Structure-function relationships of phenylalanine hydroxylase revealed by radiation target analysis

Archives of Biochemistry and Biophysics

Volumn 325, Issue 2, 1996, Pages 235-241

  Davis, Michael D ^a   Parniak, Michael A ^c   Kaufman, Seymour ^a   Kempner, Ellis ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

phenylalanine hydroxylase; protein oligomer; radiation damage; tetrahydrobiopterin

Indexed keywords

PHENYLALANINE 4 MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME PURIFICATION; ENZYME SUBUNIT; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RAT; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0030057695     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0029     Document Type: Article

References (32)

1. Kaufman, S., and Fisher, D. B. (1974) in Molecular Mechanisms of Oxygen Activation (Hayaishi, O., Ed.), pp. 285-369, Academic Press, New York.
2. Shiman, R. (1985) in Folates and Pterins. Volume 2: Chemistry and Biochemistry of Pterins (Blakely, R. L., and Benkovic, S. J., Eds.), pp. 179-249, Wiley, New York.
3. Kaufman, S. (1993) Adv. Enzymol. 67, 77-264.
4. Dahl, H. H. M., and Mercer, J. F. B. (1986) J. Biol. Chem. 261, 4148-4153.
5. Abita, J.-P., Parniak, M. A., and Kaufman, S. (1984) J. Biol. Chem. 259, 14560-14566.
6. Fisher, D. B., and Kaufman, S. (1973) J. Biol. Chem. 248, 4345-4353.
7. Parniak, M. A., Davis, M. D., and Kaufman, S. (1988) J. Biol. Chem. 263, 1223-1230.
8. Parniak, M. A., and Kaufman, S. (1981) J. Biol. Chem. 256, 6876-6882.
9. Donlon, J., and Kaufman, S. (1978) J. Biol. Chem. 253, 6657-6659.
10. Shiman, R., Mortimore, G. E., Schworer, C. M., and Gray, D. W. (1982) J. Biol. Chem. 257, 11213-11216.
11. Tipper, J., and Kaufman, S. (1992) J. Biol. Chem. 267, 889-896.
12. Iwaki, M., Phillips, R. S., and Kaufman, S. (1986) J. Biol. Chem. 261, 2051-2056.
13. Parniak, M. A. (1987) in Unconjugated Pterins and Related Biogenic Amines (Curtius, H.-Ch., and Blau, N., Eds.), pp. 327-337, de Gruyter, Berlin.
14. Kempner, E. S., and Fleischer, S. (1988) Methods Enzymol. 172, 410-439.
15. Kempner, E. S. (1993) Trends Biochem. Sci. 18, 236-239.
16. Kaufman, S. (1987) Methods Enzymol. 142, 3-17.
17. Kempner, E. S., and Miller, J. H. (1994) Anal. Biochem. 216, 451-455.
18. Eichler, D. C., Solomonson, L. P., Barber, M. J., McCreery, M. J., and Ness, G. C. (1987) J. Biol. Chem. 262, 9433-9436.
19. Harmon, J. T., Neilsen, T. B., and Kempner, E. S. (1985) Methods Enzymol. 117, 65-94.
20. Segel, I. (1975) Enzyme Kinetics, Wiley, New York.
21. Laemmli, U. K. (1970) Nature 227, 680-685.
22. Haigler, H. T., Woodbury, D. J., and Kempner, E. S. (1985) Proc. Natl. Acad. Sci. USA 82, 5357-5359.
23. Kaufman, S., Hasegawa, H., Wilgus, H., and Parniak, M. (1981) Cold Spring Harbor Conf. Cell Proliferation 8, 1391-1406.
24. Dhondt, J.-L., Kapatos, G., Parniak, M. A., Wilgus, H., and Kaufman, S. (1982) Biochem. Biophys. Res. Commun. 106, 786-793.
25. Hasegawa, H., and Kaufman, S. (1982) J. Biol. Chem. 257, 3084-3089.
26. Phillips, R. S., and Kaufman, S. (1983) Trans. N.Y. Acad. Sci. 41, 87-95.
27. Fisher, D. B., and Kaufman, S. (1972) J. Biol. Chem. 247, 2250-2252.
28. Potier, M., Thauvette, L., Michaud, L., Giroux, S., and Beauregard, G. (1991) Biochemistry 30, 8151-8157.
29. Kincaid, R. L., Kempner, E., Manganiello, V. C., Osborne, J. C., Jr., and Vaughn, M. (1981) J. Biol. Chem. 256, 11351-11355.
30. Phillips, R. S., Parniak, M. A., and Kaufman, S. (1984) Biochemistry 23, 3836-3842.
31. Shiman, R., Xia, T., Hill, M. A., and Gray, D. W. (1994). J. Biol. Chem. 269, 24647-24656.
32. Xia, T., Gray, D. W., and Shiman, R. (1994) J. Biol. Chem. 269, 24657-24665.