The BRCA2 transactivation domain does not interact with JNK

Genes Chromosomes and Cancer

Volumn 25, Issue 4, 1999, Pages 407-409

  May, Gerhard H W ^a   Harris, Fiona ^a   Gillespie, David ^a   Black, Donald M ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

STRESS ACTIVATED PROTEIN KINASE;

AMINO TERMINAL SEQUENCE; ARTICLE; DNA BINDING; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION REGULATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

EID: 0032771999     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199908)25:4<407::AID-GCC16>3.0.CO;2-I     Document Type: Article

References (13)

1. Bartel P, Chien CT, Sternglanz R, Fields S. 1993. Elimination of false positives that arise in using the two-hybrid system. Biotechniques 14:920-924.
2. Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, Davis RJ. 1996. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 15:2760-2770.
3. Hibi M, Lin A, Smeal T, Minden A, Karin M. 1993. Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the JUN activation domain. Genes Dev 7:2135-2148.
4. Kallunki T, Deng T, Hibi M, Karin M. 1996. JUN can recruit JNK to phosphorylate dimerisation partners via specific docking interactions. Cell 87:929-939.
5. Kilbey A. Black EJ, Unlu M, Gillespie DA. 1996. The v-Jun oncoprotein replaces p39 JUN as the predominant AP-1 constituent in ASV17-transformed fibroblasts: implications for SAPK/ JNK-mediated signal transduction. Oncogene 12:2409-2418.
6. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad, MF, Avruch J, Woodgett JR. 1994. The stress-activated protein kinase subfamily of JUN kinases. Nature 369:156-160.
7. May GH, Funk M, Black EJ, Clark W, Hussain S, Woodgett JR, Gillespie DA. 1998. An oncogenic mutation uncouples the v-Jun oncoprotein from positive regulation by the stress-activated SAPK/ JNK pathway in vivo. Curr Biol 8:117-120.
8. Milner J, Ponder B, Hughes-Davies L, Seltmann M, Kouzarides T. 1997. Transcriptional activation functions in BRCA2. Nature 386:772-377.
9. Nehme A, Baskaran R, Aebi S, Fink D, Nebel S, Cenni B, Wang JY, Howell SB, Christen RD. 1997. Differential induction of JUN NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin. Cancer Res 57:3253-3257.
10. Potapova O, Haghighi A, Bost F, Liu C, Birrer MJ, Gjerset R, Mercola D. 1997. The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitises cells to cisplatin. J Biol Chem 272:14041-14044.
11. Sharan SK, Morimatsu M, Albrecht U, Lim DS, Regel E, Dinh C, Sands A, Eichele G, Hasty P, Bradley A. 1997. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 386:804-810.
12. Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, Thorlacius S, Offit K, Stoppa-Lyonnet D, Belanger C, Bell R, Berry S, Bogden R, Chen Q, Davis T, Dumont M, Frye C, Hattier T, Jammulapati S, Janecki T, Jiang P, Kehrer R, Leblanc JF, Mitchell JT, McArthur-Morrison J, Nguyen K, Peng Y, Samson C, Schroeder M, Snyder SC, Steele L, Stringfellow M, Stroup C, Swedlund B, Swensen J, Teng D, Thomas A, Tran T, Tran T, Tranchant M, Weaver-Feldhaus J, Wong AKC, Shizuya H, Eyfjord JE, Cannon-Albright L, Labrie F, Skolnick MH, Weber B, Kamb A, Goldgar DE. 1996. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet 12:333-337.
13. Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Kyriakis JM, Haimovitz-Friedman A, Fuks Z, Kolesnick RN. 1996. Requirement for ceramide-initiated SAPK/ JNK signalling in stress-induced apoptosis. Nature 380:75-79.