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Volumn 69, Issue 5, 1997, Pages 2115-2122

Regulation of spontaneous activity of the δ-opioid receptor: Studies of inverse agonism in intact cells

Author keywords

Adenylyl cyclase; Inverse agonist; Opioid receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; CYCLIC AMP; DELTA OPIATE RECEPTOR; DIPRENORPHINE; DITERPENE; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; FORSKOLIN; LEUCINE ENKEPHALIN[2 DEXTRO SERINE 6 THREONINE]; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NALOXONE; NALTRINDOLE; OPIATE AGONIST; PERTUSSIS TOXIN;

EID: 0030826355     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69052115.x     Document Type: Article
Times cited : (48)

References (24)
  • 1
    • 0031032769 scopus 로고    scopus 로고
    • Human herpes virus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
    • Arvanitakis L., Geras-Raaka E., Varma A., Gershengorn M. C., and Cesarman E. (1997) Human herpes virus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 385, 347-350.
    • (1997) Nature , vol.385 , pp. 347-350
    • Arvanitakis, L.1    Geras-Raaka, E.2    Varma, A.3    Gershengorn, M.C.4    Cesarman, E.5
  • 2
    • 0029818288 scopus 로고    scopus 로고
    • Agonist activation of p42 and p44 mitogen-activated protein kinases following expression of the mouse δ opioid receptor in Rat-1 fibroblasts: Effects of receptor expression levels and comparisons with G-protein activation
    • Burt A. R., Carr I. C., Mullaney I., Anderson N. G., and Milligan G. (1996) Agonist activation of p42 and p44 mitogen-activated protein kinases following expression of the mouse δ opioid receptor in Rat-1 fibroblasts: effects of receptor expression levels and comparisons with G-protein activation. Biochem. J. 320, 227-235.
    • (1996) Biochem. J. , vol.320 , pp. 227-235
    • Burt, A.R.1    Carr, I.C.2    Mullaney, I.3    Anderson, N.G.4    Milligan, G.5
  • 5
    • 0030448770 scopus 로고    scopus 로고
    • Inverse agonistic effect of ICI174,864 on the cloned δ opioid receptor: Role of G protein and adenylyl cyclase activation
    • Chiu T. T., Yung L. Y., and Wong Y. H. (1996) Inverse agonistic effect of ICI174,864 on the cloned δ opioid receptor: role of G protein and adenylyl cyclase activation. Mol. Pharmacol. 50, 1651-1657.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1651-1657
    • Chiu, T.T.1    Yung, L.Y.2    Wong, Y.H.3
  • 6
    • 0001169515 scopus 로고
    • Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins
    • Costa T. and Herz A. (1989) Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. USA 86, 7321-7325.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7321-7325
    • Costa, T.1    Herz, A.2
  • 7
    • 0026608113 scopus 로고
    • Drug efficacy at guanine nucleotide-binding regulatory protein linked receptors: Thermodynamic interpretations of negative antagonism and of receptor activity in the absence of ligand
    • Costa T., Ogino Y., Munson P. J., Onaran O., and Rodbard D. (1992) Drug efficacy at guanine nucleotide-binding regulatory protein linked receptors: thermodynamic interpretations of negative antagonism and of receptor activity in the absence of ligand. Mol. Pharmacol. 41, 549-560.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 549-560
    • Costa, T.1    Ogino, Y.2    Munson, P.J.3    Onaran, O.4    Rodbard, D.5
  • 10
    • 0028950255 scopus 로고
    • The two-state model of receptor activation
    • Leff P. (1995) The two-state model of receptor activation. Trends Pharmacol. Sci. 16, 89-97.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 89-97
    • Leff, P.1
  • 11
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine-nucleotide regulatory proteins
    • Lefkowitz R. J., Cotecchia S., Samama P., and Costa T. (1993) Constitutive activity of receptors coupled to guanine-nucleotide regulatory proteins. Trends Pharmacol. Sci. 14, 303-308.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 303-308
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 12
    • 0030473469 scopus 로고    scopus 로고
    • 2-adrenoceptor in transfected neuroblastoma × glioma hybrid cells
    • 2-adrenoceptor in transfected neuroblastoma × glioma hybrid cells. Mol. Pharmacol. 50, 1479-1486.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1479-1486
    • MacEwan, D.J.1    Milligan, G.2
  • 13
    • 0029955446 scopus 로고    scopus 로고
    • Identification of the critical domains of the δ-opioid receptor involved in G protein coupling using site-specific synthetic peptides
    • Merkouris M., Dragatsis I., Megaritis G., Konidakis G., Zioudrou C., Milligan G., and Georgoussi Z. (1996) Identification of the critical domains of the δ-opioid receptor involved in G protein coupling using site-specific synthetic peptides. Mol. Pharmacol. 50, 985-993.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 985-993
    • Merkouris, M.1    Dragatsis, I.2    Megaritis, G.3    Konidakis, G.4    Zioudrou, C.5    Milligan, G.6    Georgoussi, Z.7
  • 14
    • 0023809133 scopus 로고
    • Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins
    • Milligan G. (1988) Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins. Biochem. J. 255, 1-13.
    • (1988) Biochem. J. , vol.255 , pp. 1-13
    • Milligan, G.1
  • 15
    • 0027484310 scopus 로고
    • Agonist regulation of cellular G protein levels and distribution: Mechanisms and functional implications
    • Milligan G. (1993) Agonist regulation of cellular G protein levels and distribution: mechanisms and functional implications. Trends Pharmacol. Sci. 14, 413-418.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 413-418
    • Milligan, G.1
  • 17
    • 0028861330 scopus 로고
    • Inverse agonism, pharmacological curiosity or potential therapeutic strategy
    • Milligan G., Bond R. A., and Lee M. (1995) Inverse agonism, pharmacological curiosity or potential therapeutic strategy. Trends Pharmacol. Sci. 16, 10-13.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 10-13
    • Milligan, G.1    Bond, R.A.2    Lee, M.3
  • 18
    • 0029958767 scopus 로고    scopus 로고
    • Analysis of inverse agonism at the δ opioid receptor after expression in Rat 1 fibroblasts
    • Mullaney I., Carr I. C., and Milligan G. (1996) Analysis of inverse agonism at the δ opioid receptor after expression in Rat 1 fibroblasts. Biochem. J. 315, 227-234.
    • (1996) Biochem. J. , vol.315 , pp. 227-234
    • Mullaney, I.1    Carr, I.C.2    Milligan, G.3
  • 19
    • 0026498187 scopus 로고
    • Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes
    • Richardson A., Demoliou-Mason C., and Barnard E. A. (1992) Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. Proc. Natl. Acad. Sci. USA 89, 10198-10202.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10198-10202
    • Richardson, A.1    Demoliou-Mason, C.2    Barnard, E.A.3
  • 22
    • 0028176054 scopus 로고
    • 2-adrenergic receptor activation of G proteins: Evidence for a precoupled receptor/G protein state
    • 2-adrenergic receptor activation of G proteins: evidence for a precoupled receptor/G protein state. Mol. Pharmacol. 45, 524-531.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 524-531
    • Tian, W.-N.1    Duzic, E.2    Lanier, S.M.3    Deth, R.C.4
  • 23
    • 0028671807 scopus 로고
    • i assays in transfected cells
    • i assays in transfected cells. Methods Enzymol. 238, 81-94.
    • (1994) Methods Enzymol. , vol.238 , pp. 81-94
    • Wong, Y.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.