Modulatory drug action in an allosteric Markov model of ion channel behaviour: biphasic effects with access-limited binding to either a stimulatory or an inhibitory site

Biochimica et Biophysica Acta - Biomembranes

Volumn 1372, Issue 1, 1998, Pages 37-44

  Yeo, Geoffrey F ^a   Madsen, Barry W ^b  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Burst behavior; Dual action; Nicotinic receptor; Non competitive inhibitor; Simulation and modelling

Indexed keywords

ION CHANNEL; NICOTINIC RECEPTOR;

ALLOSTERISM; ARTICLE; BINDING SITE; MATHEMATICAL MODEL; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR OCCUPANCY; SIMULATION;

EID: 0032562965     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(98)00025-X     Document Type: Article

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