Allosteric uncoupling after chronic benzodiazepine exposure of recombinant γ-Aminobutyric AcidA receptors expressed in Sf9 cells: Ligand efficacy and subtype selectivity

Journal of Pharmacology and Experimental Therapeutics

Volumn 276, Issue 3, 1996, Pages 882-890

  Primus, R J ^a   Yu, J ^a   Xu, J ^a   Hartnett, C ^a   Meyyappan, M ^a   Kostas, C ^a   Ramabhadran, T V ^a   Gallager, D W ^a  

^a NEUROGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; HYPNOTIC SEDATIVE AGENT; PYRIDINE DERIVATIVE; ZOLPIDEM;

ALLOSTERISM; ANIMAL; ARTICLE; BINDING COMPETITION; CLASSIFICATION; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; RADIOASSAY; RAT;

ALLOSTERIC REGULATION; ANIMALS; BENZODIAZEPINES; BINDING, COMPETITIVE; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; HYPNOTICS AND SEDATIVES; PYRIDINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA-A;

EID: 0030111410     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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