-
1
-
-
0028243847
-
Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries
-
Gallop MA, Barrett RW, Dower WJ, Fodor SPA, Gordon EM. Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries. J Med Chem. 37:1994;1233-1251.
-
(1994)
J Med Chem
, vol.37
, pp. 1233-1251
-
-
Gallop, M.A.1
Barrett, R.W.2
Dower, W.J.3
Fodor, S.P.A.4
Gordon, E.M.5
-
2
-
-
0028318863
-
Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions
-
Gordon EM, Barrett RW, Dower WJ, Fodor SPA, Gallop MA. Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions. J Med Chem. 37:1994;1385-1401.
-
(1994)
J Med Chem
, vol.37
, pp. 1385-1401
-
-
Gordon, E.M.1
Barrett, R.W.2
Dower, W.J.3
Fodor, S.P.A.4
Gallop, M.A.5
-
5
-
-
7044263277
-
Synthesis and applications of small molecule libraries
-
Thompson LA, Ellman JA. Synthesis and applications of small molecule libraries. Chem Rev. 96:1996;555-600.
-
(1996)
Chem Rev
, vol.96
, pp. 555-600
-
-
Thompson, L.A.1
Ellman, J.A.2
-
6
-
-
33748844784
-
Combinatorial libraries: Studies in molecular recognition and the quest for new vatalysts
-
Gennari C, Nestler HP, Piarulli U, Salom B. Combinatorial libraries: studies in molecular recognition and the quest for new vatalysts. Liebigs Ann/Recueil. 1997;637-647.
-
(1997)
Liebigs Ann/Recueil
, pp. 637-647
-
-
Gennari, C.1
Nestler, H.P.2
Piarulli, U.3
Salom, B.4
-
7
-
-
0000577984
-
The "one-bead-one-compound" combinatorial library method
-
Lam KS, Lebl M, Krchnák V. The "one-bead-one-compound" combinatorial library method. Chem Rev. 97:1997;411-448.
-
(1997)
Chem Rev
, vol.97
, pp. 411-448
-
-
Lam, K.S.1
Lebl, M.2
Krchnák, V.3
-
8
-
-
0001070152
-
Spatially addressable combinatorial libraries
-
Pirrung MC. Spatially addressable combinatorial libraries. Chem Rev. 9:1997;473-488.
-
(1997)
Chem Rev
, vol.9
, pp. 473-488
-
-
Pirrung, M.C.1
-
9
-
-
0029325254
-
A combinatorial approach to materials discovery
-
Xiang X-D, Sun X, Briceno G, Lou Y, Wang K-A, Chang H, Wallace-Freedman WG, Chen S-W, Schultz PG. A combinatorial approach to materials discovery. Science. 268:1995;1738-1740.
-
(1995)
Science
, vol.268
, pp. 1738-1740
-
-
Xiang X-D1
Sun, X.2
Briceno, G.3
Lou, Y.4
Wang K-A5
Chang, H.6
Wallace-Freedman, W.G.7
Chen S-W8
Schultz, P.G.9
-
10
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0029388980
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A class of cobalt oxide magnetoresistance materials discovered with combinatorial synthesis
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Briceno G, Chang H, Sun X, Schultz PG, Xiang X-D. A class of cobalt oxide magnetoresistance materials discovered with combinatorial synthesis. Science. 270:1995;273-275.
-
(1995)
Science
, vol.270
, pp. 273-275
-
-
Briceno, G.1
Chang, H.2
Sun, X.3
Schultz, P.G.4
Xiang X-D5
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12
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0029175021
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Identification of technetium-99m binding peptides using combinatorial cellulose-bound peptide libraries
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Malin R, Steinbrecher R, Jannsen J, Semmler W, Noll B, Johannsen B, Frömmel C, Höhne W, Schneider-Mergener J. Identification of technetium-99m binding peptides using combinatorial cellulose-bound peptide libraries. J Am Chem Soc. 117:1995;11821-11822.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 11821-11822
-
-
Malin, R.1
Steinbrecher, R.2
Jannsen, J.3
Semmler, W.4
Noll, B.5
Johannsen, B.6
Frömmel, C.7
Höhne, W.8
Schneider-Mergener, J.9
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13
-
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10244273514
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A general solid-phase synthesis strategy for the preparation of 2-pyrrolidinemethanol ligands
-
Liu G, Ellman JA. A general solid-phase synthesis strategy for the preparation of 2-pyrrolidinemethanol ligands. J Org Chem. 60:1995;7712-7713.
-
(1995)
J Org Chem
, vol.60
, pp. 7712-7713
-
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Liu, G.1
Ellman, J.A.2
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14
-
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0000596050
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Phosphatase catalysis via combinatorial organic chemistry
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Menger FM, Eliseev AV, Migulin VA. Phosphatase catalysis via combinatorial organic chemistry. J Org Chem. 60:1995;6666-6661.
-
(1995)
J Org Chem
, vol.60
, pp. 6666-6661
-
-
Menger, F.M.1
Eliseev, A.V.2
Migulin, V.A.3
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15
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0029811207
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Combinatorial approach to the discovery of novel coordination complexes
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Francis MB, Finney NS, Jacobsen EN. Combinatorial approach to the discovery of novel coordination complexes. J Am Chem Soc. 118:1996;8983-8984.
-
(1996)
J Am Chem Soc
, vol.118
, pp. 8983-8984
-
-
Francis, M.B.1
Finney, N.S.2
Jacobsen, E.N.3
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16
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0027362628
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Complex synthetic chemical libraries indexed with molecular tags
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Ohlmeyer MHJ, Swanson RN, Dillard LW, Reader JC, Asouline G, Kobayashi R, Wigler M, Still WC. Complex synthetic chemical libraries indexed with molecular tags. Proc Natl Acad Sci USA. 90:1993;10922-10926.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10922-10926
-
-
Ohlmeyer, M.H.J.1
Swanson, R.N.2
Dillard, L.W.3
Reader, J.C.4
Asouline, G.5
Kobayashi, R.6
Wigler, M.7
Still, W.C.8
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17
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0025893762
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General method for rapid synthesis of multicomponent peptide mixtures
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Furka A, Sebestyen F, Asgedom M, Dibo G. General method for rapid synthesis of multicomponent peptide mixtures. Int J Pept Prot Res. 37:1991;487-493.
-
(1991)
Int J Pept Prot Res
, vol.37
, pp. 487-493
-
-
Furka, A.1
Sebestyen, F.2
Asgedom, M.3
Dibo, G.4
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19
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0029061291
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Enantioselective synthesis of a 1,2-disubstituted mitosene by a copper-catalyzed intramolecular carbon-hydrogen insertion reaction of a diazoester
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Lim H-J, Sulikowski GA. Enantioselective synthesis of a 1,2-disubstituted mitosene by a copper-catalyzed intramolecular carbon-hydrogen insertion reaction of a diazoester. J Org Chem. 60:1995;2326-2327.
-
(1995)
J Org Chem
, vol.60
, pp. 2326-2327
-
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Lim H-J1
Sulikowski, G.A.2
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20
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0000038848
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New catalysts and conditions for a C-H insertion reaction identified by high throughput catalyst screening
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This article is significant in that the application of a combinatorial method to the optimization of known catalyst systems led to the discovery of a catalyst.
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Burgess K, Lim H-J, Porte AM, Sulikowski GA. New catalysts and conditions for a C-H insertion reaction identified by high throughput catalyst screening. Angew Chem. 108:1996;192-194. This article is significant in that the application of a combinatorial method to the optimization of known catalyst systems led to the discovery of a catalyst.
-
(1996)
Angew Chem
, vol.108
, pp. 192-194
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Burgess, K.1
Lim H-J2
Porte, A.M.3
Sulikowski, G.A.4
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21
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33748247343
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New catalysts and conditions for a C-H insertion reaction identified by high throughput catalyst screening
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This article is significant in that the application of a combinatorial method to the optimization of known catalyst systems led to the discovery of a catalyst. Int Ed Engl
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Burgess K, Lim H-J, Porte AM, Sulikowski GA. New catalysts and conditions for a C-H insertion reaction identified by high throughput catalyst screening. Int Ed Engl Angew Chem. 35:1996;220-222 This article is significant in that the application of a combinatorial method to the optimization of known catalyst systems led to the discovery of a catalyst.
-
(1996)
Angew Chem
, vol.35
, pp. 220-222
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Burgess, K.1
Lim H-J2
Porte, A.M.3
Sulikowski, G.A.4
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22
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84989562269
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Ring-opening reactions of epoxides with trimethylsilyl cyanide catalyzed by titanium alkoxide-Schiff base complexes
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Hayashi M, Tamura M, Oguni N. Ring-opening reactions of epoxides with trimethylsilyl cyanide catalyzed by titanium alkoxide-Schiff base complexes. Synlett. 1992;663-664.
-
(1992)
Synlett
, pp. 663-664
-
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Hayashi, M.1
Tamura, M.2
Oguni, N.3
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23
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0001019669
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Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides
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The authors effectively demonstrated that a modular approach to ligand modification coupled with a "positional scanning" screening method could be applied to catalysis.
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Cole BM, Shimizu KD, Krueger CA, Harrity JPA, Snapper ML, Hoveyda AH. Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides. Angew Chem. 108:1996;1776-1779. The authors effectively demonstrated that a modular approach to ligand modification coupled with a "positional scanning" screening method could be applied to catalysis.
-
(1996)
Angew Chem
, vol.108
, pp. 1776-1779
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Cole, B.M.1
Shimizu, K.D.2
Krueger, C.A.3
Harrity, J.P.A.4
Snapper, M.L.5
Hoveyda, A.H.6
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24
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0029764025
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Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides
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The authors effectively demonstrated that a modular approach to ligand modification coupled with a "positional scanning" screening method could be applied to catalysis. Int Ed Engl
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Cole BM, Shimizu KD, Krueger CA, Harrity JPA, Snapper ML, Hoveyda AH. Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides. Int Ed Engl Angew Chem. 35:1996;1668-1671 The authors effectively demonstrated that a modular approach to ligand modification coupled with a "positional scanning" screening method could be applied to catalysis.
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(1996)
Angew Chem
, vol.35
, pp. 1668-1671
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Cole, B.M.1
Shimizu, K.D.2
Krueger, C.A.3
Harrity, J.P.A.4
Snapper, M.L.5
Hoveyda, A.H.6
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25
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0000422388
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Search for chiral catalysts through ligand diversity: Substrate-specific catalysts and ligand screening on solid phase
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Shimizu KD, Cole BM, Krueger CA, Kuntz KW, Snapper ML, Hoveyda AH. Search for chiral catalysts through ligand diversity: substrate-specific catalysts and ligand screening on solid phase. Angew Chem. 109:1997;1784-1785.
-
(1997)
Angew Chem
, vol.109
, pp. 1784-1785
-
-
Shimizu, K.D.1
Cole, B.M.2
Krueger, C.A.3
Kuntz, K.W.4
Snapper, M.L.5
Hoveyda, A.H.6
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26
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0030766272
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Search for chiral catalysts through ligand diversity: Substrate-specific catalysts and ligand screening on solid phase
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Int Ed Engl
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Shimizu KD, Cole BM, Krueger CA, Kuntz KW, Snapper ML, Hoveyda AH. Search for chiral catalysts through ligand diversity: substrate-specific catalysts and ligand screening on solid phase. Int Ed Engl Angew Chem. 36:1997;1700-1702.
-
(1997)
Angew Chem
, vol.36
, pp. 1700-1702
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Shimizu, K.D.1
Cole, B.M.2
Krueger, C.A.3
Kuntz, K.W.4
Snapper, M.L.5
Hoveyda, A.H.6
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27
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0030565556
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The combinatorial synthesis of chiral phosphine ligands
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Gilbertson SR, Wang X. The combinatorial synthesis of chiral phosphine ligands. Tetrahedron Lett. 37:1996;6475-6478.
-
(1996)
Tetrahedron Lett
, vol.37
, pp. 6475-6478
-
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Gilbertson, S.R.1
Wang, X.2
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28
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0030599601
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The first combinatorially prepared and evaluated inorganic catalysts. Polyoxymetalates for the aerobic oxidation of the mustard analog tetrahydrothiophene (THT)
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Hill CL, Gall RD. The first combinatorially prepared and evaluated inorganic catalysts. Polyoxymetalates for the aerobic oxidation of the mustard analog tetrahydrothiophene (THT). J Mol Cat A. 114:1996;103-111.
-
(1996)
J Mol Cat a
, vol.114
, pp. 103-111
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Hill, C.L.1
Gall, R.D.2
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29
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0040432653
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Discovery of methanol electro-oxidation catalysts by combinatorial analysis
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This contribution is unique in that an indirect and highly parallelizable method for monitoring electrochemical events was disclosed.
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Mallouk TE, Reddington E, Pu C, Ley KL, Smotkin ES. Discovery of methanol electro-oxidation catalysts by combinatorial analysis. Extended Abstracts; Fuel Cell Seminar: Orlando, Florida. 1996;686-689 This contribution is unique in that an indirect and highly parallelizable method for monitoring electrochemical events was disclosed.
-
(1996)
Extended Abstracts; Fuel Cell Seminar: Orlando, Florida
, pp. 686-689
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Mallouk, T.E.1
Reddington, E.2
Pu, C.3
Ley, K.L.4
Smotkin, E.S.5
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30
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0030399120
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Infrared thermographic screening of combinatorial libraries of heterogeneous catalysts
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Moates FC, Somani M, Annamalai J, Richardson JT, Luss D, Willson RC. Infrared thermographic screening of combinatorial libraries of heterogeneous catalysts. Ind Eng Chem Res. 35:1996;4801-4803.
-
(1996)
Ind Eng Chem Res
, vol.35
, pp. 4801-4803
-
-
Moates, F.C.1
Somani, M.2
Annamalai, J.3
Richardson, J.T.4
Luss, D.5
Willson, R.C.6
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31
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0031259576
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A combinatorial approach to the discovery and optimization of luminescent materials
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This ppaer describes the efficient synthesis of a thin film library containing 26,000 compositions on a three inch silicon wafer. Although no catalytic chemistry was reported, it is significant in that the same group has demonstrated that thin film libraries can be screened for catalytic activity and selectivity using a scanning mass spectrometer.
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Danielson E, Golden JH, McFarland E, Reaves CM, Weinberg WH, Wu XD. A combinatorial approach to the discovery and optimization of luminescent materials. Nature. 389:1997;944-948 This ppaer describes the efficient synthesis of a thin film library containing 26,000 compositions on a three inch silicon wafer. Although no catalytic chemistry was reported, it is significant in that the same group has demonstrated that thin film libraries can be screened for catalytic activity and selectivity using a scanning mass spectrometer.
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(1997)
Nature
, vol.389
, pp. 944-948
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Danielson, E.1
Golden, J.H.2
McFarland, E.3
Reaves, C.M.4
Weinberg, W.H.5
Wu, X.D.6
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32
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0030880103
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High-speed materials design
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Service RF. High-speed materials design. Science. 277:1997;474-475.
-
(1997)
Science
, vol.277
, pp. 474-475
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Service, R.F.1
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33
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0039248095
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A combinatorial chemistry approach to oxidation catalyst discovery and optimization
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Cong P, Giaquinta D, Guan S, McFarland E, Self K, Turner HW, Weinberg WH. A combinatorial chemistry approach to oxidation catalyst discovery and optimization. Proc Ann AlChE Meeting, New Orleans, LA. 1998; This article describes the first serious effort to develop combinatorial methods of discovering and optimizing heterogeneous catalysts that integrate automated synthesis, screening, and informatics.
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(1998)
Proc Ann AlChE Meeting, New Orleans, la
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Cong, P.1
Giaquinta, D.2
Guan, S.3
McFarland, E.4
Self, K.5
Turner, H.W.6
Weinberg, W.H.7
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