Solid-phase synthesis and encoding strategies for olefin polymerization catalyst libraries

Angewandte Chemie - International Edition

Volumn 37, Issue 23, 1998, Pages 3272-3275

  Boussie, Thomas R ^a   Coutard, Carla ^a   Turner, Howard ^a   Murphy, Vince ^a   Powers, Timothy S ^a  

^a SYMYX TECHNOLOGIES   (United States)

Author keywords

Combinatorial chemistry; Heterogeneous catalysis; Polymers; Solid phase synthesis

Indexed keywords

ALKENE; NICKEL; ORGANOMETALLIC COMPOUND; PALLADIUM; POLYMER;

ARTICLE; CATALYST; CHEMICAL STRUCTURE; COMPLEX FORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLYMERIZATION; SYNTHESIS;

EID: 0032542316     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19981217)37:23<3272::AID-ANIE3272>3.0.CO;2-R     Document Type: Article

References (39)

1. a) N. K. Terrett, M. Gardner, D. W. Gordon, R. J. Kobylecki, J. Steele, Tetrahedron 1995, 30, 8135-8173;
2. b) E. M. Gordon, M. A. Gallop, D. V. Patel, Acc. Chem. Res. 1996, 29, 144-154.
3. a) X.-D. Xiang, X. S. Sun, G. Briceno, Y. Lou, K.-A. Wang, H. Chang, W. G. Wallace-Freedman, S.-W. Chen, P. G. Schultz, Science 1995, 268, 1738-1740;
4. b) G. Briceño, H. Chang, X. Sun, P. G. Schultz, S.-W. Chen, Science 1995, 270, 273-275;
5. c) K. Burgess, D. Moye-Sherman, A. M. Porte in Molecular Diversity Combinatorial Chemistry: Library Drug Discovery (Eds.: I. M. Irwin, K. D. Janda), American Chemical Society, Washington, DC, 1996, pp. 128-136;
6. d) K. Burgess, A.M. Porte, Adv. Catal. Processes 1997, 2, 69-82;
7. e) E. Danielson, J. H. Golden, E. McFarland, C. M. Reaves, W. H. Weinberg, X. D. Wu, Nature 1997, 389, 944-948;
8. f) H. W. Weinberg, B. Jandeleit, K. Self, H. Turner, Cnrr. Opin. Solid State Mater. Sci. 1998, 3, 104-110.
9. a) K. Burgess, H.-J. Lim, A. M. Porte, G. A. Sulikowski, Angew. Chem. 1996, 108, 192-194;
10. Angew. Chem. Int. Ed. Engl. 1996, 35, 220-222;
11. b) K. D. Shimuzu, B. M. Cole, C. A. Krueger, K. W. Kuntz, M. L. Snapper, A. H. Hoveyda, Angew. Chem. 1997, 109, 1784-1785;
12. Angew. Chem. Int. Ed. Engl. 1997, 36, 1700-1702;
13. c) S. R. Gilbertson, X. Wang, Tetrahedron Lett. 1996, 37, 6475-6478;
14. d) G. Lui, J. A. Ellman, J. Org. Chem. 1995, 60, 7712-7713;
15. e) M. S. Sigman, E. N. Jacobsen, J. Am. Chem. Soc. 1998, 110, 4901-4902;
16. f) M. B. Francis, N. S. Finney, E. N. Jacobsen, J. Am. Chem. Soc. 1996, 118, 8983-8984.
17. N. Kashiwa, J. Imuta, Catal. Surv. Jpn. 1997, 1, 125-142.
18. a) L. Sun, A. Shariati, J. C. Hsu, D. W. Bacon, Stud. Surf. Sci. Catal. 1994, 89, 81-89;
19. b) L. Sun, C. C. Hsu, D. W. Bacon, J. Polym. Sci. Part A 1994, 32, 2127-2134.
20. S. B. Roscoe, J. M. Fréchet, J. F. Walzer, A. J. Dias, Science 1998, 280, 270-273.
21. a) F. Balkenhohl, C. von dem Bussche-Hünnefeld, A. Lansky, C. Zechel, Angew. Chem. 1996, 108, 2436-2488;
22. Angew. Chem. Int. Ed. Engl. 1996, 35, 2288-2337;
23. b) J. S. Früchtel, G. Jung, Angew. Chem. 1996, 108, 19-46;
24. Angew. Chem. Int. Ed. Engl. 1996, 35, 17-42;
25. c) L. A. Thompson, J. Ellman, Chem. Rev. 1996, 96, 555-600;
26. d) P. H. H. Hermkens, H. C. J. Ottenheijm, D. Rees, Tetrahedron 1996, 52, 4527-4554;
27. e) S. J. Shuttleworth, S. M. Allin, P. K. Sharma, Synthesis 1997, 1217-1239.
28. a) L. K. Johnson, C. M. Killian, M. Brookhart, J. Am. Chem. Soc. 1995, 117, 6414-6415;
29. b) C.M. Killian, L. K. Johnson, M. Brookhart, Organometallics 1997, 16, 2005-2007;
30. c) B. L. Small, M. Brookhart, A. M. A. Bennett, J. Am. Chem. Soc. 1998, 120, 4049-4050;
31. d) G. J. P. Britovsek, V. C. Gibson, B. S. Kimberly, P. J. Maddox, S. J. McTavish, G. A. Solan, A. J. P. White, D. J. Williams, Chem. Commun. 1998, 849-850.
32. L. K. Johnson, S. Mecking, M. Brookhart, J. Am. Chem. Soc. 1996, 118, 267-268.
33. W. H. Weinberg, E. McFarland, I. Goldwasser, T. Bousie, H. Turner, J. A. M. van Beek, V. Murphy, T. Powers (Symyx Technologies), WO-A 98/03521,1998.
34. N. DeKimpe, L. D'Hondt, E. Stanoeva, Tetrahedron Lett. 1991, 32, 3879-3882.
35. a) D. Maclean, J. R. Schullek, M. M. Murphy, Z. J. Ni, E. M. Gordon, M. A. Gallop, Proc. Natl. Acad. SCi. USA 1997, 94, 2805-2810;
36. b) Z. J. Ni, D. Maclean, C. P. Holmes, B. Ruhland, M. M. Murphy, J. W. Jacobs, E. M. Gordon, M. A. Gallop, J. Med. Chem. 1996, 39, 1601-1608.
37. Review on encoding strategies: A. W. Czarnik, Curr. Opin. Chem. Biol. 1997, 1, 60-66, and references therein.
38. The method employed was similar to that described in P. Conti, D. Demont, J. Cals, H. Ottenheijm, D. Leysen, Tetrahedron Lett. 1997, 38, 2915-2918.
39. The tagged catalysts were also run separately to assess relative performance trends.