Structure and subunit composition of the RuvAB-Holliday junction complex

Journal of Molecular Biology

Volumn 266, Issue 2, 1997, Pages 217-222

  Yu, Xiong ^a   West, Stephen C ^b   Egelman, Edward H ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Electron microscopy; Holliday junctions; Image analysis; RuvA; RuvB

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; HELICASE;

ARTICLE; BACTERIOPHAGE T7; DNA REPAIR; ELECTRON MICROSCOPY; ESCHERICHIA COLI; HOLLIDAY JUNCTION; HYDROLYSIS; IMAGE ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0031581811     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0799     Document Type: Editorial

References (31)

1. Adams D. E., West S. C. Bypass of DNA heterologies during RuvAB-mediated three- and four-strand branch migration. J. Mol. Biol. 263:1996;582-596.
2. Benson F. E., Illing G. T., Sharples G. J., Lloyd R. G. Nucleotide sequencing of the ruv region of E. coli K-12 reveals a LexA regulated operon encoding two genes. Nucl. Acids. Res. 16:1988;1541-1550.
3. Dean F. B., Borowiec J. A., Eki T., Hurwitz J. The Simian Virus 40 T antigen double hexamer assembles around the DNA at the replication origin. J. Biol. Chem. 267:1992;14129-14137.
4. Egelman E. H. Homomorphous hexameric helicases: tales from the ring cycle. Structure. 4:1996;759-762.
5. Egelman E. H., Yu X., Wild R., Hingorani M. M., Patel S. S. Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases. Proc. Natl Acad. Sci. USA. 92:1995;3869-3873.
6. Frank J., Shimkin B., Dowse H. SPIDER: A modular software system for electron image processing. Ultramicroscopy. 6:1981;343-358.
7. Hingorani M. M., Patel S. S. Interactions of bacteriophage T7 DNA primase/helicase protein with single-stranded and double-stranded DNAs. Biochemistry. 32:1993;12478-12487.
8. Iwasaki H., Takahagi M., Nakata A., Shinagawa H. Escherichia coli RuvA and RuvB proteins specifically interact with Holliday junctions and promote branch migration. Genes Dev. 6:1992;2214-2220.
9. Iype L. E., Wood E. A., Inman R. B., Cox M. M. RuvA and RuvB proteins facilitate the bypass of heterologous DNA insertions during RecA protein-mediated DNA strand exchange. J. Biol. Chem. 269:1994;24967-24978.
10. Iype L. E., Inman R. B., Cox M. M. Blocked RecA protein-mediated DNA strand exchange reactions are reversed by the RuvA and RuvB proteins. J. Biol. Chem. 270:1995;19473-19480.
11. Lloyd R. G., Sharples G. J. Processing of recombination intermediates by the RecG and RuvAB proteins of Escherichia coli. Nucl. Acids. Res. 21:1993;1719-1725.
12. Matic I., Rayssiguier C., Radman M. Interspecies gene exchange in bacteria: the role of SOS and mismatch repair systems in evolution of species. Cell. 80:1995;507-515.
13. Matson S. W., Tabor S., Richardson C. C. The gene 4 protein of bacteriophage T7. Characterization of helicase activity. J. Biol. Chem. 258:1983;14017-14024.
14. Mitchell A. H., West S. C. Hexameric rings of Escherichia coli RuvB protein. Cooperative assembly, processivity and ATPase activity. J. Mol. Biol. 243:1994;208-215.
15. Müller B., Tsaneva I. R., West S. C. Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins: II. Interaction of RuvB with DNA. J. Biol. Chem. 268:1993;17185-17189.
16. Parsons C. A., West S. C. Formation of a RuvAB-Holliday junction complex in vitro. J. Mol. Biol. 232:1993;397-405.
17. Parsons C. A., Tsaneva I., Lloyd R. G., West S. C. Interaction of Escherichia coli RuvA and RuvB proteins with synthetic Holliday junctions. Proc. Natl Acad. Sci. USA. 89:1992;5452-5456.
18. Parsons C. A., Stasiak A., Bennet R. J., West S. C. Structure of a multisubunit complex that promotes DNA branch migration. Nature. 374:1995a;375-378.
19. Parsons C. A., Stasiak A., West S. C. The E. coli RuvAB proteins branch migrate Holliday junctions through heterologous DNA sequences in a reaction facilitated by SSB. EMBO J. 14:1995b;5736-5744.
20. Penczek P., Radermacher M., Frank J. Three-dimensional reconstruction of single particles embedded in ice. Ultramicroscopy. 40:1992;33-53.
21. Rafferty J. B., Sedelnikova S. E., Hargreaves D., Artymiuk P. J., Baker P. J., Sharples G. J., Mahdi A. A., Lloyd R. G., Rice D. W. Crystal structure of the DNA recombination protein RuvA and a model for its binding to the Holliday junction. Science. 274:1996;415-421.
22. Salinas F., Kodadek T. Phage T4 homologous strand exchange: a DNA helicase, not the strand transferase, drives polar branch migration. Cell. 82:1995;111-119.
23. Shiba T., Iwasaki H., Nakata A., Shinagawa H. SOS-inducible DNA repair proteins, RuvA and RuvB, of Escherichia coli: functional interactions between RuvA and RuvB for ATP hydrolysis and renaturation of the cruciform structure in supercoiled DNA. Proc. Natl Acad. Sci. USA. 88:1991;8445-8449.
24. Shinagawa H., Makino K., Amemura M., Kimura S., Iwasaki H., Nakata A. Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination. J. Bacteriol. 170:1988;4322-4329.
25. Stasiak A., Tsaneva I. R., West S. C., Benson C. J. B., Yu X., Egelman E. H. The Escherichia coli RuvB branch migration protein forms double hexameric rings around DNA. Proc. Natl Acad. Sci. USA. 91:1994;7618-7622.
26. Tsaneva I. R., Illing G. T., Lloyd R. G., West S. C. Purification and properties of the RuvA and RuvB proteins of Escherichia coli. Mol. Gen. Genet. 235:1992a;1-10.
27. Tsaneva I. R., Muller B., West S. C. ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli. Cell. 69:1992b;1171-1180.
28. Tsaneva I. R., Muller B., West S. C. The RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro. Proc. Natl Acad. Sci. USA. 90:1993;1315-1319.
29. Wall J. S., Hainfeld J. F. Mass mapping with the scanning transmission electron microscope. Annu. Rev. Biophys. Biophys. Chem. 15:1986;355-376.
30. West S. C. DNA helicases: new breeds of translocating motors and molecular pumps. Cell. 86:1996;177-180.
31. Yu X., Hingorani M. M., Patel S. S., Egelman E. H. DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicase. Nature Struct. Biol. 3:1996;740-743.