The commercial-scale production of oligonucleotides

Current Opinion in Drug Discovery and Development

Volumn 2, Issue 6, 1999, Pages 578-589

  Zhang, Zhaoda ^a   Tang, Jin Yan ^b  

^a EPIX Medical Inc   (United States)

^b HYBRIDON INC   (United States)

Author keywords

Automated synthesis; Oligonucleotide; Purification; Scale up; Sulfurization

Indexed keywords

ABETIMUS; ALICAFORSEN; ANGIOZYME; CGP 69846A; CYCLIC GMP; ESTER DERIVATIVE; FOMIVIRSEN; GENE EXPRESSION MODULATOR 132; GENE EXPRESSION MODULATOR 231; GENE EXPRESSION MODULATOR 92; GPI 2A; HYDROXYL GROUP; INX 3001; INX 4437; ISIS 13312; ISIS 2503; ISIS 3521; ISIS 5320; MG 98; NUCLEOSIDE DERIVATIVE; OBLIMERSEN; OL(1)P53; OLIGONUCLEOTIDE; PHOSPHONIC ACID DERIVATIVE; PHOSPHOROTHIOIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; R 95288; REAGENT; RIBOZYME; UNCLASSIFIED DRUG; ZINTEVIR;

CHEMICAL REACTION; DRUG MANUFACTURE; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; REVIEW;

EID: 0032735202     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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