Expression of β-defensin genes by human salivary glands

Oral Microbiology and Immunology

Volumn 14, Issue 6, 1999, Pages 371-374

  Bonass, W A ^a   High, A S ^a   Owen, P J ^a   Devine, Deirdre A ^a,b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS DENTAL INSTITUTE   (United Kingdom)

Author keywords

defensin gene; Expression; Human salivary gland

Indexed keywords

BETA DEFENSIN; GENE EXPRESSION; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND;

DEFENSINS; GENE EXPRESSION; HUMANS; PROTEIN BIOSYNTHESIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SALIVARY GLANDS; SALIVARY PROTEINS; SIALADENITIS;

EID: 0032752577     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-302X.1999.140607.x     Document Type: Article

References (22)

1. Bensch KW, Raida M, Mägert H-J, Schulz-Knappe P, Forssmann W-G. hBD-1: a novel β-defensin from human plasma. FEBS Lett 1995: 368: 331-335.
2. Boman HG. Peptide antibiotics: holy or heretic grails of innate immunity? Scand J Immunol 1996: 43: 475-482.
3. Chertov O, Michiel DF, Xu L, Wang JM, Tani K, Murphy WJ, Longo DL, Taub DD, Oppenheim JJ. Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem 1996: 271: 2935-2940.
4. Ganz T, Lehrer RI. Antimicrobial peptides of vertebrates. Curr Opin Immunol 1998: 10: 41-44.
5. Goldman MJ, Anderson GM, Stolzenberg ED, Kari UP, Zasloff M, Wilson JM. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 1997: 88: 553-560.
6. Harder J, Bartels J, Christophers E, Schroeder J-M. A peptide antibiotic from human skin. Nature 1997: 387: 861-862.
7. Herwig S, Su Q, Zhang W, Ma YS, Tempst P. Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells. Blood 1996: 87: 350-364.
8. Krisanaprakornkit S, Weinberg A, Perez CN, Dale BA. Expression of the peptide antibiotic human β-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infect Immun 1998: 66: 4222-4228.
9. Lamkin MS, Oppenheim FG. Structural features of salivary function. Crit Rev Oral Biol Med 1993: 4: 251-259.
10. Lencer WI, Cheung G, Strohmeier GR, Currie MG, Ouellette AJ, Selsted ME, Madara JL. Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3. Proc Natl Acad Sci U S A 1997: 94: 8585-8589.
11. Liu L, Zhao C, Heng HHQ, Ganz T. The human β-defensin-1 and α-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. Genomics 1997: 43: 316-320.
12. Mahida YR, Rose F, Chan WC. Antimicrobial peptides in the gastrointestinal tract. Gut 1997: 40: 161-163.
13. Martin E, Ganz T, Lehrer RI. Defensins and other endogenous peptide antibiotics of vertebrates. J Leukoc Biol 1995: 58: 128-136.
14. McCray PB, Bentley L. Human airway epithelia express a β-defensin. Am J Respir Cell Mol Biol 1997: 16: 343-349.
15. Ouellette AJ, Selsted ME. Enteric defensins. Curr Opin Gastroenterol 1997: 13: 494-499.
16. Panyutich AV, Hiemstra PS, van Wetering S, Ganz T. Human neutrophil defensin and serpins form complexes and inactivate each other. Am J Respir Cell Mol Biol 1995: 12: 351-357.
17. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning, A laboratory manual. 2nd edn. Cold Spring Harbor: Cold Spring Harbor Press, 1989.
18. Shtivelman E, Lifshitz B, Gale RP, Roe BA, Canaani E. Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. Cell 1986: 47: 277-284.
19. Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB, Ganz T. Human β-defensin-1: an antimicrobial peptide of urogenital tissues. J Clin Invest 1998: 101: 1633-1642.
20. van Wettering S, Mannesse-Lazeroms SPG, van Sterkenburg MAJA, Daha MR, Dijkman JH, Hiemstra PS. Effect of defensins on interleukin-8 synthesis in airway epithelial cells. Lung Cell Mol Physiol 1997: 16: L888-L896.
21. Wolff A, Moreira JE, Bevins CL, Hand AR, Fox PC. Magainin-like immuno-reactivity in human submandibular and labial salivary glands. J Histochem Cytochem 1990: 38: 1531-1534.
22. Zhao C, Wang I, Lehrer RI. Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett 1996: 396: 319-322.