Myb-transformed hematopoietic cells as a model for monocyte differentiation into dendritic cells and macrophages

Journal of Leukocyte Biology

Volumn 66, Issue 2, 1999, Pages 217-223

  Banyer, Joanne L ^a   Hapel, Andrew J ^a  

^a Biology and Environment   (Australia)

Author keywords

Cytokines; Development; Gene expression; Myeloid cells

Indexed keywords

CD40 ANTIGEN; COMPLEMENTARY DNA; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTATION; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CYTOKINE PRODUCTION; DENDRITIC CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; T LYMPHOCYTE;

EID: 0032769709     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.2.217     Document Type: Article

References (82)

1. Abbas, A .K., Murphy, K. M., Sher, A. (1996) Functional diversity of helper T lymphocytes. Nature 383, 787-793.
2. Sprent, J., Schaefer, M. (1989) Antigen-presenting cells for unprimed T cells. Immunol. Today 10, 17-23.
3. Hapel, A. J., McColl, S. R. (1996) Cytokines in immunology. Principles of Medical Biology, Chapt. 9, JAI Press Inc., 151-169
4. Larsen, C. P., Ritchie, S. C., Hendrix, R., Linsley, P. S., Hathcock, K. S., Hodes, R. J., Lowry, R. P., Pearson, T. C. (1994) Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. J. Immunol. 152, 5208-5219.
5. Chang, C. H., Furue, M., Tamaki, K. (1995) B7-1 expression of Langerhans cells is up-regulated by pro-inflammatory cytokines, and is down-regulated by interferon-gamma or by interleukin-10. Eur. J. Immunol.25, 394-398.
6. Shimada, S., Caughman, S. W., Sharrow, S. O., Stephany, D., Katz, S. I. (1987) Enhanced antigen-presenting capacity of cultured Langerhans' cells is associated with markedly increased expression of Ia antigen. J. Immunol. 139, 2551-2555.
7. Sallusto, F., Cella, M., Danieli, C., Lanzavecchia, A. (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: down-regulation by cytokines and bacterial products. J. Exp. Med. 182, 389-400.
8. Caux, C., Vanbervliet, B., Massacrier, C., Azuma, M., Okumura, K., Lanier, L. L., Banchereau, J. (1994)B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J. Exp. Med. 180, 1841-1847.
9. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I., Banchereau, J. (1994) Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180, 1263-1272.
10. Inaba, K., Witmer-Pack, M., Inaba, M., Hathcock, K. S., Sakuta, H., Azuma, M., Yagita, H., Okumura, K., Linsley, P. S., Ikehara, S., Muramatsu, S., Hodes, R. J., Steinman, R. M. (1994) The tissue distribution of the B7-2 co-stimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J. Exp. Med.180, 1849-1860.
11. Banchereau, J., Steinman, R. M. (1998) Dendritic cells and the control of immunity. Nature 392, 245-392.
12. Mackey, M. F., Barth, R. J., Noelle, R. J. (1998) The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. J. Leukoc. Biol. 63, 418-428.
13. Lichtman, A. H., Abbas, A. K. (1997) T-cell subsets: recruiting the right kind of help. Curr. Biol. 7, R242-R244.
14. Cella, M., Sallusto, F., Lanzavecchia, A. (1997) Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 9, 10-16.
15. Austyn, J. M., Gordon, S. (1981) F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11, 805-815.
16. Roth, P., Stanley, E. R. (1992) The biology of CSF-1 and its receptor. Curr. Top. Microbiol. Immunol. 181, 141-167.
17. Chegini, N. (1997) The role of growth factors in peritoneal healing: transforming growth factor beta (TGF-beta) Eur. J. Surg. (Suppl.) 577, 17-23.
18. Holt, P. G., Oliver, J., Bilyk, N., McMenamin, C., McMenamin, P. G., Kraal, G., Thepen T. (1993) Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J. Exp. Med. 177, 397-407.
19. Watts, C. (1997) Immunology. Inside the gearbox of the dendritic cell. Nature 388, 724-725.
20. Lukas, M., Stossel, H., Hefel, L., Imamura, S., Fritsch, P., Sepp, N. T., Schuler, G., Romani, N. (1996) Human cutaneous dendritic cells migrate through dermal lymphatic vessels in a skin organ culture model. J. Invest. Dermatol. 106, 1293-1299.
21. De Smedt, T., Pajak, B., Muraille, E., Lespagnard, L., Heinen, E., De Baetselier, P., Urbain, J., Leo, O., Moser, M. (1996) Regulation of dendritic cell numbers and maturation hy lipopolysaccharide in vivo. J. Exp. Med. 184, 1413-1424.
22. Sallusto, F., Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179, 1109-1118.
23. Winzler, C., Rovere, P., Rescigno, M., Granucci, F., Penna, G., Adorini, L., Zimmermann, V. S., Davoust, J., Ricciardi-Castagnoli, P. (1997) Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 185, 317-328.
24. Nijman, H. W., Kleijmeer, M. J., Ossevoort, M. A., Oorschot, V. M., Vierboom, M. P., van de Keur, M., Kenemans, P., Kast, W. M., Geuze, H. J., Melief, C. J. (1995) Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J. Exp. Med. 182, 163-174.
25. Pierre, P., Turley, S. J., Gatti, E., Hull, M., Meltzer, J., Mirza, A., Inaba, K., Steinman, R. M., Mellman, I. (1997) Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388, 787-792.
26. Cella, M., Engering, A., Pinet, V., Pieters, J., Lanzavecchia, A. (1997) Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782-787.
27. Maraskovsky, E., Pulendran, B., Shortman, K. (1999) Lymphoid-related dendritic cells. In Dendritic Cells (M. T. Lotze and A. W. Thompson, eds.) New York: Academic Press, 93-107.
28. + dendritic cells (DC) veto cells? The role of CD8 on DC in DC development and in the regulation of CD4 and CD8 T cell responses. Int. Immunol. 9, 1061-1064.
29. Suss, G., Shortman, K. (1996) A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis. J. Exp. Med. 183, 1789-1796.
30. Peters, J. H., Gieseler, R., Thiele, B., Steinbach, F. (1996) Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. Immunol. Today 17, 273-276.
31. Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., Steinman, R. M. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176, 1693-1702.
32. Heufler, C., Koch, F., Schuler, G. (1988) Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells. J. Exp. Med. 167, 700-705.
33. + murine hematopoietic progenitor cells. Blood 90, 4842-4853.
34. Peters, J. H., Xu, H., Ruppert, J., Ostermeier, D., Friedrichs, D., Gieseler, R. K. (1993) Signals required for differentiating dendritic cells from human monocytes in vitro. Adv. Exp. Med. Biol. 329, 275-280.
35. Ruppert, J., Schutt, C., Ostermeier, D., Peters, J. H. (1993) Down-regulation and release of CD14 on human monocytes by IL-4 depends on the presence of serum or GM-CSF. Adv. Exp. Med. Biol. 329, 281-286.
36. Steinbach, F., Krause, B., Thiele, B. (1995) Monocyte derived dendritic cells (MODC) present phenotype and functional activities of Langerhans cells/dendritic cells. Adv. Exp. Med. Biol. 378, 151-153.
37. Romani, N., Gruner, S., Brang, D., Kampgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P. O., Steinman, R. M., Schuler, G. (1994) Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180, 83-93.
38. Xu, H., Kramer, M., Spengler, H. P., Peters, J. H. (1995) Dendritic cells differentiated from human monocytes through a combination of IL-4, GM-CSF and IFN-gamma exhibit phenotype and function of blood dendritic cells. Adv. Exp. Med. Biol. 378, 75-78.
39. Caux, C., Dezutter-Dambuyant, C., Schmitt, D., Banchereau, J. (1992) GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Nature 360, 258-261.
40. Witsell, A. L., Schook, L. B. (1991) Macrophage heterogeneity occurs through a developmental mechanism. Proc. Natl. Acad. Sci. USA 88, 1963-1967.
41. Rutherford, M. S., Witsell, A., Schook, L. B. (1993) Mechanisms generating functionally heterogeneous macrophages: chaos revisited. J. Leukoc. Biol. 53, 602-618.
42. Rutherford, M. S, and Schook, L. B. (1992) Differential immunocompetence of macrophages derived using macrophage or granulocyte-macrophage colony-stimulating factor. J. Leukoc. Biol. 51, 69-76.
43. + progenitors in human bone marrow. J. Immunol. 149, 2681-2688.
44. Inaba, K., Inaba, M., Deguchi, M., Hagi, K., Yasumizu, R., Ikehara, S., Muramatsu, S., Steinman, R. M. (1993) Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. Proc. Natl. Acad. Sci. USA 90, 3038-3042.
45. Boehmelt, G., Madruga, J., Dorller, P., Briegel, K., Schwarz, H., Enrietto, P. J., Zenke, M. (1995) Dendritic cell progenitor is transformed by a conditional v-Rel estrogen reteptor fusion protein V-RelER. Cell 80, 341-352.
46. Santiago-Schwarz, F., Belilos, E., Diamond, B., Carsons, S. E. (1992) TNF in combination with GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages. J. Leukoc. Biol. 52, 274-281.
47. Inaba, K., Steinman, R. M., Pack, M. W., Aya, H., Inaba, M., Sudo, T., Wolpe, S., Schuler, G. (1992) Identification of proliferating dendritic cell precursors in mouse blood. J. Exp. Med. 175, 1157-1167.
48. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF TNF alpha. J. Exp. Med. 184, 695-706.
49. Strunk, D., Egger, C., Leitner, G., Hanau, D., Stingl, G. (1997) A skin homing molecule defines the Langerhans cell progenitor in human peripheral blood. J. Exp. Med. 185, 1131-1136.
50. Kashihara, M., Ueda, M., Horiguchi, Y., Furukawa, F., Hanaoka, M., Imamura, S. (1986) A monoclonal antibody specifically reactive to human Langerhans cells. J. Invest. Dermatol. 87, 602-607.
51. Tang, A., Amagai, M., Granger, L. G., Stanley, J. R., Udey, M. C. (1993) Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin. Nature 361, 82-85.
52. Steinman, R. M., Pack, M., Inaba, K. (1997) Dendritic cells in the T-cell areas of lymphoid organs. Immunol. Rev. 156, 25-37.
53. Ito, T., Inaba, M., Inaba, K., Toki, J., Sogo, S., Iguchi, T., Uehira, K., Amakawa, R., Fukuhara, S., Ikehara, S. (1998) Distinctive subsets of dendritic cells in human peripheral blood. J. Leukoc. Biol. (Suppl. 2), A10, 19.
54. Goordyal, P., Isaacson, P. G. (1985) Immunocytochemical characterization of monocyte colonies of human bone marrow: a clue to the origin of Langerhans cells and interdigitating reticulum cells. J. Pathol. 146, 189-195.
55. de Fraissinette, A., Schmitt, D., Dezutter-Dambuyant, C., Guyotat, D., Zabol, M. T., Thivolet, J. (1988) Culture of putative Langerhans cell bone marrow precursors: characterization of their phenotype. Exp. Hematol. 16, 764-768.
56. Burkly, L., Hession, C., Ogata, L., Reilly, C., Marconi, L. A., Olson, D., Tizard, R., Cate, R., Lo, D. (1995) Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373, 531-536.
57. Szabolcs, P., Avigan, D., Gezelter, S., Ciocon, D. H., Moore, M. A., Steinman, R. M., Young, J. W. (1996) Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate. Blood 87, 4520-4530.
58. Metcalf, D. (1997) Murine hematopoietic stem cells committed to macrophage/dendritic cell formation: stimulation by Flk2-ligand with enhancement by regulators using the gp130 receptor chain. Proc. Natl. Acad. Sci. USA 94, 11552-1556.
59. +) cells immunocompetent committed precursors of macrophages and dendritic cells. Blood 91, 3892-3900.
60. Hausser, G., Ludewig, B., Gelderblom, H. R., Tsunetsugu-Yokota, Y., Akagawa, K., Meyerhans, A. (1997) Monocyte-derived dendritic cells represent a transient stage of differentiation in the myeloid lineage. Immunobiol. 197, 534-542.
61. Goerdt, S., Kodelja, V., Schmuth, M., Orfanos, C. E., Sorg, C. (1996) The mononuclear phagocyte-dendritic cell dichotomy: myths, facts, and a revised concept. Clin. Exp. Immunol. 105, 1-9.
62. Rossi, G., Heveker, N., Thiele, B., Gelderblom, H., Steinbach, F. (1992) Development of a Langerhans cell phenotype from peripheral blood monocytes. Immunol. Lett. 31, 189-197.
63. Murphy, G. F., Messadi, D., Fonferko, E., Hancock, W. W. (1986) Phenotypic transformation of macrophages to Langerhans cells in the skin. Am. J. Pathol. 123, 401-406.
64. Peters, J. H., Ruhl, S., Friedrichs, D. (1987) Veiled accessory cells deduced from monocytes. Immunobiol. 176, 154-166.
65. Bartelmez, S., Bradley, T. R., Bertoncello, I., Tushinski, R. J., Mochizuki, D., Stanley, E. R., Hapel, A. J., Young, I. G., Kriegler, A. B. and Hodgson, G. S. (1988) Interleukin-1 plus CSF-1 and IL-3 are essential for clonal proliferation of primitive myeloid bone marrow cells. Exp. Haematol. 17, 240-248.
66. Ardavin, C., Wu, L., Li, C. L., Shortman, K. (1993) Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 362, 761-763.
67. Wu, L., Li, C. L., Shortman, K. (1996) Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny. J. Exp. Med. 184, 903-911.
68. Bender, A., Sapp, M., Schuler, G., Steinman, R. M., Bhardwaj, N. (1996) Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J. Immunol. Meth. 196, 121-135.
69. Romani, N., Reider, D., Heuer, M., Ebner, S., Kampgen, E., Eibl, B., Niederwieser, D., Schuler, G. (1996) Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J. Immunol. Meth. 196, 137-151.
70. Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M., Muller, W. A. (1998) Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 282, 480-483.
71. Gonda, T. J., Macmillan, E. M., Townsend, P. V., Hapel, A. J. (1993). Differentiation state and responses haemopoietic growth factors of murine myeloid cells transformed by myb. Blood 82, 2813-2822.
72. Ramsay, R. G., Ishii, S., Gonda, T. J. (1991) Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb. Oncogene 6, 1875-1879.
73. O'Connell, P. J. (1996) Cytokine Regulated Differentiation and Apoptosis of Myb-Transformed Cell Lines. The Australian National University, ACT, Australia, Ph.D. thesis.
74. Mak, N-K., Fung, M.-C., Leung, K-N., Hapel, A. J. (1993) Monocytic differentiation of a myelomonocytic leukaemic cell (WEHI 3B JCS) is induced by alpha-tumour necrosis factor (TNF-α). Cell. Immunol. 150, 1-14.
75. Leung, K-L., Mak, K. Fung, M-C., Hapel, A. J. (1994) Synergistic effect of L-4 and TNF-α in the induction of monocytic differentiation of a mouse myeloid leukaemic cell line (WEHI-3B JCS). Immunol. 81, 65-72.
76. Takeuchi, M., Alard, P., Streilein, J. W. (1998) TGF-beta promotes immune deviation by altering accessory signals of antigen-presenting cells. J. Immunol. 160, 1589-1597.
77. Toossi, Z., Mincek, M., Seeholtzer, E., Fulton, S. A., Hamilton, B. D., Hirsch, C. S. (1997) Modulation of IL-12 by transforming growth factor-beta (TGF-beta) in Mycobacterium tuberculosis-infected mononuclear phagocytes and in patients with active tuberculosis. J. Clin. Lab. Immunol. 49, 59-75.
78. Gorham, J. D., Guler, M. L., Fenoglio, D., Gubler, U., Murphy, K. M. (1998) Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells. J. Immunol. 161, 1664-1670.
79. Bright, J. J., Sriram, S. (1998) TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes. J. Immunol. 161, 1772-1777.
80. Orlofsky, A., Lin, E. Y., Prystowsky, M. B. (1994) Selective induction of the beta chemokine C10 by IL-4 in mouse macrophages. J. Immunol. 152, 5084-5091.
81. Ramshaw, I. A., Ramsay, A. J., Karupiah, G., Rolph, M. S., Mahalingam, S., Ruby, J. C. (1997) Cytokines and immunity to viral infections. Immunol. Rev. 159, 119-135.
82. Cole, K. E., Strick, C. A., Paradis, T. J., Ogborne, K. T., Loetscher, M., Gladue, R. P., Lin, W., Boyd, J. G., Moser, B., Wood, D. E., Sahagan, B. G., Neote, K. (1998) Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 187, 2009-2021.