Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 4 21-4, 1999, Pages

  Li, Dechun ^a   Zhou, Nan ^a   Johns, Roger A ^a,b  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nitric oxide

Indexed keywords

GUANYLATE CYCLASE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HYPOXIA; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; SIGNAL TRANSDUCTION;

EID: 0032754248     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.4.l841     Document Type: Article

References (58)

1. Adnot, S., B. Raffestin, and S. Eddahibi. NO in the lung. Respir. Physlol. 101: 109-120, 1995.
2. Adnot, S., B. Raffestin, S. Eddahibi, C. Defouilloy, and P. Andrivet. Nitric oxide and chronic hypoxic pulmonary hypertension. In: Nitric Oxide and the Lung, edited by W. M. Zapol and K. D. Bloch. New York: Dekker, 1996, p. 137-163.
3. Archer, S., J. Tolins, L. Raij, and E. Weir. Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium-derived relaxing factor. Biochem. Biophys. Res. Commun. 164: 1198-1205, 1989.
4. Archer, S. L., and E. K. Weir. Mechanisms in hypoxic pulmonary hypertension. In: Pulmonary Circulation, edited by C. A. Wagenvoort and H. Denolin. New York: Elsevier, 1989, p. 87-113.
5. Barer, G., C. Emery, A. Stewart, D. Bee, and P. Howard. Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats. J. Physiol. (Lond.) 463: 1-16, 1998.
6. Bina, S., J. L. Hart, Y. Sei, and S. M. Muldoon. Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels. Eur. J. Pharmacol. 351: 253-260, 1998.
7. Bloch, K. D., G. Filippov, L. S. Sanchez, M. Nakane, and A. M. De La Monte. Pulmonary soluble guanylate cyclase, a nitric oxide receptor, is increased during the perinatal period. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L400-L406, 1997.
8. Brendel, J. K., and R. A. Johns. Isoflurane does not vasodilate rat thoracic aortic rings by endothelium-derived relaxing factor or other cyclic GMP-mediated mechanisms. Anesthesiology 77: 126-131, 1992.
9. Brophy, C. M., E. G. Whitney, S. Lamb, and A. Beall. Cellular mechanisms of cyclic nucleotide-induced vasorelaxation. J. Vasc. Surg. 25: 390-397, 1997.
10. Buechler, W. A., M. Nakane, and F. Murad. Expression of soluble guanylate cyclase activity requires both enzyme subunits. Biochem. Biophys. Res. Commun. 174: 351-357, 1991.
11. Cox, K. H., D. V. DeLeon, L. M. Angerer, and R. C. Angerer. Detection of mRNAs in sea urchin embrayos by in situ hybridization using asymmmetric RNA probes. Dev. Biol. 101: 485-502, 1984.
12. Crawley, D. E., L. Zhao, M. A. Giembycz, S. Liu, P. J. Barnes, R. J. D. Winter, and T. W. Evans. Chronic hypoxia impairs soluble guanylyl cyclase mediated pulmonary arterial relaxation in the rat. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L325-L332, 1992.
13. D'Angelis, C., P. A. Nickerson, R. H. Steinhorn, and F. C. Morin III. Heterogeneous distribution of soluble guanylate cyclase in the pulmonary vasculature of the fatal lamb. Anat. Rec. 250: 62-69, 1998.
14. D'Angelis, C., R. H. Steinhorn, A. Tzao, and F. C. Morin III. Soluble guanylate cyclase is decreased within pulmonary arterial smooth muscle of fetal lambs with experimentally-induced pulmonary hypertension (Abstract). Pediatr. Res. 41: 250A, 1997.
15. Dinh-Xuan, A. T. Endothelial modulation of pulmonary vascular tone. Eur. Respir. J. 5: 757-762, 1992.
16. Fike, C. D., M. R. Kaplowitz, J. Thomas, and L. D. Nelin. Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L517-L526, 1998.
17. Fouty, B., P. Komalavilas, M. Muramatsu, A. Cohen, I. F. McMurtry, T. M. Lincoln, and D. M. Rodman. Protein kinase G is not essential to NO-cGMP modulation of basal tone in rat pulmonary circulation. Am. J. Physiol. 274 (Heart Circ. Physiol. 43): H672-H678, 1998.
18. Freas, W., R. Llave, M. Jing, M. Hart, P. McQuillan, and S. M. Muldoon. Contractile effects of diasprin cross-linked hemoglobin (DLHb) on isolated porcine blood vessels. J. Lab. Clin. Med. 125: 762-767, 1995.
19. Garthwaite, J., E. Southam, C. L. Boulton, E. B. Nielsen, K. Schmidt, and B. Mayer. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 48: 184-188, 1995.
20. Giuili, G., U. Scholl, F. Bulle, and G. Guellaen. Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain. FEBS Lett. 304: 83-88, 1992.
21. Hampl, V., S. L. Archer, D. P. Nelson, and E. K. Weir. Chronic EDRF inhibition and hypoxia: Effects on pulmonary circulation and systemic blood pressure. J. Appl. Physiol. 75: 1748-1757, 1993.
22. Harteneck, C., B. Wedel, D. Koesling, J. Malkewitz, E. Bohme, and G. Schultz. Molecular cloning and expression of a new α-subunit of soluble guanylyl cyclase: interchangeability of the α-subunits of the enzyme. FEBS Lett. 292: 217-222, 1991.
23. Hasleton, P. S., D. Heath, and D. B. Brewer. Hypertensive pulmonary vascular disease in states of chronic hyoxia. J. Pathol. Bacteriol. 95: 431-440, 1968.
24. Hislop, A., and L. Reid. New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br. J. Exp. Pathol. 57: 542-554, 1976.
25. Hobbs, A. Soluble guanylate cyclase: the forgotten sibling. Trends Pharmacol. Sci. 18: 484-491, 1997.
26. Hobbs, A., and L. J. Ignarro. The nitric oxide-cyclic GMP signal transduction system. In: Nitric Oxide and the Lung, edited by W. M. Zapol and D. B. Bloch. New York: Dekker, 1996, p. 1-57.
27. Johns, R. A., J. M. Linden, and M. J. Peach. Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia. Circ. Res. 65: 1508-1515, 1989.
28. Jones, R. C., and L. Reid. Vasculture remodeling in clinical and experimental pulmonary hypertensions. In: Pulmonary Vascular Remodeling, edited by J. E. Bishop, J. T. Reeves, and G. J. Laurent. London: Portland, 1995, p. 47-116.
29. Kim, T. D., and J. N. Burstyn. Identification and partial purification of an endogenous inhibitor of soluble guanlyl cyclase from bovine lung. J. Biol. Chem. 269: 15540-15545, 1994.
30. Le Cras, T. D., C. Xue, A. Rengasamy, and R. A. Johns. Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L164-L170, 1996.
31. Li, D., D. Wang, D. A. Griffith-Johnson, T. N. Wells, T. J. Williams, P. J. Jose, and P. K. Jeffery. Eotaxin protein, gene expression in guinea pig lungs: constitutive expression and upregulation after allergen challenge. Eur. Respir. J. 10: 1946-1954, 1997.
32. ca channel activity in coronary artery smooth muscle. Hypertension 31: 303-308, 1998.
33. Martinez-Montero, J., C. S. Herrington, J. Stickland, H. Sawyer, M. Evens, D. M. Flannery, and J. O. McGee. Model system for optimising mRNA non-isotopic in situ hybridization: riboprobe detection of lysozyme mRNA in archival gut biopsy specimens. J. Clin. Pathol. 44: 835-839, 1991.
34. Melton, D. A., P. A. Krieg, and M. A. Rebgliati. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmid containing bacteriophage SP6 promoter. Nucleic Acids Res. 12: 7035-7041, 1984.
35. Meyrick, B., and L. Reid. The effect of continued hypoxia on rat pulmonary arterial circulation. An ultrastructural study. Lab. Invest. 38: 188-200, 1978.
36. Mittal, C. K. Determination of adenylate cyclase and guanylate cyclase activities in cells and immune system. Methods Enzymol. 132: 422-428, 1986.
37. Murad, F., U. Forstermann, M. Nakane, J. Pollock, D. R. Tracey, T. Matsumoto, and W. Buechler. The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular communication. Adv. Second Messenger Phosphoprotein Res. 28: 101-109, 1993.
38. Murad, F., U. Forstermann, M. Nakane, H. H. H. W. Schmidt, J. Pollock, H. Sheng, T. Matsumoto, T. Warner, J. Mitchell, and R. Tracey. The nitric oxide-cyclic GMP signal transduction pathway in vascular smooth muscle preparations and other tissues. Japn. J. Pharmacol. 58, Suppl. 2: 150P-157P, 1992.
39. Naeye, R. L. Hypoxemia and pulmonary hypertension. Arch. Pathol. 71: 447-452, 1961.
40. Nakane, M., and F. Murad. Cloning of guanylyl cyclase isoforms. Adv. Pharmacol. 26: 7-18, 1994.
41. Nakane, M., S. Saheki, T. Kuno, K. Ishii, and F. Murad. Molecular cloning of a cDNA coding for 70 kilodalton subunit of soluble guanylate cyclase from rat lung. Biochem. Biophys. Res. Commun. 157: 1139-1147, 1988.
42. Quinlan, T. R., V. E. Laubach, E. G. Shesel, N. Zhou, and R. A. Johns. NOS 3 deficient mice exhibit a reduced pulmonary vascular remodeling response to chronic hypoxia. J. Histochem. Cytochem. In press.
43. Rabinovitch, M. Insights into the pathogenesis of primary pulmonary hypertension from animal models. In: Primary Pulmonary Hypertension, edited by L. J. Rubin and S. Rich. New York: Dekker, 1996, p. 63-81.
44. Rabinovitch, M. Pulmonary hypertension: updating a mysterious diseas. Cardiovasc. Res. 34: 268-272, 1997.
45. Rabinovitch, M., W. Gamble, A. S. Nadas, O. S. Miettinen, and L. Reid. Rat pulmonary cirulation after chronic hypoxia: hemodynamic and structural features. Am. J. Physiol. 236 (Heart Circ. Physiol. 5): H818-H827, 1979.
46. Resta, T. C. C., R. J. Gonzales, W. G. Dial, T. C. Sanders, and B. R. Walker. Selective upregulation of arterial endothelial nitric oxide synthase in pulmonary hypertension. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H806-H813, 1997.
47. Rudic, R. D., E. G. Shesely, N. Maeda, O. Smithies, S. S. Segal, and W. C. Sessa. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J. Clin. Invest. 101: 731-736, 1998.
48. Schenborn, E. T., and R. C. Mierendorf. A novel transcription property of SP6 and T7 RNA polymerase: dependence on template structure. Nucleic Acids Res. 13: 6226-6230, 1985.
49. Schrammel, A., S. Behrends, K. Schmidt, D. Koesling, and B. Mayer. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol. Pharmacol. 50: 1-5, 1996.
50. Shaul, P. W., A. J. North, T. S. Brannon, K. Ujiie, L. B. Wells, P. A. Nisen, J. Lowenstein, S. H. Snyder, and R. A. Star. Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung. Am. J. Respir. Cell Mol. Biol. 13: 167-174, 1995.
51. Steinhorn, R. H., J. A. Russell, and F. C. Morin III. Disruption of cGMP production in pulmonary arteries isolated from fetal lambs with pulmonary hypertension. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1483-H1489, 1995.
52. Steudel, W., F. Ichinose, P. L. Huang, W. E. Hurford, R. C. Jones, J. A. Bevan, M. C. Fishman, and W. M. Zapol. Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS3) gene. Circ. Res. 81: 34-41, 1997.
53. Steudel, W., M. Scherrer-Crosbie, K. D. Bloch, J. Weimann, R. C. Jones, M. H. Picard, and W. M. Zapol. Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthse 3. J. Clin. Invest. 101: 2468-2477, 1998.
54. Voelkel, N. F., R. M. Tuder, and E. K. Weir. Pathophysiology of primary pulmonary hypertension: from physiology to molecular biology. In: Lung Biology in Health and Disese, edited by C. Lenfant. New York: Dekker, 1996, p. 83-129.
55. Warner, T. D., J. A. Mitchell, H. Sheng, and F. Murad. Effects of cyclic GMP on smooth muscle relaxation. Adv. Pharmacol. 26: 171-193, 1994.
56. Xue, C., and R. A. Johns. Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat. Hypertension 28: 743-753, 1996.
57. Xue, C., A. Rengasamy, T. D. Le Cras, P. Koberna, G. Dailey, and R. A. Johns. Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation by chronic hypoxia. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L667-L678, 1994.
58. Xue, C., P. R. Reynolds, and R. A. Johns. Developmental expression of NOS isoforms in fetal rat lung: implications for transitional circulation and pulmonary angiogenesis. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L88-L100, 1996.