Functional interactions between the Holliday junction resolvase and the branch migration motor of Escherichia coli

EMBO Journal

Volumn 17, Issue 6, 1998, Pages 1838-1845

  Van Gool, Alain J ^a   Shah, Rajvee ^a,b   Mézard, Christine ^a,c   West, Stephen C ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c INSTITUT CURIE   (France)

Author keywords

DNA helicase; DNA repair; Protein DNA interactions; Recombination; Resolution

Indexed keywords

ENDONUCLEASE; HELICASE; RESOLVASE;

ARTICLE; DNA RECOMBINATION; DNA REPAIR; ESCHERICHIA COLI; HOLLIDAY JUNCTION; NONHUMAN; PRIORITY JOURNAL;

BACTERIAL PROTEINS; DNA; DNA HELICASES; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; NUCLEIC ACID CONFORMATION; RECOMBINATION, GENETIC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0032536901     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.6.1838     Document Type: Article

References (42)

1. Ariyoshi, M., Vassylyev, D.G., Iwasaki, H., Nakamura, H., Shinagawa, H. and Morikawa, K. (1994) Atomic structure of the RuvC resolvase: A Holliday junction-specific endonuclease from E.coli. Cell, 78, 1063-1072.
2. Baumann, P., Benson, F.E. and West, S.C. (1996) Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell, 87, 757-766.
3. Bennett, R.J. and West, S.C. (1995) Structural analysis of the RuvC-Holliday junction complex reveals an unfolded junction. J. Mol. Biol., 252, 213-226.
4. Bennett, R.J. and West, S.C. (1996) Resolution of Holliday junctions in genetic recombination: RuvC protein nicks DNA at the point of strand exchange. Proc. Natl Acad. Sci. USA, 93, 12217-12222.
5. Bennett, R.J., Dunderdale, H.J. and West, S.C. (1993) Resolution of Holliday junctions by RuvC resolvase: Cleavage specificity and DNA distortion. Cell, 74, 1021-1031.
6. Dunderdale, H.J., Benson, F.E., Parsons, C.A., Sharples, G.J., Lloyd, R.G. and West, S.C. (1991) Formation and resolution of recombination intermediates by E.coli RecA and RuvC proteins. Nature, 354, 506-510.
7. Dunderdale, H.J., Sharples, G.J., Lloyd, R.G. and West, S.C. (1994) Cloning, over-expression, purification and characterization of the Escherichia coli RuvC Holliday junction resolvase. J. Biol. Chem., 269, 5187-5194.
8. Eggleston, A.K., Mitchell, A.H. and West, S.C. (1997) In vitro reconstitution of the late steps of genetic recombination in E.coli. Cell, 89, 607-617.
9. Hyde, H., Davies, A.A., Benson, F.E. and West, S.C. (1994) Resolution of recombination intermediates by a mammalian endonuclease activity functionally analogous to Escherichia coli RuvC resolvase. J. Biol. Chem., 269, 5202-5209.
10. Iwasaki, H., Takahagi, M., Shiba, T., Nakata, A. and Shinagawa, H. (1991) Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure. EMBO J., 10, 4381-4389.
11. Kowalczykowski, S.C., Dixon, D.A., Eggleston, A.K., Lauder, S.D. and Rehrauer, W.M. (1994) Biochemistry of homologous recombination in Escherichia coli. Microbiol. Rev., 58, 401-465.
12. Lloyd, R.G. and Low, K.B. (1996) Homologous recombination. In Neidhardt, F.C. (ed.), Escherichia coli and Salmonella: Cellular and Molecular Biology. ASM Press, Washington DC, pp. 2236-2255.
13. Lloyd, R.G., Benson, F.E. and Shurvinton, C.E. (1984) Effect of ruv mutations on recombination and DNA repair in Escherichia coli K12. Mol. Gen. Genet., 194, 303-309.
14. Mandal, T.N., Mahdi, A.A., Sharples, G.J. and Lloyd, R.G. (1993) Resolution of Holliday intermediates in recombination and DNA repair: indirect suppression of ruvA, ruvB, and ruvC mutations. J. Bacteriol., 175, 4325-4334.
15. Maxam, A.M. and Gilbert, W. (1980) Sequencing end-labeled DNA with base specific chemical cleavages. Meth. Enzymol., 65, 499-560.
16. D113N. A mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities. J. Mol. Biol., 271, 704-717.
17. Mitchell, A.H. and West, S.C. (1996) Role of RuvA in branch migration reactions catalyzed by the RuvA and RuvB proteins of Escherichia coli. J. Biol. Chem., 271, 19497-19502.
18. Muller, B., Tsaneva, I.R. and West, S.C. (1993) Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins: I. Comparison of the RuvAB-and RuvB-mediated reactions. J. Biol. Chem., 268, 17179-17184.
19. Ogawa, T., Shinohara, A., Nabetani, A., Ikeya, T., Yu, X., Egelman, E.H. and Ogawa, H. (1993a) RecA-like recombination proteins in eukaryotes: functions and structures of RAD51 genes. Cold Spring Harb. Symp. Quant. Biol., 58, 567-576.
20. Ogawa, T., Yu, X., Shinohara, A. and Egelman, E.H. (1993b) Similarity of the yeast Rad51 filament to the bacterial RecA filament. Science, 259, 1896-1899.
21. Panyutin, I.G. and Hsieh, P. (1993) Formation of a single base mismatch impedes spontaneous DNA branch migration. J. Mol. Biol., 238, 413-424.
22. Panyutin, I.G. and Hsieh, P. (1994) The kinetics of spontaneous DNA branch migration. Proc. Natl Acad. Sci. USA, 91, 2021-2025.
23. Parsons, C.A. and West, S.C. (1993) Formation of a RuvAB-Holliday junction complex in vitro. J. Mol. Biol., 232, 397-405.
24. Parsons, C.A., Kemper, B. and West, S.C. (1990) Interaction of a four-way junction in DNA with T4 endonuclease VII. J. Biol. Chem., 265, 9285-9289.
25. Parsons, C.A., Tsaneva, I., Lloyd, R.G. and West, S.C. (1992) Interaction of Escherichia coli RuvA and RuvB proteins with synthetic Holliday junctions. Proc. Natl Acad. Sci. USA, 89, 5452-5456.
26. Parsons, C.A., Stasiak, A., Bennett, R.J. and West, S.C. (1995) Structure of a multisubunit complex that promotes DNA branch migration. Nature, 374, 375-378.
27. Rafferty, J.B., Sedelnikova, S.E., Hargreaves, D., Artymiuk, P.J., Baker, P.J., Sharples, G.J., Mahdi, A.A., Lloyd, R.G. and Rice, D.W. (1996) Crystal structure of the DNA recombination protein RuvA and a model for its binding to the Holliday junction. Science, 274, 415-421.
28. Rhodes, D. and Fairall, L. (1997). Analysis of sequence-specific DNA binding proteins. In Creighton, T.E. (ed.), Protein Function: A Practical Approach. Oxford University Press, Oxford, pp. 215-244.
29. Shah, R., Bennett, R.J. and West, S.C. (1994a) Activation of RuvC Holliday junction resolvase in vitro. Nucleic Acids Res., 22, 2490-2497.
30. Shah, R., Bennett, R.J. and West, S.C. (1994b) Genetic recombination in E. coli: RuvC protein cleaves Holliday junctions at resolution hotspots in vitro. Cell, 79, 853-864.
31. Shah, R., Cosstick, R. and West, S.C. (1997) The RuvC dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts. EMBO J., 16, 1464-1472.
32. Sharples, G.J., Benson, F.E., Illing, G.T. and Lloyd, R.G. (1990) Molecular, and functional analysis of the ruv region of Escherichia coli K-12 reveals three genes involved in DNA repair and recombination. Mol. Gen. Genet., 221, 219-226.
33. Shida, T., Iwasaki, H., Saito, A., Kyogoku, Y. and Shinagawa, H. (1996) Analysis of substrate specificity of the RuvC Holliday junction resolvase with synthetic Holliday junctions. J. Biol. Chem., 271, 26105-26109.
34. Shinagawa, H. and Iwasaki, H. (1996) Processing the Holliday junction in homologous recombination. Trends Biochem. Sci., 21, 107-111.
35. Story, R.M., Bishop, D.K., Kleckner, N. and Steitz, T.A. (1993) Structural relationship of bacterial RecA proteins to recombination proteins from bacteriophage T4 and yeast. Science, 259, 1892-1896.
36. Sung, P. (1994) Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast Rad51 protein. Science, 265, 1241-1243.
37. Tsaneva, I.R., Illing, G.T., Lloyd, R.G. and West, S.C. (1992a) Purification and properties of the RuvA and RuvB proteins of Escherichia coli. Mol. Gen. Genet., 235, 1-10.
38. Tsaneva, I.R., Müller, B. and West, S.C. (1992b) ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E.coli. Cell, 69, 1171-1180.
39. Tullius, T.D. and Dombroski, B.A. (1986) Hydroxyl radical footprinting: High resolution information about DNA-protein contacts and application to lambda repressor and Cro protein. Proc. Natl Acad. Sci. USA, 83, 5469-5473.
40. West, S.C. (1997) Processing of recombination intermediates by the RuvABC proteins. Annu. Rev. Genet., 31, 213-244.
41. Whitby, M.C., Bolt, E.L., Chan, S.N. and Lloyd, R.G. (1996) Interactions between RuvA and RuvC at Holliday junctions: inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex. J. Mol. Biol., 264, 878-890.
42. Yu, X., West, S.C. and Egelman, E.H. (1997) Structure and subunit composition of the RuvAB-Holliday junction complex. J. Mol. Biol., 266, 217-222.