Regulation by glycine, Mg2+ and polyamines of the N-methyl-D-aspartate-induced locomotion in the neonatal rat spinal cord in vitro

Neuroscience

Volumn 94, Issue 4, 1999, Pages 1199-1206

  Bertrand, S ^a   Cazalets, J R ^a  

^a CNRS Laboratoire de Neurobiologie et Mouvements   (France)

Author keywords

7 Chlorokynurenic acid; Arcaine; Spermine

Indexed keywords

ARCAINE; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLYAMINE; SPERMINE; 7 CHLOROKYNURENIC ACID; 7-CHLOROKYNURENIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; BIGUANIDE DERIVATIVE; DRUG DERIVATIVE; GLYCINE; KYNURENIC ACID; MAGNESIUM; N METHYLASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LOCOMOTION; MOTONEURON; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; MOTOR ACTIVITY; PHYSIOLOGY; SYNAPSE; WISTAR RAT;

ANIMALS; BIGUANIDES; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; KYNURENIC ACID; MAGNESIUM; MOTOR ACTIVITY; MOTOR NEURONS; N-METHYLASPARTATE; POLYAMINES; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE; SPINAL CORD; SYNAPSES;

EID: 0032585911     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00301-2     Document Type: Article

References (42)

1. Benveniste M., Mayer M.L. Multiple effects of spermine on N-methyl-D-aspartate acid responses of rat cultured hippocampal neurones. J. Physiol., Lond. 464:1993;131-163.
2. Bertrand S., Cazalets J.-R. Postinhibitory rebound during locomotor-like activity in neonatal rat motoneurons in vitro. J. Neurophysiol. 79:1998;342-351.
3. Bracci E., Ballerini L., Nistri A. Spontaneous rhythmic bursts induced by pharmacological block of inhibition in lumbar motoneurons of the neonatal rat spinal cord. J. Neurophysiol. 75:1996;640-646.
4. Brodin L., Grillner S. Effects of magnesium on fictive locomotion induced by activation of N-methyl-D-aspartate (NMDA) receptors in the lamprey spinal cord in vitro. Brain Res. 380:1986;244-252.
5. Cazalets J.R., Borde M., Clarac F. Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat. J. Neurosci. 15:1995;4943-4951.
6. Cazalets J.R., Borde M., Clarac F. The synaptic drive from the spinal locomotor network to motoneurons in the newborn rat. J. Neurosci. 15:1996;298-306.
7. Cazalets J.R., Sqalli-Houssaini Y., Clarac F. Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat. J. Physiol., Lond. 455:1992;187-204.
8. Cohen A.H., Harris-Warrick R.M. Strychnine eliminates alternating motor output during fictive locomotion in the lamprey. Brain Res. 293:1984;164-167.
9. Cowley K.C., Schmidt B.J. Regional distribution of the locomotor pattern-generating network in the neonatal rat spinal cord. J. Neurophysiol. 77:(1):1997;247-259.
10. Cowley K.C., Schmidt B.J. Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. J. Neurophysiol. 74:1995;1109-1117.
11. Dale N. Reciprocal inhibitory interneurones in the Xenopus embryo spinal cord. J. Physiol. 363:1995;61-70.
12. Gaiarsa J. L., Corradetti R., Cherubini E. and Ben-Ari Y. (1990) The allosteric glycine site of the N-methyl-D-aspartate receptor modulates GABAergic-mediated synaptic events in neonatal rat CA3 hippocampal neurons., Proc. natn. Acad. Sci. 87, 343-346.
13. Grillner P., Hill R., Grillner S. 7-Chlorokynurenic acid blocks the NMDA receptor-induced locomotion in lamprey - evidence for a physiological role of the glycine site. Acta physiol. scand. 141:1991;131-132.
14. Grillner S., Matsushima T. The neural network underlying locomotion in lamprey - synaptic and cellular mechanisms. Neuron. 7:1991;1-15.
15. Hussy N., Boissin-Agasse L., Richard P., Desarmenien M.G. NMDA receptor properties in rat supraoptic magnocellular neurons: characterization and postnatal development. Eur. J. Neurosci. 9:1997;1439-1449.
16. 2+ of N-methyl-D-aspartate-activated channels. Biophy. J. 57:1990;1085-1090.
17. Johnson J.W., Ascher P. Glycine potentiates the NMDA response in culture mouse brain neurones. Nature. 325:1987;529-531.
18. Kalb R.G., Lidow M.S., Halsted M.J., Hockfield S. N-methyl-D-aspartate receptors are transiently expressed in the developing spinal cord ventral horn. Proc. natn. Acad. Sci. U.S.A. 89:1992;8502-8506.
19. Kemp J.A., Foster A.C., Leeson P.D., Priestley T., Tridgett R., Iversen L.L., Woodruff G.N. 7-chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc. natn. Acad. Sci. U.S.A. 85:1988;6547.
20. Kiehn O., Kjaerulff O. Spatiotemporal characteristics of 5HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat. J. Neurophysiol. 75:1996;1472-1482.
21. Kjaerulff O., Kiehn O. Crossed rhythmic synaptic input to motoneurons during selective activation of the contralateral spinal locomotor network. J. Neurosci. 17:1997;9433-9447.
22. Kjaerulff O., Kiehn O. Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study. J. Neurosci. 16:1996;5777-5794.
23. Kloog Y., Lamdani-Itkin H., Sokolovsky M. The glycine site of the N-methyl-D-aspartate receptor channel: differences between binding of HA-966 and of 7-chlorokynurenic acid. J. Neurochem. 54:1990;1576.
24. Kremer E., Lev-Tov A. Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J. Neurophysiol. 77:1997;1155-1170.
25. Kudo N., Ozaki S. and Yamada T. (1991) Ontogeny of rhythmic activity in the spinal cord of the rat. In Neurobiological Basis of Human Locomotion, (eds Shimamura M., Grillner S. and Edgerton V. R.), pp. 127-136. Japan Scientific Societies Press, Tokyo.
26. Kudo N., Yamada T. N-Methyl-D,L-aspartate induced locomotor activity in a spinal cord-hindlimb muscles preparation of the newborn rat studied in vitro. Neurosci. Lett. 75:1987;43-48.
27. Maruoka Y., Ohno Y., Tanaka H., Yasuda H., Ohtani K., Sakamoto H., Kawabe A., Tamamura C., Nakamura M. Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro. Gen. Pharmac. 29:1997;645-649.
28. Marvizon J.-C., Baudry M. NMDA receptor activation by spermine requires glutamate but not glycine. Eur. J. Pharmac. molec. Pharmac. 244:1993;103-104.
29. 2+ of NMDA response in spinal cord neurones. Nature. 309:1984;263-361.
30. Pinco M., Lev-Tov A. Synaptic excitation of α-motoneurons by dorsal root afferents in the neonatal rat spinal cord. J. Neurophysiol. 70:1993;406-417.
31. Pratt C.A., Jordan L.M. Ia inhibitory interneurons and Renshaw cells as contributors to the spinal mechanisms of fictive locomotion. J. Neurophysiol. 57:1987;56-71.
32. Ransom R.W., Stec N.L. Cooperative modulation of (3H)MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines. J. Neurochem. 51:1988;830-836.
33. Reynolds I.J. Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. Eur. J. Pharmac. 177:1990;215-216.
34. Roberts A, Soffe S. R. and Dale N. (1986) Spinal interneurones and swimming in frog embryos. In Neurobiology of Vertebrate Locomotion (eds Grillner S., Stein P. S. G., Stuart D. G., Forssberg H. and Herman R. M.), pp. 279-306. MacMillan.
35. Soffe S.R., Roberts A. The influence of magnesium ion on the NMDA responses of ventral rhythmic neurons in the spinal cord of Xenopus embryos. Eur. J. Neurosci. 1:1989;507-515.
36. Sqalli-Houssaini Y., Cazalets J.-R., Clarac F. Oscillatory properties of the central pattern generator for locomotion in neonatal rats. J. Neurophysiol. 70:1993;803-813.
37. Sqalli-Houssaini Y., Cazalets J.-R., Clarac F. A cooling/heating system for use with in vitro preparation: study of temperature effects on newborn rat activities. J. Neurosci. Meth. 39:1991;131-139.
38. Thompson A.M. Glycine modulation of the NMDA receptor/channel complex. Trends Neurosci. 12:1989;349-353.
39. Turecek R., Vlachova V., Vyklicky L. Spontaneous openings of NMDA receptor channel in cultures rat hippocampal neurons. Eur. J. Neurosci. 9:1997;1999-2008.
40. Williams K. Interactions of polyamines with ion channels. Biochem. J. 325:1997;289-297.
41. Williams K., Dawson V.L., Romano C., Dichter M.A., Molinoff P.B. Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor. Neuron. 5:1990;199-208.
42. Woodward J.J. A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hippocampal slices. J. Neurochem. 62:1994;987-991.