Structure of the Xenopus laevis TFF-gene xP4.1, differentially expressed to its duplicated homolog xP4.2

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1489, Issue 2-3, 1999, Pages 345-353

  Botzler, Claus ^a   Oertel, Martin ^b   Hinz, Margitta ^b   Hoffmann, Werner ^b  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Esophagus; Mucin; Mucous neck cell; Promoter; Stomach; TFF domain; Xenopus laevis (Anura)

Indexed keywords

COMPLEMENTARY DNA; HEPATOCYTE NUCLEAR FACTOR 3; PEPTIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TREFOIL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; ESOPHAGUS; EXON; GENE EXPRESSION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ORGANIZATION; GENETIC TRANSCRIPTION; INTRON; MUCOSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH; STOMACH ANTRUM; TATA BOX; TISSUE SPECIFICITY; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; GROWTH SUBSTANCES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RNA, MESSENGER; XENOPUS LAEVIS; XENOPUS PROTEINS;

AMPHIBIA; ANURA; LOTUS; MAMMALIA; XENOPUS LAEVIS;

EID: 0032733908     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(99)00185-2     Document Type: Article

References (44)

1. Wright N.A., Hoffmann W., Otto W.R., Rio M.-C., Thim L. Rolling in the clover: the trefoil factor family (TFF)-domain peptides, cell migration and cancer. FEBS Lett. 408:1997;121-123.
2. Hoffmann W., Hauser F. The P-domain or trefoil motif: a role in renewal and pathology of mucous epithelia? Trends Biochem. Sci. 18:1993;239-243.
3. Wiede A., Jagla W., Welte T., Köhnlein T., Busk H., Hoffmann W. Localization of TFF3, a new mucus-associated peptide of the human respiratory tract. Am. J. Respir. Crit. Care Med. 159:1999;1330-1335.
4. Langer G., Jagla W., Behrens-Baumann W., Walter S., Hoffmann W. Secretory peptides TFF1 and TFF3 synthesized in human conjunctival goblet cells. Invest. Ophthalmol. Vis. Sci. 40:1999;2220-2224.
5. Jagla W., Wiede A., Hinz M., Dietzmann K., Gülicher D., Gerlach K.L., Hoffmann W. Secretion of TFF-peptides by human salivary glands. Cell Tissue Res. 298:1999;161-166.
6. Dignass A., Lynch-Denaney K., Kindon H., Thim L., Podolsky D.K. Trefoil peptides promote epithelial migration through a transforming growth factor β-independent pathway. J. Clin. Invest. 94:1994;376-383.
7. Playford R.J., Marchbank T., Chinery R., Evison R., Pignatelli M., Boulton R.A., Thim L., Hanby A.M. Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology. 108:1995;108-116.
8. Marchbank T., Westley B.R., May F.E.B., Calnan D.P., Playford R.J. Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects. J. Pathol. 185:1998;153-158.
9. Podolsky D.K. Healing the epithelium: solving the problem from two sides. J. Gastroenterol. 32:1997;122-126.
10. Poulsom R., Begos D.E., Modlin I.M. Molecular aspects of restitution: functions of trefoil peptides. Yale J. Biol. Med. 69:1996;137-146.
11. Lefebvre O., Chenard M.-P., Masson R., Linares J., Dierich A., LeMeur M., Wendling C., Tomasetto C., Chambon P., Rio M.-C. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science. 274:1996;259-262.
12. Mashimo H., Wu D.-C., Podolsky D.K., Fishman M.C. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science. 274:1996;262-265.
13. Hauser F., Hoffmann W. xP1 and xP4: P-domain peptides expressed in Xenopus laevis stomach mucosa. J. Biol. Chem. 266:1991;21306-21309.
14. Jagla W., Wiede A., Kölle S., Hoffmann W. Differential expression of the TFF-peptides xP1 and xP4 in the gastrointestinal tract of Xenopus laevis. Cell Tissue Res. 291:1998;13-18.
15. Probst J.C., Hauser F., Joba W., Hoffmann W. The polymorphic integumentary mucin B.1 from Xenopus laevis contains the short consensus repeat. J. Biol. Chem. 267:1992;6310-6316.
16. Joba W., Hoffmann W. Alternative splicing of repetitive units is responsible for the polydispersities of integumentary mucin B.1 (FIM-B.1) from Xenopus laevis. Glycoconjugate J. 13:1996;735-740.
17. Rinder H., Bayer T.A., Gertzen E.-M., Hoffmann W. Molecular analysis of the ependymin gene and functional test of its promoter region by transient expression in Brachydanio rerio. DNA Cell Biol. 11:1992;425-432.
18. Quandt K., Frech K., Karas H., Wingender E., Werner T. MatInd and MatInspector - new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:1995;4878-4884.
19. Breathnach R., Chambon P. Organization and expression of eucaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:1981;349-383.
20. Patthy L. Intron-dependent evolution: preferred types of exons and introns. FEBS Lett. 214:1987;1-7.
21. Long M., Rosenberg C., Gilbert W. Intron phase correlations and the evolution of the intron/exon structure of genes. Proc. Natl. Acad. Sci. USA. 92:1995;12495-12499.
22. Jeltsch J.M., Roberts M., Schatz C., Garnier J.M., Brown A.M.C., Chambon P. Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res. 15:1987;1401-1414.
23. Gött P., Beck S., Machado J.C., Carneiro F., Schmitt H., Blin N. Human trefoil peptides: genomic structure in 21q22.3 and coordinated expression. Eur. J. Hum. Genet. 4:1996;308-315.
24. Seib T., Dooley S., Welter C. Characterization of the genomic structure and the promoter region of the human intestinal trefoil factor. Biochem. Biophys. Res. Commun. 214:1995;195-199.
25. Sands B.E., Ogata H., Lynch-Devaney K., deBeaumont M., Ezzell R.M., Podolsky D.K. Molecular cloning of the rat intestinal trefoil factor gene: characterization of an intestinal goblet cell-associated promoter. J. Biol. Chem. 270:1995;9353-9361.
26. Mashimo H., Podolsky D.K., Fishman M.C. Structure and expression of murine intestinal trefoil factor: high evolutionary conservation and postnatal expression. Biochem. Biophys. Res. Commun. 210:1995;31-37.
27. Chinery R., Poulsom R., Cox H.M. The gene encoding mouse intestinal trefoil factor: structural organization, partial sequence analysis and mapping to murine chromosome 17q. Gene. 171:1996;249-253.
28. Harris J.D., Hibler D.W., Fontenot G.K., Hsu K.T., Yurewicz E.C., Sacco A.G. Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families. DNA Sequence. 4:1994;361-393.
29. Hauser F., Roeben C., Hoffmann W. xP2, a new member of the P-domain peptide family of potential growth factors, is synthesized in Xenopus laevis skin. J. Biol. Chem. 267:1992;14451-14455.
30. Hauser F., Hoffmann W. P-domains as shuffled cysteine-rich modules in integumentary mucin C.1 (FIM-C.1) from Xenopus laevis. J. Biol. Chem. 267:1992;24620-24624.
31. Hromas R., Costa R. The hepatocyte nuclear factor 3/forkhead transcription regulatory family in development, inflammation and neoplasia. Crit. Rev. Oncol. Hematol. 20:1995;129-140.
32. Beck S., Sommer P., dos Santos Silva E., Blin N., Gött P. Hepatocyte nuclear factor 3 (winged helix domain) activates trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box. DNA Cell Biol. 18:1999;157-164.
33. Beck S., Sommer P., Blin N., Gött P. 5′-Flanking motifs control cell-specific expression of trefoil factor genes (TFF). Int. J. Mol. Med. 2:1998;353-361.
34. Nunez A.-M., Berry M., Imler J.-L., Chambon P. The 5′ flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumor promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein. EMBO J. 8:1989;823-829.
35. Berry M., Nunez A.-M., Chambon P. Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence. Proc. Natl. Acad. Sci. USA. 86:1989;1218-1222.
36. Angel P., Karin M. The role of jun, fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta. 1072:1991;129-157.
37. Gillesby B.E., Stanostefano M., Porter W., Safe S., Wu Z.F., Zacharewski T.R. Identification of a motif within the 5′-regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated suppression. Biochemistry. 36:1997;6080-6089.
38. Lee W., Mitchell P., Tjian R. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell. 49:1987;741-752.
39. Quantin B., Breathnach R. Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts. Nature. 334:1988;538-539.
40. Thiébaud C.H., Fischberg M. DNA content in the genus Xenopus. Chromosoma (Berl.). 59:1977;253-257.
41. Kobel H.R., Du Pasquier L. Genetics of polyploid Xenopus. Trends Genet. 2:1986;310-315.
42. Bisbee C.A., Baker M.A., Wilson A.C., Hadji-Azimi I., Fischberg M. Albumin phylogeny for clawed frogs (Xenopus). Science. 195:1977;785-787.
43. Scales J.B., Olson E.N. Differential expression of two distinct MyoD genes in Xenopus. Cell Growth Differ. 2:1991;619-629.
44. Gervasi C., Szaro B.G. Sequence and expression patterns of two forms of the middle molecular weight neurofilament protein (NF-M) of Xenopus laevis. Brain Res. Mol. Brain Res. 48:1997;229-242.