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Volumn 128, Issue 3, 1999, Pages 823-829

Type I and II metabotropic glutamate receptor agonists and antagonists evoke cardiovascular effects after intrathecal administration in conscious rats

Author keywords

Conscious rat; Intrathecal; Metabotropic glutamate receptors; Spinal cord

Indexed keywords

4 (4,4 DIPHENYLBUTYL)GLUTAMIC ACID; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; METABOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

EID: 0032701124     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702850     Document Type: Article
Times cited : (10)

References (40)
  • 1
    • 0029851966 scopus 로고    scopus 로고
    • Tachycardia after glutamate injection in rat spinal cord is not blocked by kynurenate or mimicked by metabotropic agonists
    • ARNOLDA, L.F., PILOWSKY, P.M., MINSON, J.B., LLEWELLYN-SMITH, I.J. & CHALMERS, J.P. (1996). Tachycardia after glutamate injection in rat spinal cord is not blocked by kynurenate or mimicked by metabotropic agonists. Clin. Exp. Pharm. Physiol., 23, 813-818.
    • (1996) Clin. Exp. Pharm. Physiol. , vol.23 , pp. 813-818
    • Arnolda, L.F.1    Pilowsky, P.M.2    Minson, J.B.3    Llewellyn-Smith, I.J.4    Chalmers, J.P.5
  • 2
    • 0020619444 scopus 로고
    • Effects of GABA and glycine on sympathetic preganglionic neurons in the upper thoracic intermediolateral nucleus of the cat
    • BACKMAN, S.B. & HENRY, J.L. (1983). Effects of GABA and glycine on sympathetic preganglionic neurons in the upper thoracic intermediolateral nucleus of the cat. Brain. Res., 277, 365-369.
    • (1983) Brain. Res. , vol.277 , pp. 365-369
    • Backman, S.B.1    Henry, J.L.2
  • 3
    • 0027417411 scopus 로고
    • Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors
    • BAZIL, M.K. & GORDON, F.J. (1993). Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors. Brain. Res. Bulletin, 31, 273-278.
    • (1993) Brain. Res. Bulletin , vol.31 , pp. 273-278
    • Bazil, M.K.1    Gordon, F.J.2
  • 4
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • CONN, P. & PIN, J.P. (1997). Pharmacology and functions of metabotropic glutamate receptors. Ann. Rev. Pharmacol. Toxicol., 37, 205-237.
    • (1997) Ann. Rev. Pharmacol. Toxicol. , vol.37 , pp. 205-237
    • Conn, P.1    Pin, J.P.2
  • 5
    • 0029998920 scopus 로고    scopus 로고
    • Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat
    • D'AMICO, M., BERRINO, L., PIZZIRUSSO, A., NOVELLIS, V. & ROSSI, F. (1996). Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat. Naunyn-Schmiedeherg's. Arch. Pharmacol., 353, 302-305.
    • (1996) Naunyn-Schmiedeherg's. Arch. Pharmacol. , vol.353 , pp. 302-305
    • D'Amico, M.1    Berrino, L.2    Pizzirusso, A.3    Novellis, V.4    Rossi, F.5
  • 6
    • 0028258843 scopus 로고
    • Functional organization of central pathways regulating the cardiovascular system
    • DAMPNEY, R.A.L. (1994). Functional organization of central pathways regulating the cardiovascular system. Physiol. Rev., 74, 323-364.
    • (1994) Physiol. Rev. , vol.74 , pp. 323-364
    • Dampney, R.A.L.1
  • 7
    • 0029834434 scopus 로고    scopus 로고
    • Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists
    • FISHER, K. & CODERRE, T.J. (1996). Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists. NeuroReport, 7, 2743-2747.
    • (1996) NeuroReport , vol.7 , pp. 2743-2747
    • Fisher, K.1    Coderre, T.J.2
  • 8
    • 0026635029 scopus 로고
    • Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract
    • GLAUM, S.R. & MILLER, R.J. (1992). Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract. J. Neurosci., 12, 2251-2258.
    • (1992) J. Neurosci. , vol.12 , pp. 2251-2258
    • Glaum, S.R.1    Miller, R.J.2
  • 9
    • 0027408298 scopus 로고
    • Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus traclus solitarius of the rat
    • GLAUM, S.R. & MILLER, R.J. (1993). Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus traclus solitarius of the rat. J. Neurosci., 13, 1636-1641.
    • (1993) J. Neurosci. , vol.13 , pp. 1636-1641
    • Glaum, S.R.1    Miller, R.J.2
  • 10
    • 0027759562 scopus 로고
    • The actions of phenylglycine derived metabotropic glutamate receptor antagonists on multiple (1S,3R)-ACPD responses in the rat nucleus of the tractus solitarius
    • GLAUM, S.R., SUNTER, D.C., UDVARHELY, P.M., WATKINS, J.C. & MILLER, R.J. (1993). The actions of phenylglycine derived metabotropic glutamate receptor antagonists on multiple (1S,3R)-ACPD responses in the rat nucleus of the tractus solitarius. Neuropharmacology, 32, 1419-1425.
    • (1993) Neuropharmacology , vol.32 , pp. 1419-1425
    • Glaum, S.R.1    Sunter, D.C.2    Udvarhely, P.M.3    Watkins, J.C.4    Miller, R.J.5
  • 11
    • 0023218063 scopus 로고
    • Role of excitatory amino acids in rat vagal and sympathetic baroreflexes
    • GUYENET, P.G., FILTZ, T.M. & DONALDSON, S.R. (1987). Role of excitatory amino acids in rat vagal and sympathetic baroreflexes. Brain Res., 407, 272-284.
    • (1987) Brain Res. , vol.407 , pp. 272-284
    • Guyenet, P.G.1    Filtz, T.M.2    Donaldson, S.R.3
  • 12
    • 0026602078 scopus 로고
    • Glutamate, NMDA and NMDA receptor antagonists: Cardiovascular effects of intrathecal administration in the rat
    • HONG, Y. & HENRY, J.L. (1992a). Glutamate, NMDA and NMDA receptor antagonists: cardiovascular effects of intrathecal administration in the rat. Brain Res., 569, 38-45.
    • (1992) Brain Res. , vol.569 , pp. 38-45
    • Hong, Y.1    Henry, J.L.2
  • 13
    • 0026657492 scopus 로고
    • Intrathecal administration of non-NMDA receptor agonists increases arterial pressure and heart rate in the rat
    • HONG, Y. & HENRY, J.L. (1992b). Intrathecal administration of non-NMDA receptor agonists increases arterial pressure and heart rate in the rat. Brain Res., 591, 62-68.
    • (1992) Brain Res. , vol.591 , pp. 62-68
    • Hong, Y.1    Henry, J.L.2
  • 14
    • 0026620521 scopus 로고
    • Fast inhibitory postsynaptic potentials and responses to inhibitory amino acids of sympathetic preganglionic neurons in the adult cat
    • INOKUCHI, H., YOSHIMURA, M., TRZEBSKI, A., POLOSA, C. & NISHI, S. (1992). Fast inhibitory postsynaptic potentials and responses to inhibitory amino acids of sympathetic preganglionic neurons in the adult cat. J. Auton. Nerv. Syst., 41, 53-60.
    • (1992) J. Auton. Nerv. Syst. , vol.41 , pp. 53-60
    • Inokuchi, H.1    Yoshimura, M.2    Trzebski, A.3    Polosa, C.4    Nishi, S.5
  • 15
    • 0032836406 scopus 로고    scopus 로고
    • Type I and II metabotropic glutamate receptors (mGluRs) mediate depressor and bradycardic actions in the nucleus of the solitary tract of anaesthetized rats
    • in press
    • JONES, N.M., BEART, P.M., MONN, J.A. & WIDDOP, R.E. (1999). Type I and II metabotropic glutamate receptors (mGluRs) mediate depressor and bradycardic actions in the nucleus of the solitary tract of anaesthetized rats. Eur. J. Pharmacol., in press.
    • (1999) Eur. J. Pharmacol.
    • Jones, N.M.1    Beart, P.M.2    Monn, J.A.3    Widdop, R.E.4
  • 16
    • 0026565232 scopus 로고
    • Ventral medulla stimulation increases blood pressure and spinal cord amino acid release
    • KAPOOR, V., MINSON, J. & CHALMERS, J. (1992). Ventral medulla stimulation increases blood pressure and spinal cord amino acid release. Neuro Report, 3, 55-58.
    • (1992) Neuro Report , vol.3 , pp. 55-58
    • Kapoor, V.1    Minson, J.2    Chalmers, J.3
  • 17
    • 0029926668 scopus 로고    scopus 로고
    • Neurochemical modulation of cardiovascular control in nucleus tractus solitarius
    • LAWRENCE, A.I. & JARROTT, B. (1996). Neurochemical modulation of cardiovascular control in nucleus tractus solitarius. Prog. Neurobiol., 48, 21-53.
    • (1996) Prog. Neurobiol. , vol.48 , pp. 21-53
    • Lawrence, A.I.1    Jarrott, B.2
  • 18
    • 0028792101 scopus 로고
    • Metabotropic and ionotropic glutamate receptors mediate opposite effects on periaqueductal gray matter
    • LEYVA, J., MAIONE, S., PALLOTTA, M., BERRINO, L. & ROSSI, F. (1995). Metabotropic and ionotropic glutamate receptors mediate opposite effects on periaqueductal gray matter. Eur. J. Pharmacol., 285, 125-126.
    • (1995) Eur. J. Pharmacol. , vol.285 , pp. 125-126
    • Leyva, J.1    Maione, S.2    Pallotta, M.3    Berrino, L.4    Rossi, F.5
  • 19
    • 0028864107 scopus 로고
    • Prolonged stimulation of respiration by brain stem metabotropic glutamate receptors
    • LI, A. & NATTIE, E. (1995). Prolonged stimulation of respiration by brain stem metabotropic glutamate receptors. J. Appl. Physiol., 79, 1650-1656.
    • (1995) J. Appl. Physiol. , vol.79 , pp. 1650-1656
    • Li, A.1    Nattie, E.2
  • 20
    • 0026645214 scopus 로고
    • Glulamate-immunoreactive synapses on retrogradely-labelled sympathetic preganglionic neurons in rat thoracic spinal cord
    • LLEWELLYN-SMITH, J.J., PHEND, K.D., MINSON, J.B., PILOWSKY, P.M. & CHALMERS, J.P. (1992). Glulamate-immunoreactive synapses on retrogradely-labelled sympathetic preganglionic neurons in rat thoracic spinal cord. Brain Res., 581, 67-80.
    • (1992) Brain Res. , vol.581 , pp. 67-80
    • Llewellyn-Smith, J.J.1    Phend, K.D.2    Minson, J.B.3    Pilowsky, P.M.4    Chalmers, J.P.5
  • 22
    • 0025997707 scopus 로고
    • Rostal ventrolateral medulla-a source of the glutamatergic innervation of the sympathetic intermediolateral nucleus
    • MORRISON, S.F., CALLAWAY, J., MILNER, T.A. & REIS, D.J. (1991). Rostal ventrolateral medulla-a source of the glutamatergic innervation of the sympathetic intermediolateral nucleus. Brain Res., 562, 126-135.
    • (1991) Brain Res. , vol.562 , pp. 126-135
    • Morrison, S.F.1    Callaway, J.2    Milner, T.A.3    Reis, D.J.4
  • 23
    • 0030029427 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: New target for therapy of neurodegenerative disorders
    • NICOLETTI, F., BRUNO, V., COPANI, A., CASABONA, G. & KNÖPFEL, T. (1996). Metabotropic glutamate receptors: new target for therapy of neurodegenerative disorders. Trends Neurosci., 19, 267-271.
    • (1996) Trends Neurosci. , vol.19 , pp. 267-271
    • Nicoletti, F.1    Bruno, V.2    Copani, A.3    Casabona, G.4    Knöpfel, T.5
  • 24
    • 0031808557 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated excitation and inhibition of sympathetic preganglionic neurones
    • NOLAN, M.F. & LOGAN, S.D. (1998). Metabotropic glutamate receptor-mediated excitation and inhibition of sympathetic preganglionic neurones. Neuropharmacology, 37, 13-24.
    • (1998) Neuropharmacology , vol.37 , pp. 13-24
    • Nolan, M.F.1    Logan, S.D.2
  • 25
    • 0026708456 scopus 로고
    • Evidence for kynurenate-insensitive glutamate receptors in nucleus tractus solitarius
    • PAWLOSKI-DAHM, C. & GORDON, F.J. (1992). Evidence for kynurenate-insensitive glutamate receptors in nucleus tractus solitarius. Am. J. Physiol., 262, H1611-H1615.
    • (1992) Am. J. Physiol. , vol.262
    • Pawloski-Dahm, C.1    Gordon, F.J.2
  • 27
    • 0026523405 scopus 로고
    • Rostrocaudal differences in morphology and neurotransmitter content of cells in the subretrofacial vasomotor nucleus
    • POLSON, J.W., HALLIDAY, G.M., MCALLEN, R.M., COLEMAN, M.J. & DAMPNEY, R.A.L. (1992). Rostrocaudal differences in morphology and neurotransmitter content of cells in the subretrofacial vasomotor nucleus. J. Auton. Nerv. Syst., 38, 117-138.
    • (1992) J. Auton. Nerv. Syst. , vol.38 , pp. 117-138
    • Polson, J.W.1    Halliday, G.M.2    McAllen, R.M.3    Coleman, M.J.4    Dampney, R.A.L.5
  • 28
    • 0019379938 scopus 로고
    • Projections to the spinal cord from neurons close to the ventral surface of the hindbrain in the rat
    • ROSS, C.R., RUGGIERO, D.A. & REIS, D.J. (1981). Projections to the spinal cord from neurons close to the ventral surface of the hindbrain in the rat. Neurosci. Lett., 21, 143-148.
    • (1981) Neurosci. Lett. , vol.21 , pp. 143-148
    • Ross, C.R.1    Ruggiero, D.A.2    Reis, D.J.3
  • 29
    • 0003085990 scopus 로고
    • Pharmacological properties of metabotropic glutamate receptors
    • Conn, P.J. & Patel, J., (eds.). Totowa, NJ: Humana Press Inc.
    • SCHOEPP, D.D. (1994). Pharmacological properties of metabotropic glutamate receptors. In: Conn, P.J. & Patel, J., (eds.). The Metabotropic Glutamate Receptors. Totowa, NJ: Humana Press Inc., pp. 31-58.
    • (1994) The Metabotropic Glutamate Receptors , pp. 31-58
    • Schoepp, D.D.1
  • 30
    • 0028868690 scopus 로고
    • Central neural organization and control of sympathetic nervous system in mammals
    • SUN, M.-K. (1995). Central neural organization and control of sympathetic nervous system in mammals. Prog. Neurobiol., 47, 157-233.
    • (1995) Prog. Neurobiol. , vol.47 , pp. 157-233
    • Sun, M.-K.1
  • 31
    • 0024551523 scopus 로고
    • Cardiac responses to the microinjections of excitatory amino acids into the intermediolateral cell column of the rat spinal cord
    • SUNDARAM, K., MURUGAIAN, J. & SAPRU, H. (1989). Cardiac responses to the microinjections of excitatory amino acids into the intermediolateral cell column of the rat spinal cord. Brain Res., 482, 12-22.
    • (1989) Brain Res. , vol.482 , pp. 12-22
    • Sundaram, K.1    Murugaian, J.2    Sapru, H.3
  • 32
    • 0028030022 scopus 로고
    • Role of metabotropic glutamate receptors in ventrolateral medulla of hypertensive rats
    • TSUCHIHASHI, T., ABE, I. & FUJISHIMA, M. (1994). Role of metabotropic glutamate receptors in ventrolateral medulla of hypertensive rats. Hypertension, 24, 648-652.
    • (1994) Hypertension , vol.24 , pp. 648-652
    • Tsuchihashi, T.1    Abe, I.2    Fujishima, M.3
  • 33
    • 0027456582 scopus 로고
    • Metabotropic glutamate receptors in the ventrolateral medulla of rats
    • TSUCHIHASHI, T. & AVERILL, D.B. (1993). Metabotropic glutamate receptors in the ventrolateral medulla of rats. Hypertension, 21, 739-744.
    • (1993) Hypertension , vol.21 , pp. 739-744
    • Tsuchihashi, T.1    Averill, D.B.2
  • 34
    • 0031049749 scopus 로고    scopus 로고
    • Pressor and sympathetic responses to excitatory amino acids are not augmented in the ventrolateral medulla of Dahl salt-sensitive rats
    • TSUCHIHASHI, T., KAGIYAMA, S., ONAKA, U., ABE, I. & FUJISHIMA, M. (1997). Pressor and sympathetic responses to excitatory amino acids are not augmented in the ventrolateral medulla of Dahl salt-sensitive rats. Brain Res., 750, 195-200.
    • (1997) Brain Res. , vol.750 , pp. 195-200
    • Tsuchihashi, T.1    Kagiyama, S.2    Onaka, U.3    Abe, I.4    Fujishima, M.5
  • 35
    • 0027180311 scopus 로고
    • Excitatory amino acid receptors in the nucleus tractus solitarius mediate responses to the stimulation of cardio-pulmonary vagal afferent C fiber endings
    • VARDHAN, A., KACHROO, A. & SAPRU, H.N. (1993a). Excitatory amino acid receptors in the nucleus tractus solitarius mediate responses to the stimulation of cardio-pulmonary vagal afferent C fiber endings. Brain Res., 618, 23-31.
    • (1993) Brain Res. , vol.618 , pp. 23-31
    • Vardhan, A.1    Kachroo, A.2    Sapru, H.N.3
  • 36
    • 0027530395 scopus 로고
    • Excitatory amino acid receptors in commissural nucleus of the NTS mediate carotid chemoreceptor responses
    • VARDHAN, A., KACHROO, A. & SAPRU, H.N. (1993b). Excitatory amino acid receptors in commissural nucleus of the NTS mediate carotid chemoreceptor responses. Am. J. Physiol., 33, R41-R50.
    • (1993) Am. J. Physiol. , vol.33
    • Vardhan, A.1    Kachroo, A.2    Sapru, H.N.3
  • 37
    • 0025324722 scopus 로고
    • Intrathecal kynurenate reduces arterial pressure, heart rate and baroreceplor-heart rate reflex in conscious rats
    • VERBERNE, A.J.M., WIDDOP, R.E., MACCARRONE, C., JARROTT, B., BEART, P.M. & LOUIS, W.J. (1990). Intrathecal kynurenate reduces arterial pressure, heart rate and baroreceplor-heart rate reflex in conscious rats. Neurosci. Lett., 114, 309-315.
    • (1990) Neurosci. Lett. , vol.114 , pp. 309-315
    • Verberne, A.J.M.1    Widdop, R.E.2    MacCarrone, C.3    Jarrott, B.4    Beart, P.M.5    Louis, W.J.6
  • 38
    • 0028334456 scopus 로고
    • Metabotropic glutamate receptors are involved in the control of breathing at the medulla oblongata level of anaesthetized rats
    • VITAGLIANO, S., BERRINO, L, PIZZIRUSSO, A., D'AMICO, M., CALDERARO, V., MAIONE, S. & ROSSI, F. (1994). Metabotropic glutamate receptors are involved in the control of breathing at the medulla oblongata level of anaesthetized rats. Neuropharmacology, 33, 859-864.
    • (1994) Neuropharmacology , vol.33 , pp. 859-864
    • Vitagliano, S.1    Berrino, L.2    Pizzirusso, A.3    D'Amico, M.4    Calderaro, V.5    Maione, S.6    Rossi, F.7
  • 39
    • 0030026587 scopus 로고    scopus 로고
    • (2S, 4S)-2-amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid: A potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase
    • WERMUTH, C.G., MANN, A., SCHOENFELDER, A., WRIGHT, R.A., JOHNSON, B.G., BURNETT, J.P., MAYNE, N.G. & SCHOEPP, D.D. (1996). (2S, 4S)-2-amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid: a potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase. J. Med. Chem., 39, 814-816.
    • (1996) J. Med. Chem. , vol.39 , pp. 814-816
    • Wermuth, C.G.1    Mann, A.2    Schoenfelder, A.3    Wright, R.A.4    Johnson, B.G.5    Burnett, J.P.6    Mayne, N.G.7    Schoepp, D.D.8
  • 40
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • YAKSH, T.L. & RUDY, T.A. (1976). Chronic catheterization of the spinal subarachnoid space. Physiol. Behavior, 17, 1031-1036.
    • (1976) Physiol. Behavior , vol.17 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.A.2


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