메뉴 건너뛰기




Volumn 5, Issue 6, 1999, Pages 351-361

GABA(A) receptors: Diversity and its implications for CNS disease

Author keywords

Anxiolytics; Benzodiazepine receptor; Hypnotics; Ligand gated channel; Aminobutyric acid (GABA)

Indexed keywords

2 PHENYL 5H PYRAZOLO[4,3 C]QUINOLIN 3 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 5 ISOPROPOXY 4 METHYL BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; ALPRAZOLAM; BRETAZENIL; DIAZEPAM; FLUMAZENIL; LORAZEPAM; RECEPTOR SUBUNIT; TEMAZEPAM; ZOLPIDEM;

EID: 0032701285     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849900500610     Document Type: Review
Times cited : (4)

References (49)
  • 1
    • 0002422572 scopus 로고
    • GABA and glycine
    • Bloom FE, Kupfer DJ, editors. New York: Raven Press
    • Paul S. GABA and glycine. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: the fourth generation of progress. New York: Raven Press; 1995. p. 87-94.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 87-94
    • Paul, S.1
  • 2
    • 0028981088 scopus 로고
    • Structure and pharmacology of γ-aminobutyric acid A receptor subtypes
    • Sieghart W. Structure and pharmacology of γ-aminobutyric acid A receptor subtypes. Pharmacol Rev 1995;47:181-234.
    • (1995) Pharmacol Rev , vol.47 , pp. 181-234
    • Sieghart, W.1
  • 3
    • 0030894681 scopus 로고    scopus 로고
    • Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors
    • Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, et al. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature 1997;386:239-46.
    • (1997) Nature , vol.386 , pp. 239-246
    • Kaupmann, K.1    Huggel, K.2    Heid, J.3    Flor, P.J.4    Bischoff, S.5    Mickel, S.J.6
  • 4
    • 0030938936 scopus 로고    scopus 로고
    • G-protein-coupled receptors: Molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
    • Wess J. G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition. FASEB J 1997;11:346-54.
    • (1997) FASEB J , vol.11 , pp. 346-354
    • Wess, J.1
  • 5
    • 0018835633 scopus 로고
    • Receptors for the age of anxiety: Pharmacology of the benzodiazepines
    • Tallman JF, Paul SM, Skolnick P, Gallager DW. Receptors for the age of anxiety: pharmacology of the benzodiazepines. Science 1980;207:274-81.
    • (1980) Science , vol.207 , pp. 274-281
    • Tallman, J.F.1    Paul, S.M.2    Skolnick, P.3    Gallager, D.W.4
  • 7
    • 0021894317 scopus 로고
    • The GABA-ergic system: A locus of benzodiazepine action
    • Tallman JF, Gallager DW. The GABA-ergic system: a locus of benzodiazepine action. Annu Rev Neurosci 1985;8:21-44.
    • (1985) Annu Rev Neurosci , vol.8 , pp. 21-44
    • Tallman, J.F.1    Gallager, D.W.2
  • 8
    • 0023225929 scopus 로고
    • Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor superfamily
    • Schofield PR, Darlison MG, Fujita N, Burt DR, Stephenson FA, Rodriguez H, et al. Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor superfamily. Nature 1987;328:221-7.
    • (1987) Nature , vol.328 , pp. 221-227
    • Schofield, P.R.1    Darlison, M.G.2    Fujita, N.3    Burt, D.R.4    Stephenson, F.A.5    Rodriguez, H.6
  • 10
    • 0028031541 scopus 로고
    • Neurotransmitter-gated ion channels as unconventional allosteric proteins
    • Galzi JL, Changeux JP. Neurotransmitter-gated ion channels as unconventional allosteric proteins. Curr Opin Struct Biol 1994;4: 554-65.
    • (1994) Curr Opin Struct Biol , vol.4 , pp. 554-565
    • Galzi, J.L.1    Changeux, J.P.2
  • 11
    • 0026656037 scopus 로고
    • Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic
    • Galzi JL, DeVillars-Thiery A, Hussy N, Bertrand S, Changeux JP, Bertrand D. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature 1992;359:500-4.
    • (1992) Nature , vol.359 , pp. 500-504
    • Galzi, J.L.1    Devillars-Thiery, A.2    Hussy, N.3    Bertrand, S.4    Changeux, J.P.5    Bertrand, D.6
  • 18
    • 0018099810 scopus 로고
    • GABAergic modulation of benzodiazepine binding site sensitivity
    • Tallman JF, Thomas JW, Gallager DW. GABAergic modulation of benzodiazepine binding site sensitivity. Nature 1978;274:383-5.
    • (1978) Nature , vol.274 , pp. 383-385
    • Tallman, J.F.1    Thomas, J.W.2    Gallager, D.W.3
  • 19
    • 78651189765 scopus 로고
    • On the nature of allosteric transitions: A plausible model
    • Monod J, Changeux JP, Wyman J. On the nature of allosteric transitions: a plausible model. J Mol Biol 1965;12:88-118.
    • (1965) J Mol Biol , vol.12 , pp. 88-118
    • Monod, J.1    Changeux, J.P.2    Wyman, J.3
  • 20
    • 0032215090 scopus 로고    scopus 로고
    • Allosteric receptors after 30 years
    • Changeux JP, Edelstein SJ. Allosteric receptors after 30 years. Neuron 1998;21:959-80.
    • (1998) Neuron , vol.21 , pp. 959-980
    • Changeux, J.P.1    Edelstein, S.J.2
  • 22
    • 0029026443 scopus 로고
    • A receptor gene clusters are derived from an ancestral cluster
    • A receptor gene clusters are derived from an ancestral cluster. Genomics 1995;26:580-6.
    • (1995) Genomics , vol.26 , pp. 580-586
    • McLean, P.J.1    Farb, D.H.2    Russek, S.J.3
  • 23
    • 0028977843 scopus 로고
    • A receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits
    • A receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J Comp Neurol 1995;359:154-94.
    • (1995) J Comp Neurol , vol.359 , pp. 154-194
    • Fritschy, J.M.1    Mohler, H.2
  • 24
    • 0026612363 scopus 로고
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci 1992;12: 1040-63.
    • (1992) J Neurosci , vol.12 , pp. 1040-1063
    • Wisden, W.1    Laurie, H.2    Monyer, H.3    Seeburg, P.H.4
  • 25
    • 0026612362 scopus 로고
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci 1992;12:1063-76.
    • (1992) J Neurosci , vol.12 , pp. 1063-1076
    • Laurie, D.J.1    Wisden, W.2    Seeburg, P.H.3
  • 26
    • 0018628373 scopus 로고
    • Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors
    • Klepner CA, Lippa AS, Benson DI, Sano MC, Beer B. Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors. Pharmacol Biochem Behav 1979;11:457-62.
    • (1979) Pharmacol Biochem Behav , vol.11 , pp. 457-462
    • Klepner, C.A.1    Lippa, A.S.2    Benson, D.I.3    Sano, M.C.4    Beer, B.5
  • 27
    • 0024423323 scopus 로고
    • A-benzodiazepine receptors produced in transfected cells
    • A-benzodiazepine receptors produced in transfected cells. Science 1989;245: 1389-92.
    • (1989) Science , vol.245 , pp. 1389-1392
    • Pritchett, D.B.1    Seeburg, P.H.2
  • 31
    • 0029967726 scopus 로고    scopus 로고
    • Properties of putative cerebellar GABAA receptor isoforms
    • Saxena NC, Macdonald RL. Properties of putative cerebellar GABAA receptor isoforms. Mol Pharmacol 1996;49:567-79.
    • (1996) Mol Pharmacol , vol.49 , pp. 567-579
    • Saxena, N.C.1    Macdonald, R.L.2
  • 34
    • 0030612645 scopus 로고    scopus 로고
    • A receptors underlying inhibitory synaptic currents in neocortical pyramidal neurons
    • A receptors underlying inhibitory synaptic currents in neocortical pyramidal neurons. J Neurosci 1997;17:7220-7.
    • (1997) J Neurosci , vol.17 , pp. 7220-7227
    • Galarreta, M.1    Hestrin, S.2
  • 35
    • 0344942945 scopus 로고    scopus 로고
    • Chromosomes and their disorders
    • Bennet JC, Plum F., editors. Philadelphia: WB Saunders
    • Magenis RE. Chromosomes and their disorders. In: Bennet JC, Plum F., editors. Cecil's textbook of medicine. Philadelphia: WB Saunders; 1996. p. 150-7.
    • (1996) Cecil's Textbook of Medicine , pp. 150-157
    • Magenis, R.E.1
  • 36
    • 0028786947 scopus 로고
    • Deficiency of the β 3 subunit of the type A GABA receptor causes cleft palate in mice
    • Culiat CT, Stubbs L, Woychik J, Russell L, Johnson D, Rinchik E. Deficiency of the β 3 subunit of the type A GABA receptor causes cleft palate in mice. Nat Genet 1995;11:344-6.
    • (1995) Nat Genet , vol.11 , pp. 344-346
    • Culiat, C.T.1    Stubbs, L.2    Woychik, J.3    Russell, L.4    Johnson, D.5    Rinchik, E.6
  • 41
    • 0022647809 scopus 로고
    • Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks
    • Venault P, Chapouthier G, de Carvalho LP, Simiand J, Morre M, Dodd RH, et al. Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks. Nature 1986;321:864-6.
    • (1986) Nature , vol.321 , pp. 864-866
    • Venault, P.1    Chapouthier, G.2    De Carvalho, L.P.3    Simiand, J.4    Morre, M.5    Dodd, R.H.6
  • 42
    • 0013551015 scopus 로고
    • Cognitive enhancing properties of antagonist β-carbolines: New insights into clinical research on the treatment of dementia
    • Maurer K, Riederer P, Beckman H, editors. New York: Springer-Verlag
    • Duka T, Stephens D, Dorow R. Cognitive enhancing properties of antagonist β-carbolines: new insights into clinical research on the treatment of dementia. In: Maurer K, Riederer P, Beckman H, editors. Alzheimer's disease: epidemiology, neuropathology, neurochemistry, and clinics. New York: Springer-Verlag; 1990. p. 555-64.
    • (1990) Alzheimer's Disease: Epidemiology, Neuropathology, Neurochemistry, and Clinics , pp. 555-564
    • Duka, T.1    Stephens, D.2    Dorow, R.3
  • 44
    • 0021240080 scopus 로고
    • Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity
    • Gallager DW, Lakoski JM, Gonsalves SF, Rauch SL. Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity. Nature 1984;308:74-7.
    • (1984) Nature , vol.308 , pp. 74-77
    • Gallager, D.W.1    Lakoski, J.M.2    Gonsalves, S.F.3    Rauch, S.L.4
  • 45
    • 0030111410 scopus 로고    scopus 로고
    • Allosteric uncoupling after chronic benzodiazepine exposure of recombinant GABAA receptors exppressed in Sf9 cells: Efficacy and subtype selectivity
    • Primus RJ, Yu J, Xu J, Hartnett C, Meyyappan M, Kostas C, et al. Allosteric uncoupling after chronic benzodiazepine exposure of recombinant GABAA receptors exppressed in Sf9 cells: efficacy and subtype selectivity. J Pharmacol Exp Ther 1996;276: 882-90.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 882-890
    • Primus, R.J.1    Yu, J.2    Xu, J.3    Hartnett, C.4    Meyyappan, M.5    Kostas, C.6
  • 47
    • 0031957634 scopus 로고    scopus 로고
    • Zolpidem physical dependence assessed across increasing doses under a once-daily dosing regimen in baboons
    • Weerts EM, Ator N, Grech DM, Griffiths RR. Zolpidem physical dependence assessed across increasing doses under a once-daily dosing regimen in baboons. J Pharmacol Exp Ther 1998;285:41-53.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 41-53
    • Weerts, E.M.1    Ator, N.2    Grech, D.M.3    Griffiths, R.R.4
  • 48
    • 0024342317 scopus 로고
    • Relationship of agonist efficacy to changes in GABA sensitivity and anticonvulsant tolerance following chronic benzodiazepine ligand exposure
    • Hernandez TD, Heninger C, Wilson MA, Gallager DW. Relationship of agonist efficacy to changes in GABA sensitivity and anticonvulsant tolerance following chronic benzodiazepine ligand exposure. Eur J Pharmacol 1989;170:145-55.
    • (1989) Eur J Pharmacol , vol.170 , pp. 145-155
    • Hernandez, T.D.1    Heninger, C.2    Wilson, M.A.3    Gallager, D.W.4
  • 49
    • 0029894359 scopus 로고    scopus 로고
    • Ion channels: Too complex for rational drug design
    • Goldstein SAN, Colatsky TJ. Ion channels: too complex for rational drug design. Neuron 1996;16:913-9.
    • (1996) Neuron , vol.16 , pp. 913-919
    • Goldstein, S.A.N.1    Colatsky, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.