A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein

Virology

Volumn 247, Issue 1, 1998, Pages 74-85

  Schilling, Boris ^a,c   De Medina, Tali ^a   Syken, Josh ^a   Vidal, Marc ^b   Münger, Karl ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c GIVAUDAN SCHWEIZ AG   (Switzerland)

^d Harvard Center for Cancer Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN;

ARTICLE; CHROMOSOME 16; DROSOPHILA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA; VIRUS REPLICATION; WART VIRUS;

DNA VIRUSES; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPES; POLYOMAVIRUS;

EID: 0032551661     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9220     Document Type: Article

References (70)

1. Altschul S. F., Madden T. L., Schaffer A. A., Zhang J., Zhang Z., Miller W., Lipman D. J. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25:1997;3389-3402.
2. Antinore M. J., Birrer M. J., Patel D., Nader L., McCance D. J. The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors. EMBO J. 15:1996;1950-1960.
3. Arroyo M., Bagchi S., Raychaudhuri P. Association of the human papillomavirus type 16 E7 protein with the S-phase specific E2F-cyclin A complex. Mol. Cell. Biol. 13:1993;6537-6546.
4. Baden H. P., Kvedar J. C. Epithelial cornified envelope precursors are in the hair follicle and nail. J. Invest. Dermatol. 101:1993;72S-74S.
5. Berezutskaya E., Bagchi S. The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome. J. Biol. Chem. 272:1997;30135-30140.
6. Blanton R. A., Coltrera M. D., Gown A. M., Halbert C. L., McDougall J. K. Expression of the HPV16 E7 gene generates proliferation in stratified squamous cell cultures which is independent of endogenous p53 levels. Cell Growth Differ. 3:1992;791-802.
7. Boyer S. N., Wazer D. E., Band V. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res. 56:1996;4620-4624.
8. Brodski J. Post-translational protein translocation: Not all hsc70s are created equal. Trends Biochem. Sci. 21:1996;121-126.
9. Brodsky J. L., Pipas J. M. Polyomavirus T antigens: Molecular chaperones for multiprotein complexes. J. Virol. 72:1998.
10. Campbell K. S., Mullane K. P., Aksoy I. A., Stubdal H., Zalvide J., Pipas J. M., Silver P. A., Roberts T. M., Schaffhausen B. S., DeCaprio J. A. DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev. 11:1997;1098-1110.
11. Cheetham M. E., Brion J.-P., Anderton B. H. Human homologues of the bacterial heat-shock protein DnaJ are preferentially expressed in neurons. Biochem. J. 284:1992;469-476.
12. Chellaiah A., Davis A., Mohanakumar T. Cloning of a unique human homologue of theEscherichia coli. Biochim. Biophys. Acta. 1174:1993;111-113.
13. Cheng S., Schmidt-Grimminger D. C., Murant T., Broker T. R., Chow L. T. Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev. 9:1995;2335-2349.
14. Chirgwin J. M., Przybyla A. E., MacDonald R. J., Rutter W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
15. Clemens K. E., Brent R., Gyuris J., Munger K. Dimerization of the human papillomavirus E7 oncoproteinin vivo. Virology. 214:1995;289-293.
16. Cyr D. M., Langer T., Douglas M. G. DnaJ-like proteins: Molecular chaperones and specific regulators of Hsp70. Trends Biochem. Sci. 19:1994;176-181.
17. DeCaprio J. A., Ludlow J. W., Lynch D., Furukawa Y., Griffin J., Piwnica-Worms H., Huang C. M., Livingston D. M. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell. 58:1989;1085-1095.
18. Defeo-Jones D., Vuocolo G. A., Haskell K. M., Hanobik M. G., Kiefer D. M., McAvoy E. M., Ivey-Hoyle M., Brandsma J. L., Oliff A., Jones R. E. Papillomavirus E7 protein binding to the retinoblastoma protein is not required for viral induction of warts. J. Virol. 67:1993;716-725.
19. Dyson N., Guida P., Münger K., Harlow E. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J. Virol. 66:1992;6893-6902.
20. Fearon E. R., Finkel T., Gillison M. L., Kennedy S. P., Casella J. F., Tomaselli G. F., Morrow J. S., Van D. C. Karyoplasmic interaction selection strategy: a general strategy to detect protein-protein interactions in mammalian cells. Proc. Natl. Acad. Sci. USA. 89:1992;7958-7962.
21. Funk J. O., Waga S., Harry J. B., Espling E., Stillman B., Galloway D. A. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11:1997;2090-2100.
22. Gateff E. Tumor suppressor and overgrowth suppressor genes ofDrosophila melanogaster: Int. J. Dev. Biol. 38:1994;565-590.
23. Georgopoulos C., Welch W. J. Role of the major heat shock proteins as molecular chaperones. Annu. Rev. Cell. Biol. 9:1993;601-634.
24. Gething M.-J., Sambrook J. Protein folding in the cell. Nature. 355:1992;33-44.
25. Harris K. F., Christensen J. B., Radany E. H., Imperiale M. J. Novel mechanisms of E2F induction by BK virus large-T antigen: Requirement of both the pRb binding and the J domains. Mol. Cell. Biol. 18:1998;1746-1756.
26. Haviv I., Vaizel D., Shaul Y. The X protein of hepatitis B virus coactivates potent activation domains. Mol. Cell. Biol. 15:1995;1079-1085.
27. Inoue A., Torigoe T., Sogahata K., Kamiguchi K., Takahashi S., Sawada Y., Saijo M., Taya Y., Ishii S., Sato N., Kikuchi K. 70-kDa heat shock cognate protein interacts directly with the N-terminal region of the retinoblastoma gene product pRb - Identification of a novel region of pRb-mediating protein interaction. J. Biol. Chem. 270:1995;22571-22576.
28. Jewers R. J., Hildebrandt P., Ludlow J. W., Kell B., McCance D. J. Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes. J. Virol. 66:1992;1329-1335.
29. Jones D. L., Münger K. Interactions of the human papillomavirus E7 protein with cell cycle regulators. Semin. Cancer Biol. 7:1996;327-337.
30. Cip1. Genes Dev. 11:1997a;2101-2111.
31. Jones D. L., Münger K. Analysis of the p53- mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein. J. Virol. 71:1997;2905-2912.
32. Jones D. L., Thompson D. A., Münger K. Destabilization of the RB tumor suppressor and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis. Virology. 239:1997b;97-107.
33. Kelley W. L., Georgopoulos C. The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of theEscherichia coli. Proc. Natl. Acad. Sci. USA. 94:1997;3679-3684.
34. Kelley W. L., Landry S. J. Chaperone power in a virus? Trends Biochem. Sci. 19:1994;277-278.
35. Kiyono T., Hiraiwa A., Fujita M., Hayashi Y., Akiyama T., Ishibashi M. Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. Proc. Natl. Acad. Sci. USA. 94:1997;11612-11616.
36. Kurzik-Dumke U., Gundacker D., Renthrop M., Gateff E. Tumor suppression in Drosophila is causally related to the function of the lethal(2) tumorous imaginal discs gene, a dnaJ homolog. Dev. Genet. 16:1995;64-76.
37. Kurzik-Dumke U., Phannavong B., Gundacker D., Gateff E. Genetic, cytogenetic and developmental analysis of theDrosophila melanogaster. Differentiation. 51:1992;91-104.
38. Lee D. H., Sherman M. Y., Goldberg A. L. Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins inSaccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;4773-4781.
39. Lee S. S., Weiss R. S., Javier R. T. Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein. Proc. Natl. Acad. Sci. USA. 94:1997;6670-6675.
40. Liberek K., Marszalek J., Ang D., Georgopoulos C., Zylicz M. Escherichia coli. Proc. Natl. Acad. Sci. USA. 88:1991;2874-2878.
41. Massimi P., Pim D., Storey A., Banks L. HPV-16 E7 and adenovirus E1a complex formation with TATA box binding protein is enhanced by casein kinase II phosphorylation. Oncogene. 1996;2325-2330.
42. Matsumine A., Ogai A., Senda T., Okumura N., Satoh K., Baeg G. H., Kawahara T., Kobayashi S., Okada M., Toyoshima K., Akiyama T. Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. Science. 272:1996;1020-1023.
43. Mazzarelli J. M., Atkins G. B., Geisberg J. V., Ricciardi R. P. The viral oncoproteins Ad5 E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110. Oncogene. 11:1995;1859-1864.
44. McIntyre M. C., Frattini M. G., Grossman S. R., Laimins L. A. Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding. J. Virol. 67:1993;3142-3150.
45. McIntyre M. C., Ruesch M. N., Laimins L. A. Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107. Virology. 215:1996;73-82.
46. Oh S., Iwahori A., Kato S. Human cDNA encoding DnaJ protein homologue. Biochim. Biophys. Acta. 1174:1993;114-116.
47. Ohtsuka K. Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ. Biochem. Biophys. Res. Commun. 197:1993;235-240.
48. +. Nature. 365:1993;664-666.
49. Patrick D. R., Oliff A., Heimbrook D. C. Identification of a novel retinoblastoma gene product binding site on human papillomavirus type 16 E7 protein. J. Biol. Chem. 269:1994;6842-6850.
50. Phelps W. C., Münger K., Yee C. L., Barnes J. A., Howley P. M. Structure-function analysis of the human papillomavirus E7 oncoprotein. J. Virol. 66:1992;2418-2427.
51. Phillips A. C., Vousden K. H. Analysis of the interaction between human papillomavirus type 16 E7 and the TATA-binding protein, TBP. J. Gen. Virol. 78:1997;905-909.
52. Polakis P. The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta. 1332:1997;F127-47.
53. Raabe T., Manley J. L. A human homologue of theEscherichia coli. Nucleic Acids Res. 19:1991;6645.
54. Sadowski I., Ma J., Triezenberg S., Ptashne M. GAL4-VP16 is an unusually potent transcriptional activator. Nature. 335:1988;563-564.
55. Sardet C., Vidal M., Cobrinik D., Geng Y., Onufryk C., Chen A., Weinberg R. A. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Natl. Acad. Sci. USA. 92:1995;2403-2407.
56. Sheng Q., Denis D., Ratnofsky M., Roberts T. M., DeCaprio J. A., Schaffhausen B. The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function. J. Virol. 71:1997;9410-9416.
57. Silver P. A., Way J. C. Eukaryotic dnaJ homologs and the specificity of hsp70 activity. Cell. 74:1993;5-6.
58. Srinivasan A., McClellan A. J., Vartikar J., Marks I., Cantalupo P., Li Y., Whyte P., Rundell K., Brodsky J. L., Pipas J. M. The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. Mol. Cell. Biol. 17:1997;4761-4773.
59. Stubdal H., Zalvide J., Campbell K. S., Schweitzer C., Roberts T. M., DeCaprio J. A. Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol. Cell. Biol. 17:1997;4979-4990.
60. Stubdal H., Zalvide J., Decaprio J. A. Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107. J. Virol. 70:1996;2781-2788.
61. Cell. 75:1993;1305-1315.
62. Tommasino M., Adamczewski J. P., Carlotti F., Barth C. F., Manetti R., Contorni M., Cavalieri F., Hunt T., Crawford L. HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A. Oncogene. 8:1993;195-202.
63. Tsai J., Douglas M. G. A conserved HPD sequence of the J-domain is necessary for YDJ1 stimulation of Hsp70 ATPase activity at a site distinct from substrate binding. J. Biol. Chem. 271:1996;9347-9354.
64. Vidal M. The reverse two-hybrid system. The Two-Hybrid System. 1997;Oxford Univ. Press, New York. p. 109-147.
65. Vidal M., Brachmann R. K., Fattaey A., Harlow E., Boeke J. D. Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions. Proc. Natl. Acad. Sci. USA. 93:1996;10315-10320.
66. Wu E. W., Clemens K. E., Heck D. V., Münger K. The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein. J. Virol. 67:1993;2402-2407.
67. Zalvide J., Stubdal H., DeCaprio J. A. The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins. Mol. Cell. Biol. 18:1998;1408-1415.
68. Zerfass-Thome K., Zwerschke W., Mannhardt B., Tindle R., Botz J. W., Jansen-Durr P. Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene. 13:1996;2323-2330.
69. zur Hausen H. Papillomavirus infections - A major cause of human cancers. Biochim. Biophys. Acta. 1288:1996;F55-F78.
70. Zwerschke W., Joswig S., Jansen Durr P. Identification of domains required for transcriptional activation and protein dimerization in the human papillomavirus type-16 E7 protein. Oncogene. 12:1996;213-220.