Glucocorticoid induced apoptosis in leukemia

Advances in Experimental Medicine and Biology

Volumn 457, Issue , 1999, Pages 607-614

  Smets, Lou A ^a   Salomons, Gajja ^a   Van Den Berg, Joop ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Apoptosis; Bcl 2; Glucocorticoids; Leukemia; Mitochondria; Resistance

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; ONCOPROTEIN; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; CELL DIVISION; DRUG EFFECT; GENETICS; HUMAN; LEUKEMIA; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROGNOSIS; REVIEW;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL DIVISION; GLUCOCORTICOIDS; HUMANS; LEUKEMIA; PROGNOSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, GLUCOCORTICOID;

EID: 0032605943     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4811-9_67     Document Type: Article

References (29)

1. Gregory, C., and Milner, A. Regulation of cell survival in Burkitt lymphoma: implications from studies of apoptosis following cold-shock treatment. Int. J. Cancer 1994, 57, 419-426.
2. Smets, L. Programmed cell death (apoptosis) and response to anti-cancer drugs. Anti-Cancer Drugs 1994, 5, 3-9.
3. Schinkel, A. The physiological function of drug-transporting P-glycoproteins. Seminars in Cancer Biology 1997, 8, 161-170.
4. Kaspers, G., Pieters, R., Klumper, E., De Waal, F., and Veerman, A. Glucocorticoid resistance in childhood leukemia. Leukemia and Lymphoma 1994, 13, 187-201.
5. wt mouse lymphoma cells incubated with dexamethasone. J. Steroid Biochem. Molec. Biol. 1994, 51, 33-40.
6. Van den Berg, J., Smets, L., Van den Elshout, M, Van Geel, I., and Janssen, M. Temperature dependence of glucocorticoid binding in sensitive and refractory murine leukaemia cells. Leuk. Res. 1993, 17, 263-269.
7. Dowd, D. and Miesfeld, R. Evidence that glucocorticoid- and cyclic AMP-induced apoptotic pathways share distal events. Mol. Cell Biol. 1992, 12, 3600-3608.
8. Smets, L., Salomons, G., Van Rooij, H., and Van den Berg, J. Involvement of the glucocorticoid receptor in stress-induced apoptosis of leukemic cells. Leukemia 1998, 12, 406-413.
9. 1 arrest and death of a human lymphoid cell line. J. Cell. Physiol. 1979, 98, 267-278.
10. Smets, L., Bout, B., Brouwer, M., and Tulp, A. Cytotoxic effects of dexamethasone restricted to non-cycling, early G1-phase cells of L1210 leukemia. J. Cell Physiol. 1983, 116, 397-403.
11. Smets, L. and Van den Berg, J. Bcl-2 expression and glucocorticoid-induced apoptosis of leukemic and lymphoma cells. Leukemia and Lymphoma 1996, 20, 199-205.
12. Hardin, J. McLeod, S., Grigoriva, A., Chang, R., Barlogie, B., Xiao, H. and Epstein, J. Interleukin-6 prevents dexamethasone-induced myeloma cell death. Blood 1994, 84, 3063-3070.
13. Sachs, L., and Lotem, J. Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood 1993, 82, 15-21.
14. Smets, L., Slater, R., Van Wering, E., Van der Does-van den Berg, A., Hart, A., Veerman, A., and Kamps, W. DNA index and %S-phase cells determined in acute lymphoblastic leukemia of children: a report from studies ALL V, ALL VI and ALL VIII (1979-1991) of the Dutch Childhood Leukemia Study Group and The Netherlands Workgroup on Cancer Genetics and Cytogenetics. Med. Pediatr. Oncol. 1995, 25. 437-444.
15. Clarke, A., Purdie, C., Harrison, D., Morris, R., Bird, C., Hooper, M., and Wyllie, A. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993, 362, 894-852.
16. Smets, L., van den Berg, J., Acton, D., Top, B., Van Rooij, H., and Verwijs-Janssen, M. BCL-2 expression and mitochondrial activity in leukemic cells with different sensitivity to glucocorticoid-induced apoptosis. Blood 1994, 84,1613-1619.
17. Reed, J. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 1994, 124, 1-6.
18. Salomons, G., Brady, H., Verwijs-Janssen, M, Van den Berg, J., Hart, A., Van den Berg, H., Behrendt, H., Hählen, K., and Smets, L. The Baxα:Bcl-2 ratio modulates the response to dexamethasone in leukemic cells and is highly variable in childhood acute leukemia. Int. J. Cancer 1997, 71, 959-965.
19. Salomons, G., Buitenhuis, C., Martinez Muñoz,C., Verwijs-Janssen, M., Behrendt, H., Zsiros, J., and Smets, L. Mutational analysis of bax and bcl-2 in childhood acute lymphoblastic leukemia. Int. J. Cancer 1998 179, 273-277.
20. Brady, H., Salomons, G., Bobeldijk, R. and Berns, A. T cells from baxα transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA-damage-induced cell death in the absence of p53. EMBO J. 1996, 15, 1221-1230.
21. Uckun, F., Yang, Z., Sather, H., Steinherz, P., Nachman, J., Bostrom, B., Crotty, L., Sarquis, M., Ek, O., Zeren, T., Tubergen, D., Reaman, G., and Gaynon, P. Cellular expression of antiapoptotic Bcl-2 oncoprotein in newly diagnosed childhood acute lymphoblastic leukemia: a children's cancer group study. Blood 1997, 89, 2506-2509.
22. Coustan-Smith, E., Kitanaka, A, Pui, C., McNinch, L., Evans, W., Raimondi, S., Behm, F., Arico, M., and Campana, D. Clinical relevance of Bcl-2 over-expression in childhood acute lymphoblastic leukemia. Blood 1996, 87, 1140-1146.
23. Pietenpol, J., Papadopoulos, N, Markowitz, S., Willson, J., Kinzler, K., and Vogelstein, B. Paradoxical inhibition of solid-tumor cell growth by bcl2. Cancer Res. 1994, 54, 3714-3717.
24. Brady, H., Gil-Gomez, G., Kirberg, J., and Berns, A. Baxα perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 1996, 15, 6991-7001.
25. Huang, D., O'Reilly, A., Strasser, A., and Cory, S. The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J. 1997, 16, 4628-4638.
26. Decaudin, D., Geley, S., Hirsch, T., Castedo, M., Marchetti, P., Macho, A., Kofler, R., and Kroemer, G. Bcl-2 and Bel-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res. 1997, 57, 62-67.
27. Van den Berg, J., Smets, L., and Van Rooij, H. Agonist-free transformation of the glucocorticoid receptor in human B-lymphoma cells. J. Steroid Biochem. Mol. Biol. 1996, 57, 239-249.
28. Klumper, E. Thesis 1995, Free University, Amsterdam.
29. Kaspers, G., Veerman, A., Pieters, R., Van Zantwijk, C. Smets, L., Van Wering, E., and Van der Does-Van den Berg, A. In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia. Blood 1997, 90, 2723-2729.