메뉴 건너뛰기




Volumn 59, Issue 10, 1998, Pages 717-722

Policosanol: Results of a postmarketing surveillance study of 27,879 patients

Author keywords

Cholesterol lowering drugs; Policosanol; Postmarketing surveillance

Indexed keywords

POLICOSANOL;

EID: 0031729810     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(98)85030-3     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 0029841601 scopus 로고    scopus 로고
    • Newly licensed drugs
    • Ferner RB. Newly licensed drugs. BMJ. 1996;313:1157-1158.
    • (1996) BMJ , vol.313 , pp. 1157-1158
    • Ferner, R.B.1
  • 2
    • 0024279780 scopus 로고
    • Guidelines on postmarketing surveillance
    • Joint Committee of Association of the British Pharmaceutical Industry, British Medical Association, the Committee of Safety of Medicines, and the Royal College of General Practitioners. Guidelines on postmarketing surveillance. BMJ. 1988;296:399-400.
    • (1988) BMJ , vol.296 , pp. 399-400
  • 3
    • 0023551298 scopus 로고
    • Potential role of postmarketing research
    • Venulet J. Potential role of postmarketing research. Drugs Exp Clin Res. 1987;13:673-683.
    • (1987) Drugs Exp Clin Res. , vol.13 , pp. 673-683
    • Venulet, J.1
  • 4
    • 0021769745 scopus 로고
    • Postmarketing surveillance of adverse reactions to drugs
    • Rawlins MD. Postmarketing surveillance of adverse reactions to drugs. BMJ. 1984;288: 879-880.
    • (1984) BMJ , vol.288 , pp. 879-880
    • Rawlins, M.D.1
  • 5
    • 0029973317 scopus 로고    scopus 로고
    • Effect of policosanol on the hepatic cholesterol biosynthesis of normocholesterolemic rats
    • Menéndez R, Amor M, González RM, et al. Effect of policosanol on the hepatic cholesterol biosynthesis of normocholesterolemic rats. Biol Res. 1996;29:253-257.
    • (1996) Biol Res. , vol.29 , pp. 253-257
    • Menéndez, R.1    Amor, M.2    González, R.M.3
  • 6
    • 0028568193 scopus 로고
    • Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts
    • Menéndez R, Fernández I, del Rio A, et al. Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts. Biol Res. 1994;27:199-203.
    • (1994) Biol Res. , vol.27 , pp. 199-203
    • Menéndez, R.1    Fernández, I.2    Del Rio, A.3
  • 7
    • 0343052967 scopus 로고    scopus 로고
    • Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolemia induced by a wheat starch-casein diet
    • Menéndez R, Arruzazabala ML, Más R, et al. Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolemia induced by a wheat starch-casein diet. Br J Nutr. 1997;77:923-932.
    • (1997) Br J Nutr. , vol.77 , pp. 923-932
    • Menéndez, R.1    Arruzazabala, M.L.2    Más, R.3
  • 8
    • 0028577437 scopus 로고
    • Cholesterol-lowering effects of policosanol in rabbits
    • Arruzazabala ML, Carbajal D, Más R, et al. Cholesterol-lowering effects of policosanol in rabbits. Biol Res. 1994;27:205-208.
    • (1994) Biol Res. , vol.27 , pp. 205-208
    • Arruzazabala, M.L.1    Carbajal, D.2    Más, R.3
  • 9
    • 0001853063 scopus 로고
    • Estudio del efecto sobre lípidos y lipoproteínas séricos y de la tolerancia al tratamiento oral con dosis crecientes de policosanol en monos Macaca arctoides
    • Rodríguez C, Mesa R, Más R, et al. Estudio del efecto sobre lípidos y lipoproteínas séricos y de la tolerancia al tratamiento oral con dosis crecientes de policosanol en monos Macaca arctoides. Arch Venezol Farmacol Terap. 1992;11:74-79.
    • (1992) Arch Venezol Farmacol Terap. , vol.11 , pp. 74-79
    • Rodríguez, C.1    Mesa, R.2    Más, R.3
  • 10
    • 0028122593 scopus 로고
    • Study of policosanol oral chronic toxicity in male monkeys (Macaca arctoides)
    • Rodríguez C, Mesa R, Más R, et al. Study of policosanol oral chronic toxicity in male monkeys (Macaca arctoides). Food Chem Toxicol. 1994;32:565-575.
    • (1994) Food Chem Toxicol. , vol.32 , pp. 565-575
    • Rodríguez, C.1    Mesa, R.2    Más, R.3
  • 11
    • 0028144949 scopus 로고
    • Toxicity of policosanol in beagle dogs: One year study
    • Mesa AR, Más R, Noa M, et al. Toxicity of policosanol in beagle dogs: One year study. Toxicol Lett. 1994;73:81-90.
    • (1994) Toxicol Lett. , vol.73 , pp. 81-90
    • Mesa, A.R.1    Más, R.2    Noa, M.3
  • 12
    • 0001801534 scopus 로고
    • Efectos del tratamiento con ateromixol (PPG) (5 mg) en pacientes con hiperlipoproteinemia tipo II
    • Castaño G, Zardoya R, Illnait J, et al. Efectos del tratamiento con ateromixol (PPG) (5 mg) en pacientes con hiperlipoproteinemia tipo II. PCM. 1991;5:21-28.
    • (1991) PCM , vol.5 , pp. 21-28
    • Castaño, G.1    Zardoya, R.2    Illnait, J.3
  • 13
    • 0026670821 scopus 로고
    • Efficacy and safety of policosanol in patients with primary hypercholesterolemia
    • Pons P, Más R, Illnait J, et al. Efficacy and safety of policosanol in patients with primary hypercholesterolemia. Curr Ther Res. 1992;52:507-513.
    • (1992) Curr Ther Res. , vol.52 , pp. 507-513
    • Pons, P.1    Más, R.2    Illnait, J.3
  • 14
    • 0002384735 scopus 로고
    • Estudio comparativo doble ciego de la eficacia y tolerancia del policosanol vs bezafibrato en pacientes con hiperlipidemias tipo II
    • Soltero I, Fuenmayor I, Colmenares J. Estudio comparativo doble ciego de la eficacia y tolerancia del policosanol vs bezafibrato en pacientes con hiperlipidemias tipo II. Arch Venezol Farmacol Terap. 1993;12:71-76.
    • (1993) Arch Venezol Farmacol Terap. , vol.12 , pp. 71-76
    • Soltero, I.1    Fuenmayor, I.2    Colmenares, J.3
  • 15
    • 0028227198 scopus 로고
    • Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment
    • Pons P, Rodríguez M, Robaina C, et al. Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment. J Clin Pharmacol Res. 1994;14:27-33.
    • (1994) J Clin Pharmacol Res. , vol.14 , pp. 27-33
    • Pons, P.1    Rodríguez, M.2    Robaina, C.3
  • 16
    • 0028963194 scopus 로고
    • Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia
    • Aneiros E, Más R, Calderón B, et al. Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia. Curr Ther Res. 1995;56:176-182.
    • (1995) Curr Ther Res. , vol.56 , pp. 176-182
    • Aneiros, E.1    Más, R.2    Calderón, B.3
  • 17
    • 0028931289 scopus 로고
    • One-year study of the efficacy and safety of policosanol (5 mg twice daily) in the treatment of type II hypercholesterolemia
    • Castaño G, Más R, Nodarse M, et al. One-year study of the efficacy and safety of policosanol (5 mg twice daily) in the treatment of type II hypercholesterolemia. Curr Ther Res. 1995;56:296-304.
    • (1995) Curr Ther Res. , vol.56 , pp. 296-304
    • Castaño, G.1    Más, R.2    Nodarse, M.3
  • 18
    • 0029155739 scopus 로고
    • Efficacy and tolerability of policosanol in elderly patients with type II hypercholesterolemia: A 12 month study
    • Castaño G, Canetti M, Morera M, et al. Efficacy and tolerability of policosanol in elderly patients with type II hypercholesterolemia: A 12 month study. Curr Ther Res. 1995;56: 819-828.
    • (1995) Curr Ther Res. , vol.56 , pp. 819-828
    • Castaño, G.1    Canetti, M.2    Morera, M.3
  • 19
    • 0029083862 scopus 로고
    • One year study on the effect of policosanol (5 mg-twice-a-day) on lipid profile in patients with type II hypercholesterolemia
    • Canetti M, Morera M, Illnait J, et al. One year study on the effect of policosanol (5 mg-twice-a-day) on lipid profile in patients with type II hypercholesterolemia. Adv Ther. 1995;12:245-254.
    • (1995) Adv Ther. , vol.12 , pp. 245-254
    • Canetti, M.1    Morera, M.2    Illnait, J.3
  • 20
    • 0029589212 scopus 로고
    • A two year study on the efficacy and tolerability of policosanol in patients with type II hypercholesterolemia
    • Canetti M, Morera M, Illnait J, et al. A two year study on the efficacy and tolerability of policosanol in patients with type II hypercholesterolemia. Int J Clin Pharmacol Res. 1995;15;159-165.
    • (1995) Int J Clin Pharmacol Res. , vol.15 , pp. 159-165
    • Canetti, M.1    Morera, M.2    Illnait, J.3
  • 21
    • 0029945522 scopus 로고    scopus 로고
    • Effects of policosanol on hypercholesterolemic patients with disturbances on serum biochemical indicators of hepatic function
    • Zardoya R, Tula L, Castaño G, et al. Effects of policosanol on hypercholesterolemic patients with disturbances on serum biochemical indicators of hepatic function. Curr Ther Res. 1996;57:568-577.
    • (1996) Curr Ther Res. , vol.57 , pp. 568-577
    • Zardoya, R.1    Tula, L.2    Castaño, G.3
  • 22
    • 0029829726 scopus 로고    scopus 로고
    • Effects of policosanol in hypertensive patients with type II hypercholesterolemia
    • Castaño G, Tula L, Canetti M, et al. Effects of policosanol in hypertensive patients with type II hypercholesterolemia. Curr Ther Res. 1996;57:691-699.
    • (1996) Curr Ther Res. , vol.57 , pp. 691-699
    • Castaño, G.1    Tula, L.2    Canetti, M.3
  • 23
    • 0001452846 scopus 로고    scopus 로고
    • Eficacia, seguridad y tolerabilidad del policosanol en pacientes argentinos con hipercolesterolemia tipo II. Estudio abierto
    • Campilongo R, Sandini P, Feldman R, et al. Eficacia, seguridad y tolerabilidad del policosanol en pacientes argentinos con hipercolesterolemia tipo II. Estudio abierto. Prensa Med Argent. 1996;83:665-672.
    • (1996) Prensa Med Argent. , vol.83 , pp. 665-672
    • Campilongo, R.1    Sandini, P.2    Feldman, R.3
  • 24
    • 0031019054 scopus 로고    scopus 로고
    • A comparative study of policosanol versus probucol in patients with hypercholesterolemia
    • Pons P, Illnait J, Más R, et al. A comparative study of policosanol versus probucol in patients with hypercholesterolemia. Curr Ther Res. 1997;58:26-35.
    • (1997) Curr Ther Res. , vol.58 , pp. 26-35
    • Pons, P.1    Illnait, J.2    Más, R.3
  • 25
    • 0030889985 scopus 로고    scopus 로고
    • Comparative effects of two once-daily regimens of policosanol in patients with type II hypercholesterolemia
    • Castaño G, Más R, Fernández JC, Illnait J. Comparative effects of two once-daily regimens of policosanol in patients with type II hypercholesterolemia. Curr Ther Res. 1997; 58:154-162.
    • (1997) Curr Ther Res. , vol.58 , pp. 154-162
    • Castaño, G.1    Más, R.2    Fernández, J.C.3    Illnait, J.4
  • 26
    • 0031406655 scopus 로고    scopus 로고
    • Effects of policosanol on primary hypercholesterolemia: A 3-year open follow-up
    • Canetti M, Morera MS, Más R, et al. Effects of policosanol on primary hypercholesterolemia: A 3-year open follow-up. Curr Ther Res. 1997;58:868-875.
    • (1997) Curr Ther Res. , vol.58 , pp. 868-875
    • Canetti, M.1    Morera, M.S.2    Más, R.3
  • 27
    • 0031406593 scopus 로고    scopus 로고
    • A comparative study of policosanol versus simvastatin in patients with type II hypercholesterolemia
    • Benítez M, Romero C, Más R, et al. A comparative study of policosanol versus simvastatin in patients with type II hypercholesterolemia. Curr Ther Res. 1997;58:859-867.
    • (1997) Curr Ther Res. , vol.58 , pp. 859-867
    • Benítez, M.1    Romero, C.2    Más, R.3
  • 28
    • 0030857721 scopus 로고    scopus 로고
    • A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia
    • Ortensi G, Gladstein H, Valli H, Tesone PA. A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia. Curr Ther Res. 1997;58:390-401.
    • (1997) Curr Ther Res. , vol.58 , pp. 390-401
    • Ortensi, G.1    Gladstein, H.2    Valli, H.3    Tesone, P.A.4
  • 29
    • 0028897637 scopus 로고
    • Treatment of hypercholesterolemia in NIDDM with policosanol
    • Torres O, Agramonte AJ, Illnait J, et al. Treatment of hypercholesterolemia in NIDDM with policosanol. Diabetes Care. 1995;18:393-397.
    • (1995) Diabetes Care , vol.18 , pp. 393-397
    • Torres, O.1    Agramonte, A.J.2    Illnait, J.3
  • 30
    • 0031018756 scopus 로고    scopus 로고
    • Effect of policosanol on patients with non-insulin-dependent diabetes mellitus (NIDDM) and hypercholesterolemia
    • Crespo N, Alvarez R, Más R, et al. Effect of policosanol on patients with non-insulin-dependent diabetes mellitus (NIDDM) and hypercholesterolemia. Curr Ther Res. 1997; 58:44-51.
    • (1997) Curr Ther Res. , vol.58 , pp. 44-51
    • Crespo, N.1    Alvarez, R.2    Más, R.3
  • 32
    • 0027413130 scopus 로고
    • Effects of policosanol on platelet aggregation in rats
    • Arruzazabala ML, Carbajal D, Más R, et al. Effects of policosanol on platelet aggregation in rats. Thromb Res. 1992;69:321-327.
    • (1992) Thromb Res. , vol.69 , pp. 321-327
    • Arruzazabala, M.L.1    Carbajal, D.2    Más, R.3
  • 33
    • 0030512730 scopus 로고    scopus 로고
    • Effect of policosanol on platelet aggregation in healthy volunteers
    • Valdés S, Arruzazabala ML, Carbajal D, et al. Effect of policosanol on platelet aggregation in healthy volunteers. Int J Clin Pharmacol Res. 1996; 14:67-72.
    • (1996) Int J Clin Pharmacol Res. , vol.14 , pp. 67-72
    • Valdés, S.1    Arruzazabala, M.L.2    Carbajal, D.3
  • 34
    • 0030295032 scopus 로고    scopus 로고
    • Effect of policosanol successive dose increase on platelet aggregation in healthy volunteers
    • Arruzazabala ML, Valdés S, Más R, et al. Effect of policosanol successive dose increase on platelet aggregation in healthy volunteers. Pharmacol Res. 1996;34:181-185.
    • (1996) Pharmacol Res. , vol.34 , pp. 181-185
    • Arruzazabala, M.L.1    Valdés, S.2    Más, R.3
  • 35
    • 0002429418 scopus 로고    scopus 로고
    • Efecto del policosanol sobre la función de las plaquetas en voluntarios sanos
    • Scazziota A, Altman R. Efecto del policosanol sobre la función de las plaquetas en voluntarios sanos. Rev Iberoamer Trombosis Hemostasia. 1996;9:58-62.
    • (1996) Rev Iberoamer Trombosis Hemostasia , vol.9 , pp. 58-62
    • Scazziota, A.1    Altman, R.2
  • 36
    • 85030345747 scopus 로고    scopus 로고
    • Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers
    • In press
    • Arruzazabala ML, Valdés S, Más R, et al. Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol Res. In press.
    • Pharmacol Res.
    • Arruzazabala, M.L.1    Valdés, S.2    Más, R.3
  • 37
    • 0026341760 scopus 로고
    • Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolemia
    • Mölgaard J, Lundh BJ, Von Schenck H, et al. Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolemia. Atherosclerosis. 1991;91(Suppl):S21-S28.
    • (1991) Atherosclerosis , vol.91 , Issue.SUPPL.
    • Mölgaard, J.1    Lundh, B.J.2    Von Schenck, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.