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Volumn 52, Issue 4, 1999, Pages 455-463

Pharmaceutically active secondary metabolites of microorganisms

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPHOTERICIN B; AMPICILLIN; ANTHELMINTIC AGENT; ANTIBIOTIC AGENT; ANTILIPEMIC AGENT; ANTIMIGRAINE AGENT; ANTINEOPLASTIC AGENT; ANTIPARASITIC AGENT; AZITHROMYCIN; BIALAPHOS; CEFACLOR; CEFALEXIN; CEFIXIME; CEFOTAXIME; CEFOXITIN; CEFTRIAXONE; CEFUROXIME; CLINDAMYCIN; CYCLOSPORIN A; ENZYME INHIBITOR; FLOMOXEF; IMMUNOSUPPRESSIVE AGENT; MYCOTOXIN; PACLITAXEL; PENICILLIN G; SULTAMICILLIN; UNINDEXED DRUG;

EID: 0032745552     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530051546     Document Type: Short Survey
Times cited : (360)

References (68)
  • 3
    • 0031088644 scopus 로고    scopus 로고
    • Microbial secondary metabolites play important roles in medicine; Prospects for discovery of new drugs
    • Bentley R (1997) Microbial secondary metabolites play important roles in medicine; prospects for discovery of new drugs. Perspect Biol Med 40: 364-394
    • (1997) Perspect Biol Med , vol.40 , pp. 364-394
    • Bentley, R.1
  • 5
    • 0021798830 scopus 로고
    • Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin
    • Birnbaum J, Kahan FM, Kropp H, MacDonald JS (1985) Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin. Amer J Med 78 Suppl.6A: 3-21
    • (1985) Amer J Med , vol.78 , Issue.SUPPL. 6A , pp. 3-21
    • Birnbaum, J.1    Kahan, F.M.2    Kropp, H.3    Macdonald, J.S.4
  • 7
    • 0031950203 scopus 로고    scopus 로고
    • Inhibitors of bacterial signal peptidases
    • Black MT, Bruton G (1998) Inhibitors of bacterial signal peptidases. Curr Pharmaceut Design 4: 133-154
    • (1998) Curr Pharmaceut Design , vol.4 , pp. 133-154
    • Black, M.T.1    Bruton, G.2
  • 8
    • 0017157814 scopus 로고
    • Biological effects of cyclosporin A: A new antilymphocytic agent
    • Borel JF, Feurer C, Gabler HU, Stähelin H (1976) Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions 6: 468-475
    • (1976) Agents Actions , vol.6 , pp. 468-475
    • Borel, J.F.1    Feurer, C.2    Gabler, H.U.3    Stähelin, H.4
  • 9
    • 84944656315 scopus 로고
    • Emergence of drug-resistant pneumococcal infections in the United States
    • Breiman RF, Butler JC, Tenover FC, Elliot JA, Facklam RR (1994) Emergence of drug-resistant pneumococcal infections in the United States. JAMA 271: 1831-1835
    • (1994) JAMA , vol.271 , pp. 1831-1835
    • Breiman, R.F.1    Butler, J.C.2    Tenover, F.C.3    Elliot, J.A.4    Facklam, R.R.5
  • 10
    • 0022995787 scopus 로고
    • Clavulanic acid, a novel β-lactamase inhibitor - A case study in drug discovery and development
    • Brown AG (1986) Clavulanic acid, a novel β-lactamase inhibitor - a case study in drug discovery and development. Drug Design Deliv 1: 1-21
    • (1986) Drug Design Deliv , vol.1 , pp. 1-21
    • Brown, A.G.1
  • 11
    • 0016913421 scopus 로고
    • Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum
    • Brown AG, Smale TC, King TJ, Hasenkamp R, Thompson RH (1976) Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum. J Chem Soc Perkin Trans I: 1165-1170
    • (1976) J Chem Soc Perkin Trans , vol.1 , pp. 1165-1170
    • Brown, A.G.1    Smale, T.C.2    King, T.J.3    Hasenkamp, R.4    Thompson, R.H.5
  • 12
    • 0031197192 scopus 로고    scopus 로고
    • Antimicrobial agents
    • Bush K (1997) Antimicrobial agents. Curr Opin Chem Biol 1: 169-175
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 169-175
    • Bush, K.1
  • 13
    • 0029739680 scopus 로고    scopus 로고
    • Natural products as a resource for new drugs
    • Clark AM (1996) Natural products as a resource for new drugs. Pharmaceut Res 13: 1133-1141
    • (1996) Pharmaceut Res , vol.13 , pp. 1133-1141
    • Clark, A.M.1
  • 15
    • 0031028432 scopus 로고    scopus 로고
    • Natural products in drug discovery and development
    • Cragg GM, Newman DJ, Snader KM (1997) Natural products in drug discovery and development. J Nat Prod 60: 52-60
    • (1997) J Nat Prod , vol.60 , pp. 52-60
    • Cragg, G.M.1    Newman, D.J.2    Snader, K.M.3
  • 16
    • 0028000948 scopus 로고
    • The echinocandins: Antifungals targeted to the fungal cell wall
    • Debono M (1994) The echinocandins: antifungals targeted to the fungal cell wall. Expert Opin Invest Drugs 3: 821-829
    • (1994) Expert Opin Invest Drugs , vol.3 , pp. 821-829
    • Debono, M.1
  • 18
    • 0020678834 scopus 로고
    • New applications of microbial products
    • Demain AL (1983) New applications of microbial products. Science 219: 709-714
    • (1983) Science , vol.219 , pp. 709-714
    • Demain, A.L.1
  • 19
    • 0028455313 scopus 로고
    • New drug development in the United States from 1963 to 1992
    • DiMasi JA, Seibring MA, Lasagna L (1994) New drug development in the United States from 1963 to 1992. Clin Pharmacol Ther 55: 609-622
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 609-622
    • Dimasi, J.A.1    Seibring, M.A.2    Lasagna, L.3
  • 20
    • 15844391440 scopus 로고    scopus 로고
    • Mechanism of action of the immunosuppressant rapamycin
    • Dumont FJ, Su Q (1996) Mechanism of action of the immunosuppressant rapamycin. Life Sci 58: 373-395
    • (1996) Life Sci , vol.58 , pp. 373-395
    • Dumont, F.J.1    Su, Q.2
  • 21
    • 0017055252 scopus 로고
    • ML-236B and ML-236 C, new inhibitors of cholesterogenesis produced by Penicillium citrinin
    • Endo A, Kuroda M, Tsujita Y (1976) ML-236B and ML-236 C, new inhibitors of cholesterogenesis produced by Penicillium citrinin. J Antibiot 29: 1346-1348
    • (1976) J Antibiot , vol.29 , pp. 1346-1348
    • Endo, A.1    Kuroda, M.2    Tsujita, Y.3
  • 22
    • 0018592266 scopus 로고
    • Monacolin K, a new hypocholesterolemic agent produced by a Monascus species
    • Endo A (1979) Monacolin K, a new hypocholesterolemic agent produced by a Monascus species. J Antibiot 32: 852-854
    • (1979) J Antibiot , vol.32 , pp. 852-854
    • Endo, A.1
  • 24
    • 0030031423 scopus 로고    scopus 로고
    • Strategies to prevent and control the emergence and spread of antimicrobial- resistant microorganisms in hospitals: A challenge to hospital leadership
    • Goldman DA, Weinstein RA, Wenzel RP, Tablan OC, Duma RJ, Gaynes RP, Schlosser J, Martone WJ (1996) Strategies to prevent and control the emergence and spread of antimicrobial- resistant microorganisms in hospitals: a challenge to hospital leadership. JAMA 275: 234-240
    • (1996) JAMA , vol.275 , pp. 234-240
    • Goldman, D.A.1    Weinstein, R.A.2    Wenzel, R.P.3    Tablan, O.C.4    Duma, R.J.5    Gaynes, R.P.6    Schlosser, J.7    Martone, W.J.8
  • 25
    • 0004152299 scopus 로고
    • The fungal dimension of biodiversity: Magnitude, significance, conservation
    • Hawksworth DL (1991) The fungal dimension of biodiversity: magnitude, significance, conservation. Mycol Res 95: 641-655
    • (1991) Mycol Res , vol.95 , pp. 641-655
    • Hawksworth, D.L.1
  • 28
    • 0002085116 scopus 로고    scopus 로고
    • Antibiotics from genetically engineered microorganisms
    • Strohl WR (ed) Marcel Dekker, New York
    • Hutchinson CR (1997) Antibiotics from genetically engineered microorganisms. In: Strohl WR (ed) Biotechnology of antibiotics, 2nd edn. Marcel Dekker, New York, pp 683-702
    • (1997) Biotechnology of Antibiotics, 2nd Edn. , pp. 683-702
    • Hutchinson, C.R.1
  • 29
    • 0001711388 scopus 로고
    • The gibberellin fermentation
    • Jefferys EG (1970) The gibberellin fermentation. Adv Appl Microbiol 13: 283-316
    • (1970) Adv Appl Microbiol , vol.13 , pp. 283-316
    • Jefferys, E.G.1
  • 31
    • 0023245677 scopus 로고
    • FK-506, a novel immunosuppressant isolated from Streptomyces. 1. Fermentation, isolation and physico-chemical and biological characteristics
    • Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka M (1987) FK-506, a novel immunosuppressant isolated from Streptomyces. 1. Fermentation, isolation and physico-chemical and biological characteristics. J Antibiot 40: 1249-1255
    • (1987) J Antibiot , vol.40 , pp. 1249-1255
    • Kino, T.1    Hatanaka, H.2    Hashimoto, M.3    Nishiyama, M.4    Goto, T.5    Okuhara, M.6    Kohsaka, M.7    Aoki, H.8    Imanaka, M.9
  • 32
    • 0025281073 scopus 로고
    • Bioavailability improvement of mycophenolic acid through amino ester derivatization
    • Lee WA, Gu L, Kikszal AR, Chu N, Leung K, Nelson PH (1990) Bioavailability improvement of mycophenolic acid through amino ester derivatization. Pharmaceut Res 7: 161-166.
    • (1990) Pharmaceut Res , vol.7 , pp. 161-166
    • Lee, W.A.1    Gu, L.2    Kikszal, A.R.3    Chu, N.4    Leung, K.5    Nelson, P.H.6
  • 33
    • 0028314541 scopus 로고
    • Multidrug resistance pumps in bacteria: Variations on a theme
    • Lewis K (1994) Multidrug resistance pumps in bacteria: variations on a theme. Trends Biochem Sci 19: 119-123
    • (1994) Trends Biochem Sci , vol.19 , pp. 119-123
    • Lewis, K.1
  • 34
    • 0027157178 scopus 로고
    • FK506 and ciclosporin: Molecular probes for studying intracellular signal transduction
    • Liu J (1993) FK506 and ciclosporin: molecular probes for studying intracellular signal transduction. Trends Pharmacol Sci 14: 182-188
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 182-188
    • Liu, J.1
  • 35
    • 0009465938 scopus 로고    scopus 로고
    • Unnatural natural products by genetic manipulation
    • Sapienza DM, Savage LM (eds) International Business Communications, Southborough, Mass
    • McAlpine J (1998) Unnatural natural products by genetic manipulation. In: Sapienza DM, Savage LM (eds) Natural products II: New technologies to increase efficiency and speed. International Business Communications, Southborough, Mass, pp 251-278
    • (1998) Natural Products II: New Technologies to Increase Efficiency and Speed , pp. 251-278
    • McAlpine, J.1
  • 37
    • 0020607636 scopus 로고
    • Milbemycins, a new family of macrolide antibiotics. Structure determination of milbemycins D, E, F, G, H, J and K
    • Mishima H, Ide J, Muramatsu S, Ono M (1983) Milbemycins, a new family of macrolide antibiotics. Structure determination of milbemycins D, E, F, G, H, J and K. J Antibiot 36: 980-990
    • (1983) J Antibiot , vol.36 , pp. 980-990
    • Mishima, H.1    Ide, J.2    Muramatsu, S.3    Ono, M.4
  • 38
    • 0009526262 scopus 로고    scopus 로고
    • The specter of glycopeptide resistance: Current trends and future considerations
    • Toronto
    • Moellering RC (1997) The specter of glycopeptide resistance: current trends and future considerations. 37th Intersci conf antimicrob agents chemother, Toronto
    • (1997) 37th Intersci Conf Antimicrob Agents Chemother
    • Moellering, R.C.1
  • 39
    • 0029871331 scopus 로고    scopus 로고
    • RP 59500, a streptogramin derivative, is effective in murine listerosis
    • Nichterlein T, Kretschmar M, Hof H (1996) RP 59500, a streptogramin derivative, is effective in murine listerosis. J Chemother 8: 107-112
    • (1996) J Chemother , vol.8 , pp. 107-112
    • Nichterlein, T.1    Kretschmar, M.2    Hof, H.3
  • 40
    • 0029845913 scopus 로고    scopus 로고
    • Multidrug efflux pumps of gram-negative bacteria
    • Nikaido H (1996) Multidrug efflux pumps of gram-negative bacteria. J Bacteriol 178: 5853-5819
    • (1996) J Bacteriol , vol.178 , pp. 5853-5819
    • Nikaido, H.1
  • 41
    • 0009495411 scopus 로고
    • Antitumor antibiotics
    • Perlman D (ed) Academic Press, New York
    • Oki T, Yoshimoto A (1979) Antitumor antibiotics. In: Perlman D (ed) Annual reports on fermentation processes, vol 3. Academic Press, New York, pp 215-251
    • (1979) Annual Reports on Fermentation Processes , vol.3 , pp. 215-251
    • Oki, T.1    Yoshimoto, A.2
  • 42
    • 0031697708 scopus 로고    scopus 로고
    • A new hydroxylase system in Actinomadura sp cells converting compactin to pravastatin
    • Peng Y, Demain AL (1998) A new hydroxylase system in Actinomadura sp cells converting compactin to pravastatin. J Industr Microbiol Biotechnol 20: 373-375
    • (1998) J Industr Microbiol Biotechnol , vol.20 , pp. 373-375
    • Peng, Y.1    Demain, A.L.2
  • 43
    • 0029840799 scopus 로고    scopus 로고
    • Genetically engineered synthesis of natural products: From alkaloids to corrins
    • Roessner CA, Scott AI (1996) Genetically engineered synthesis of natural products: from alkaloids to corrins. Annu Rev Microbiol 50: 467-490
    • (1996) Annu Rev Microbiol , vol.50 , pp. 467-490
    • Roessner, C.A.1    Scott, A.I.2
  • 45
    • 0025767694 scopus 로고
    • A two component-type cytochrome P-450 monooxygenase system in a prokaryote that catalyzes hydroxylation of ML-236B to pravastatin, a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • Serizawa N, Matsuoka T (1991) A two component-type cytochrome P-450 monooxygenase system in a prokaryote that catalyzes hydroxylation of ML-236B to pravastatin, a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochim Biophys Acta 1084: 35-40
    • (1991) Biochim Biophys Acta , vol.1084 , pp. 35-40
    • Serizawa, N.1    Matsuoka, T.2
  • 46
    • 0029671145 scopus 로고    scopus 로고
    • R) revisited: Another point of view
    • R) revisited: another point of view. Experientia 52: 5-13
    • (1996) Experientia , vol.52 , pp. 5-13
    • Stähelin, H.F.1
  • 47
    • 0009524443 scopus 로고
    • Avermectins, antiparasitic lactones produced by Streptomyces avermitilis isolated from a soil in Japan
    • Umezawa H, Demain AL, Hata R, Hutchinson CR (eds) Japan Antibiotic Research Association, Tokyo
    • Stapley EO (1982) Avermectins, antiparasitic lactones produced by Streptomyces avermitilis isolated from a soil in Japan. In: Umezawa H, Demain AL, Hata R, Hutchinson CR (eds) Trends in antibiotic research. Japan Antibiotic Research Association, Tokyo, pp 154-170
    • (1982) Trends in Antibiotic Research , pp. 154-170
    • Stapley, E.O.1
  • 49
    • 0030862013 scopus 로고    scopus 로고
    • Natural products drug discovery - New technologies and approaches
    • Stead P (1997) Natural products drug discovery - new technologies and approaches. Drug Discov Today 2: 256-259
    • (1997) Drug Discov Today , vol.2 , pp. 256-259
    • Stead, P.1
  • 50
    • 0030848819 scopus 로고    scopus 로고
    • Bacterial protein secretion - A target for new antibiotics?
    • Stephens C, Shapiro L (1997) Bacterial protein secretion - a target for new antibiotics? Chem Biol 4: 637-641
    • (1997) Chem Biol , vol.4 , pp. 637-641
    • Stephens, C.1    Shapiro, L.2
  • 51
    • 0027270462 scopus 로고
    • Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew
    • Stierle A, Strobel G, Stierle D (1993) Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew. Science 260: 214-216
    • (1993) Science , vol.260 , pp. 214-216
    • Stierle, A.1    Strobel, G.2    Stierle, D.3
  • 52
    • 33751156911 scopus 로고    scopus 로고
    • Drug firms restock antibacterial arsenal
    • Stinson SC (1996) Drug firms restock antibacterial arsenal. Chem Eng News 74 (39): 75-100
    • (1996) Chem Eng News , vol.74 , Issue.39 , pp. 75-100
    • Stinson, S.C.1
  • 53
    • 0001899377 scopus 로고    scopus 로고
    • Industrial antibiotics: Today and the future
    • Strohl WR (ed) Marcel Dekker, New York
    • Strohl WR (1997) Industrial antibiotics: today and the future. In: Strohl WR (ed) Biotechnology of antibiotics, 2nd edn. Marcel Dekker, New York, pp 1-47
    • (1997) Biotechnology of Antibiotics, 2nd Edn. , pp. 1-47
    • Strohl, W.R.1
  • 54
    • 0031954469 scopus 로고    scopus 로고
    • Recent developments in tetracycline antibiotics
    • Sum P-E, Sum F-W, Projan SJ (1998) Recent developments in tetracycline antibiotics. Curr Pharm Drugs 4: 119-132
    • (1998) Curr Pharm Drugs , vol.4 , pp. 119-132
    • Sum, P.-E.1    Sum, F.-W.2    Projan, S.J.3
  • 56
    • 84978763038 scopus 로고    scopus 로고
    • Screening of novel receptor-active compounds of microbial origin
    • Kleinkauf H, von Döhren H (eds) Products of secondary metabolism. VCH, Weinheim
    • Tanaka H, Omura S (1997) Screening of novel receptor-active compounds of microbial origin. In: Kleinkauf H, von Döhren H (eds) Biotechnology, vol 7. Products of secondary metabolism. VCH, Weinheim, pp 107-132
    • (1997) Biotechnology , vol.7 , pp. 107-132
    • Tanaka, H.1    Omura, S.2
  • 57
    • 0030071463 scopus 로고    scopus 로고
    • The challenges of emerging infectious diseases. Development and spread of multiply-resistant bacterial pathogens
    • Tenover FC, Hughes JM (1996) The challenges of emerging infectious diseases. Development and spread of multiply-resistant bacterial pathogens. JAMA 275: 300-304
    • (1996) JAMA , vol.275 , pp. 300-304
    • Tenover, F.C.1    Hughes, J.M.2
  • 58
    • 0029360580 scopus 로고
    • Mitomycin C: Small, fast and deadly (but very selective)
    • Tomasz M (1995) Mitomycin C: small, fast and deadly (but very selective). Curr Biol 2: 575-579
    • (1995) Curr Biol , vol.2 , pp. 575-579
    • Tomasz, M.1
  • 61
    • 0020393784 scopus 로고
    • Low-molecular-weight inhibitors of microbial origin
    • Umezawa H (1982) Low-molecular-weight inhibitors of microbial origin. Annu Rev Microbiol 36: 75-99
    • (1982) Annu Rev Microbiol , vol.36 , pp. 75-99
    • Umezawa, H.1
  • 62
    • 0027365548 scopus 로고
    • Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium
    • Vaara M (1993) Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium. Antimicrob Agents Chemother 37: 2255-2260
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2255-2260
    • Vaara, M.1
  • 63
    • 0029854741 scopus 로고    scopus 로고
    • The combinatorial chemistry of nature
    • Verdine GL (1996) The combinatorial chemistry of nature. Nature 384 (Suppl): 11-13
    • (1996) Nature , vol.384 , Issue.SUPPL. , pp. 11-13
    • Verdine, G.L.1
  • 64
    • 0016724057 scopus 로고
    • Rapamycin (AY 22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle
    • Vezina D, Kudelski A, Sehgal SN (1975) Rapamycin (AY 22,989), a new antifungal antibiotic. 1. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot 28: 721-726
    • (1975) J Antibiot , vol.28 , pp. 721-726
    • Vezina, D.1    Kudelski, A.2    Sehgal, S.N.3
  • 65
    • 0001193810 scopus 로고
    • Ergot alkaloids
    • Rose AH (ed) Secondary products of metabolism. Academic Press, London
    • Vining LC, Taber WA (1979) Ergot alkaloids. In: Rose AH (ed) Economic microbiology, vol 3: Secondary products of metabolism. Academic Press, London, pp 389-420
    • (1979) Economic Microbiology , vol.3 , pp. 389-420
    • Vining, L.C.1    Taber, W.A.2
  • 66
    • 0028896166 scopus 로고
    • Campothecin and taxol: Discovery to clinic
    • Wall ME, Wani MC (1995) Campothecin and taxol: discovery to clinic. Cancer Res 55: 753-760
    • (1995) Cancer Res , vol.55 , pp. 753-760
    • Wall, M.E.1    Wani, M.C.2
  • 67
    • 0000334044 scopus 로고    scopus 로고
    • Antifungal drug resistance in Candida albicans
    • White TC (1997) Antifungal drug resistance in Candida albicans. ASM News 63: 427-433
    • (1997) ASM News , vol.63 , pp. 427-433
    • White, T.C.1
  • 68
    • 0000587715 scopus 로고
    • Iron complex products (siderophores)
    • Pape H, Rehm H-J (eds) Microbial products 2. VCH, Weinheim
    • Winkelmann G (1986) Iron complex products (siderophores). In: Pape H, Rehm H-J (eds) Biotechnology, vol 4. Microbial products 2. VCH, Weinheim, pp 215-243
    • (1986) Biotechnology , vol.4 , pp. 215-243
    • Winkelmann, G.1


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