Retreat from Nuremberg: Can we prevent unethical medical research?

Public Health

Volumn 113, Issue 5, 1999, Pages 205-210

  Horner, J Stuart ^a  

^a Beth Shemesh   (United Kingdom)

Author keywords

Consent; Ethics; Human rights; Research; Vulnerable groups

Indexed keywords

COMPETENCE; DEVELOPING COUNTRY; GOVERNMENT; HUMAN RIGHTS; INFORMED CONSENT; MEDICAL ETHICS; MEDICAL RESEARCH; PRISONER; REVIEW; UNITED KINGDOM;

EID: 0032700054     PISSN: 00333506     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0033-3506(99)00160-2     Document Type: Review

References (50)

1. Mozes-Kor E. The Mengele Twins and Human Experimentation: A Personal Account. In: Nazi doctors and the Nuremberg Code. Annas GJ and Grodin MA (eds). Oxford University Press: New York and Oxford, 1992. p 58.
2. Nuremberg Code. Br Med J 1996; 313: 1448.
3. Seidelman WE. Nuremberg lamentation: for the forgotten victims of medical science. Br Med J 1996; 313: 1463-1473.
4. Shuster E. The Nuremberg Code: Hippocratic ethics and human rights. Lancet 1998; 351: 974-977.
5. Declaration of Helsinki. Br Med J 1996; 313: 1448.
6. Harkness JM. Nuremberg and the issue of wartime experiments on US prisoners. JAMA 1996; 276: 1672-1657.
7. Vollmann J, Winau R. Informed consent in human experimentation before the Nurembere code. Br Med J 1996; 313: 1445-1447.
8. Hornblum AM. They were cheap and available: prisoners as research subjects in twentieth century America. Br Med J 1997; 315: 1437-1441.
9. Weindling P. Human guinea pigs and the ethics of experimentation: the BMJ's corespondent at the Nuremberg medical trial. Br Med J 1996; 313: 1467-1470.
10. Angell M. The Nazi hypothermia experiments and unethical research today (editorial). N Eng J Med 1990; 322: 1462-1464.
11. Berger R. Nazi Science - The Dachau hypothermia experiments. N Eng J Med 1990; 322: 1435-1440.
12. Harris SH. Factories of Death. Routledge: London, England, 1994. a) p 202;
13. b) p 221;
14. c) p 222.
15. Annas GJ. The Nuremberg Code in U.S. Courts: Ethics versus expediency in Nazi doctors and the Nuremberg Code. Annas GJ, Grodin MA(eds). Oxford University Press: New York and Oxford, 1992, pp. 201-222.
16. Katz J. The Nuremberg Code and the Nuremberg Trial. JAMA 1996; 276: 1662-1666.
17. Fox RC. Experiment perilous: Physicians and Patients Facing the Unknown. University of Pennsylvania Press: Philadelphia, 1974.
18. Faden FR, Lederer SE, Moreno JD. US Medical Researchers, the Nuremberg Doctors Trial, and the Nuremberg Code. JAMA 1996; 276; 1667-1671.
19. US Department of Health, Education and Welfare. Final Report of the Tuskegee, Syphilis Study. Ad Hoc Advisory Panel, Washington DC, 1973.
20. Kenyon G. Australian army infected troops and internees in second world war. Br Med J 1999; 318: 1233.
21. Cassileth BR, Vlassov VV, Chapman CC. Health Care, Medical Practice and Medical Ethics in Russia today. JAMA 1995; 273: 1569-1573.
22. Beecher HK. Ethics and clinical research. N Eng J Med 1966; 274; 1354-1360.
23. Pappworth MH. Human Guinea Pigs - experimentation on man. Routledge and Kegan Paul: London, 1967.
24. Pappworth MH. 'Human guinea pigs' A history. Br Med J 1990; 301: 1456-1460.
25. Lock S. Monitoring research ethical committees. The profession must establish effective mechanisms. Br Med J 1990; 301: 61-62.
26. Doyal L. Journals should not publish research to which patients have not given fully informed consent - with three exceptions. Br Med J 1997; 314: 1107-1111.
27. Neuberger J. Ethics and Health Care. The role of ethics committees in the United Kingdom. King's Fund Institute: London, 1992.
28. Savulesco J, Chalmers I, Blunt J. Are research ethics committees behaving unethically? Br Med J 1996; 313: 1390.
29. Smith T, Moore EJH, Tunstall-Pedoe H. Review by a local medical research ethics committee of the conduct of approved research projects. Br Med J 1997; 314: 1588-1589.
30. Parkins KJ, Poets CF, OBrien LM, Stebbens VA, Southall DP. Effect of exposure to 15% oxygen on breathing patterns and oxygen saturation in infants: interventional study. Br Med J 1998; 316: 887-894.
31. Hick C. Codes and morals: Is there a missing link (The Nuremberg Code revisited). Medicine, Health Care and Philosophy 1998; 1: 143-154.
32. Grady C. Science in the service of healing. Hastings Center Report 28, 1998, pp 34-38.
33. Skrabanek P, McCormick J. Follies and Fancies in Medicine. The Tarragon Press: Glasgow, 1989, p 169.
34. Angell M. Editorial Responsibility: Protecting Human Rights by Restricting Publication of Unethical Research in Nazi doctors and the Nuremberg Code. Annas GJ and Grodin MA (eds). Oxford University Press: New York and Oxford, 1992, pp 276-285.
35. Glantz LH. The Influence of the Nuremberg Code on U.S. Statutes and Regulations in Nazi doctors and the Nuremberg Code. Annas GJ and Grodin MA, (eds). Oxford University Press: New York and Oxford, 1992, 371.
36. Alderson P. In the genes or in the stars? Children's competence to consent. J Med Ethics 1992; 18: 119-124.
37. Nicholson RH. Medical Research with children: ethics, law and practice. Oxford University Press: Oxford, 1986.
38. Pearce J. Consent to treatment during childhood. Br J Psych 1994; 165: 713-716.
39. Gillon R. Medical Ethics and the Goals of Medicine: Inaugural Professorial Lecture, Imperial College, University of London. 18th February 1997.
40. Agich GJ. Autonomy and Long Term Care. Oxford University Press: New York, 1993, p 197.
41. British Medical Association and the Royal College of Nursing. The Older Person: Consent and Care. British Medical Association: London, 1995.
42. Olde Rikkert MGM; ten Have HAMJ, Hoefnagels WHL. Informed consent in biomedical studies on aging; survey of four journals. Br Med J 1996; 313: 117.
43. Kellett JM. A nurse is suspended. Br Med J 1996; 313: 1249.
44. Wendler D. When should 'riskier' subjects be excluded from research participation? Kennedy Inst Ethics J 1998; 8: 307-327.
45. Gambia Government/Medical Research Council Joint Ethical Committee. Ethical issues facing medical research in developing countries. Lancet 1998; 351: 286-287.
46. Glantz LH, Annas GJ, Grodin MA, Mariner WK. Research in developing countries: Taking 'benefit' seriously. Hastings Center Report, 28 1998; 38-42.
47. Law Commission 1993. Consultation Paper 129. Mentally Incapacitated Adults and Decision Making: Medical Treatment and Research. HMSO: London, 1993.
48. Lord Chancellor's Department. Who Decides? Making decisions on Behalf of Mentally Incapacitated Adults A Consultation Paper Cm 3808. HMSO: London, 1997.
49. McNeill PM. The Ethics and Politics of Human Experimentation. Cambridge University Press. 1993, (N.B. see pp 247 and 315).
50. Pearn J. Publication: an ethical imperative. Br Med J 1995; 310: 313.