Screening of protective antigens of Japanese encephalitis virus by DNA immunization: A comparative study with conventional viral vaccines

Journal of Virology

Volumn 73, Issue 12, 1999, Pages 10137-10145

  Chen, Hsin Wei ^a   Pan, Chien Hsiung ^a,b   Liau, Ming Yi ^c   Jou, Ruwen ^c   Tsai, Chiao Jung ^a   Wu, Hsin Jung ^a   Lin, Yi Ling ^a   Tao, Mi Hua ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c Executive Yuan   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; IMMUNOGLOBULIN G2A; LIVE VACCINE; VIRUS ENVELOPE PROTEIN; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE GUN; GENETIC TRANSFECTION; IMMUNITY; IMMUNIZATION; JAPANESE ENCEPHALITIS VIRUS; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL;

EID: 0032728376     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.12.10137-10145.1999     Document Type: Article

References (46)

1. Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787-793.
2. Boyle, J. S., C. Koniaras, and A. M. Lew. 1997. Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization. Int. Immunol. 9:1897-1906.
3. Boyle, J. S., A. Silva, J. L. Brady, and A. M. Lew. 1997. DNA immunization: induction of higher avidity antibody and effect of route on T cell cytotoxicity. Proc. Natl. Acad. Sci. USA 94:14626-14631.
4. Chambers, T. J., C. S. Hahn, R. Galler, and C. M. Rice. 1990. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 44:649-688.
5. Chen, L. K., C. L. Liao, C. G. Lin, S. C. Lai, C. I. Liu, S. H. Ma, Y. Y. Huang, and Y. L. Lin. 1996. Persistence of Japanese encephalitis virus is associated with abnormal expression of the nonstructural protein NS1 in host cells. Virology 217:220-229.
6. Chow, Y. H., B. L. Chiang, Y. L. Lee, W. K. Chi, W. C. Lin, Y. T. Chen, and M. H. Tao. 1998. Development of Th1 and Th2 populations and the nature of immune responses to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes. J. Immunol. 160:1320-1329.
7. Chow, Y. H., W. L. Huang, W. K. Chi, Y. D. Chu, and M. H. Tao. 1997. Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2. J. Virol. 71:169-178.
8. Devey, M. E., K. Bleasdale, S. Lee, and S. Rath. 1988. Determination of the functional affinity of IgG1 and IgG4 antibodies to tetanus toxoid by isotype-specific solid-phase assays. J. Immunol. Methods 106:119-125.
9. Donnelly, J. J., J. B. Ulmer, J. W. Shiver, and M. A. Liu. 1997. DNA vaccines. Annu. Rev. Immunol. 15:617-648.
10. Feltquate, D. M., S. Heaney, R. G. Webster, and H. L. Robinson. 1997. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J. Immunol. 158:2278-2284.
11. Gregoriadis, G. 1998. Genetic vaccines: strategies for optimization. Pharmaceut. Res. 15:661-670.
12. Haddad, D., S. Liljeqvist, S. Stahl, P. Perlmann, K. Berzins, and N. Ahlborg. 1998. Differential induction of immunoglobulin G subclasses by immunization with DNA vectors containing or lacking a signal sequence. Immunol. Lett. 61:201-204.
13. Hoke, C. H., A. Nisalak, N. Sangawhipa, S. Jatanasen, T. Laorakapongse, B. L. Innis, S. Kotchasenee, J. B. Gingrich, J. Latendresse, K. Fukai, and D. S. Burke. 1988. Protection against Japanese encephalitis by inactivated vaccines. N. Engl. J. Med. 319:608-614.
14. Jan, L. R., C. S. Yang, L. S. Henchal, H. Sumiyoshi, P. L. Summers, D. R. Dubois, and C. J. Lai. 1993. Increased immunogenicity and protective efficacy in outbred and inbred mice by strategic carboxyl-terminal truncation of Japanese encephalitis virus envelope glycoprotein. Am. J. Trop. Med. Hyg. 48:412-423.
15. Juang, R. F., Y. Okuno, T. Fukunaga, M. Tadano, K. Fukai, K. Baba, N. Tsuda, A. Yamada, and H. Yabuuchi. 1983. Neutralizing antibody responses to Japanese encephalitis vaccine in children. Biken J. 26:25-34.
16. Kimura-Kuroda, J., and K. Yasui. 1988. Protection of mice against Japanese encephalitis virus by passive administration with monoclonal antibodies. J. Immunol. 141:3606-3610.
17. Kimura-Kuroda, J., and K. Yasui. 1983. Topographical analysis of antigenic determinants on envelope glycoprotein V3(E) of Japanese encephalitis virus, using monoclonal antibodies. J. Virol. 45:124-132.
18. Konishi, E., and P. W. Mason. 1993. Proper maturation of the Japanese encephalitis virus envelope glycoprotein requires cosynthesis with the pre-membrane protein. J. Virol. 67:1672-1675.
19. Konishi, E., S. Pincus, E. Paoletti, W. W. Laegreid, R. E. Shope, and P. W. Mason. 1992. A highly attenuated host range-restricted vaccinia virus strain, NYVAC, encoding the prM, E, and NS1 genes of Japanese encephalitis virus prevents JEV viremia in swine. Virology 190:454-458.
20. Konishi, E., S. Pincus, E. Paoletti, R. E. Shope, T. Burrage, and P. W. Mason. 1992. Mice immunized with a subviral particle containing the Japanese encephalitis virus prM/M and E proteins are protected from lethal JEV infection. Virology 188:714-720.
21. Konishi, E., K. S. Win, I. Kurane, P. W. Mason, R. E. Shope, and F. A. Ennis. 1997. Particulate vaccine candidate for Japanese encephalitis induces long-lasting virus-specific memory T lymphocytes in mice. Vaccine 15:281-286.
22. Konishi, E., M. Yamaoka, Khin-Sane-Win, I. Kurane, and P. W. Mason. 1998. Induction of protective immunity against Japanese encephalitis in mice by immunization with a plasmid encoding Japanese encephalitis virus premembrane and envelope genes. J. Virol. 72:4925-4930.
23. Kulkarni, A. B., A. Mullbacher, C. R. Parrish, E. G. Westaway, G. Coia, and R. V. Blanden. 1992. Analysis of murine major histocompatibility complex class II-restricted T-cell responses to the flavivirus Kunjin by using vaccinia virus expression. J. Virol. 66:3583-3592.
24. Leitner, W. W., M. C. Seguin, W. R. Ballou, J. P. Seitz, A. M. Schultz, M. J. Sheeny, and J. A. Lyon. 1997. Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites. J. Immunol. 159:6112-6119.
25. Lin, Y. L., L. K. Chen, C. L. Liao, C. T. Yeh, S. H. Ma, J. L. Chen, Y. L. Huang, S. S. Chen, and H. Y. Chiang. 1998. DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice. J. Virol. 72:191-200.
26. Lin, Y. L., C. L. Liao, C. T. Yeh, C. H. Chang, Y. L. Huang, Y. Y. Huang, J. T. Jan, C. Chin, and L. K. Chen. 1996. A highly attenuated strain of Japanese encephalitis virus induces a protective immune response in mice. Virus Res. 44:45-56.
27. Lobigs, M., C. E. Arthur, A. Mullbacher, and R. V. Blanden. 1994. The flavivirus nonstructural protein NS3 is a dominant source of cytotoxic T cell peptide determinants. Virology 202:195-201.
28. Mason, P. W., J. M. Dalrymple, M. K. Gentry, J. M. McCown, C. H. Hoke, D. S. Burke, M. J. Fournier, and T. L. Mason. 1989. Molecular characterization of a neutralizing domain of the Japanese encephalitis virus structural glycoprotein. J. Gen. Virol. 70:2037-2049.
29. Mason, P. W., S. Pincus, M. J. Fournier, T. L. Mason, R. E. Shope, and E. Paoletti. 1991. Japanese encephalitis virus-vaccinia recombinants produce paniculate forms of the structural membrane proteins and induce high levels of protection against lethal JEV infection. Virology 180:294-305.
30. Miura, K., T. Onodera, A. Nishida, N. Goto, and V. Fujisaki. 1990. A single gene controls resistance to Japanese encephalitis virus in mice. Arch. Virol. 112:261-270.
31. Monath, T. P., and F. X. Heinz. 1996. Flaviviruses, p. 961-1034, In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, Pa.
32. Mosmann, T. R., and R. L. Coffman. 1989. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 46:111-147.
33. Pertmer, T. M., M. D. Eisenbraun. D. McCabe, S. K. Prayaga, D. H. Fuller, and J. R Haynes. 1995. Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA. Vaccine 13:1427-1430.
34. Phillpotts, R. J., K. Venugopal, and T. Brooks. 1996. Immunisation with DNA polynucleotides protects mice against lethal challenge with St. Louis encephalitis virus. Arch. Virol. 141:743-749.
35. Porter, K. R., T. J. Kochel, S. J. Wu, K. Raviprakash, I. Phillips, and C. G. Hayes. 1998. Protective efficacy of a dengue 2 DNA vaccine in mice and the effect of CpG immuno-stimulatory motifs on antibody responses. Arch. Virol. 143:997-1003.
36. Schlesinger, J. J., M. Foltzer, and S. Chapman. 1993. The Fc portion of antibody to yellow fever virus NS1 is a determinant of protection against YF encephalitis in mice. Virology 192:132-141.
37. Sin, J. I., J. J. Kim, K. E. Ugen, R. B. Ciccarelli, T. J. Higgins, and D. B. Weiner. 1998. Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes. Eur. J. Immunol. 28:3530-3540.
38. Syrengelas, A. D., T. T. Chen, and R. Levy. 1996. DNA immunization induces protective immunity against B-cell lymphoma. Nat. Med. 2:1038-1041.
39. Takegami, T., H. Miyamoto, H. Nakamura, and K. Yasui. 1982. Biological activities of the structural proteins of Japanese encephalitis virus. Acta Virol. 26:312-320.
40. Tang, D. C., M. DeVit, and S. A. Johnston. 1992. Genetic immunization is a simple method for eliciting an immune response. Nature 356:152-154.
41. Ulmer, J. B., J. J. Donnelly, S. E. Parker, G. H. Rhodes, P. L. Felgner, V. J. Dwarki, S. H. Gromkowski, R. R. Deck, C. M. DeWitt, A. Friedman, L. A. Hawe, K. R. Leander, D. Martinez, H. C. Perry, J. W. Shiver, D. L. Montgomery, and M. A. Liu. 1993. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259:1745-1749.
42. Venugopal, K., and E. A. Gould. 1994. Towards a new generation of flavivirus vaccines. Vaccine 12:966-975.
43. Wengler, G., and G. Wengler. 1989. Cell-associated West Nile flavivirus is covered with E+pre-M protein heterodimers which are destroyed and reor-ganized by proteolytic cleavage during virus release. J. Virol. 63:2521-2526.
44. Wu, S. C., W. C. Lian, L. C. Hsu, and M. Y. Liau. 1997. Japanese encephalitis virus antigenic variants with characteristic differences in neutralization resistance and mouse virulence. Virus Res. 51:173-181.
45. Xiang, Z., and H. C. Ertl. 1995. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 2:129-135.
46. Xin, Y. Y., Z. G. Ming, G. Y. Peng, A. Jian, and L. H. Min. 1988. Safety of a live-attenuated Japanese encephalitis virus vaccine (SA14-14-2) for children. Am. J. Trop. Med. Hyg. 39:214-217.