메뉴 건너뛰기




Volumn 34, Issue 2, 1996, Pages 165-175

Drug metabolic enzymes in developmental toxicology

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; ISOENZYME;

EID: 26844447583     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0187     Document Type: Conference Paper
Times cited : (67)

References (70)
  • 2
    • 0025886840 scopus 로고
    • The herpes simplex virus type-1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter
    • Al-Shawi, R., Burke, J., Wallace, H., Jones, C., Harrison, S., Buxton, D., Maley, S., Chandley, A., and Bishop, J. O. (1991). The herpes simplex virus type-1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter. Mol. Cell. Biol. 11, 4207-4216.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4207-4216
    • Al-Shawi, R.1    Burke, J.2    Wallace, H.3    Jones, C.4    Harrison, S.5    Buxton, D.6    Maley, S.7    Chandley, A.8    Bishop, J.O.9
  • 3
    • 0022261987 scopus 로고
    • Fetal mouse susceptibility to transplacental lung and liver carcinogenesis by 3-methylcholanthrene: Positive correlation with responsiveness to inducers of aromatic hydrocarbon metabolism
    • Anderson, L. M., Jones, A. B., Riggs, C. W., and Ohshima, M. (1985). Fetal mouse susceptibility to transplacental lung and liver carcinogenesis by 3-methylcholanthrene: Positive correlation with responsiveness to inducers of aromatic hydrocarbon metabolism. Carcinogenesis, 6, 1389-1393.
    • (1985) Carcinogenesis , vol.6 , pp. 1389-1393
    • Anderson, L.M.1    Jones, A.B.2    Riggs, C.W.3    Ohshima, M.4
  • 4
    • 0024351374 scopus 로고
    • Metabolism of transplacental carcinogens
    • (N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, Eds.) IARC Scientific Publications No. 96
    • Anderson, L. M., Jones, A. B., Miller, M. S., and Chauhan, D. P. (1989). Metabolism of transplacental carcinogens. In Transplacental and Multigeneration Carcinogenesis (N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, Eds.), pp. 155-188. IARC Scientific Publications No. 96.
    • (1989) Transplacental and Multigeneration Carcinogenesis , pp. 155-188
    • Anderson, L.M.1    Jones, A.B.2    Miller, M.S.3    Chauhan, D.P.4
  • 6
    • 0021358883 scopus 로고
    • Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines
    • Bradley, A., Evans, M., Kaufman, M. H., and Robertson, E. (1984). Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines. Nature 309, 255-256.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 7
    • 0028135079 scopus 로고
    • Altering mice by homologous recombination using embryonic stem cells
    • Bronson, S. K., and Smithies, O. (1994). Altering mice by homologous recombination using embryonic stem cells. J. Biol. Chem. 269, 27155-27158.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27155-27158
    • Bronson, S.K.1    Smithies, O.2
  • 8
    • 0023221116 scopus 로고
    • Gestational risk factors for Wilms' tumor: Results of a case-control study
    • Bunin, G. R., Kramer, S., Marrero, O., and Meadows, A. T. (1987). Gestational risk factors for Wilms' tumor: Results of a case-control study. Cancer Res. 47, 2972-2977.
    • (1987) Cancer Res. , vol.47 , pp. 2972-2977
    • Bunin, G.R.1    Kramer, S.2    Marrero, O.3    Meadows, A.T.4
  • 9
    • 0024564718 scopus 로고
    • The new mouse genetics: Altering the genome by gene targeting
    • Capecchi, M. R. (1987). The new mouse genetics: Altering the genome by gene targeting. Trends Genet. 5, 70-76.
    • (1987) Trends Genet. , vol.5 , pp. 70-76
    • Capecchi, M.R.1
  • 10
    • 0030051333 scopus 로고    scopus 로고
    • Expression, induction and catalytic activity of the ethanol-inducible cytochrome P450 (CYP2E1) in human fetal liver
    • Carpenter, S. P., Lasker, J. M., and Raucy, J. L. (1996). Expression, induction and catalytic activity of the ethanol-inducible cytochrome P450 (CYP2E1) in human fetal liver. Mol. Pharmacol. 49, 260-268.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 260-268
    • Carpenter, S.P.1    Lasker, J.M.2    Raucy, J.L.3
  • 11
    • 0028897720 scopus 로고
    • Tetracycline-reversible silencing of eukaryotic promoters
    • Deuschle, U., Meyer, W. K. H., and Thiesen, H. J. (1995). Tetracycline-reversible silencing of eukaryotic promoters. Mol. Cell. Biol. 15, 1907-1914.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1907-1914
    • Deuschle, U.1    Meyer, W.K.H.2    Thiesen, H.J.3
  • 13
    • 0028938747 scopus 로고
    • Conditional transformation of a pancreatic β-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene
    • Efrat, S., Fusco-DeMane, D., Lemberg, H., Al Emran, O., and Wang, X. (1995). Conditional transformation of a pancreatic β-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene. Proc. Natl. Acad. Sci. USA 92, 3576-3580.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3576-3580
    • Efrat, S.1    Fusco-Demane, D.2    Lemberg, H.3    Al Emran, O.4    Wang, X.5
  • 14
    • 0024546914 scopus 로고
    • Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450
    • Ekstrom, G., and Ingelman-Sundberg, M. (1989). Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450. Biochem. Pharmacol. 38, 1813-1819.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1813-1819
    • Ekstrom, G.1    Ingelman-Sundberg, M.2
  • 16
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M., and Bujard, H. (1992). Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 17
    • 0027501690 scopus 로고
    • Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements
    • Gossen, M., Bonin, A. L., and Bujard, H. (1993). Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biol. Sci. 18, 471-475.
    • (1993) Trends Biol. Sci. , vol.18 , pp. 471-475
    • Gossen, M.1    Bonin, A.L.2    Bujard, H.3
  • 18
  • 19
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu, H., Zou, Y. R., and Rajewsky, K. (1993). Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73, 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 20
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting
    • Gu, H., Marth, J. D., Orban, P. C., Mossmann, H., and Rajewsky, K. (1994). Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting. Science 265, 103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 21
    • 0026742987 scopus 로고
    • Transplacental exposure to tobacco smoke in human-adduct formation in placenta and umbilical cord blood vessels
    • Hansen, C., Sørensen, L. D., Asmussen, I., and Autrup, H. (1992). Transplacental exposure to tobacco smoke in human-adduct formation in placenta and umbilical cord blood vessels. Teratogen. Carcinogen. Mutagen. 12, 51-60.
    • (1992) Teratogen. Carcinogen. Mutagen. , vol.12 , pp. 51-60
    • Hansen, C.1    Sørensen, L.D.2    Asmussen, I.3    Autrup, H.4
  • 22
    • 0028030082 scopus 로고
    • Mechanisms underlying expression of Tn10-encoded tetracycline resistance
    • Hillen, W., and Berens, C. (1994). Mechanisms underlying expression of Tn10-encoded tetracycline resistance. Annu. Rev. Microbiol. 48, 345-404.
    • (1994) Annu. Rev. Microbiol. , vol.48 , pp. 345-404
    • Hillen, W.1    Berens, C.2
  • 23
    • 0024400489 scopus 로고
    • Occurrence and inducibility of cytochrome P450IIIA in maternal and fetal rats during prenatal development
    • Hulla, J. E., and Juchau, M. R. (1989). Occurrence and inducibility of cytochrome P450IIIA in maternal and fetal rats during prenatal development. Biochemistry 28, 4871-4880.
    • (1989) Biochemistry , vol.28 , pp. 4871-4880
    • Hulla, J.E.1    Juchau, M.R.2
  • 24
    • 0026031285 scopus 로고
    • Prenatal exposure to parents' smoking and childhood cancer
    • John, E. M., Savitz, D. A., and Sandler, D. P. (1991). Prenatal exposure to parents' smoking and childhood cancer. Am. J. Epid. 133, 123-132.
    • (1991) Am. J. Epid. , vol.133 , pp. 123-132
    • John, E.M.1    Savitz, D.A.2    Sandler, D.P.3
  • 25
    • 0015821371 scopus 로고
    • Recognition of the fetal alcohol syndrome in early infancy
    • Jones, K. L., and Smith, D. W. (1973). Recognition of the fetal alcohol syndrome in early infancy. Lancet II, 999-1001.
    • (1973) Lancet , vol.2 , pp. 999-1001
    • Jones, K.L.1    Smith, D.W.2
  • 26
    • 0024573809 scopus 로고
    • Bioactivation in chemical teratogenesis
    • Juchau, M. R. (1989). Bioactivation in chemical teratogenesis. Annu. Rev. Pharmacol. Toxicol. 29, 165-187.
    • (1989) Annu. Rev. Pharmacol. Toxicol. , vol.29 , pp. 165-187
    • Juchau, M.R.1
  • 27
    • 0026590729 scopus 로고
    • Xenobiotic biotransformation/bioactivation in organogenesis-stage conceptal tissues: Implications for embryotoxicity and teratogenesis
    • Juchau, M. R., Lee, Q. P., and Fantel, A. G. (1992). Xenobiotic biotransformation/bioactivation in organogenesis-stage conceptal tissues: Implications for embryotoxicity and teratogenesis. Drug Metab. Rev. 24, 195-238.
    • (1992) Drug Metab. Rev. , vol.24 , pp. 195-238
    • Juchau, M.R.1    Lee, Q.P.2    Fantel, A.G.3
  • 28
    • 0029901865 scopus 로고    scopus 로고
    • Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus
    • Kitamura, M. (1996). Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus. Proc. Natl. Acad. Sci. USA 93, 7387-7391.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7387-7391
    • Kitamura, M.1
  • 29
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P4502E1
    • Koop, D. R. (1992). Oxidative and reductive metabolism by cytochrome P4502E1. FASEB J. 6, 724-730.
    • (1992) FASEB J. , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 30
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kühn, R., Schwenk, F., Aguet, M., and Rajewsky, K. (1995). Inducible gene targeting in mice. Science 269, 1427-1429.
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kühn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 31
    • 0026066337 scopus 로고
    • Human embryonic cytochrome P450s: Phenoxazone ethers as probes for expression of functional isoforms during organogenesis
    • Lee, Q. P., Fantel, A. G., and Juchau, M. R. (1991). Human embryonic cytochrome P450s: Phenoxazone ethers as probes for expression of functional isoforms during organogenesis. Biochem. Pharmacol. 42, 2377-2386.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 2377-2386
    • Lee, Q.P.1    Fantel, A.G.2    Juchau, M.R.3
  • 32
    • 0029954239 scopus 로고    scopus 로고
    • Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
    • Li, Z. W., Stark, G., Götz, J., Rülicke, T., and Müller, U. (1996). Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. Proc. Natl. Acad. Sci. USA 93, 6158-6162.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6158-6162
    • Li, Z.W.1    Stark, G.2    Götz, J.3    Rülicke, T.4    Müller, U.5
  • 34
    • 0026531911 scopus 로고
    • Determinants of polycyclic aromatic hydrocarbonDNA adducts in human placenta
    • Manchester, D. K., Bowman, E. D., Parker, N. B., Caporaso, N. E., and Weston, A. (1992). Determinants of polycyclic aromatic hydrocarbonDNA adducts in human placenta. Cancer Res. 52, 1499-1503.
    • (1992) Cancer Res. , vol.52 , pp. 1499-1503
    • Manchester, D.K.1    Bowman, E.D.2    Parker, N.B.3    Caporaso, N.E.4    Weston, A.5
  • 35
    • 0024558427 scopus 로고
    • Differential induction of fetal mouse liver and lung cytochromes P-450 by β-naphthoflavone and 3-methylcholanthrene
    • Miller, M. S., Jones, A. B., Chauhan, D. P., Park, S. S., and Anderson, L. M. (1989). Differential induction of fetal mouse liver and lung cytochromes P-450 by β-naphthoflavone and 3-methylcholanthrene. Carcinogenesis 10, 875-883.
    • (1989) Carcinogenesis , vol.10 , pp. 875-883
    • Miller, M.S.1    Jones, A.B.2    Chauhan, D.P.3    Park, S.S.4    Anderson, L.M.5
  • 36
    • 0025194293 scopus 로고
    • The formation of 3-methylcholanthrene-initiated lung tumors correlates with induction of cytochrome CYPIA1 by the carcinogen in fetal but not adult mice
    • Miller, M. S., Jones, A. B., and Anderson, L. M. (1990a). The formation of 3-methylcholanthrene-initiated lung tumors correlates with induction of cytochrome CYPIA1 by the carcinogen in fetal but not adult mice. Toxicol. Appl. Pharmacol. 104, 235-245.
    • (1990) Toxicol. Appl. Pharmacol. , vol.104 , pp. 235-245
    • Miller, M.S.1    Jones, A.B.2    Anderson, L.M.3
  • 37
    • 0025173292 scopus 로고
    • Role of the maternal environment in determining susceptibility to transplacentally induced chemical carcinogenesis in mouse fetuses
    • Miller, M. S., Jones, A. B., Chauhan, D. P., and Anderson, L. M. (1990b). Role of the maternal environment in determining susceptibility to transplacentally induced chemical carcinogenesis in mouse fetuses. Carcinogenesis 11, 1979-1984.
    • (1990) Carcinogenesis , vol.11 , pp. 1979-1984
    • Miller, M.S.1    Jones, A.B.2    Chauhan, D.P.3    Anderson, L.M.4
  • 38
    • 0028064637 scopus 로고
    • Transplacental lung carcinogenesis: A pharmacogenetic mouse model for the modulatory role of cytochrome P450 1A1 on lung cancer initiation
    • Miller, M. S. (1994). Transplacental lung carcinogenesis: A pharmacogenetic mouse model for the modulatory role of cytochrome P450 1A1 on lung cancer initiation. Res. Chem. Toxicol. 7, 471-481.
    • (1994) Res. Chem. Toxicol. , vol.7 , pp. 471-481
    • Miller, M.S.1
  • 39
    • 0029670543 scopus 로고    scopus 로고
    • Position effects and genetic disease
    • Milot, E., Fraser, P., and Grosveld, F. (1996). Position effects and genetic disease. Trends Genet. 12, 123-126.
    • (1996) Trends Genet. , vol.12 , pp. 123-126
    • Milot, E.1    Fraser, P.2    Grosveld, F.3
  • 40
    • 0025785811 scopus 로고
    • Mutations of ras genes distinguish a subset of non-small cell lung cancer cell lines from small-cell lung cancer cell lines
    • Mitsudomi, T., Viallet, J., Mulshine, J. L., Linnoila, R. I., Minna, J. D., and Gazdar, A. F. (1991). Mutations of ras genes distinguish a subset of non-small cell lung cancer cell lines from small-cell lung cancer cell lines. Oncogene, 6, 1353-1362.
    • (1991) Oncogene , vol.6 , pp. 1353-1362
    • Mitsudomi, T.1    Viallet, J.2    Mulshine, J.L.3    Linnoila, R.I.4    Minna, J.D.5    Gazdar, A.F.6
  • 42
    • 0028223294 scopus 로고
    • Cytochrome P450-dependent biotransformation of 2-acetylaminofluorene in cell-free preparations of human embryonic hepatic, adrenal, renal, pulmonary and cardiac tissues
    • Namkung, M. J., Yang, H. L., and Juchau, M. R. (1994). Cytochrome P450-dependent biotransformation of 2-acetylaminofluorene in cell-free preparations of human embryonic hepatic, adrenal, renal, pulmonary and cardiac tissues. Drug Metab. Dispos. 22, 331-337.
    • (1994) Drug Metab. Dispos. , vol.22 , pp. 331-337
    • Namkung, M.J.1    Yang, H.L.2    Juchau, M.R.3
  • 43
    • 0024829409 scopus 로고
    • The Ah locus: Genetic differences in toxicity, cancer, mutation, and birth defects
    • Nebert, D. W. (1989). The Ah locus: Genetic differences in toxicity, cancer, mutation, and birth defects. Crit. Rev. Toxicol. 20, 153-174.
    • (1989) Crit. Rev. Toxicol. , vol.20 , pp. 153-174
    • Nebert, D.W.1
  • 44
    • 0028040226 scopus 로고
    • Drug-metabolizing enzymes in ligand-modulated transcription
    • Nebert, D. W. (1994). Drug-metabolizing enzymes in ligand-modulated transcription. Biochem. Pharmacol. 47, 25-37.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 25-37
    • Nebert, D.W.1
  • 45
    • 0027922810 scopus 로고
    • Role of the ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer and in signal transduction
    • Nebert, D. W., Puga, A., and Vasiliou, V. (1993). Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer and in signal transduction. Ann. N. Y. Acad. Sci. 685, 624-640.
    • (1993) Ann. N. Y. Acad. Sci. , vol.685 , pp. 624-640
    • Nebert, D.W.1    Puga, A.2    Vasiliou, V.3
  • 47
    • 0029993449 scopus 로고    scopus 로고
    • Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4
    • Olson, E. N., Arnold, H. H., Rigby, P. W. J., and Wold, B. J. (1996). Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 85, 1-4.
    • (1996) Cell , vol.85 , pp. 1-4
    • Olson, E.N.1    Arnold, H.H.2    Rigby, P.W.J.3    Wold, B.J.4
  • 48
    • 0026764280 scopus 로고
    • Tissue-and site-specific dna recombination in transgenic mice
    • Orban, P. C., Chui, D., and Marth, J. D. (1992). Tissue-and site-specific DNA recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89, 6861-6865.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6861-6865
    • Orban, P.C.1    Chui, D.2    Marth, J.D.3
  • 49
    • 0022763969 scopus 로고
    • The reaction of a 3-methylcholanthrene diol epoxide with DNA in relation to the binding of 3-methylcholanthrene to the DNA of mammalian cells
    • Osborne, M. R., Brookes, P., Lee, H., and Harvey, R. G. (1986). The reaction of a 3-methylcholanthrene diol epoxide with DNA in relation to the binding of 3-methylcholanthrene to the DNA of mammalian cells. Carcinogenesis 7, 1345-1350.
    • (1986) Carcinogenesis , vol.7 , pp. 1345-1350
    • Osborne, M.R.1    Brookes, P.2    Lee, H.3    Harvey, R.G.4
  • 50
    • 0001917440 scopus 로고
    • Fetoplacental biochemistry - Xenobiotic metabolism and pharmacokinetics
    • (K. Hemminki, M. Sorsa, and H. Vainio, Eds.) Hemisphere, Washington, DC
    • Pelkonen, O. (1985). Fetoplacental biochemistry - xenobiotic metabolism and pharmacokinetics. In Occupational Hazards and Reproduction (K. Hemminki, M. Sorsa, and H. Vainio, Eds.) pp. 113-126. Hemisphere, Washington, DC.
    • (1985) Occupational Hazards and Reproduction , pp. 113-126
    • Pelkonen, O.1
  • 51
  • 52
    • 0015215861 scopus 로고
    • Metabolism of ethanol and acetaldehyde in perfused human fetal liver
    • Pikkarainen, P. H. (1971). Metabolism of ethanol and acetaldehyde in perfused human fetal liver. Life Sci. 10, 1359-1364.
    • (1971) Life Sci. , vol.10 , pp. 1359-1364
    • Pikkarainen, P.H.1
  • 54
    • 0024401849 scopus 로고
    • Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2
    • Raucy, J. L., Lasker, J. M., Lieber, C. S., and Black, M. (1989). Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. Arch. Biochem. Biophys. 271, 270-283.
    • (1989) Arch. Biochem. Biophys. , vol.271 , pp. 270-283
    • Raucy, J.L.1    Lasker, J.M.2    Lieber, C.S.3    Black, M.4
  • 55
    • 0027177328 scopus 로고
    • The expression of xenobiotic-metabolizing cytochromes P450 in fetal tissues
    • Raucy, J. L., and Carpenter, S. J. (1993). The expression of xenobiotic-metabolizing cytochromes P450 in fetal tissues. J. Pharmacol. Toxicol. Methods 29, 121-128.
    • (1993) J. Pharmacol. Toxicol. Methods , vol.29 , pp. 121-128
    • Raucy, J.L.1    Carpenter, S.J.2
  • 56
    • 0030015421 scopus 로고    scopus 로고
    • Characterization of a murine Ahr null allele: Involvement of the Ah receptor in hepatic growth and development
    • Schmidt, J. V., Su, G. H. T., Reddy, J. K., Simon, M. C., and Bradfield, C. A. (1996). Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. USA 93, 6731-6736.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6731-6736
    • Schmidt, J.V.1    Su, G.H.T.2    Reddy, J.K.3    Simon, M.C.4    Bradfield, C.A.5
  • 57
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk, F., Baron, U., and Rajewsky, K. (1995). A Cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080-5081.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3
  • 58
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking the EGF receptor
    • Sibilia, M., and Wagner, E. F. (1995). Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269, 234-238.
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.F.2
  • 59
    • 0029883166 scopus 로고    scopus 로고
    • Creating conditional mutations in mammals
    • Spencer, D. M. (1996). Creating conditional mutations in mammals. Trends Genet. 12, 181-187.
    • (1996) Trends Genet. , vol.12 , pp. 181-187
    • Spencer, D.M.1
  • 60
    • 0022575842 scopus 로고
    • Maternal smoking during pregnancy and risk of childhood cancer
    • Stjernfeldt, M., Berglund K., Lindsten, J., and Ludvigsson, J. (1986). Maternal smoking during pregnancy and risk of childhood cancer. Lancet 1, 1350-1352.
    • (1986) Lancet , vol.1 , pp. 1350-1352
    • Stjernfeldt, M.1    Berglund, K.2    Lindsten, J.3    Ludvigsson, J.4
  • 61
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas, K. R., and Capecchi, M. R. (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 63
    • 0029119145 scopus 로고
    • Cre-mediated site-specific translocation between nonhomologous mouse chromosomes
    • Van Deursen, J., Fornerod, M., van Rees, B., and Grosveld, G. (1995). Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. Proc. Natl. Acad. Sci. USA 92, 7376-7380.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7376-7380
    • Van Deursen, J.1    Fornerod, M.2    Van Rees, B.3    Grosveld, G.4
  • 64
    • 0029549959 scopus 로고
    • Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine Phase II [Ah] battery gene expression
    • Vasiliou, V., Puga, A., Chang, C. Y., Tabor, M. W., and Nebert, D. W. (1995). Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine Phase II [Ah] battery gene expression. Biochem. Pharmacol. 50, 2057-2068.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 2057-2068
    • Vasiliou, V.1    Puga, A.2    Chang, C.Y.3    Tabor, M.W.4    Nebert, D.W.5
  • 65
    • 0029987470 scopus 로고    scopus 로고
    • Induction of activating gene mutations at the Ki-ras locus following transplacental exposure of mice to 3-methylcholanthrene
    • Wessner, L. L., Fan, M., Schaeffer, D. O., McEntee, M. F., and Miller, M. S. (1996). Induction of activating gene mutations at the Ki-ras locus following transplacental exposure of mice to 3-methylcholanthrene. Carcinogenesis 7, 1519-1526.
    • (1996) Carcinogenesis , vol.7 , pp. 1519-1526
    • Wessner, L.L.1    Fan, M.2    Schaeffer, D.O.3    McEntee, M.F.4    Miller, M.S.5
  • 66
    • 0023180791 scopus 로고
    • Fetal alcohol-induced brain damage and the problem of determining temporal vulnerability
    • West, J. R. (1987). Fetal alcohol-induced brain damage and the problem of determining temporal vulnerability: A review. Alcohol Drug Res. 7, 423-441.
    • (1987) Alcohol Drug Res. , vol.7 , pp. 423-441
    • West, J.R.1
  • 68
    • 0025167020 scopus 로고
    • Cytochrome P450IIE1 roles of nitrosamine metabolism and mechanisms of regulation
    • Yang, C. S., Yoo, J. S. H., Ishizaki, H., and Hong, J. (1990). Cytochrome P450IIE1 roles of nitrosamine metabolism and mechanisms of regulation. Drug Metab. Rev. 22, 147-153.
    • (1990) Drug Metab. Rev. , vol.22 , pp. 147-153
    • Yang, C.S.1    Yoo, J.S.H.2    Ishizaki, H.3    Hong, J.4
  • 69
    • 0028149573 scopus 로고
    • Functional P4503A isoforms in human embryonic tissues: Expression during organogenesis
    • Yang, H. L., Lee, Q. P., Rettie, A. E., and Juchau, M. R. (1994). Functional P4503A isoforms in human embryonic tissues: Expression during organogenesis. Mol. Pharmacol. 46, 922-929.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 922-929
    • Yang, H.L.1    Lee, Q.P.2    Rettie, A.E.3    Juchau, M.R.4
  • 70
    • 0028916165 scopus 로고
    • Expression of functional cytochrome P4501A1 in human embryonic hepatic tissues during organogenesis
    • Yang, H. L., Namkung, M. J., and Juchau, M. R. (1995). Expression of functional cytochrome P4501A1 in human embryonic hepatic tissues during organogenesis. Biochem. Pharmacol. 49, 717-726.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 717-726
    • Yang, H.L.1    Namkung, M.J.2    Juchau, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.