The protein kinase inhibitor 1-(5-isoquinolinylsulfonyl)-2- methylpiperzine (H-7) prevents and reverses Ca2+-mediated injury in isolated rat hepatocyte couplets

Toxicology and Applied Pharmacology

Volumn 161, Issue 2, 1999, Pages 192-201

  Roma, Marcelo G ^a   Ahmed Choudhury, Jalal ^a   Coleman, Roger ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

A23187; Actin cytoskeleton; AM; BAPTA; Blebbing; Ca2+ mediated injury; Extracellular ATP; H 7; Isolated rat hepatocytes couplets; Protein kinase C; Tight junctional permeability

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; BILE ACID; CALCIMYCIN; CALCIUM; CALCIUM CHELATING AGENT; CALCIUM IONOPHORE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; F ACTIN; FLUORESCEIN DERIVATIVE; PROTEIN KINASE C INHIBITOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; LIVER CELL DAMAGE; MALE; NONHUMAN; RAT; TIGHT JUNCTION;

ANIMALIA;

EID: 0032761192     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1999.8801     Document Type: Article

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