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Volumn 84, Issue 9 SUPPL. 1, 1999, Pages 20-28

Amiodarone: Ionic and cellular mechanisms of action of the most promising class III agent

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; DEETHYLAMIODARONE; DRUG METABOLITE; ION CHANNEL; LIOTHYRONINE; MESSENGER RNA;

EID: 0032745315     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(99)00698-0     Document Type: Conference Paper
Times cited : (206)

References (85)
  • 1
    • 0024321898 scopus 로고
    • Preliminary report: Effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction
    • Preliminary report effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction . N Engl J Med. 321:1989;406-412.
    • (1989) N Engl J Med , vol.321 , pp. 406-412
  • 2
    • 0026752875 scopus 로고
    • Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction
    • Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction. N Engl J Med. 327:1992;227-233.
    • (1992) N Engl J Med , vol.327 , pp. 227-233
  • 4
    • 0025542167 scopus 로고
    • Efficacy and safety of quinidine therapy for the maintenance of sinus rhythm after cardioversion: A meta-analysis of randomized control trials
    • Coplen S.E., Antman E.M., Berlin J.A., Hewitt P., Chalmers T.C. Efficacy and safety of quinidine therapy for the maintenance of sinus rhythm after cardioversion a meta-analysis of randomized control trials . Circulation. 82:1990;1106-1116.
    • (1990) Circulation , vol.82 , pp. 1106-1116
    • Coplen, S.E.1    Antman, E.M.2    Berlin, J.A.3    Hewitt, P.4    Chalmers, T.C.5
  • 5
    • 0025934221 scopus 로고
    • An antiarrhythmic drug experience in 941 patients resuscitated from an initial cardiac arrest between 1970 and 1985
    • Hallstrom A.P., Cobb L.A., Yu B.H., Weaver W.D., Fahrenbruch C.E. An antiarrhythmic drug experience in 941 patients resuscitated from an initial cardiac arrest between 1970 and 1985. Am J Cardiol. 68:1991;1025-1031.
    • (1991) Am J Cardiol , vol.68 , pp. 1025-1031
    • Hallstrom, A.P.1    Cobb, L.A.2    Yu, B.H.3    Weaver, W.D.4    Fahrenbruch, C.E.5
  • 6
    • 0025936173 scopus 로고
    • Quinidine-related mortality in the short-to-medium-term treatment of ventricular arrhythmias: A meta-analysis
    • Morganroth J., Goin J.E. Quinidine-related mortality in the short-to-medium-term treatment of ventricular arrhythmias a meta-analysis . Circulation. 84:1991;1977-1983.
    • (1991) Circulation , vol.84 , pp. 1977-1983
    • Morganroth, J.1    Goin, J.E.2
  • 7
    • 0027381958 scopus 로고
    • Controlling cardiac arrhythmias by lengthening repolarization: Historical overview
    • Singh B.N. Controlling cardiac arrhythmias by lengthening repolarization historical overview . Am J Cardiol. 72:(suppl):1993;18F-24F.
    • (1993) Am J Cardiol , vol.72 , Issue.SUPPL
    • Singh, B.N.1
  • 8
    • 0028849874 scopus 로고
    • Expanding indications for the use of Class III agents in patients at high risk for sudden death
    • Singh B.N. Expanding indications for the use of Class III agents in patients at high risk for sudden death. J Cardiovasc Electrophysiol. 6:1995;887-900.
    • (1995) J Cardiovasc Electrophysiol , vol.6 , pp. 887-900
    • Singh, B.N.1
  • 12
    • 0028883528 scopus 로고
    • Contemporary clinical trials in ventricular tachycardia and fibrillation: Implications of ESVEM, CASCADE, and CASH for clinical management
    • Anderson J.L. Contemporary clinical trials in ventricular tachycardia and fibrillation implications of ESVEM, CASCADE, and CASH for clinical management . J Cardiovasc Electrophysiol. 6:1995;880-886.
    • (1995) J Cardiovasc Electrophysiol , vol.6 , pp. 880-886
    • Anderson, J.L.1
  • 14
    • 0031583760 scopus 로고    scopus 로고
    • Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: Meta-analysis of individual data from 6500 patients in randomised trials
    • Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure meta-analysis of individual data from 6500 patients in randomised trials . Lancet. 350:1997;1417-1424.
    • (1997) Lancet , vol.350 , pp. 1417-1424
  • 15
    • 0030694664 scopus 로고    scopus 로고
    • Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death
    • Sim I., McDonald M., Lavori P.W., Norbutas C.M., Hlatky M.A. Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death. Circulation. 96:1997;2823-2829.
    • (1997) Circulation , vol.96 , pp. 2823-2829
    • Sim, I.1    McDonald, M.2    Lavori, P.W.3    Norbutas, C.M.4    Hlatky, M.A.5
  • 16
    • 0020513561 scopus 로고
    • Amiodarone: Historical development and pharmacologic profile
    • Singh B.N. Amiodarone historical development and pharmacologic profile . Am Heart J. 106:1983;788-797.
    • (1983) Am Heart J , vol.106 , pp. 788-797
    • Singh, B.N.1
  • 17
    • 0021336827 scopus 로고
    • Amiodarone: Electrophysiologic actions, pharmacokinetics and clinical effects
    • Zipes D.P., Prystowsky E.N., Heger J.J. Amiodarone electrophysiologic actions, pharmacokinetics and clinical effects . J Am Coll Cardiol. 3:1984;1059-1071.
    • (1984) J Am Coll Cardiol , vol.3 , pp. 1059-1071
    • Zipes, D.P.1    Prystowsky, E.N.2    Heger, J.J.3
  • 18
    • 0030773253 scopus 로고    scopus 로고
    • Cellular electropharmacology of amiodarone
    • Kodama I., Kamiya K., Toyama J. Cellular electropharmacology of amiodarone. Cardiovasc Res. 35:1997;13-29.
    • (1997) Cardiovasc Res , vol.35 , pp. 13-29
    • Kodama, I.1    Kamiya, K.2    Toyama, J.3
  • 19
    • 0023158384 scopus 로고
    • Amiodarone
    • Mason J.W. Amiodarone. N Engl J Med. 316:1987;455-466.
    • (1987) N Engl J Med , vol.316 , pp. 455-466
    • Mason, J.W.1
  • 20
    • 0026664060 scopus 로고
    • Amiodarone: Pharmacology, clinical actions, and relationships between them
    • Nattel S., Talajic M., Fermini B., Roy D. Amiodarone pharmacology, clinical actions, and relationships between them . J Cardiovasc Electrophysiol. 3:1992;266-280.
    • (1992) J Cardiovasc Electrophysiol , vol.3 , pp. 266-280
    • Nattel, S.1    Talajic, M.2    Fermini, B.3    Roy, D.4
  • 23
    • 0030869622 scopus 로고    scopus 로고
    • Amiodarone inhibits production of tumor necrosis factor-α By human mononuclear cells: A possible mechanism for its effect in heart failure
    • Matsumori A., Ono K., Nishio R., Nose Y., Sasayama S. Amiodarone inhibits production of tumor necrosis factor-α by human mononuclear cells a possible mechanism for its effect in heart failure . Circulation. 96:1997;1386-1389.
    • (1997) Circulation , vol.96 , pp. 1386-1389
    • Matsumori, A.1    Ono, K.2    Nishio, R.3    Nose, Y.4    Sasayama, S.5
  • 24
    • 0020678152 scopus 로고
    • Amiodarone blocks inactivated cardiac sodium channels
    • Mason J.W., Hondeghem L.M., Katzung B.G. Amiodarone blocks inactivated cardiac sodium channels. Pflügers Arch. 396:1983;79-81.
    • (1983) Pflügers Arch , vol.396 , pp. 79-81
    • Mason, J.W.1    Hondeghem, L.M.2    Katzung, B.G.3
  • 25
    • 0021168376 scopus 로고
    • Block of inactivated sodium channels and of depolarization-induced automaticity in guinea pig papillary muscle by amiodarone
    • Mason J.W., Hondeghem L.M., Katzung B.G. Block of inactivated sodium channels and of depolarization-induced automaticity in guinea pig papillary muscle by amiodarone. Circ Res. 55:1984;277-285.
    • (1984) Circ Res , vol.55 , pp. 277-285
    • Mason, J.W.1    Hondeghem, L.M.2    Katzung, B.G.3
  • 26
    • 0023216944 scopus 로고
    • max of guinea-pig ventricular action potentials by amiodarone and desethylamiodarone
    • max of guinea-pig ventricular action potentials by amiodarone and desethylamiodarone. Br J Pharmacol. 92:1987;97-103.
    • (1987) Br J Pharmacol , vol.92 , pp. 97-103
    • Pallandi, R.T.1    Campbell, T.J.2
  • 29
    • 0000993544 scopus 로고
    • Acute and chronic effects of amiodarone on action potential and ionic currents in single rabbit ventricular myocytes
    • J. Toyama, M. Hiraoka, & I. Kodama. Boca Raton: CRC Press
    • Kamiya K., Cheng J., Kodama I., Toyama J. Acute and chronic effects of amiodarone on action potential and ionic currents in single rabbit ventricular myocytes. Toyama J., Hiraoka M., Kodama I. Recent Progress in Electropharmacology of the Heart. 1995;139-149 CRC Press, Boca Raton.
    • (1995) Recent Progress in Electropharmacology of the Heart , pp. 139-149
    • Kamiya, K.1    Cheng, J.2    Kodama, I.3    Toyama, J.4
  • 30
    • 0026722630 scopus 로고
    • Effects of long-term oral administration of amiodarone on the electromechanical performance of rabbit ventricular muscle
    • Kodama I., Suzuki R., Kamiya K., Iwata H., Toyama J. Effects of long-term oral administration of amiodarone on the electromechanical performance of rabbit ventricular muscle. Br J Pharmacol. 107:1992;502-509.
    • (1992) Br J Pharmacol , vol.107 , pp. 502-509
    • Kodama, I.1    Suzuki, R.2    Kamiya, K.3    Iwata, H.4    Toyama, J.5
  • 32
    • 0023266763 scopus 로고
    • Amiodarone-induced block of sodium current in isolated cardiac cells
    • Follmer C.H., Aomine M., Yeh J.Z., Singer D.H. Amiodarone-induced block of sodium current in isolated cardiac cells. J Pharmacol Exp Ther. 243:1987;187-194.
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 187-194
    • Follmer, C.H.1    Aomine, M.2    Yeh, J.Z.3    Singer, D.H.4
  • 33
    • 0023912885 scopus 로고
    • + channels by antiarrhythmic drugs: The effect of amiodarone, propafenone and diprafenone
    • + channels by antiarrhythmic drugs the effect of amiodarone, propafenone and diprafenone . J Membrane Biol. 102:1988;105-119.
    • (1988) J Membrane Biol , vol.102 , pp. 105-119
    • Kohlhardt, M.1    Fichtner, H.2
  • 34
    • 0024358289 scopus 로고
    • Amiodarone: Biochemical evidence for binding to a receptor for Class I drugs associated with the rat cardiac sodium channel
    • Sheldon R.S., Hill R.J., Cannon N.J., Duff H.J. Amiodarone biochemical evidence for binding to a receptor for Class I drugs associated with the rat cardiac sodium channel . Circ Res. 65:1989;477-482.
    • (1989) Circ Res , vol.65 , pp. 477-482
    • Sheldon, R.S.1    Hill, R.J.2    Cannon, N.J.3    Duff, H.J.4
  • 35
    • 0024760583 scopus 로고
    • Amiodarone blocks calcium current in single guinea pig ventricular myocytes
    • Nishimura M., Follmer C.H., Singer D.H. Amiodarone blocks calcium current in single guinea pig ventricular myocytes. J Pharmacol Exp Ther. 251:1989;650-659.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 650-659
    • Nishimura, M.1    Follmer, C.H.2    Singer, D.H.3
  • 36
    • 0025952729 scopus 로고
    • Voltage- And use-dependent modulation of calcium channel current in guinea pig ventricular cells by amiodarone and des-oxo-amiodarone
    • Valenzuela C., Bennett P.B. Voltage- and use-dependent modulation of calcium channel current in guinea pig ventricular cells by amiodarone and des-oxo-amiodarone. J Cardiovasc Pharmacol. 17:1991;894-902.
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 894-902
    • Valenzuela, C.1    Bennett, P.B.2
  • 37
    • 0030008036 scopus 로고    scopus 로고
    • Comparison of the chronic and acute effects of amiodarone on the calcium and potassium currents in rabbit isolated cardiac myocytes
    • Varro A., Virag L., Papp J.G. Comparison of the chronic and acute effects of amiodarone on the calcium and potassium currents in rabbit isolated cardiac myocytes. Br J Pharmacol. 117:1996;1181-1186.
    • (1996) Br J Pharmacol , vol.117 , pp. 1181-1186
    • Varro, A.1    Virag, L.2    Papp, J.G.3
  • 39
    • 0025860749 scopus 로고
    • Suppression of time-dependent outward current in guinea pig ventricular myocytes: Actions of quinidine and amiodarone
    • Balser J.R., Bennett P.B., Hondeghem L.M., Roden D.M. Suppression of time-dependent outward current in guinea pig ventricular myocytes actions of quinidine and amiodarone . Circ Res. 69:1991;519-529.
    • (1991) Circ Res , vol.69 , pp. 519-529
    • Balser, J.R.1    Bennett, P.B.2    Hondeghem, L.M.3    Roden, D.M.4
  • 40
    • 0025351245 scopus 로고
    • + current: Differential sensitivity to block by class III antiarrhythmic agents
    • + current differential sensitivity to block by class III antiarrhythmic agents . J Gen Physiol. 96:1990;195-215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 42
    • 0031080286 scopus 로고    scopus 로고
    • + channel activities of cultured rat cardiomyocytes
    • + channel activities of cultured rat cardiomyocytes. J Mol Cell Cardiol. 29:1997;617-627.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 617-627
    • Guo, W.1    Kamiya, K.2    Toyama, J.3
  • 45
    • 0030431219 scopus 로고    scopus 로고
    • Inhibitory effect of amiodarone on the muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells
    • Watanabe Y., Hara Y., Tamagawa M., Nakaya H. Inhibitory effect of amiodarone on the muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells. J Pharmacol Exp Ther. 279:1996;617-624.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 617-624
    • Watanabe, Y.1    Hara, Y.2    Tamagawa, M.3    Nakaya, H.4
  • 46
    • 85046525314 scopus 로고    scopus 로고
    • ATP) channels but retards hypoxic or ischemic myocardial contracture. (Abstr.)
    • 45
    • ATP) channels but retards hypoxic or ischemic myocardial contracture. (Abstr.) Jpn J Pharmacol 1997;73:S-1,45.
    • (1997) Jpn J Pharmacol , vol.73
    • Takizawa, T.1    Nakaya, H.2
  • 47
    • 0003240583 scopus 로고
    • Potassium channels and the regulation of refractoriness and heart rate
    • D. Escande, & N. Standen. Paris: Springer-Verlag
    • + Channels in Cardiovascular Medicine. 1993;53-68 Springer-Verlag, Paris.
    • (1993) + Channels in Cardiovascular Medicine , pp. 53-68
    • Carmeliet, E.1
  • 48
    • 0024566174 scopus 로고
    • Rate-related electrophysiologic effects of long-term administration of amiodarone on canine ventricular myocardium in vivo
    • Anderson K.P., Walker R., Dustman T., Lux R.L., Ershler P.R., Kates R.E., Urie P.M. Rate-related electrophysiologic effects of long-term administration of amiodarone on canine ventricular myocardium in vivo. Circulation. 79:1989;948-958.
    • (1989) Circulation , vol.79 , pp. 948-958
    • Anderson, K.P.1    Walker, R.2    Dustman, T.3    Lux, R.L.4    Ershler, P.R.5    Kates, R.E.6    Urie, P.M.7
  • 49
    • 0021150775 scopus 로고
    • Electrophysiologic effects of amiodarone: Experimental and clinical observation relative to serum and tissue drug concentrations
    • Ikeda N., Nademanee K., Kannan R., Singh B.N. Electrophysiologic effects of amiodarone experimental and clinical observation relative to serum and tissue drug concentrations . Am Heart J. 108:1984;890-898.
    • (1984) Am Heart J , vol.108 , pp. 890-898
    • Ikeda, N.1    Nademanee, K.2    Kannan, R.3    Singh, B.N.4
  • 50
    • 0023857103 scopus 로고
    • Electrophysiologic effects of desethylamiodarone, an active metabolite of amiodarone: Comparison with amiodarone during chronic administration in rabbits
    • Kato R., Venkatesh N., Kamiya K., Yabek S., Kannan R., Singh B.N. Electrophysiologic effects of desethylamiodarone, an active metabolite of amiodarone comparison with amiodarone during chronic administration in rabbits . Am Heart J. 115:1988;351-359.
    • (1988) Am Heart J , vol.115 , pp. 351-359
    • Kato, R.1    Venkatesh, N.2    Kamiya, K.3    Yabek, S.4    Kannan, R.5    Singh, B.N.6
  • 51
    • 0014829352 scopus 로고
    • The effect of amiodarone, a new anti-anginal drug, on cardiac muscle
    • Singh B.N., Vaughan Williams E.M. The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol. 39:1970;657-667.
    • (1970) Br J Pharmacol , vol.39 , pp. 657-667
    • Singh, B.N.1    Vaughan Williams, E.M.2
  • 52
    • 0022977498 scopus 로고
    • Electropharmacology of amiodarone: Absence of relationship to serum, myocardial, and cardiac sarcolemmal membrane drug concentrations
    • Venkatesh N., Somani P., Bersohn M., Phair R., Kato R., Singh B.N. Electropharmacology of amiodarone absence of relationship to serum, myocardial, and cardiac sarcolemmal membrane drug concentrations . Am Heart J. 112:1986;916-922.
    • (1986) Am Heart J , vol.112 , pp. 916-922
    • Venkatesh, N.1    Somani, P.2    Bersohn, M.3    Phair, R.4    Kato, R.5    Singh, B.N.6
  • 53
    • 0029970753 scopus 로고    scopus 로고
    • Acute and chronic effects of amiodarone on mammalian ventricular cells
    • Kodama I., Kamiya K., Honjo H., Toyama J. Acute and chronic effects of amiodarone on mammalian ventricular cells. Jpn Heart J. 37:1996;719-730.
    • (1996) Jpn Heart J , vol.37 , pp. 719-730
    • Kodama, I.1    Kamiya, K.2    Honjo, H.3    Toyama, J.4
  • 54
    • 0000400026 scopus 로고
    • Modulation of repolarizing potassium channels and Kv1.5 mRNA by long-term treatment with amiodarone
    • (Abstr.)
    • Kamiya K., Cheng J., Kodama I., Toyama J. Modulation of repolarizing potassium channels and Kv1.5 mRNA by long-term treatment with amiodarone. (Abstr.) Circulation. 92:1995;SI373.
    • (1995) Circulation , vol.92 , pp. 373
    • Kamiya, K.1    Cheng, J.2    Kodama, I.3    Toyama, J.4
  • 55
    • 0011170664 scopus 로고
    • Transcriptional regulation of rat Kv1.5 potassium channel gene by amiodarone and thyroid hormone
    • (Abstr.)
    • Peele M.E. Transcriptional regulation of rat Kv1.5 potassium channel gene by amiodarone and thyroid hormone. (Abstr.) Circulation. 92:1995;SI373.
    • (1995) Circulation , vol.92 , pp. 373
    • Peele, M.E.1
  • 56
    • 0023875511 scopus 로고
    • The antiarrhythmic efficacy of amiodarone and desethylamiodarone, alone and in combination, in dogs with acute myocardial infarction
    • Nattel S., Davies M., Quantz M. The antiarrhythmic efficacy of amiodarone and desethylamiodarone, alone and in combination, in dogs with acute myocardial infarction. Circulation. 77:1988;200-208.
    • (1988) Circulation , vol.77 , pp. 200-208
    • Nattel, S.1    Davies, M.2    Quantz, M.3
  • 57
    • 0023236536 scopus 로고
    • Frequency-dependent effects of amiodarone on atrioventricular nodal function and slow-channel action potentials: Evidence for calcium channel-blocking activity
    • Nattel S., Talajic M., Quantz M., DeRoode M. Frequency-dependent effects of amiodarone on atrioventricular nodal function and slow-channel action potentials evidence for calcium channel-blocking activity . Circulation. 76:1987;442-449.
    • (1987) Circulation , vol.76 , pp. 442-449
    • Nattel, S.1    Talajic, M.2    Quantz, M.3    Deroode, M.4
  • 58
    • 0022568683 scopus 로고
    • Effects of amiodarone and its metabolite, desethylamiodarone, on the electrophysiologic properties of isolated cardiac muscle
    • Yabek S.M., Kato R., Singh B.N. Effects of amiodarone and its metabolite, desethylamiodarone, on the electrophysiologic properties of isolated cardiac muscle. J Cardiovasc Pharmacol. 8:1986;197-207.
    • (1986) J Cardiovasc Pharmacol , vol.8 , pp. 197-207
    • Yabek, S.M.1    Kato, R.2    Singh, B.N.3
  • 59
    • 0022499510 scopus 로고
    • Pharmacodynamic studies of amiodarone and its active N-desethyl metabolite
    • Nattel S. Pharmacodynamic studies of amiodarone and its active N-desethyl metabolite. J Cardiovasc Pharmacol. 8:1986;771-777.
    • (1986) J Cardiovasc Pharmacol , vol.8 , pp. 771-777
    • Nattel, S.1
  • 60
    • 0023136309 scopus 로고
    • Comparative electrophysiologic effects of intravenous amiodarone and desethylamiodarone in dogs: Evidence for clinically relevant activity of the metabolite
    • Talajic M., DeRoode M.R., Nattel S. Comparative electrophysiologic effects of intravenous amiodarone and desethylamiodarone in dogs evidence for clinically relevant activity of the metabolite . Circulation. 75:1987;265-271.
    • (1987) Circulation , vol.75 , pp. 265-271
    • Talajic, M.1    Deroode, M.R.2    Nattel, S.3
  • 61
    • 0020557382 scopus 로고
    • Amiodarone and thyroid function: Clinical implications during antiarrhythmic therapy
    • Singh B.N., Nademanee K. Amiodarone and thyroid function clinical implications during antiarrhythmic therapy . Am Heart J. 106:1983;857-868.
    • (1983) Am Heart J , vol.106 , pp. 857-868
    • Singh, B.N.1    Nademanee, K.2
  • 62
    • 0026523117 scopus 로고
    • In vivo effects of amiodarone on cardiac β-adrenoceptor density and heart rate require thyroid hormones
    • Yin Y.L., Perret G.Y., Nicolas P., Vassy R., Uzzan B., Tod M. In vivo effects of amiodarone on cardiac β-adrenoceptor density and heart rate require thyroid hormones. J Cardiovasc Pharmacol. 19:1992;541-545.
    • (1992) J Cardiovasc Pharmacol , vol.19 , pp. 541-545
    • Yin, Y.L.1    Perret, G.Y.2    Nicolas, P.3    Vassy, R.4    Uzzan, B.5    Tod, M.6
  • 63
    • 0028168409 scopus 로고
    • 3 and amiodarone on the contractility and the density of β-adrenoceptors of chicken cardiac myocytes
    • 3 and amiodarone on the contractility and the density of β-adrenoceptors of chicken cardiac myocytes. Eur J Pharmacol. 261:1994;97-104.
    • (1994) Eur J Pharmacol , vol.261 , pp. 97-104
    • Yin, Y.1    Vassy, R.2    Nicolas, P.3    Perret, G.Y.4    Laurent, S.5
  • 64
    • 0022875827 scopus 로고
    • Cardiac electrophysiologic effects of acute and chronic amiodarone administration in the isolated perfused rabbit heart: Altered thyroid hormone metabolism
    • Patterson E., Walden K.M., Khazaeli M.B., Montgomery D.G., Lucchesi B.R. Cardiac electrophysiologic effects of acute and chronic amiodarone administration in the isolated perfused rabbit heart altered thyroid hormone metabolism . J Pharmacol Exp Ther. 239:1986;179-184.
    • (1986) J Pharmacol Exp Ther , vol.239 , pp. 179-184
    • Patterson, E.1    Walden, K.M.2    Khazaeli, M.B.3    Montgomery, D.G.4    Lucchesi, B.R.5
  • 65
    • 0023212497 scopus 로고
    • Lack of relation between the ventricular refractory period prolongation by amiodarone and the thyroid state in rats
    • Lambert C., Cardinal R., Vermeulen M., Lamontagne D., Nadeau R., Paradis P., Rouleau J.L. Lack of relation between the ventricular refractory period prolongation by amiodarone and the thyroid state in rats. J Pharm Exp Ther. 242:1987;320-325.
    • (1987) J Pharm Exp Ther , vol.242 , pp. 320-325
    • Lambert, C.1    Cardinal, R.2    Vermeulen, M.3    Lamontagne, D.4    Nadeau, R.5    Paradis, P.6    Rouleau, J.L.7
  • 67
    • 0003213214 scopus 로고    scopus 로고
    • Ionic mechanisms of electrophysiologic effects of chronic amiodarone therapy and hypothyroidism: Does amiodarone act via cardiac hypothyroidism?
    • (Abstr.)
    • Bosch R.F., Li G.R., Gaspo R., Nattel S. Ionic mechanisms of electrophysiologic effects of chronic amiodarone therapy and hypothyroidism Does amiodarone act via cardiac hypothyroidism? (Abstr.) Circulation. 94:1996;SI161.
    • (1996) Circulation , vol.94 , pp. 161
    • Bosch, R.F.1    Li, G.R.2    Gaspo, R.3    Nattel, S.4
  • 68
    • 0021123286 scopus 로고
    • Amiodarone inhibits the conversion of thyroxin to triiodothyronine in isolated rat hepatocytes
    • Aanderaud S., Sundsfjord J., Aarbokke J. Amiodarone inhibits the conversion of thyroxin to triiodothyronine in isolated rat hepatocytes. Endocrinology. 115:1984;1605-1608.
    • (1984) Endocrinology , vol.115 , pp. 1605-1608
    • Aanderaud, S.1    Sundsfjord, J.2    Aarbokke, J.3
  • 70
    • 0024238212 scopus 로고
    • Amiodarone alters thyroxin transfer and distribution in humans
    • Kaptein E.M., Egodage P.M., Hoopes M.T., Burger A.G. Amiodarone alters thyroxin transfer and distribution in humans. Metabolism. 37:1988;1107-1113.
    • (1988) Metabolism , vol.37 , pp. 1107-1113
    • Kaptein, E.M.1    Egodage, P.M.2    Hoopes, M.T.3    Burger, A.G.4
  • 71
    • 0020319067 scopus 로고
    • 3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs
    • 3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs. FEBS Lett. 140:1982;229-233.
    • (1982) FEBS Lett , vol.140 , pp. 229-233
    • Krenning, E.P.1    Docter, R.2    Bernard, B.3    Visser, T.4    Hennemann, G.5
  • 73
    • 0023094217 scopus 로고
    • Interaction of amiodarone and desethylamiodarone with solubilized nuclear thyroid hormone receptors
    • Latham K.R., Sellitti D.F., Goldstein R.E. Interaction of amiodarone and desethylamiodarone with solubilized nuclear thyroid hormone receptors. J Am Coll Cardiol. 9:1987;872-876.
    • (1987) J Am Coll Cardiol , vol.9 , pp. 872-876
    • Latham, K.R.1    Sellitti, D.F.2    Goldstein, R.E.3
  • 74
    • 0025021268 scopus 로고
    • Differential and tissue specific regulation of multiple rat c-erbA messenger RNA species by thyroid hormone
    • Hodin R.A., Lazar M.A., Chin W.W. Differential and tissue specific regulation of multiple rat c-erbA messenger RNA species by thyroid hormone. J Clin Invest. 85:1990;101-105.
    • (1990) J Clin Invest , vol.85 , pp. 101-105
    • Hodin, R.A.1    Lazar, M.A.2    Chin, W.W.3
  • 76
    • 0029100396 scopus 로고
    • 1, whereas disopyramide, lignocaine, propafenone, metoprolol, d,l-sotalol, and verapamil have no inhibitory effect
    • 1, whereas disopyramide, lignocaine, propafenone, metoprolol, d,l-sotalol, and verapamil have no inhibitory effect. J Cardiovasc Pharmacol. 26:1995;222-226.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 222-226
    • Drvota, V.1    Carlsson, B.2    Haggblad, J.3    Sylven, C.4
  • 78
    • 0021321309 scopus 로고
    • Does amiodarone affect heart rate by inhibiting the intracellular generation of triiodothyronine from thyroxine?
    • Lindenmeyer M., Sporri S., Staubli M., Studer A., Studer H. Does amiodarone affect heart rate by inhibiting the intracellular generation of triiodothyronine from thyroxine? Br J Pharmacol. 82:1984;275-280.
    • (1984) Br J Pharmacol , vol.82 , pp. 275-280
    • Lindenmeyer, M.1    Sporri, S.2    Staubli, M.3    Studer, A.4    Studer, H.5
  • 79
    • 0022592210 scopus 로고
    • The effects of amiodarone on the electrocardiogram of the guinea-pig are not explained by interaction with thyroid hormone metabolism alone
    • Staubli M., Studer H. The effects of amiodarone on the electrocardiogram of the guinea-pig are not explained by interaction with thyroid hormone metabolism alone. Br J Pharmacol. 88:1986;405-410.
    • (1986) Br J Pharmacol , vol.88 , pp. 405-410
    • Staubli, M.1    Studer, H.2
  • 81
    • 0029120662 scopus 로고
    • Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, d,l-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs
    • Finance O., Manning A., Chatelain P. Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, d,l-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs. J Cardiovasc Pharmacol. 26:1995;570-576.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 570-576
    • Finance, O.1    Manning, A.2    Chatelain, P.3
  • 83
    • 0029090677 scopus 로고
    • SR 33589, a new amiodarone-like agent: Effect on ischemia- And reperfusion-induced arrhythmias in anesthetized rats
    • Manning A.S., Bruyninckx C., Ramboux J., Chatelain P. SR 33589, a new amiodarone-like agent effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats . J Cardiovasc Pharmacol. 26:1995;453-461.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 453-461
    • Manning, A.S.1    Bruyninckx, C.2    Ramboux, J.3    Chatelain, P.4
  • 84
    • 0030435124 scopus 로고    scopus 로고
    • Electrophysiological effects of a novel, short-acting and potent ester derivative of amiodarone, ATI-2001, in guinea pig isolated heart
    • Raatikainen M.J.P., Napolitano C.A., Druzgala P., Dennis D.M. Electrophysiological effects of a novel, short-acting and potent ester derivative of amiodarone, ATI-2001, in guinea pig isolated heart. J Pharmacol Exp Ther. 277:1996;1454-1463.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1454-1463
    • Raatikainen, M.J.P.1    Napolitano, C.A.2    Druzgala, P.3    Dennis, D.M.4


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