Increased rate of HIV-1 entry and its cytopathic effect in CD4+/CXCR4+ T cells expressing relatively high levels of CD26

Experimental Cell Research

Volumn 241, Issue 2, 1998, Pages 352-362

  Callebaut, Christian ^a   Jacotot, Etienne ^a   Blanco, Julià ^a   Krust, Bernard ^a   Hovanessian, Ara G ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Apoptosis; CD26; DPP IV; Entry; HIV

Indexed keywords

CD4 ANTIGEN; DIPEPTIDYL PEPTIDASE IV;

APOPTOSIS; ARTICLE; COMPLEX FORMATION; CYTOPATHOGENIC EFFECT; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TARGET CELL; VIRUS INFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032526993     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4063     Document Type: Article

References (70)

1. Fleischer B. CD26: A surface protease involved in T-cell activation. Immunol. Today. 15:1994;180-184.
2. Morimoto C., Lord C. I., Zhang C., Duke-Cohan J. S., Letvin N. L., Schlossman S. F. Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;9960-9964.
3. Morimoto C., Torimoto Y., Levinson G., Rudd C. E., Schrieber M., Dang N. H., Letvin N., Schlossman S. F. IF7, A novel cell surface molecule involved in helper function of CD4 cells. J. Immunol. 143:1989;3430-3439.
4. Hafler D. A., Chofflon M., Benjamin D., Dang N. H., Breitmeyer J. Mechanisms of immune memory. T-cell activation and CD3 phosphorylation correlates with Ta1 (CDw26) expression. J. Immunol. 142:1989;2590-2596.
5. Dang N. H., Hafler D. A., Schlossman S. F., Breitmeyer J. B. FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation. Cell. Immunol. 125:1990;42-57.
6. De Pasquale A., Ginaldi L., Limoncelli P., Quaglino D. Dipteptidyl amino peptidase IV cytochemistry in circulating lymphocytes from HIV-1-seropositive subjects. Acta Haemat. 81:1989;19-21.
7. Valle-Blazquez M., Madueno J. A., Gonzalez R., Jurado R., Bachovchin W. W., Pena J., Munoz E. Selective decrease of CD26 expression in T cells from HIV-1 infected individuals. J. Immunol. 149:1992;3073-3077.
8. Vanham G., Kestens L., De Meester I., Vingerhoets J., Penne G., Vanhoof G., Scharpé S., Heyligen H., Bosmans E., Ceuppens J. L., Gigase P. Decreased expression of the memory marker CD26 on both CD4+ and CD8+ T lymphocytes of HIV-infected subjects. J. AIDS. 6:1993;749-757.
9. Gougeon M. L., Lecoeur H., Callebaut C., Jacotot E., Dulioust A., Roué R., Montagnier L., Hovanessian A. G. Selective loss of CD4+/CD26+ T cell subset during HIV infection. Res. Immunol. 147:1996;5-8.
10. Lane H. C., Depper J. M., Greene W. C., Whalen G., Waldmann T. A., Fauci A. S. Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. New Engl. J. Med. 313:1985;79-84.
11. Schmitz T., Underwood R., Khiroya R., Bachovchin W. W., Huber B. T. Potentiation of the immune response in HIV-1+ individuals. J. Clin. Invest. 97:1996;1545-1549.
12. Bour S., Geleziunas R., Wainberg M. A. The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection. Microbiol. Rev. 59:1995;63-93.
13. Moore J. P., Jameson B. A., Weiss R. A., Sattentau Q. J. The HIV-cell fusion reaction. Viral Fusion Mechanisms. 1993;. p. 233-289.
14. D'Souza M. P., Harden V. A. Chemokines and HIV-1 second receptors. Nature Med. 2:1996;1293-1300.
15. Feng Y., Broder C. C., Kennedy P. E., Berger E. A. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane G protein-coupled receptor. Science. 272:1996;872-876.
16. Deng H., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M., Di Marzio P., Marmon S., Sutton R. E., Hill C. M., Davis C. B., Peiper S. C., Schall T. J., Littman D. R., Landau N. R. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 381:1996;661-666.
17. Dragic T., Litwin V., Allaway G. P., Martin S. R., Huang Y., Nagashima K. A., Cayanan C., Maddon P. J., Koup R. A., Moore J. P., Paxton W. A. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature. 381:1996;667-673.
18. Choe H., Farzan M., Sun Y., Sullivan N., Rollins B., Ponath P. D., Wu L., Mackay C. R., La rosa G., Newman W., Gerard N., Gerard C., Sodroski J. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 85:1996;1135-1148.
19. Doranz B. J., Rucker J., Yi Y., Smyth R. J., Samson M., Peiper S. C., Parmentier M., Collman R. G., Doms R. W. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3 and CKR-2b as fusion cofactors. Cell. 85:1996;1149-1158.
20. Callebaut C., Jacotot E., Krust B., Guichard G., Blanco J., Svab J., Muller S., Briand J. P., Hovanessian A. G. Pseudopeptides TASP inhibitors of HIV infection block viral entry by binding to a 95 kDa cell surface protein. J. Biol. Chem. 272:1997;7159-7166.
21. +. Science. 262:1993;2045-2050.
22. Broder C., Nussbaum O., Gutheil W. G., Bachovchin W. W., Berger E. A. CD26 antigen and HIV fusion. (Technical Comments) Science. 264:1994;1156-1159.
23. Camerini D., Planelles V., Chen I. S. Y. CD26 antigen and HIV fusion. Science. 264:1994;1160-1161.
24. Patience C., McKnight A., Clapham P. R., Boyd M. T., Weiss R. A., Schulz T. F. CD26 antigen and HIV fusion. Science. 264:1994;1159-1160.
25. Alizon M., Dragic T. CD26 antigen and HIV fusion. Science. 264:1994;1161-1162.
26. Callebaut C., Jacotot E., Krust B., Hovanessian A. G. CD26 Antigen and HIV Fusion. Science. 264:1994;1156-1165.
27. Lazaro I., Naniche D., Signoret N., Bernard A.-M., Marguet D., Klatzmann D., Dragic T., Alizon M., Sattentau Q. Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26. J. Virol. 68:1994;6535-6546.
28. Watkins B. A., Crowley R. W., Davis A. E., Louie A. T., Reitz M. S. Jr. Expression of CD26 does not correlate with the replication of macrophage-tropic strains of HIV-1 in T-cell lines. Virology. 224:1996;276-280.
29. Wang Y.-H., Davies A. H., Jones I. M. Expression and purification of glutathione S-transferease-tagged HIV-1 gp120: No evidence of an interaction with CD26. Virology. 208:1995;142-146.
30. Oravecz T., Roderiquez G., Koffi J., Wang J., Ditto M., Bou-Habib D. C., Lusso P., Norcross M. A. CD26 expression correlates with entry, replication and cytopathicity of monocytotropic HIV-1 strains in a T-cell line. Nature Med. 1:1995;919-926.
31. Callebaut C., Hovanessian A. G. CD26 and HIV infection. Res. Virol. 147:1996;67-69.
32. Chin L. T., Duenas M., Levi M., Hinkula J., Wahren B., Borrebaeck C. A. K. Molecular characterization of a human anti-HIV 1 monoclonal antibody revealed a CD26-related motif in CDR2. Immunol. Lett. 44:1995;25-30.
33. Callebaut C., Jacotot E., Marié I., Blank U., Robert N., Krust B., Hovanessian A. The role of CD26 in HIV infection: Viral entry and its cytopathic effect. Retrovirus of Human AIDS and Related Diseases. 1994;. p. 141-149.
34. +. Virology. 223:1996;318-330.
35. Valenzuela A., Blanco J., Callebaut C., Jacotot E., Lluis C., Hovanessian A. G., Franco R. Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope gp120 and viral particles. J. Immunol. 158:1997;3721-3729.
36. Morimoto C., Schlossman S. F. CD26, a key costimulatory molecule on CD4 memory cells. Immunologist. 2:1994;4-7.
37. Southern P. J., Berg P. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1:1982;327-341.
38. Takebe Y., Seiki M., Fujisawa J., Hoy P., Yokota K., Arai K., Yoshida M., Arai N. SR alpha promoter: An efficient an versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8:1988;466-472.
39. Callebaut C., Jacotot E., Guichard G., Krust B., Rey-Cuille M. A., Cointe D., Benkirane N., Blanco J., Muller S., Briand J. P., Hovanessian A. G. Inhibition of HIV infection by pseudopeptides blocking viral envelope glycoprotein-mediated membrane fusion and cell death. Virology. 218:1996;181-192.
40. Jacotot E., Krust B., Callebaut C., Laurent-Crawford A. G., Blanco J., Hovanessian A. G. HIV-1 envelope glycoproteins mediated apoptosis is regulated by CD4 dependent and independent mechanisms. Apoptosis. 2:1997;47-60.
41. Laurent-Crawford A. G., Krust B., Rivière Y., Desgranges C., Muller S., Kieny M. P., Dauguet C., Hovanessian A. G. Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells. AIDS Res. Human Retroviruses. 9:1993;761-773.
42. Dang N. H., Torimoto Y., Schlossman S. F., Morimoto C. Human CD4 helper T cell activation: functional involvement of two distinct collagen receptors, 1F7 and VLA integrin family. J. Exp. Med. 172:1990;649-652.
43. Trono D. Partial reverse transcripts in virions from human immunodeficiency and murine leukemia viruses. J. Virol. 66:1992;4893-4900.
44. Jacotot E., Callebaut C., Blanco J., Krust B., Neubert K., Barth A., Hovanessian A. G. Dipeptidyl peptidase IV-b: a novel form of cell-surface expressed protein with dipeptidyl peptidase IV activity. Eur. J. Biochem. 239:1996a;248-258.
45. Blanco J., Marié I., Callebaut C., Jacotot E., Krust B., Hovanessian A. G. Specific-Binding of adenosine deaminase but not HIV-1 transactivator protein Tat of human CD26. Exp. Cell Res. 225:1996;102-111.
46. Tachibana K., Nakajima T., Sato A., Igarashi K., Shida H., Iizasa H., Yoshida N., Yoshie O., Kishimoto T., Nagasawa T. CXCR4/fusin is not a species-specific barrier in murine cells for HIV-1 entry. J. Exp. Med. 185:1997;1865-1870.
47. Torimoto Y., Dang N. H., Vivier E., Tanaka T., Schlossman S. F., Morimoto C. Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes. J. Immunol. 147:1991;2514-2517.
48. Dukes C. S., Yu Y., Rivadeneira E. D., Sauls D. L., Liao H.-X., Haynes B. F., Weinberg J. B. Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism. J. Virol. 69:1995;4000-4005.
49. Pantaleo G., Butini L., Graziosi C., Poli G., Schnittman S. M., Greenhouse J. J., Gallin J. I., Fauci A. S. Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission. J. Exp. Med. 173:1991;511-514.
50. Sato A. I., Balamuth F. B., Ugen K. E., Williams W. V., Weiner D. B. Identification of CD7 glycoprotein as an accessory molecule in HIV-1 mediated syncytium formation and cell free infection. J. Immunol. 152:1994;5142-5152.
51. Duke-Cohan J. S., Morimoto C., Rocker J. A., Schlossman S. F. Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells. J. Immunol. 156:1996;1714-1721.
52. Tanaka T., Kameoka J., Yaron A., Schlossman S. F., Morimoto C. The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity. Proc. Natl. Acad. Sci. USA. 90:1993;4586-4590.
53. Oravecz T., Pall M., Roderiquez G., Gorrell M. D., Ditto M., Nguyen N. Y., Boykins R., Unsworth E., Norcross M. A. Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage. J. Exp. Med. 186:1997;1865-1872.
54. Crump M. P., Gong J.-H., Loetscher P., Rajarathnam K., Amara A., Arenzana-Seisdedos F., Virelizier J.-L., Baggiolini M., Sykes B. D., Clark-Lewis I. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J. 16:1997;6696-7007.
55. Bleul C. C., Wu L., Hoxie J. A., Springer T. A., Mackay C. R. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc. Natl. Acad. Sci. USA. 94:1997;1925-1930.
56. Trkola A., Dragic T., Arthos J., Binley J. M., Olson W. C., Allaway G. P., Cheng-Mayer C., Robinson J., Maddon P. J., Moore J. P. CD4-dependent antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature. 384:1996;184-187.
57. Wu L., Gerard N. P., Wyatt R., Choe H., Parolin C., Ruffing N., Borsetti A., Cardoso A. A., Desjardin E., Newman W., Gerard C., Sodroski J. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 384:1996;179-183.
58. Lapham C. K., Ouyang J., Chandrasekhar B., Nguyen N. Y., Dimitrov D. S., Golding H. Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science. 274:1996;602-605.
59. Ugolini S., Moulard M., Mondor I., Barois N., Demandolx D., Hoxie J., Brelot A., Alizon M., Davoust J., Sattentau Q. J. HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4. J. Immunol. 159:1997;3000-3008.
60. Dianzani U., Bragardo M., Buonfiglio D., Redoglia V., Funaro A., Portoles P., Rojo J., Malavasi F., Pileri A. Modulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120. Eur. J. Immunol. 25:1995;1306.
61. Feito M. J., Bragardo M., Buonfiglio D., Bonissoni S., Bottarel F., Malavasi F., Dianzani U. gp120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules. Internat. Immunol. 9:1997;1141-1147.
62. Dang N. H., Torimoto Y., Sugita K., Daley J. F., Schow P., Prado C., Schlossman S. F., Morimoto C. Cell surface modulation of CD26 by anti-1F7 monoclonal antibody. Analysis of surface expression and human T cell activation. J. Immunol. 145:1990;3963-3971.
63. Dang N. H., Torimoto Y., Shimamura K., Tanaka T., Daley J. F., Schlossman S. F., Morimoto C. 1F7 (CD26): A marker of thymic maturation involved in the differential regulation of the CD3 and CD2 pathways of human thymocyte activation. J. Immunol. 147:1991;2825-2832.
64. Werner A., Mattern T., Ulmer A.-J., Flad H. D., Kurth R., Baier M. CD26 is not required for infection of the lymphoma cell line C8166 with HIV-1. AIDS. 8:1994;1348-1349.
65. Schnittman S. M., Lane H. C., Greenhouse J., Justement J. S., Baseler M., Fauci A. S. Preferential infection of CD4 memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc. Natl. Acad. Sci. USA. 87:1990;6058-6062.
66. van Noesel C. J., Gruters R. A., Terpstra F. G., Schellekens P. T., van Lier R. A., Miedema F. Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men. J. Clin. Invest. 86:1990;293-299.
67. Chou C.-C., Gudeman V., O'Rourke S., Isacescu V., Detels R., Williams G. J., Mitsuyasu R. T., Giorgi J. V. Phenotypically defined memory CD4+ cells are not selectively decreased in chronic HIV disease. J. AIDS. 7:1994;665-675.
68. ++. Nature Med. 3:1997;533-540.
69. Chun T.-W., Carruth L., Finzi D., Shen X., DiGuiseppe J. A., Taylor H., Hermankova M., Chadwick K., Margolick J., Quinn T. C., Kuo Y.-H., Brookmeyer R., Zeiger M. A., Barditch-Crovo P., Siliciano R. F. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature. 387:1997;183-188.
70. Helbert M. R., Walter J., L'Age J., Beverley P. C. L. HIV infection of CD45RA+ and CD45RO+ CD4+ T cells. Clin. Exp. Immunol. 107:1997;300-305.