. Van Ginkel, M. Noda, Y. Takeda, and J. R. McGhee. 1997. A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc. Natl. Acad. Sci. USA 94:5267-5272.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5267-5272
-
-
Yamamoto, S.1
Kiyono, H.2
Yamamoto, Y.3
Imaoka, K.4
Fnjihashi, K.5
Van Ginkel, F.W.6
Noda, M.7
Takeda, Y.8
McGhee, J.R.9
|