Halothane attenuation of calcium sensitivity in airway smooth muscle: Mechanisms of action during muscarinic receptor stimulation

Anesthesiology

Volumn 87, Issue 1, 1997, Pages 94-101

  Bremerich, Dorothee H ^b   Hirasaki, Akihito ^b   Jones, Keith A ^a   Warner, David O ^b  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

escin; Calcium sensitivity; Lung, trachea: canine; smooth muscle; Muscle, smooth: airway, trachea; Pharmacology: acetylcholine; guanosine 5' triphosphate (GTP); guanosine 5' O (3 thiotriphosphate) (GTP S); guanosine 5' O (2 thiodiphosphate) (GDP S); halothane; phorbol 12,13 dibutyrate (PDBu); Second messenger systems: GTP binding proteins; protein kinase C

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; HALOTHANE; MUSCARINIC RECEPTOR;

AIRWAY CONSTRICTION; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GENERAL ANESTHESIA; INHALATIONAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; SMOOTH MUSCLE;

ANESTHETICS, INHALATION; ANIMALS; CALCIUM; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HALOTHANE; MALE; MUSCARINIC AGONISTS; MUSCLE, SMOOTH; RECEPTORS, MUSCARINIC; RESPIRATORY PHYSIOLOGY; RESPIRATORY SYSTEM;

EID: 0030844040     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199707000-00013     Document Type: Article

References (43)

1. 2+ in airway smooth muscle independently of cyclic nucleotides. Am J Physiol 1995; 268:L166-72
2. Jones KA, Wong GY, Lorenz RR, Warner DO, Sieck GC: Effects of halothane on the relationship between cytosolic calcium and force in airway smooth muscle. Am J Physiol 1994; 266:L199-L204
3. Yamakage M: Direct inhibitory mechanisms of halothane on canine tracheal smooth muscle contraction. ANESTHESIOLOGY 1992; 77:546-53
4. 2+ channels in porcine tracheal smooth muscle cells. Am J Physiol 1995; 268:L187-91
5. 2+ sensitivity during muscarinic receptor stimulation of airway smooth muscle. Am J Physiol 1996; 271:L719-25
6. Gerthoffer WT, Murphy RA: Myosin phosphorylation and regulation of cross-bridge cycle in tracheal smooth muscle. Am J Physiol 1983; 244:C182-7
7. Kamm KE, Stull JT: The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol 1985; 25:593-620
8. 2+ sensitization of smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem 1991; 266:1708-15
9. 2+ J Biol Chem 1989; 264:5339-42
10. 2+ sensitization of smooth muscle. Proc Natl Acad Sci 1996; 93:1340-5
11. Hirata K, Kikuchi A, Sasiki T, Kuroda S, Kaibuchi K, Matsuura Y, Seki H, Saida K, Takai Y: Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem 1992; 267:8719-22
12. Kubota Y, Nomura M, Kamm KE, Mumby MC, Stull JT: GTPγγS-dependent regulation of smooth muscle contractile elements. Am J Physiol 1992; 262:C405-10
13. 2+ senstivity in α-toxin permeabilized arterial smooth muscle. Biochem Biophys Res Commun 1988; 157:677-83
14. 2+ sensitivity. Can J Physiol Pharmacol 1994; 72:1420-6
15. Fujiwara T, Itoh T, Kuhbta Y, Kuriyama H: Effects of guanosine nucleotides on skinned smooth muscle tissue of the rabbit mesenteric artery. J Phsiol (London) 1989; 408:535-47
16. 2+ sensitization of skinned muscle of guinea pig vas deferens. J Pharmacol Exp Ther 1995; 274:555-61
17. 2+ responsiveness of smooth muscle contraction. FEBS Lett 1993; 324:211-5
18. Pfitzer G, Boels PJ: Differential skinning of smooth muscle: a new approach to excitation-contraction coupling. Blood Vessels 1991; 28:262-7
19. 2+- sensitivity in rabbit arterial skinned muscle. Br J Pharmacol 1994; 111:311-7
20. 2+ mobilization and contraction in the porcine coronary artery. J Physiol (London) 1988; 397:401-19
21. Sato K, Leposavic R, Publicover NG, Sanders KM, Gerthoffer WT: Sensitization of the contractile system of canine colonic smooth muscle by agonists and phorbol ester. J Physiol (London) 1994; 481:677-88
22. Nishimura J, van Breemen C: Direct regulation of smooth muscle contractile elemets by second messengers. Biochem Biophys Res Commun 1989; 163:929-35
23. 21+ release in smooth muscle. Physiological role of inositoil 1,4,5-triphosphate in pharrnacomechanical coupling. J Biol Chem 1989; 264:17997-18004
24. Fabiato A, Fabiato F: Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J Physiol Paris 1979; 75:463-505
25. Franks NP, Lieb WR: Temperature dependence of the potency of volatile general anesthetics. ANESTHESIOLOGY 1996; 84:716-20
26. Itoh T, Kanmura Y, Kuriyama H: inorganic phosphate regulates the contraction-relaxation cycle in skinned muscles of the rabbit mesenteric artery. J Physiol (London) 1986; 376:231-52
27. 14C-labeled halothane in isolated perfused rat livers. ANESTHESIOLOGY 1973; 38:328-32
28. Meddings JB, Scott RB, Fick GH: Analysis and comparison of sigmoidal curves: application to dose-response data. Am J Physiol 1989; 257:G982-9
29. Brichant J-F, Warner DO, Gunst SJ, Rehder K: Muscarinic receptor subtypes in canine trachea. Am J Physiol 1990; 258:L349-54
30. Kobayashi S, Somlyo AP, Somlyo AV: Guanine nucleotide- and inositol 1,4,5-trisphosphate-induced calcium release in rabbit main pulmonary artery. J Physiol (London) 1988; 601-19
31. 2+ sensitivity in α-toxin-permeabilized rabbit mesenteric artery. Circ Res 1992; 71:951-9
32. Noda M, Yasuda-Fukazawa C, Moriishi K, Kato T, Okuila T, Kurokawa K, Takuwa Y: Involvement of rho in GTPγS-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity. FEBS Lett 1995; 367:246-50
33. 2+ in α-toxin-permeabilized smooth muscle cells from the guinea-pig stomach. Br J Pharmacol 1992; 107:908-9
34. Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258:607-13
35. 2+-sensitivity and of the time course of contraction in smooth muscle: a major role of protein phosphatases? Adv Prot Phosphatases 1989; 5:181-95
36. Blumberg PM, Jaken S, Konig B, Sharkey NA, Leach KL, Jeng AY, Yeh E: Mechanism of action of the phorbol ester tumor promoters: specific receptors for lipophilic ligands. Biochem Pharmacol 1984; 33:933-40
37. Walsh MP, Andrea JE, Allen BG, Clément-Chomienne O, Collins EM, Morgan KG: Smooth muscle protein kinase C. Can J Physiol Pharmacol 1994; 72:1392-9
38. Schmidt U, Schwinger RH, Bohm M: Interaction of halothane with inhibitory G-proteins in the human myocardium. ANESTHESIOLOGY 1995; 83:353-60
39. Morimoto N, Yamamoto K, Jones KA, Warner DO: Halothane and pertussis toxin-sensitive G proteins in airway smooth muscle. Anesth Analg 1994; 78:328-34
40. Durieux ME: Halothane inhibits signaling through m1 muscarinic receptors expressed in Xenopus oocytes. ANESTHESIOLOGY 1995; 82:174-82
41. Hemnings HC Jr, Adamo AI: Effects halothane and propofol on purified brain protein kinase C activation. ANESTHESIOLOGY 1994; 81:147-55
42. Slater SJ, Cox KJ, Lombardi JV, Ho C, Kelly MB, Rubin E, Stubbs CD: Inhibition of protein kinase C by alcohols and anesthetics. Nature 1993; 364:82-4
43. 2+ mobilization in cultured imnortalized vascular smooth muscle cells. ANESTHESIOLOGY 1994; 80:1102-13