Expression and characterisation of human and rat CRF(2α) receptors

European Journal of Pharmacology

Volumn 379, Issue 2-3, 1999, Pages 219-227

  Suman Chauhan, Nirmala ^c   Carnell, Pauline ^a   Franks, Ruth ^a   Webdale, Louise ^a   Gee, Nicolas S ^a   McNulty, Shaun ^a   J Rossant, Christine ^a   Van Leeuwen, Don ^b   MacKenzie, Robert ^b   Hall, Matthew D ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER INC   (United States)

^c NONE

Author keywords

125I tyr0 Sauvagine; cAMP; CRF receptor antagonist; CRF(2 ) receptor

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2ALPHA; CYCLIC AMP; HORMONE RECEPTOR; PD 173307; PD 173602; PD 174239; RECEPTOR SUBTYPE; SAUVAGINE; UNCLASSIFIED DRUG; UROCORTIN; UROTENSIN; UROTENSIN I; UROTENSIN II; WHEAT GERM AGGLUTININ;

ANIMAL CELL; ARTICLE; CHO CELL; DRUG RECEPTOR BINDING; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR AFFINITY;

ANIMALS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; HUMANS; MALE; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; VASODILATOR AGENTS;

EID: 0032730263     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00505-1     Document Type: Article

References (29)

1. Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:1987;2745-2752.
2. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:1973;3099.
3. Coskun T., Bozkurt A., Alican I., Ozkultu U., Kurtel H., Yegen C. Pathways mediating CRF-induced inhibition of gastric emptying in rats. Regul. Pept. 69:1997;113-120.
4. De Souza E.B., Whitehouse P.J., Kuhar M.J., Price D.L., Vale W.W. Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease. Nature. 319:1986;593-595.
5. Diamant M., De Wied D. Autonomic and behavioural effects of centrally administered corticotropin-releasing factor in rats. Endocrinology. 129:1991;446-454.
6. Donaldson C.J., Sutton S.W., Perrin M.H., Corrigan A.Z., Lewis K.A., Rivier J.E., Vaughan J.M., Vale W.W. Cloning and characterisation of human urocortin. Endocrinology. 137:1996;2167-2170.
7. 9-41 in three bioassay systems. Endocrinology. 129(3):1991;1312-1316.
8. 2α receptors Mol. Pharmacol. 50:1996;679-686.
9. Heinrichs S.C., Vale E.A., Lapansky J., Behan D.P., McClure L.V., Ling N., De Souza E.B., Schulteis G. Enhancement of performance in multiple learning tasks by corticotropin releasing factor binding protein ligand inhibitors. Peptides. 18(5):1997;711-716.
10. Kostich W.A., Chen A.R., Sperle K., Largent B.L. Molecular identification and analysis of a novel human corticotropin-releasing factor (CRF) receptor: the CRF2 gamma receptor. Mol. Endocrinol. 12(8):1998;1077-1085.
11. Liaw C.W., Lovenberg T.W., Barry G., Oltersdorf T., Grigoriadis D.E., De-Souza E.B. Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid. Endocrinology. 137:1996;72-77.
12. Lovenberg T.W., Chalmers D.T., Liu C., De Souza E.B. CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues. Endocrinology. 136(9):1995;4139-4142.
13. Lovenberg T.W., Liaw C.W., Grigoriadis D.E., Clevenger W., Chalmers D.T., De-Souza E.B., Oltersdorf T. Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain. Proc. Natl. Acad. Sci. U.S.A. 92:1995;836-840.
14. Lowry D.H., Rosebrough D.S., Farr A.L., Randall P.J. Protein measurement with the folin-phenol reagent. J. Biol. Chem. 193:1951;265-275.
15. Meyer A.H., Ullmer C., Schmuck K., Morel C., Wishart W., Lubbert H., Engels P. Localization of the Human CRF2 receptor to 7p21-p15 by radiation hybrid mapping and FISH analysis. Genomics. 40:1997;189-190.
16. Moreau J-L., Kilpatrick G.K., Jenck F. Urocortin, a novel neuropeptide with anxiogenic-like properties. NeuroReport. 8(7):1997;1697-1701.
17. Nemeroff C.B. New vistas in neuropeptide research in neuropsychiatry: Focus on corticotropin-releasing factor. Neuropsychopharmacology. 6(2):1992;69-75.
18. Owens, M.J., Nemeroff, C.B., 1993. In: D.J., Chadwick, D.J., Marsh, T., Ackrill, K. (Eds.), Corticotropin Releasing Factor. Wiley, New York, pp. 296-316.
19. 2 binding sites in adult rat brain. Neuropsychopharmacology. 17(5):1997;308-316.
20. Richter R.M., Mulvany M.J. Comparison of hCRF and oCRF effects on cardiovascular responses after central, peripheral and in vitro application. Peptides. 16(5):1995;843-849.
21. Rivier J., Rivier C., Vale W. Synthetic competitive antagonist of corticotropin releasing factor: effect on ACTH secretion in the rat. Science. 224:1984;889-891.
22. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory.
23. Smart, D., Coppell, A., Rossant, C., Hall, M., McKnight, A., 1999. Characterisation using microphysiometry of corticotropin releasing factor receptor pharmacology, =13,124.
24. Schulz D.W., Mansbach R.S., Sprouse J., Braselton J.P., Collins J., Corman M., Dunaiskis A., Faraci S., Schmidt A.W., Seeger T., Seymour P., Tingley F.D. III, Winston E.N., Chen Y.L., Heym J. CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc. Natl. Acad. Sci. U.S.A. 93:1996;10477-10482.
25. Udenfriend S., Gerber L., Nelson N. Scintillation proximity assay: a sensitive and continuous isotopic method for monitoring ligand/receptor and antigen/antibody interactions. Anal. Biochem. 161:1987;494-500.
26. 2 receptor for corticotropin-releasing factor. Biochim. Biophys. Acta. 1352(2):1997;129-132.
27. Vale W., Spiess J., Rivier C., Rivier J. Characterisation of a 41-residues ovine hypothalamic peptide that stimulates secretion of corticotropin and β-endorphin. Science. 213:1981;1394-1397.
28. Vaughan J., Donaldson C., Bittencourt J., Perrin M.H., Lewis K., Sutton S., Chan R., Turnbull A.V., Lovejoy D., Rivier C., Rivier J., Sawchenko P.E., Vale W. Urocortin, a mammalian neuropeptide related to fish urotensin 1 and to corticotropin-releasing factor. Nature. 378:1995;287-292.
29. Wustrow D.J., Capiris T., Rubin R., Knobelsdorf J.A., Akunne H., Davis M.D., MacKenzie R., Pugsley T.A., Zoski K.T., Heffner T.G., Wise L.D. Pyrazolo[1,5-a]pyrimidine CRF1 receptor antagonists. Bioorg. Med. Chem. Lett. 8:1998;2067-2070.