Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase

Journal of Biological Chemistry

Volumn 273, Issue 51, 1998, Pages 34164-34170

  Chen, Pei Feng ^a,b   Berka, Vladimir ^a   Tsai, Ah Lim ^a   Wu, Kenneth K ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; NITRIC OXIDE SYNTHASE;

AMINO ACID SUBSTITUTION; ARTICLE; BACULOVIRUS; BINDING SITE; COMPLEX FORMATION; DIMERIZATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE MUTATION; HEME SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MEDIATOR RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; ASPARTIC ACID; CARBON MONOXIDE; CATALYTIC DOMAIN; DNA PRIMERS; HEME; HUMANS; IMIDAZOLES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROPHOTOMETRY;

UNIDENTIFIED BACULOVIRUS;

EID: 0032545488     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.51.34164     Document Type: Article

References (33)

1. Nathan, C. F. (1992) FASEB J. 6, 3051-3064
2. Marletta, M. A. (1993) J. Biol. Chem. 268, 12231-12234
3. Stuehr, D. J., and Griffith, O. W. (1992) Adv. Enzymol. 65, 287-346
4. Förstermann, U., Schmidt, H. H. W., Pollock, J. S., Sheng, H., Mitchell, J. A., Warner, T. D., Nakane, M., and Murad, F. (1991) Biochem. Pharmacol. 42, 1849-1857
5. Pollock, J. S., Förstermann, U., Mitchell, J. A., Warner, T. D., Harald, H. H., Schmidt, H. H. H. W., Nakane, M., and Murad, F. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10480-10484
6. Bredt, D. S., and Snyder, S. H. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 682-685
7. Stuehr, D. J., Kwon, N. S., Nathan, C. F., Griffith, O. W., Feldman, P. L., and Wiseman, J. (1991) J. Biol. Chem. 266, 6259-6263
8. Stuehr, D. J., and Ikeda-Saito, M. (1992) J. Biol. Chem. 267, 20547-20550
9. McMillan, K., and Masters, B. S. S. (1993) Biochemistry 32, 9875-9880
10. McMillan, K., Bredt, D. S., Hirsch, D. J., Snyder, S. H., Clark, J. E., and Masters, B. S. S. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11141-11145
11. Chen, P.-F., Tsai, A.-L., and Wu, K. K. (1994) J. Biol. Chem. 269, 25062-25066
12. Dawson, J. H., and Sono, M. (1987) Chem. Rev. 87, 1255-1276
13. Salerno, J. C., Frey, C., McMillan, K., Williams, R. F., Masters, B. S. S., and Griffith, O. W. (1995) J. Biol. Chem. 270, 27423-27428
14. Matsuoka, A., Stuehr, D. J., Olson, J. S., Clark, P., and Ikeda-Saito, M. (1994) J. Biol. Chem. 269, 20335-20339
15. Migita, C. T., Salerno, J. C., Masters, B. S. S., Martasek, P., McMillan, K., and Ikeda-Saito, M. (1997) Biochemistry 36, 10987-10992
16. Chen, P.-F., Tsai, A.-L., Berka, V., and Wu, K. K. (1997) J. Biol. Chem. 272, 6114-6118
17. Gachhui, R., Ghosh, D. K., Wu, C., Parkinson, J., Crane, B. R., and Stuehr, D. (1997) Biochemistry 36, 5097-5103
18. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
19. Chen, P.-F., Tsai, A.-L., and Wu, K. K. (1995) Biochem. Biophys. Res. Commun. 215, 1119-1129
20. Chen, P.-F., Tsai, A.-L., Berka, V., and Wu, K. K. (1996) J. Biol. Chem. 271, 14631-14635
21. Schmidt, H. H. H. W., Smith, R. W., Nakane, M., and Murad, F. (1992) Biochemistry 31, 3243-3249
22. Chabin, R. M., McCauley, E., Calaycay, J. R., Kelly, T. M., MacNaul, K. L., Wolfe, G. C., Hutchinson, N. I., Madhusudanaraju, S., Schmidt, J. A., Kozarich, J. W., and Wong, K. K. (1996) Biochemistry 35, 9567-9575
23. Berka, V., Chen, P.-F., and Tsai, A.-L. (1996) J. Biol. Chem. 271, 33293-33300
24. Dawson, J. H., Andersson, L. A., and Sono, M. (1982) J. Biol. Chem. 257, 3606-3617
25. Sono, M., and Dawson, J. H. (1982) J. Biol. Chem. 257, 5496-5502
26. Crane, B. R., Arvai, A. S., Ghosh, D. K., Wu, C., Getzoff, E. D., Stuehr, D. J., and Tainer, J. A. (1998) Science 279, 2121-2126
27. Masters, B. S. S., Raman, C. S., Li, H., Martasek, P., Kral, V., and Poulos, T. L. (1998) ASBMB Meeting, May 16-20, 1998, Washington, D. C., Abstr. LB 97
28. Mayer, B., Wu, C., Gorren, A. C., Pfeifler, S., Schmidt, K., Clark P., Stuehr, D. J., and Werner, E. R. (1997) Biochemistry 36, 8422-8427
29. Presta, A., Siddhanta, U., Wu, C., Sennequier, N., Huang, L., Abu-Soud, H. M., Erzurum, S., and Stuehr, D. J. (1998) Biochemistry 37, 298-310
30. Wang, J., Stuehr, D. J., and Rousseau, D. L (1995) Biochemistry 34, 7080-7087
31. Janssens, S. P., Shimouchi, A., Quertermous, T., Bloch, D. B., and Bloch, K. D. (1992) J. Biol. Chem. 267, 14519-14522
32. Nakane, M., Schmidt, H. H., Pollock, J. S., Förstermann, U., and Murad, F. (1993) FEBS Lett. 316, 175-180
33. Geller, D. A., Lowenstein, C. J., Shapiro, R. A., Nussler, A. K., Di Silvio, M., Wang, S. C., Nakayama, D. K., Simmons, R. L., Snyder, S. H., and Billiar, T. R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3491-3495