Membrane transport in hepatic clearance of drugs. II: Zonal distribution patterns of concentration-dependent transport and elimination processes

Pharmaceutical Research

Volumn 14, Issue 6, 1997, Pages 780-785

  Kwon, Younggil ^a,b   Morris, Marilyn E ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b PFIZER INC   (United States)

Author keywords

Blood and tissue concentration gradient profiles; Nonlinear intrinsic elimination; Nonlinear transport; Pharmacokinetic models; Zonal distribution

Indexed keywords

CARRIER PROTEIN;

ARTICLE; COMPUTER SIMULATION; DIFFUSION; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG TRANSPORT; LIVER BLOOD FLOW; LIVER CELL; LIVER CLEARANCE; MODEL; PHARMACOKINETICS; PRIORITY JOURNAL;

BIOLOGICAL TRANSPORT; BLOOD PROTEINS; CARRIER PROTEINS; CELL MEMBRANE; LIVER; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PROTEIN BINDING;

EID: 0031011842     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012158607766     Document Type: Article

References (30)

1. J. J. Gumucio. Hepatology 9(1):154-160 (1989).
2. N. Katz and K. Jungermann. In "Hepatic transport and bile secretion: physiology and pathology" (N. Tavoloni and P. D. Berk, eds), Raven Press Ltd., New York, pp. 55-70 (1993).
3. K. Jungermann and N. Katz. Phvsiol. Rev. 69:708-764(1989).
4. B. Quistorff. Essays Biochem. 25:83-136 (1990).
5. J. J. Gumucio and E. E. Guibert. In "Hepatic transport and bile secretion: physiology and pathology" (N. Tavoloni and P. D. Berk, eds), Raven Press Ltd., New York, pp. 71-82 (1993).
6. G. M. M. Groothuis and D. K. F. Meijer. Enzyme 46:94-138 (1992).
7. H. J. Burger, R. Gebhardt, C. Mayer, and D. Mecke. Hepatology. 9(1):22-28 (1989).
8. G. M. M. Groothuis, K. P. T. Keulemans, M. J. Hardonk, and D. K. F. Meijer. Biochem. Pharmacol. 32(20):3069-3078 (1983).
9. G. M. M. Groothuis, J. G. Weitering, K. P. T. Keulemans, M. J. Hardonk, D. Mulder, and D. K. F. Meijer. Naunyn-Schmiedeberg's Arch. Pharmacol. 322:310-318 (1983).
10. H. Saiki, E. T. Chan, E. Wong, W. Yamamuro, M. Ookhtens, and N. Kaplowitz. J. Biol. Chem. 267:192-196 (1992).
11. I. Braakman, G. M. M. Groothuis, and D. K. F. Meijer. Hepatology. 7(5):849-855 (1987).
12. J. J. Gumucio, D. L. Miller, M. D. Krauss, and C. C. Zanolli. Gastroenterology. 80:639-646 (1981).
13. P. V. D. Sluijs, I. Braakman, D. K. F. Meijer, and G. M. M. Groothuis. Hepatology. 8(6):1521-1529 (1988).
14. C. A. Goresky, G. G. Bach, and C. P. Rose. Am. J. Physiol. 244:G215-G232 (1983).
15. H. Sato, Y. Sugiyama, S. Miyauchi, Y. Sawada, T. Iga, and M. Hanano. J. Pharm. Sci. 75(1):3-8 (1986).
16. M. E. Morris and K. S. Pang. J. Pharmacokin. Biopharm. 15(5):473-496 (1987).
17. M. E. Morris, V. Yuen, and K. S. Pang. J. Pharmacokin. Biopharm. 16(6):633-656 (1988).
18. D. K. F. Meijer, W. E. M. Mol, M. Muller, and G. Kurz. J. Pharmacokin. Biopharm. 18:35-70 (1990).
19. R. H. Moseley, S. M. Jarose, and P. Permoad. Am. J. Physiol. 263:G775-G785 (1992).
20. S. Keiding, S. Johansen, K. Winkler, K. Tønnesen, and N. Tygstrup. Am. J. Physiol. 230(5):1302-1313 (1976).
21. J. Reichen and G. Paumgartner. Gastroenterology. 68:132-136 (1975).
22. Y. Kwon and M. E. Morris. Pharm. Res. (companion article).
23. R. B. Hornbeck. In Numerical Methods, Quantum Publishers, Inc., New York, 1975, pp. 185-226.
24. M. Yamazaki, H. Suzuki, and Y. Sugiyami. Pharm. Res. 13:497-513 (1996).
25. K. S. Pang and R. N. Stillwell. J. Pharmacokin. Biopharm. 11:451-468 (1983).
26. I. A. M. de Lannoy and K. S. Pang. Drug. Metab. Dispos. 14:513-520 (1986).
27. I. A. M. DeLannoy and K. S. Pang. Drug Metab. Dispos. 15(1):51-58 (1987).
28. C. A. Goresky, G. G. Bach, and B. E. Nadeau. J. Clin. Invest. 52:975-990 (1973).
29. P. L. Gumucio, J. J. Gumucio, J. A. P. Wilson, C. Cutter, M. Krauss, R. Caldwell, and E. Chen. Am. J. Physiol. 246:G86-G95 (1984).
30. X. Xu, P. Selick, and K. S. Pang. J. Pharmacokin. Biopharm. 21:43-74 (1993).