Cytokines in the muscle tissue of idiopathic inflammatory myopathies: Implications for immunopathogenesis and therapy

European Cytokine Network

Volumn 10, Issue 4, 1999, Pages 471-477

  Megens De Letter, Marie An C J ^a   Visser, Leo H ^b   Van Doorm, Pieter A ^b   Savelkoul, Huub F J ^b  

^a TweeSteden Hospital   (Netherlands)

^b NONE

Author keywords

Cytokines; Immunotherapy; Inflammatory myopathies; Muscle tissue; Regulatory T cell subsets; T cell activation

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN A; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 4; METHOTREXATE; TRANSFORMING GROWTH FACTOR BETA;

BONE MARROW SUPPRESSION; DERMATOMYOSITIS; FEVER; GASTROINTESTINAL SYMPTOM; HEADACHE; HELPER CELL; HUMAN; IDIOPATHIC DISEASE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; INCLUSION BODY MYOSITIS; INFLAMMATION; LIVER TOXICITY; MALAISE; MUSCLE TISSUE; MYALGIA; MYOPATHY; NEPHROTOXICITY; POLYMYOSITIS; REVIEW; STOMATITIS; TERATOGENICITY; THERAPY; VOMITING;

CYTOKINES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; MUSCLE, SKELETAL; MYOSITIS;

ANIMALIA;

EID: 0032710347     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (35)

1. 1. Engel A G, Hohlfeld R, Banker B Q. 1994. The polymyositis and dermatomyositis syndromes. In: Engel A G, Banker B Q, eds. Myology. New York: McGraw-Hill, 1335.
2. 2. Mikol J, Engel A G. 1994. Incusion body myositis. In: Engel A G, Banker B Q. eds. Myology. New York: McGraw-Hill, 1384.
3. 3. Hohlfeld R, Engel A G. 1994. The immunobiology of muscle. (Review) Immunol. Today 15: 269.
4. 4. Dalakas M C. 1998. Molecular immunology and genetics of inflammatory muscle diseases. (Review) Arch. Neurol. 55: 1509.
5. 5. Mosmann T R, Coffman R L. 1989. Th 1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. (Review) Annu. Rev. Immunol. 7: 145.
6. 6. Romagnani S. 1997. The Th1/Th2 paradigm. (Review) Immunol. Today 18: 263.
7. + T cells. J. Immunol. 158: 1085.
8. 8. Romagnani S. 1994. Lymphokine production by human T cells in disease state. (Review) Annu. Rev. Immunol. 12: 227.
9. 9. Robinson D, Shibuya K, Mui A, Zonin F, Murphy E, Sana T, Hartley S B, Menon S, Kastelein R, Bazan F, O' Garra A. 1997. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. Immunity 7: 571.
10. 10. O'Garra A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. (Review) Immunity 8: 275.
11. 11. Baumgarth N, Kelso A. 1996. In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue. J. Virology 70: 4411.
12. 12. Romagnani S. 1998. The Th1/Th2 paradigm and allergic disorders. (Review) Allergy 53 (Suppl 46): 12.
13. 13. Abbas A K, Murphy K M, Sher A. 1996. Functional diversity of helper T lymphocytes. (Review) Nature 363: 787.
14. 14. Takahashi N, Liu M C, Proud D, Yu X Y, Hasegawa S, Spanhake E W. 1994. Soluble intracellular adhesion molecule-1 in bronchioalveolar lavage fluid of allergic subjects following segmental antigen challenge. Am. J. Respir. Crit. Care Med. 150: 704.
15. 15. Tews D S, Goebel H H. 1996. Cytokine expression profile in idiopathic inflammatory myopathies. J. Neuropathol. Exp. Neurol. 55: 342.
16. 16. Lepidi H, Frances V, Figarella-Branger D, Baroli C, Machado-Beata A, Pellissier J F. 1998. Local expression of cytokines in idiopathic inflammatory myopathies. Neuropathol. Appl. Neurobiol. 24: 73.
17. 17. Lundberg I, Ulfgren A K, Nyberg P, Andersson U, Klareskog L. 1997. Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies. Arthritis Rheum. 40: 865.
18. 18. Authier F J, Mhiri C, Chazaud B, Christov C, Cherin P, Barlovatz-Meimon G, Gherardi R K. 1997. Interleukin-1 expression in inflammatory myopathies: evidence of marked immunoreactivity in sarcoid granulomas and muscle fibers showing ischaemic and regenerative changes. Neuropathol. Appl. Neurobiol. 23: 132.
19. 19. Schubert W, Kontozis L, Sticker G, Schwan H, Haraldsen G, Jerusalem F. 1988. Immunofluorescent evidence for presence of interleukin-1 in normal and diseased human skeletal muscle. Muscle Nerve 11: 890.
20. 20. Lindberg C, Oldfors A, Tarkowski A. 1995. Local T cell proliferation and differentiation in inflammatory myopathies. Scand. J. Immunol 41: 421.
21. 21. Emslie-Smith A M, Arahata K, Engel A G. 1989. Major histocompatibility complex class I antigen expression, immunolocalization of interferon subtypes, and T cell mediated cytotoxicity in myopathies. Hum. Pathol. 20: 224.
22. 22. Isenberg D A, Rowe D, Shearer M, Novick D, Beverly P C. 1986. Localization of interferons and interleukin-2 in polymyositis and muscular dystrophy. Clin. Exp. Immunol 63: 450.
23. 23. Lundberg I, Brengman J M, Engel A G. 1995. Analysis of cytokine expression in muscle in inflammatory myopathies, Duchenne dystrophy, and non-weak controls. J. Neuroimmunol. 63: 9.
24. 24. Adams E M, Kirkley J, Eidelman G, Dohlman J, Plotz P H. 1997. The predominance of beta (CC) chemokine transcripts in idiopathic inflammatory muscle diseases. Proc. Assoc. Am. Physicians 109: 275.
25. 25. Thomas M J, Kemeny D M. 1998. Novel CD4 and CD8 T cell subsets. (Review) Allergy 53: 1122.
26. 26. Murphy E, Shibuya K, Hosken N, Openshaw P, Maino V, Davis K, Murphy K, O'garra A. 1996. Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J. E.xp. Med. 183: 901.
27. + T cell subsets in autoimmunity. (Review) Curr. Opin. Immunol. 9: 872.
28. 28. Weiner H L. 1997. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. (Review) Immunol. Today 18: 335.
29. 29. Mastaglia F L, Philips B A, Zilko P. 1997. Treatment of inflammatory myopathies. Muscle Nerve 20: 651.
30. 30. Grau J M, Herrero C, Casademont J, Fernandez-Sola J, Urbano-Marquez A. 1994. Cyclosporin A as first choice for dermatomyositis. J. Rheumatol. 21: 381.
31. 31. Dalakas M C, Illa I, Dambrosia J M, Soueidan S A, Stein D P, Otero C, Dinsmore S T, McCrosky S. 1993. A controlled trial of high-dose intravenous immune globulin infusions as treatment for dermatomyositis. N. Eng. J. Med. 329: 1993.
32. 32. Lundberg I E, Nyberg P. 1998. New developments in the role of cytokines and chemokines in inflammatory myopathies. (Review) Curr. Opin. Rheumatol. 10: 521.
33. 33. Abdul-Ahad A K, Galazka A R, Revel M, Biffoni M, Borden E C. 1997. Incidence of antibodies to interferon-beta in patients treated with recombinant human interferon-beta la from mammalian cells. Cytokines Cell Mol. Ther. 3: 27.
34. 34. Dalakas M C. 1995. Basic aspects of neuroimmunology as they relate to immunotherapeutic targets: present and future prospects. (Review) Ann. Neurol. 37: S2.
35. 35. Engel A G. 1994. Acquired autoimmune myasthenia gravis. In: Engel A G, Banker B Q, eds. Myology. New York: McGraw-Hill: 1769.