-
1
-
-
0028939301
-
Multiple canalicular transport mechanisms for glutathione S-conjugates: Transport on both ATP- and voltage-dependent carriers
-
Ballatori N and Truong AT (1995) Multiple canalicular transport mechanisms for glutathione S-conjugates: Transport on both ATP- and voltage-dependent carriers. J Biol Chem 270:3594-3601.
-
(1995)
J Biol Chem
, vol.270
, pp. 3594-3601
-
-
Ballatori, N.1
Truong, A.T.2
-
2
-
-
0023146745
-
Effect of phenobarbital on the distribution of drug metabolizing enzymes between periportal and perivenous rat hepatocytes prepared by digitonin-collagenase liver perfusion
-
Bengtsson G, Julkunen A, Penttilä KE and Lindros KO (1987) Effect of phenobarbital on the distribution of drug metabolizing enzymes between periportal and perivenous rat hepatocytes prepared by digitonin-collagenase liver perfusion. J Pharmacol Exp Ther 240:663-667.
-
(1987)
J Pharmacol Exp Ther
, vol.240
, pp. 663-667
-
-
Bengtsson, G.1
Julkunen, A.2
Penttilä, K.E.3
Lindros, K.O.4
-
3
-
-
0040761368
-
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
Büchler M, König J, Brom M, Kartenbeck J, Spring H, Horie T and Keppler D (1996) cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J Biol Chem 271:15091-15098.
-
(1996)
J Biol Chem
, vol.271
, pp. 15091-15098
-
-
Büchler, M.1
König, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
Keppler, D.7
-
4
-
-
0024531649
-
Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/ collagenase perfusion
-
Burger H-J, Gebhardt R, Mayer C and Mecke D (1989) Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/ collagenase perfusion. Hepatology 9:22-28.
-
(1989)
Hepatology
, vol.9
, pp. 22-28
-
-
Burger, H.-J.1
Gebhardt, R.2
Mayer, C.3
Mecke, D.4
-
5
-
-
0001308329
-
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
-
Evers R, Kool M, van Deemter L, Janssen H, Calafat J, Oomen LCJM, Paulusma CC, Oude Elferink RPJ, Bass F, Schinkel AH and Borst P (1998) Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. J Clin Invest 101:1310-1319.
-
(1998)
J Clin Invest
, vol.101
, pp. 1310-1319
-
-
Evers, R.1
Kool, M.2
Van Deemter, L.3
Janssen, H.4
Calafat, J.5
Lcjm, O.6
Paulusma, C.C.7
Oude Elferink, R.P.J.8
Bass, F.9
Schinkel, A.H.10
Borst, P.11
-
6
-
-
0023079953
-
High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives
-
Fariss MW and Reed DJ (1987) High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives. Methods Enzymol 143:101-109.
-
(1987)
Methods Enzymol
, vol.143
, pp. 101-109
-
-
Fariss, M.W.1
Reed, D.J.2
-
7
-
-
0016275313
-
Glutathione S-transferases: The first enzymatic step in mercapturic acid formation
-
Habig WH, Pabst MJ and Jakoby WB (1974) Glutathione S-transferases: The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139.
-
(1974)
J Biol Chem
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
8
-
-
0031866357
-
Hepatic expression of multidrug resistance-associated protein-like proteins maintained in Eisai hyperbilirubinemic rats
-
Hirohashi T, Suzuki H, Ito K, Ogawa K, Kume K, Shimizu T and Sugiyama Y (1998) Hepatic expression of multidrug resistance-associated protein-like proteins maintained in Eisai hyperbilirubinemic rats. Mol Pharmacol 53:1068-1075.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 1068-1075
-
-
Hirohashi, T.1
Suzuki, H.2
Ito, K.3
Ogawa, K.4
Kume, K.5
Shimizu, T.6
Sugiyama, Y.7
-
9
-
-
0029993507
-
Bumetanide is not transported by the Ntcp or by the oatp: Evidence for a third organic anion transporter in rat liver cells
-
Horz JA, Honscha W and Petzinger E (1996) Bumetanide is not transported by the Ntcp or by the oatp: Evidence for a third organic anion transporter in rat liver cells. Biochim Biophys Acta 1300:114-118.
-
(1996)
Biochim Biophys Acta
, vol.1300
, pp. 114-118
-
-
Horz, J.A.1
Honscha, W.2
Petzinger, E.3
-
10
-
-
0033054241
-
Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2)
-
Kakyo M, Sakagami H, Nishio T, Nakai D, Nakagomi R, Tokui T, Naitoh T, Matsuno S, Abe T and Yawo H (1999) Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2). FEBS Lett 445:343-346.
-
(1999)
FEBS Lett
, vol.445
, pp. 343-346
-
-
Kakyo, M.1
Sakagami, H.2
Nishio, T.3
Nakai, D.4
Nakagomi, R.5
Tokui, T.6
Naitoh, T.7
Matsuno, S.8
Abe, T.9
Yawo, H.10
-
11
-
-
17144465167
-
ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2
-
Keppler D, Leier I, Jedlitschky G and König J (1998) ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2. Chem-Biol Interact 111-112:153-161.
-
(1998)
Chem-biol Interact
, vol.111-112
, pp. 153-161
-
-
Keppler, D.1
Leier, I.2
Jedlitschky, G.3
König, J.4
-
12
-
-
0023248470
-
Acinar distribution of glutathione-dependent detoxifying enzymes: Low glutathione peroxidase activity in perivenous hepatocytes
-
Kera Y, Sippel HW, Penttïla KE and Lindros KO (1987) Acinar distribution of glutathione-dependent detoxifying enzymes: Low glutathione peroxidase activity in perivenous hepatocytes. Biochem Pharmacol 36:2003-2006.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 2003-2006
-
-
Kera, Y.1
Sippel, H.W.2
Penttïla, K.E.3
Lindros, K.O.4
-
13
-
-
0032926354
-
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
-
König J, Rost D, Cui Y and Keppler D (1999) Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 29:1156-1163.
-
(1999)
Hepatology
, vol.29
, pp. 1156-1163
-
-
König, J.1
Rost, D.2
Cui, Y.3
Keppler, D.4
-
14
-
-
13044294031
-
MRP3, an organic anion transporter able to transport anti-cancer drugs
-
Kool M, van der Linden M, de Haas M, Scheffer GL, de Vree JML, Smith AJ, Jansen G, Peters GJ, Ponne N, Scheper RJ, Oude Elferink RPJ, Baas F and Borst P (1999) MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Natl Acad Sci USA 96:6914-6919.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6914-6919
-
-
Kool, M.1
Van Der Linden, M.2
De Haas, M.3
Scheffer, G.L.4
De Vree, J.M.L.5
Smith, A.J.6
Jansen, G.7
Peters, G.J.8
Ponne, N.9
Scheper, R.J.10
Oude Elferink, R.P.J.11
Baas, F.12
Borst, P.13
-
15
-
-
0031011842
-
Membrane transport in hepatic clearance of drugs iI: Zonal distribution patterns of concentration-dependent transport and elimination processes
-
Kwon Y and Morris ME (1997) Membrane transport in hepatic clearance of drugs II: Zonal distribution patterns of concentration-dependent transport and elimination processes. Pharm Res 14:780-785.
-
(1997)
Pharm Res
, vol.14
, pp. 780-785
-
-
Kwon, Y.1
Morris, M.E.2
-
16
-
-
0028258561
-
Cellular sources of glutathione S-transferase P in primary cultured rat hepatocytes: Localization by in situ hybridization
-
Lee SJ, Friedman SL, Whalen R and Boyer TD (1994) Cellular sources of glutathione S-transferase P in primary cultured rat hepatocytes: Localization by in situ hybridization. Biochem J 299:79-83.
-
(1994)
Biochem J
, vol.299
, pp. 79-83
-
-
Lee, S.J.1
Friedman, S.L.2
Whalen, R.3
Boyer, T.D.4
-
17
-
-
0021801314
-
Digitonin-collagenase perfusion for efficient separation of periportal or perivenous hepatocytes
-
Lindros KO and Pentïlla KE (1985) Digitonin-collagenase perfusion for efficient separation of periportal or perivenous hepatocytes. Biochem J 228:757-760.
-
(1985)
Biochem J
, vol.228
, pp. 757-760
-
-
Lindros, K.O.1
Pentïlla, K.E.2
-
18
-
-
0032519657
-
Aryl hydrocarbon receptor-associated genes in rat liver: Regional coinduction of aldehyde dehydrogenase 3 and glutathione transferase Ya
-
Lindros KO, Oinonen T, Kettunen E, Sippel H, Muro-Lupori C and Koivusalo M (1998) Aryl hydrocarbon receptor-associated genes in rat liver: Regional coinduction of aldehyde dehydrogenase 3 and glutathione transferase Ya. Biochem Pharmacol 58:413-421.
-
(1998)
Biochem Pharmacol
, vol.58
, pp. 413-421
-
-
Lindros, K.O.1
Oinonen, T.2
Kettunen, E.3
Sippel, H.4
Muro-Lupori, C.5
Koivusalo, M.6
-
20
-
-
0025738538
-
Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat
-
Lu SC, Kuhlenkamp J, Garcia-Ruiz C and Kaplowitz N (1991) Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat. J Clin Invest 88:260-269.
-
(1991)
J Clin Invest
, vol.88
, pp. 260-269
-
-
Lu, S.C.1
Kuhlenkamp, J.2
Garcia-Ruiz, C.3
Kaplowitz, N.4
-
21
-
-
0029790153
-
The distribution of theta-class glutathione S-transferasea in the liver and lung of mouse, rat and human
-
Mainwaring GW, Williams SM, Foster JR, Tugwood J and Green T (1996) The distribution of theta-class glutathione S-transferasea in the liver and lung of mouse, rat and human. Biochem J 318:297-303.
-
(1996)
Biochem J
, vol.318
, pp. 297-303
-
-
Mainwaring, G.W.1
Williams, S.M.2
Foster, J.R.3
Tugwood, J.4
Green, T.5
-
22
-
-
0032581363
-
Membrane localization of the electrogenic cation transporter rOCT1 in rat liver
-
Meyer-Wentrup F, Karbach U, Gorboulev V, Arndt P and Koepsell H (1998) Membrane localization of the electrogenic cation transporter rOCT1 in rat liver. Biochem Biophys Res Commun 248:673-678.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 673-678
-
-
Meyer-Wentrup, F.1
Karbach, U.2
Gorboulev, V.3
Arndt, P.4
Koepsell, H.5
-
23
-
-
0027056957
-
+-dicarboxylate cotransport: Identification, characterization, and acinar localization
-
+-dicarboxylate cotransport: identification, characterization, and acinar localization. Am J Physiol 263:G871-G879.
-
(1992)
Am J Physiol
, vol.263
-
-
Moseley, R.H.1
Jarose, S.2
Permoad, P.3
-
24
-
-
0032531814
-
Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoricities of ethacrynic acid but not oxazaphosphorines or cisplatin
-
Morrow CS, Smitherman PK and Townsend AJ (1998) Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoricities of ethacrynic acid but not oxazaphosphorines or cisplatin. Biochem Pharmacol 56: 1013-1022.
-
(1998)
Biochem Pharmacol
, vol.56
, pp. 1013-1022
-
-
Morrow, C.S.1
Smitherman, P.K.2
Townsend, A.J.3
-
25
-
-
0027480216
-
Accumulation of organic anion in intracellular vesicles of cultured rat hepatocytes is mediated by the canalicular multispecific organic anion transporter
-
Oude Elferink RPJ, Bakker CTM, Roelofsen H, Middelkoop E, Ottenhoff R, Heijn M and Jansen PLM (1993) Accumulation of organic anion in intracellular vesicles of cultured rat hepatocytes is mediated by the canalicular multispecific organic anion transporter. Hepatology 17:434-444.
-
(1993)
Hepatology
, vol.17
, pp. 434-444
-
-
Oude Elferink, R.P.J.1
Bakker, C.T.M.2
Roelofsen, H.3
Middelkoop, E.4
Ottenhoff, R.5
Heijn, M.6
Jansen, P.L.M.7
-
26
-
-
0029002206
-
Acinar factors in drug processing: Protein binding, futile cycling and cosubstrate
-
Pang KS (1995) Acinar factors in drug processing: protein binding, futile cycling and cosubstrate. Drug Metab Rev 27:325-368.
-
(1995)
Drug Metab Rev
, vol.27
, pp. 325-368
-
-
Pang, K.S.1
-
27
-
-
0027238833
-
Constitutive and inducible profile of glutathione S-transferase subunits in biliary epithelial cells and hepatocytes isolated from rat liver
-
Parola M, Biocca ME, Leonarduzzi G, Albano E, Dianzani MU, Gilmore KS, Meyer DJ, Ketterer B, Slater TF and Cheeseman KH (1993) Constitutive and inducible profile of glutathione S-transferase subunits in biliary epithelial cells and hepatocytes isolated from rat liver. Biochem J 291:641-647.
-
(1993)
Biochem J
, vol.291
, pp. 641-647
-
-
Parola, M.1
Biocca, M.E.2
Leonarduzzi, G.3
Albano, E.4
Dianzani, M.U.5
Gilmore, K.S.6
Meyer, D.J.7
Ketterer, B.8
Slater, T.F.9
Cheeseman, K.H.10
-
28
-
-
0027379537
-
Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases
-
Ploemen JHTM, Van Ommen B, Bogaards JJP and Van Bladeren PJ (1993) Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases. Xenobiotica 23:913-923.
-
(1993)
Xenobiotica
, vol.23
, pp. 913-923
-
-
Ploemen, J.H.T.M.1
Van Ommen, B.2
Bogaards, J.J.P.3
Van Bladeren, P.J.4
-
29
-
-
0025150771
-
Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate
-
Ploemen JHTM, Van Ommen B and Van Bladeren PJ (1990) Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate. Biochem Pharmacol 40:1631-1635.
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 1631-1635
-
-
Ploemen, J.H.T.M.1
Van Ommen, B.2
Van Bladeren, P.J.3
-
30
-
-
0028209437
-
Reversible conjugation of ethacrynic acid with glutathione and human glutathione s-transferase p1-i
-
Ploemen JHTM, Van Schanke A, Van Ommen B and Van Bladeren PJ (1994) Reversible conjugation of ethacrynic acid with glutathione and human glutathione S-transferase P1-I. Cancer Res 54:915-919.
-
(1994)
Cancer Res
, vol.54
, pp. 915-919
-
-
Ploemen, J.H.T.M.1
Van Schanke, A.2
Van Ommen, B.3
Van Bladeren, P.J.4
-
31
-
-
0023132394
-
Dual-digitonin-pulse perfusion: Concurrent sampling of periportal and perivenous cytosol of rat liver for determination of metab olites and enzyme activities
-
Quistorff B and Grunnet N (1987) Dual-digitonin-pulse perfusion: Concurrent sampling of periportal and perivenous cytosol of rat liver for determination of metab olites and enzyme activities. Biochem J 243:87-95.
-
(1987)
Biochem J
, vol.243
, pp. 87-95
-
-
Quistorff, B.1
Grunnet, N.2
-
32
-
-
0020491456
-
Immunohistochemical localization of glutathione S-transferases in livers of untreated rats
-
Redick JA, Jakoby WB and Baron J (1982) Immunohistochemical localization of glutathione S-transferases in livers of untreated rats. J Biol Chem 257:15200-15203.
-
(1982)
J Biol Chem
, vol.257
, pp. 15200-15203
-
-
Redick, J.A.1
Jakoby, W.B.2
Baron, J.3
-
33
-
-
0029070075
-
Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes
-
Roelofsen H, Bakker CTM, Schoemaker B, Heijn M, Jansen PLM and Oude Elferink RPJ (1995) Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes. Hepatology 21:1649-1657.
-
(1995)
Hepatology
, vol.21
, pp. 1649-1657
-
-
Roelofsen, H.1
Bakker, C.T.M.2
Schoemaker, B.3
Heijn, M.4
Jansen, P.L.M.5
Oude Elferink, R.P.J.6
-
34
-
-
0026595561
-
Zonal distribution of cysteine uptake in the perfused rat liver
-
Saiki H, Chan ET, Wong E, Yamamuro W, Ookhtens M and Kaplowitz N (1992) Zonal distribution of cysteine uptake in the perfused rat liver. J Biol Chem 267:192-196.
-
(1992)
J Biol Chem
, vol.267
, pp. 192-196
-
-
Saiki, H.1
Chan, E.T.2
Wong, E.3
Yamamuro, W.4
Ookhtens, M.5
Kaplowitz, N.6
-
35
-
-
0028920506
-
The high non-enzymatic conjugation rates of some glutathione S-transferase (GST) substrates at high glutathione concentrations
-
Satoh K (1995) The high non-enzymatic conjugation rates of some glutathione S-transferase (GST) substrates at high glutathione concentrations. Carcinogenesis 16:869-874.
-
(1995)
Carcinogenesis
, vol.16
, pp. 869-874
-
-
Satoh, K.1
-
36
-
-
0029835925
-
Distribution of glutathione S-transferase isoforms in rat liver after induction by β-naphthoflavone or 3-methyl-cholanthrene
-
Sippel H, Lindros KO and Oinonen T (1996) Distribution of glutathione S-transferase isoforms in rat liver after induction by β-naphthoflavone or 3-methyl-cholanthrene. Pharmacol Toxicol 79:80-86.
-
(1996)
Pharmacol Toxicol
, vol.79
, pp. 80-86
-
-
Sippel, H.1
Lindros, K.O.2
Oinonen, T.3
-
37
-
-
0024788818
-
The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells
-
Steinberg P, Schramm H, Schladt L, Robertson LW, Thomas H and Oesch F (1989) The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells. Biochem J 264:737-744.
-
(1989)
Biochem J
, vol.264
, pp. 737-744
-
-
Steinberg, P.1
Schramm, H.2
Schladt, L.3
Robertson, L.W.4
Thomas, H.5
Oesch, F.6
-
39
-
-
0024507027
-
Drug metabolism by periportal and perivenous rat hepatocytes: Comparison of phase I and phase II reactions and their inducibility during culture
-
Suolinna E-M, Penttiẍla KE, Winell B-M, Sjõholm A-C and Lindros KO (1989) Drug metabolism by periportal and perivenous rat hepatocytes: Comparison of phase I and phase II reactions and their inducibility during culture. Biochem Pharmacol 38:1329-1334.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 1329-1334
-
-
Suolinna, E.-M.1
Penttiẍla, K.E.2
Winell, B.-M.3
Sjõholm, A.-C.4
Lindros, K.O.5
-
40
-
-
0025027463
-
Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats: Modulation by glucose
-
Tal M, Schneider DL, Thorens B and Lodish HF (1990) Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats: modulation by glucose. J Clin Invest 86:986-992.
-
(1990)
J Clin Invest
, vol.86
, pp. 986-992
-
-
Tal, M.1
Schneider, D.L.2
Thorens, B.3
Lodish, H.F.4
-
41
-
-
0032943219
-
Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes
-
Tan E, Tirona RG and Pang KS (1999) Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes. Drug Metab Dispos 27:336-341.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 336-341
-
-
Tan, E.1
Tirona, R.G.2
Pang, K.S.3
-
42
-
-
0032774131
-
Bimolecular glutathione conjugation kinetics of ethacrynic acid in rat liver: In vitro and perfusion studies
-
Tirona RG and Pang KS (1999) Bimolecular glutathione conjugation kinetics of ethacrynic acid in rat liver: In vitro and perfusion studies. J Pharmacol Exp Ther 290:1230-1241.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 1230-1241
-
-
Tirona, R.G.1
Pang, K.S.2
-
43
-
-
0030570805
-
Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP
-
Zaman GJR, Cnubben NHP, van Bladeren PJ, Evers R and Borst P (1996) Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP. FEBS Lett 391:126-130.
-
(1996)
FEBS Lett
, vol.391
, pp. 126-130
-
-
Zaman, G.J.R.1
Cnubben, N.H.P.2
Van Bladeren, P.J.3
Evers, R.4
Borst, P.5
|