Expression of P27(kip1) and ki-67 in pituitary adenomas: An investigation of marker of adenoma invasiveness

Acta Neurochirurgica

Volumn 141, Issue 2, 1999, Pages 187-192

  Zhao, D ^a   Tomono, Y ^a   Nose, T ^a   Luedecke, D ^b   Buchfelder, M ^b   Fahlbusch, R ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NONE

Author keywords

Immunohistochemically; Invasiveness; Ki 67; p27(Kip1)

Indexed keywords

KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67; PROTEIN P27; TUMOR MARKER; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ENZYME INHIBITOR; MICROTUBULE ASSOCIATED PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADOLESCENT; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER INVASION; CELL LABELING; CLINICAL TRIAL; FEMALE; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; HYPOPHYSIS; HYPOPHYSIS TUMOR; MIDDLE AGED; PATHOLOGY; PROGNOSIS;

ADOLESCENT; ADULT; AGED; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENZYME INHIBITORS; FEMALE; HUMANS; KI-67 ANTIGEN; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM INVASIVENESS; PITUITARY GLAND; PITUITARY NEOPLASMS; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 0032610766     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007010050285     Document Type: Article

References (29)

1. Buchfelder M, Fahlbusch R, Adams EF, Kiesewetter F, Thierauf P (1996) Proliferation parameters for pituitary adenomas. Acta Neurochir [Suppl] (Wien) 65: 18-21
2. Cattoretti G, Becker MHG, Key G, Duchrow M, Schluter C, Galle J, Gerdes J (1992) Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB-1 and MIB-3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 168: 357-363
3. Catzavelos C, Bhattacharya N, Ung YC, Wilson J, Roncari L, Sandhu C, Shaw P, Yeger H, Morava-Protzner I, Kapusta L, Franssen E, Pritchard KI, Slingerland JM: Decreased levels of the cell-cycle inhibitor p27 protein (1997) Prognostic implication in primary breast cancer. Nature Med 3: 227-230
4. kip1. J Clin Inves 97: 1983-1988
5. Daita G, Yonemasu Y (1996) Dural invasion and proliferrative potential of pituitary adenomas. Neurol Med Chir (Tokyo) 36: 211-214
6. kip1deficient mice. Cell 85: 733-744
7. Gerdes J (1990) Ki-67 and other proliferation markers useful for immuno-histological diagnostic evaluation in human malignancies. Seminars in Cancer Biology 1: 199-206
8. Hardy J (1969) Transphenoidal microsurgery of the normal and pathological pituitary. Clin Neurosurg 16: 185-217
9. Hsu SM, Raine L, Fanger H (1981) The use of antiavidin antibody and avidin-biotin peroxidase complex in immunoperoxidase technics. Am J Clin Pathol 75: 816-821
10. Kitz K, Knosp E, Koos WTH, Korn A (1991) Proliferation in pituitary adenomas. Measurement by MAB Ki 67. Acta Neurochir [Suppl] (Wien) 53: 60-64
11. kip1. Cell 85: 721-732
12. Knosp E, Kitz K, Perneczky A (1989) Proliferation activity in pituitary adenomas: Measurement by monoclonal antibody Ki-67. Neurosurgery 25: 927-930
13. Knosp E, Steiner E, Kitz K, Matula CM (1993) Pituitary adenomas with invasion of the cavernous sinus space: A magnetic resonance imaging classification compared with surgical findings. Neurosurgery 33: 610-617
14. Kovacs K, Horvath E (1986) Tumors of the pituitary gland. In: Atlas of Tumor Pathology. Toronto, Ontario. pp I-269
15. Landolt A, Shibata T, Kleihues P (1987) Growth rate of human pituitary adenomas. J Neurosurg 67: 803-806
16. kip1 expression in endocrine and other tumors. Ame J Pathol 150: 401-407
17. Martins AN, Hayes GJ, Kempe LG (1965) Invasive pituitary adenomas. J Neurosurg 22: 268-276
18. Melmed S, Fagin J, Leung M (1986) Bromocriptine inhibits incorperation of [3H] thymidine into rat pituitary tumor cells. Brain Res 369: 83-90
19. kip1 display increased body size, multiple organ hyperplasia, retina dysplasia, and pituitary tumors. Cell 85: 707-720
20. Pines J (1993) Cyclins and cyclin-dependent kinases; take your partners. Trends Biochem Sci 18: 195-197
21. kip1, a cyclin-Cdk inhibitor, links transforming growth factors-β and contact inhibitor to cell cycle arrest. Genes Dev 8: 9-22
22. kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66
23. Qian X, Jin L, Grande JP, Lloyd RV (1996) Transforming growth factor-β and p27 expression in pituitary cells. Endocrinology 137: 3051-3060
24. Reed SI (1992) The role of p34 kinase in the G1 to S-phase transition. Annu Rev Cell Biol 8: 529-561
25. Scheithauer BW, Kovacs KT, Laws ER Jr, Randall RV (1986) Pathology of invasive pituitary tumors with special reference to functional classification. J Neurosurg 65: 733-744
26. Selman WR, Laws ER Jr, Scheithauer BW, Carpenter SM (1986) The occurrence of dura invasion in pituitary adenomas. J Neurosurg 64: 402-407
27. Tan P, Cady B, Wanner M, Cukor B, Magi-Galluzzi C, Lavin P, Draetta G, Pagano M, Loda M (1997) The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a, b) invasive breast carcinomas. Cancer Res 57: 1259-1263
28. Thapar K, Kovacs K, Scheithauer BW, Stefaneanu L, Horvath E, Pernicone PJ, Murray D, Laws ER (1996) Proliferative activity and invasiveness among pituitary adenomas and carcinomas: An analysis using the MIB-1 antibody. Neurosurgery 38: 99-107
29. Toyoshima H, Hunter T (1994) p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74