Use of engineered ribozymes to catalyze chimeric gene assembly

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 15, 1996, Pages 7486-7490

  Mikheeva, Svetlana ^a   Jarrell, Kevin A ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

exon shuffling; gene engineering; group II intron; intron splicing; tissue plasminogen activator

Indexed keywords

MESSENGER RNA; RECOMBINANT RNA; RIBOZYME; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; BINDING SITE; DNA SEQUENCE; ENZYME MODIFICATION; EXON; GENE CASSETTE; GENE INSERTION; GENETIC ENGINEERING; HUMAN; INTRON; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SITE DIRECTED MUTAGENESIS;

BASE SEQUENCE; DNA PRIMERS; EPIDERMAL GROWTH FACTOR; EXONS; FIBRONECTINS; GENETIC ENGINEERING; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; RESTRICTION MAPPING; RNA SPLICING; RNA, CATALYTIC; RNA, MESSENGER; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION, GENETIC;

EID: 0029795237     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.15.7486     Document Type: Article

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