-
1
-
-
0029841601
-
Newly licensed drugs
-
Ferner RB. Newly licensed drugs. Br Med J. 1996;313:1157-1158.
-
(1996)
Br Med J
, vol.313
, pp. 1157-1158
-
-
Ferner, R.B.1
-
2
-
-
0027305993
-
Competing in drug safety
-
Edwards R. Competing in drug safety. Lancet. 1992;342:631-632.
-
(1992)
Lancet
, vol.342
, pp. 631-632
-
-
Edwards, R.1
-
3
-
-
0023272606
-
The contribution of epidemiology to the study of drugs
-
Porta MS, Hartzema AG. The contribution of epidemiology to the study of drugs. Drug Intell Clin Pharm. 1987;21:741-747.
-
(1987)
Drug Intell Clin Pharm
, vol.21
, pp. 741-747
-
-
Porta, M.S.1
Hartzema, A.G.2
-
4
-
-
0021350001
-
The lipid research clinics coronary primary prevention trial results. I. Reduction in the incidence of coronary heart disease
-
Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in the incidence of coronary heart disease. JAMA. 1984;251:351-364.
-
(1984)
JAMA
, vol.251
, pp. 351-364
-
-
-
5
-
-
0021349709
-
The lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol-lowering
-
Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol-lowering. JAMA. 1984;251:365-374.
-
(1984)
JAMA
, vol.251
, pp. 365-374
-
-
-
6
-
-
0023232216
-
Helsinki heart study: Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia
-
Frick MH, Elo O, Happa K, et al. Helsinki Heart Study: Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia. N Engl J Med. 1987;317:1237-1245.
-
(1987)
N Engl J Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
Elo, O.2
Happa, K.3
-
7
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The scandinavian simvastatin survival study (4 S)
-
Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4 S). Lancet. 1994;344:1383-1389.
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
8
-
-
0028883828
-
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
-
Sheperd J, Cobe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med. 1995;333:1301-1307.
-
(1995)
N Engl J Med
, vol.333
, pp. 1301-1307
-
-
Sheperd, J.1
Cobe, S.M.2
Ford, I.3
-
9
-
-
0028568193
-
Policosanol inhibits cholesterol biosynthesis and enhances LDL processing cultured human fibroblasts
-
Menéndez R, Fernández I, del Río A, et al. Policosanol inhibits cholesterol biosynthesis and enhances LDL processing cultured human fibroblasts. Biol Res. 1994;27:199-203.
-
(1994)
Biol Res
, vol.27
, pp. 199-203
-
-
Menéndez, R.1
Fernández, I.2
Del Río, A.3
-
10
-
-
0343052967
-
Cholesterol-lowering effects of policosanol on rabbits with hypercholesterolemia induced by a starch-casein diet
-
Menéndez R, Arruzazabala ML, Más R, et al. Cholesterol-lowering effects of policosanol on rabbits with hypercholesterolemia induced by a starch-casein diet. Br J Nutr. 1997;77:923-932.
-
(1997)
Br J Nutr
, vol.77
, pp. 923-932
-
-
Menéndez, R.1
Arruzazabala, M.L.2
Más, R.3
-
11
-
-
0028227198
-
Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment
-
Pons P, Rodríguez M, Robaina C, et al. Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment. Int J Clin Pharmacol Res. 1994;14:27-33.
-
(1994)
Int J Clin Pharmacol Res
, vol.14
, pp. 27-33
-
-
Pons, P.1
Rodríguez, M.2
Robaina, C.3
-
12
-
-
0027978416
-
One year efficacy and safety of policosanol in patients with type II hypercholesterolemia
-
Pons P, Rodriguez M, Más R, et al. One year efficacy and safety of policosanol in patients with type II hypercholesterolemia. Curr Ther Res. 1994;55:1084-1092.
-
(1994)
Curr Ther Res
, vol.55
, pp. 1084-1092
-
-
Pons, P.1
Rodriguez, M.2
Más, R.3
-
13
-
-
0028963194
-
Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia
-
Aneiros E, Más R, Calderón B, et al. Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia. Curr Ther Res. 1995;56:176-182.
-
(1995)
Curr Ther Res
, vol.56
, pp. 176-182
-
-
Aneiros, E.1
Más, R.2
Calderón, B.3
-
14
-
-
0029589212
-
A two year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinemia
-
Canetti M, Moreira M, Illnait J, et al. A two year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinemia. Int J Clin Pharmacol Res. 1995;15:159-165.
-
(1995)
Int J Clin Pharmacol Res
, vol.15
, pp. 159-165
-
-
Canetti, M.1
Moreira, M.2
Illnait, J.3
-
15
-
-
0029155739
-
Efficacy and tolerability of policosanol in elderly patients with type II hypercholesterolemia: A 12-month study
-
Castaño G, Canetti M, Moreira M, et al. Efficacy and tolerability of policosanol in elderly patients with type II hypercholesterolemia: A 12-month study. Curr Ther Res. 1995;56:819-828.
-
(1995)
Curr Ther Res
, vol.56
, pp. 819-828
-
-
Castaño, G.1
Canetti, M.2
Moreira, M.3
-
16
-
-
0029945522
-
Effects of policosanol on hypercholesterolemic patients with disturbances on serum biochemical indicators of hepatic function
-
Zardoya R, Tula L, Castaño G, et al. Effects of policosanol on hypercholesterolemic patients with disturbances on serum biochemical indicators of hepatic function. Curr Ther Res. 1996;57:568-577.
-
(1996)
Curr Ther Res
, vol.57
, pp. 568-577
-
-
Zardoya, R.1
Tula, L.2
Castaño, G.3
-
17
-
-
0030857721
-
A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia
-
Ortensi G, Gtadstein J, Valli H, Tesone PA. A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia. Curr Ther Res. 1997;58:390-401.
-
(1997)
Curr Ther Res
, vol.58
, pp. 390-401
-
-
Ortensi, G.1
Gtadstein, J.2
Valli, H.3
Tesone, P.A.4
-
18
-
-
0031406655
-
Effects of policosanol on primary hypercholesterolemia: A 3-year open-extension follow-up
-
Canetti MM, Moreira M, Más R, et al. Effects of policosanol on primary hypercholesterolemia: A 3-year open-extension follow-up. Curr Ther Res. 1997;58:868-875.
-
(1997)
Curr Ther Res
, vol.58
, pp. 868-875
-
-
Canetti, M.M.1
Moreira, M.2
Más, R.3
-
19
-
-
0031406593
-
A comparative study of policosanol versus pravastatin in patients with type II hypercholesterolemia
-
Benítez M, Romero C, Más R, et al. A comparative study of policosanol versus pravastatin in patients with type II hypercholesterolemia. Curr Ther Res. 1997;58:859-867.
-
(1997)
Curr Ther Res
, vol.58
, pp. 859-867
-
-
Benítez, M.1
Romero, C.2
Más, R.3
-
20
-
-
0031787854
-
Open-label study of the efficacy, safety, and tolerability of policosanol in patients with high global coronary risk
-
Castaño G, Más R, Fernándex JC, et al. Open-label study of the efficacy, safety, and tolerability of policosanol in patients with high global coronary risk. Curr Ther Res. 1998;59:737-745.
-
(1998)
Curr Ther Res
, vol.59
, pp. 737-745
-
-
Castaño, G.1
Más, R.2
Fernándex, J.C.3
-
21
-
-
0032970949
-
Effect of policosanol in patients with type II hypercholesterolemia plus two or moro additional coronary risk factors
-
Más R, Castaño G, Fernández JC, et al. Effect of policosanol in patients with type II hypercholesterolemia plus two or moro additional coronary risk factors. Clin Pharmacol Ther. 1999;65:439-447.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 439-447
-
-
Más, R.1
Castaño, G.2
Fernández, J.C.3
-
22
-
-
0028897637
-
Treatment of hypercholesterolemia in NIDDM with policosanol
-
Torres O, Agramonte AJ, Illnait J, et al. Treatment of hypercholesterolemia in NIDDM with policosanol. Diabetes Care. 1995;18:393-397.
-
(1995)
Diabetes Care
, vol.18
, pp. 393-397
-
-
Torres, O.1
Agramonte, A.J.2
Illnait, J.3
-
23
-
-
0031018756
-
Effects of policosanol on patients with non-insulin-dependent diabetes mellitus and hypercholesterolemia: A pilot study
-
Crespo N, Alvarez R, Más R, et al. Effects of policosanol on patients with non-insulin-dependent diabetes mellitus and hypercholesterolemia: A pilot study. Curr Ther Res. 1997;58:44-51.
-
(1997)
Curr Ther Res
, vol.58
, pp. 44-51
-
-
Crespo, N.1
Alvarez, R.2
Más, R.3
-
24
-
-
0027413130
-
Effects of policosanol on platelet aggregation in rats
-
Arruzazabala ML, Carbajal D, Más R, et al. Effects of policosanol on platelet aggregation in rats. Thromb Res. 1992;69:321-327.
-
(1992)
Thromb Res
, vol.69
, pp. 321-327
-
-
Arruzazabala, M.L.1
Carbajal, D.2
Más, R.3
-
25
-
-
0030295032
-
Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers
-
Arruzazabala ML, Valdés S, Más R, et al. Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers. Pharmacol Res. 1996;34:181-185.
-
(1996)
Pharmacol Res
, vol.34
, pp. 181-185
-
-
Arruzazabala, M.L.1
Valdés, S.2
Más, R.3
-
27
-
-
0002429418
-
Efecto del policosanol sobre la functión de las plaquetas en voluntarios sanos
-
Scazziota A, Pons S, Altman R. Efecto del policosanol sobre la functión de las plaquetas en voluntarios sanos. Rev Iberoamer Tromb Hemos. 1996;9:58-62.
-
(1996)
Rev Iberoamer Tromb Hemos
, vol.9
, pp. 58-62
-
-
Scazziota, A.1
Pons, S.2
Altman, R.3
-
28
-
-
0031962129
-
Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers
-
Carbajal D, Arruzazabala ML, Valdés S, Más R. Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers. Prostaglandins Leukot Essent Fatty Acids. 1998;58:61-64.
-
(1998)
Prostaglandins Leukot Essent Fatty Acids
, vol.58
, pp. 61-64
-
-
Carbajal, D.1
Arruzazabala, M.L.2
Valdés, S.3
Más, R.4
-
29
-
-
0031257654
-
Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers
-
Arruzazabala ML, Valdés S, Más R, et al. Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol Res. 1997;36:293-297.
-
(1997)
Pharmacol Res
, vol.36
, pp. 293-297
-
-
Arruzazabala, M.L.1
Valdés, S.2
Más, R.3
-
30
-
-
0001353911
-
Acute, subchronic and chronic toxicity of policosanol in rats
-
June 28-July 3; Rome, Italy. Abstract 248
-
Alemán CL, Rodeiro I, Noa M, et al. Acute, subchronic and chronic toxicity of policosanol in rats. In: Abstracts of the Sixth International Congress of Toxicology; June 28-July 3, 1992; Rome, Italy. Abstract 248.
-
(1992)
Abstracts of the Sixth International Congress of Toxicology
-
-
Alemán, C.L.1
Rodeiro, I.2
Noa, M.3
-
31
-
-
0027957267
-
A 12 month study of policosanol oral toxicity in Sprague-Dawley rats
-
Alemán C, Más R, Hernández C, et al. A 12 month study of policosanol oral toxicity in Sprague-Dawley rats. Toxicol Lett. 1994;70:77-87.
-
(1994)
Toxicol Lett
, vol.70
, pp. 77-87
-
-
Alemán, C.1
Más, R.2
Hernández, C.3
-
32
-
-
0028174497
-
Teratogenic and reproductive studies of policosanol in the rat and rabbit
-
Rodriguez MD, Garcín H. Teratogenic and reproductive studies of policosanol in the rat and rabbit. Teratog Carcinog Mutag. 1994;14:107-113.
-
(1994)
Teratog Carcinog Mutag
, vol.14
, pp. 107-113
-
-
Rodriguez, M.D.1
Garcín, H.2
-
33
-
-
0028144949
-
Toxicity of policosanol in Beagle dogs: One year study
-
Mesa AR, Más R, Noa M, et al. Toxicity of policosanol in Beagle dogs: One year study. Toxicol Lett. 1994;73:81-90.
-
(1994)
Toxicol Lett
, vol.73
, pp. 81-90
-
-
Mesa, A.R.1
Más, R.2
Noa, M.3
-
34
-
-
0028033806
-
Carcinogenicity of policosanol in Sprague Dawley rats: A 24 month study
-
Alemán CL, Más R, Noa M, et al. Carcinogenicity of policosanol in Sprague Dawley rats: A 24 month study. Teratog Carcinog Mutag. 1994;14:239-249.
-
(1994)
Teratog Carcinog Mutag
, vol.14
, pp. 239-249
-
-
Alemán, C.L.1
Más, R.2
Noa, M.3
-
35
-
-
0031729810
-
Policosanol: Results of a postmarketing surveillance study on 27,879 patients
-
Fernández L, Más R, Illnait J, Fernández JC, Policosanol: Results of a postmarketing surveillance study on 27,879 patients. Curr Ther Res. 1998;59:717-722.
-
(1998)
Curr Ther Res
, vol.59
, pp. 717-722
-
-
Fernández, L.1
Más, R.2
Illnait, J.3
Fernández, J.C.4
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