-
1
-
-
85030286494
-
RO45-2081 (TNFR55-IgGI) in the treatment of patients' with severe sepsis/septic shock: Preliminary results
-
Deaville, France
-
Abraham E, Glauser MP, Gelmont D, et al. RO45-2081 (TNFR55-IgGI) in the treatment of patients' with severe sepsis/septic shock: preliminary results [abstract]. Proceedings of Second Annual Thematic Meeting on Sepsis; Deaville, France, 1995
-
(1995)
Proceedings of Second Annual Thematic Meeting on Sepsis
-
-
Abraham, E.1
Glauser, M.P.2
Gelmont, D.3
-
2
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor-n in patients with sepsis syndrome: A ramdomized, controlled, double-blind multicenter clinical trial
-
Abraham E, Wunderink R, Silverman H, et al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor-n in patients with sepsis syndrome: a ramdomized, controlled, double-blind multicenter clinical trial. JAMA 1995; 27:5:934-41
-
(1995)
JAMA
, vol.27
, Issue.5
, pp. 934-941
-
-
Abraham, E.1
Wunderink, R.2
Silverman, H.3
-
3
-
-
0024493666
-
Animal models that simulate circulatory shock in Immans: Fact or fancy?
-
Adams HR. Animal models that simulate circulatory shock in Immans: fact or fancy? Prog Clin Biol Res 1989; 299:241-42
-
(1989)
Prog Clin Biol Res
, vol.299
, pp. 241-242
-
-
Adams, H.R.1
-
5
-
-
0027194217
-
Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits
-
Aiura K, Gelfand JA, Burke JF, et al. Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits. Infect Immun 1993; 61:3342-50
-
(1993)
Infect Immun
, vol.61
, pp. 3342-3350
-
-
Aiura, K.1
Gelfand, J.A.2
Burke, J.F.3
-
6
-
-
0000635911
-
Definitions for sepsis and organ failure and guideline's for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee. Definitions for sepsis and organ failure and guideline's for the use of innovative therapies in sepsis. Crit Care Med 1992; 20:864
-
(1992)
Crit Care Med
, vol.20
, pp. 864
-
-
-
7
-
-
0027986554
-
Raudomized phase I/II trial of a macrophage-specific immunomodulator (PGG-glucan) in high-risk surgical patients
-
Babineau TJ, Marcello P, Swails W, et al. Raudomized phase I/II trial of a macrophage-specific immunomodulator (PGG-glucan) in high-risk surgical patients. Ann Surg 1994; 220:601-09
-
(1994)
Ann Surg
, vol.220
, pp. 601-609
-
-
Babineau, T.J.1
Marcello, P.2
Swails, W.3
-
8
-
-
0026079224
-
Divergent efficacy of antibody to tumor necrosis factor-alpha in intravascular and peritonitis models of sepsis
-
Bagby GJ, Plessala KJ, Wilson LA, et al. Divergent efficacy of antibody to tumor necrosis factor-alpha in intravascular and peritonitis models of sepsis. J Infect Dis 1991; 163:83-8
-
(1991)
J Infect Dis
, vol.163
, pp. 83-88
-
-
Bagby, G.J.1
Plessala, K.J.2
Wilson, L.A.3
-
9
-
-
0028596919
-
Effects of N-acetyleysteine in endotoxic shock
-
Bakker J, Zhang H. Depierreux M, et al. Effects of N-acetyleysteine in endotoxic shock. J Crit Care 1994; 9:236-43
-
(1994)
J Crit Care
, vol.9
, pp. 236-243
-
-
Bakker, J.1
Zhang, H.2
Depierreux, M.3
-
11
-
-
0029095166
-
The serine/threonine phosphatase inhibitor, calyeulin A inhibits and dissociates macrophage responses to lipopolysaccharide
-
Barber SA, Perera PY, McNally R, et al. The serine/threonine phosphatase inhibitor, calyeulin A inhibits and dissociates macrophage responses to lipopolysaccharide. J Immunol 1995; 155:1401-10
-
(1995)
J Immunol
, vol.155
, pp. 1401-1410
-
-
Barber, S.A.1
Perera, P.Y.2
McNally, R.3
-
12
-
-
0029931873
-
Regulation of gene expression and nitric oxide production in murine macrophages by the serine/threonine phosphatase inhibitor okadaic acid
-
Barber SA, Salkowski CA, Fultz MJ, et al. Regulation of gene expression and nitric oxide production in murine macrophages by the serine/threonine phosphatase inhibitor okadaic acid. J Endotoxin Res 1996; 3:19-27
-
(1996)
J Endotoxin Res
, vol.3
, pp. 19-27
-
-
Barber, S.A.1
Salkowski, C.A.2
Fultz, M.J.3
-
13
-
-
0028034853
-
A prospective comparison of two multiple organ dysfunction failure/scoring systems for prediction of mortality in critical surgical illness
-
Barrie PS, Hydol J, Fischer E. A prospective comparison of two multiple organ dysfunction failure/scoring systems for prediction of mortality in critical surgical illness. J Trauma 1994; 37:660-66
-
(1994)
J Trauma
, vol.37
, pp. 660-666
-
-
Barrie, P.S.1
Hydol, J.2
Fischer, E.3
-
14
-
-
0028850810
-
An overview of mortality risk prediction in sepsis
-
Barriere SL, Lowry SF. An overview of mortality risk prediction in sepsis. Crit Care Med 1995; 23:376-93
-
(1995)
Crit Care Med
, vol.23
, pp. 376-393
-
-
Barriere, S.L.1
Lowry, S.F.2
-
15
-
-
0021843019
-
Prevention of Gram negative shock and death in surgical patients by antibody to endotoxin core glycolipid
-
Baumgartner J-D, McCutchan JA, Melle GV, et al. Prevention of Gram negative shock and death in surgical patients by antibody to endotoxin core glycolipid. Lancet 1985; 13:59
-
(1985)
Lancet
, vol.13
, pp. 59
-
-
Baumgartner, J.-D.1
McCutchan, J.A.2
Melle, G.V.3
-
16
-
-
0029092928
-
Sepsis trials: Intersection of investigation, regulation, funding and practice
-
Bernard GR. Sepsis trials: intersection of investigation, regulation, funding and practice. Am J Respir Crit Care Med 1995; 152:4-10
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 4-10
-
-
Bernard, G.R.1
-
17
-
-
0026361304
-
Experimental design for drug development: A Bayesian approach
-
Berry DA. Experimental design for drug development: a Bayesian approach (review). J Biopharm Stat 1991; 1:81-101
-
(1991)
J Biopharm Stat
, vol.1
, pp. 81-101
-
-
Berry, D.A.1
-
18
-
-
0027444774
-
Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord red blood cells
-
Bhat NM, Bieber MM, Chapman CJ, et al. Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord red blood cells. J Immunol 1993; 151:5011
-
(1993)
J Immunol
, vol.151
, pp. 5011
-
-
Bhat, N.M.1
Bieber, M.M.2
Chapman, C.J.3
-
19
-
-
0028963589
-
Informed consent in emergency research: Consensus statement from the coalition conference of acute resuscitation and critical care researchers
-
Biros MH, Lewis RJ, Olson CM, et al. Informed consent in emergency research: consensus statement from the coalition conference of acute resuscitation and critical care researchers. JAMA 1995; 273:1283-87
-
(1995)
JAMA
, vol.273
, pp. 1283-1287
-
-
Biros, M.H.1
Lewis, R.J.2
Olson, C.M.3
-
20
-
-
0023946308
-
Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections of mice via activation of PMN function
-
Blanchard DK, Djen JY, Klein TW, et al. Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections of mice via activation of PMN function. J Leukocyte Biol 1988; 43:429-35
-
(1988)
J Leukocyte Biol
, vol.43
, pp. 429-435
-
-
Blanchard, D.K.1
Djen, J.Y.2
Klein, T.W.3
-
21
-
-
0023252009
-
A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
-
Bone RC, Fisher CJ, Clemmer TP, et al. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 1987; 317:653
-
(1987)
N Engl J Med
, vol.317
, pp. 653
-
-
Bone, R.C.1
Fisher, C.J.2
Clemmer, T.P.3
-
22
-
-
0027215981
-
Compartmentalization of the acute cytokine response in humans after intravenous endotoxin administration
-
Boujoukos AJ, Martich GD, Supinski E, et al. Compartmentalization of the acute cytokine response in humans after intravenous endotoxin administration. J Appl Physiol 1993; 74: 3027-33
-
(1993)
J Appl Physiol
, vol.74
, pp. 3027-3033
-
-
Boujoukos, A.J.1
Martich, G.D.2
Supinski, E.3
-
23
-
-
0022853319
-
The involvement of iron in lipid peroxidation
-
Braughler JM, Duncan LA, Chase HL. The involvement of iron in lipid peroxidation. J Biol Chem 1986; 261:10282-89
-
(1986)
J Biol Chem
, vol.261
, pp. 10282-10289
-
-
Braughler, J.M.1
Duncan, L.A.2
Chase, H.L.3
-
25
-
-
0026609630
-
2+ pump of the plasma membrane
-
2+ pump of the plasma membrane. J Biol Chem 1992; 267:2115-18
-
(1992)
J Biol Chem
, vol.267
, pp. 2115-2118
-
-
Carafoli, E.1
-
26
-
-
0027731546
-
Plasma cytokines and endotoxin levels correlate with survival in patients with the sepsis syndrome
-
Casey LC, Balk RA, Bone RC. Plasma cytokines and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993; 119:771-78
-
(1993)
Ann Intern Med
, vol.119
, pp. 771-778
-
-
Casey, L.C.1
Balk, R.A.2
Bone, R.C.3
-
27
-
-
0028831997
-
Calcium signaling
-
Clapham DE. Calcium signaling. Cell 1995; 80:259-68
-
(1995)
Cell
, vol.80
, pp. 259-268
-
-
Clapham, D.E.1
-
28
-
-
15144341521
-
TNF and anti-TNF in sepsis: Experimental basis of evaluation of new therapeutic approaches to sepsis
-
Vincent J-L, ed. Berlin: Springer Verlag
-
Cohen J. TNF and anti-TNF in sepsis: experimental basis of evaluation of new therapeutic approaches to sepsis. In: Vincent J-L, ed. Update in intensive care and emergency medicine No. 16. Berlin: Springer Verlag, 1992; 308-14
-
(1992)
Update in Intensive Care and Emergency Medicine No. 16
, vol.16
, pp. 308-314
-
-
Cohen, J.1
-
29
-
-
85030287507
-
INTERSEPT: An international multicenter placebo controlled trial of monoclonal antibody to human TNF-alpha in patients with sepsis
-
in press
-
Cohen J, Carlet J, and the INTERSEPT Study Group. INTERSEPT: an international multicenter placebo controlled trial of monoclonal antibody to human TNF-alpha in patients with sepsis. Crit Care Med (in press)
-
Crit Care Med
-
-
Cohen, J.1
Carlet, J.2
-
30
-
-
0027281370
-
Choice of bacteria in animal models of sepsis
-
Cross AS, Opal SM, Sadoff JD, et al. Choice of bacteria in animal models of sepsis. Infect Immun 1993; 61:2741-44
-
(1993)
Infect Immun
, vol.61
, pp. 2741-2744
-
-
Cross, A.S.1
Opal, S.M.2
Sadoff, J.D.3
-
31
-
-
0027458448
-
The efficacy of combination immunotherapy in experimental Pseudomonas sepsis
-
Cross AS, Opal SM, Palardy JE, et al. The efficacy of combination immunotherapy in experimental Pseudomonas sepsis. J Infect Dis 1993; 167:112-18
-
(1993)
J Infect Dis
, vol.167
, pp. 112-118
-
-
Cross, A.S.1
Opal, S.M.2
Palardy, J.E.3
-
32
-
-
0027057262
-
Role of protein kinase C activity in tumor necrosis factor-alpha gene expression: Involvement at the transcriptioual level
-
Chung IY, Kwon J, Benveniste EN. Role of protein kinase C activity in tumor necrosis factor-alpha gene expression: involvement at the transcriptioual level. J Immunol 1992; 149: 3894-3902
-
(1992)
J Immunol
, vol.149
, pp. 3894-3902
-
-
Chung, I.Y.1
Kwon, J.2
Benveniste, E.N.3
-
33
-
-
0028850991
-
Granulocyte colony-stimulating factor-role and relationship in infectious diseases
-
Dale DC, Liles WC, Summer WR, et al. Granulocyte colony-stimulating factor-role and relationship in infectious diseases. J Infect Dis 1995; 172:1061-75
-
(1995)
J Infect Dis
, vol.172
, pp. 1061-1075
-
-
Dale, D.C.1
Liles, W.C.2
Summer, W.R.3
-
35
-
-
0027528798
-
Anticytokine strategies in the treatment of the systemic inflammatory response syndrome
-
Dinarello CA, Gelfand JA, Wolff SM. Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA 1993; 269:1829-35
-
(1993)
JAMA
, vol.269
, pp. 1829-1835
-
-
Dinarello, C.A.1
Gelfand, J.A.2
Wolff, S.M.3
-
36
-
-
0027760823
-
Towards a statistically oriented decision support system for the management of septicemia
-
Dybowski B, Cransden WR, Phillips I. Towards a statistically oriented decision support system for the management of septicemia. Artif Intell Med 1993; 5:489-502
-
(1993)
Artif Intell Med
, vol.5
, pp. 489-502
-
-
Dybowski, B.1
Cransden, W.R.2
Phillips, I.3
-
37
-
-
0023940030
-
Use of a Bayesian statistical model for risk assessment in coronary artery surgery
-
Edwards FH, Albus BA, Zajtchuk R, et al. Use of a Bayesian statistical model for risk assessment in coronary artery surgery. Ann Thorac Surg 1988; 45:437-40
-
(1988)
Ann Thorac Surg
, vol.45
, pp. 437-440
-
-
Edwards, F.H.1
Albus, B.A.2
Zajtchuk, R.3
-
38
-
-
0028059590
-
Why have new effective therapies for sepsis not been developed?
-
Eidelman RA, Sprung CL. Why have new effective therapies for sepsis not been developed? Crit Care Med 1994; 20:1330-34
-
(1994)
Crit Care Med
, vol.20
, pp. 1330-1334
-
-
Eidelman, R.A.1
Sprung, C.L.2
-
40
-
-
0027406403
-
Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis: The CB0006 Sepsis Syndrome Study Group
-
Fisher CJ Jr, Opal SM, Dhainant JF, et al. Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis: the CB0006 Sepsis Syndrome Study Group. Crit Care Med 1993; 21:318-27
-
(1993)
Crit Care Med
, vol.21
, pp. 318-327
-
-
Fisher Jr., C.J.1
Opal, S.M.2
Dhainant, J.F.3
-
41
-
-
0026772736
-
Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia
-
Fisher E, Marano MA, Van Zee KJ, et al. Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia. J Clin Invest 1992; 89:1551-57
-
(1992)
J Clin Invest
, vol.89
, pp. 1551-1557
-
-
Fisher, E.1
Marano, M.A.2
Van Zee, K.J.3
-
42
-
-
0028239555
-
Recombinant human interleukin-1 receptor antagonist in the treatment of patients with the sepsis syndrome - Results from a randomized, double-blind, placebo-controlled trial
-
Fisher JC, Dhainaut JF, Opal SM, et al. Recombinant human interleukin-1 receptor antagonist in the treatment of patients with the sepsis syndrome - results from a randomized, double-blind, placebo-controlled trial. JAMA 1994; 271:1836-43
-
(1994)
JAMA
, vol.271
, pp. 1836-1843
-
-
Fisher, J.C.1
Dhainaut, J.F.2
Opal, S.M.3
-
43
-
-
0028535921
-
Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/Raf-1/MEK/MAPK pathway
-
Geppert TD, Whitehurst CE, Thompson P, et al. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/Raf-1/MEK/MAPK pathway. Mol Med 1994; 1:93-103
-
(1994)
Mol Med
, vol.1
, pp. 93-103
-
-
Geppert, T.D.1
Whitehurst, C.E.2
Thompson, P.3
-
44
-
-
0028997703
-
Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome
-
Goldie AS, Fearon KCH, Ross JA, et al. Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome. JAMA 1995; 247:172-77
-
(1995)
JAMA
, vol.247
, pp. 172-177
-
-
Goldie, A.S.1
Fearon, K.C.H.2
Ross, J.A.3
-
45
-
-
0024203618
-
Hole of xanthine oxidase and granulocytes in ischemia-reperfusion injury
-
Granger DN, Hole of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988; 255:H1269-75
-
(1988)
Am J Physiol
, vol.255
-
-
Granger, D.N.1
-
46
-
-
0025786074
-
Production of interleukin-1 receptor antagonist during experimental endotoxemia
-
Granowitz EV, Santos AA, Poutsiska DD, et al. Production of interleukin-1 receptor antagonist during experimental endotoxemia. Lancet 1991; 338: 1423-24
-
(1991)
Lancet
, vol.338
, pp. 1423-1424
-
-
Granowitz, E.V.1
Santos, A.A.2
Poutsiska, D.D.3
-
47
-
-
0028031497
-
Endotoxemia and bacteremia in patients with sepsis syndrome in the intensive care unit
-
Guidet B, Barakett V, Vassal T, et al. Endotoxemia and bacteremia in patients with sepsis syndrome in the intensive care unit. Chest 1994; 106:1194-1201
-
(1994)
Chest
, vol.106
, pp. 1194-1201
-
-
Guidet, B.1
Barakett, V.2
Vassal, T.3
-
48
-
-
8044229330
-
Recommendations of the Performance Statistics Subgroup
-
Santa Monica, Calif: Rand
-
Hadorn DC, Keeler KB, Rogers WH, et al. Recommendations of the Performance Statistics Subgroup. In: Assessing the performance of mortality prediction models. Santa Monica, Calif: Rand, 1993; 27-9
-
(1993)
Assessing the Performance of Mortality Prediction Models
, pp. 27-29
-
-
Hadorn, D.C.1
Keeler, K.B.2
Rogers, W.H.3
-
49
-
-
0027955127
-
Lipopolysaccharide (LPS)-binding protein accelerates binding of LPS to CD14
-
Hailman E, Lichenstein HS, Wurtel MM, et al. Lipopolysaccharide (LPS)-binding protein accelerates binding of LPS to CD14. J Exp Med 1994; 179:269-77
-
(1994)
J Exp Med
, vol.179
, pp. 269-277
-
-
Hailman, E.1
Lichenstein, H.S.2
Wurtel, M.M.3
-
50
-
-
0028271586
-
Problem solving in artificial neural networks (review)
-
Hampton S. Problem solving in artificial neural networks (review). Prog Neurobiol 1994; 42:229-81
-
(1994)
Prog Neurobiol
, vol.42
, pp. 229-281
-
-
Hampton, S.1
-
51
-
-
0027424403
-
Endotoxin induces rapid protein tyrosine phosphorylation in 70/73 cells expressing CD14
-
Han J, Lee JD, Tobias PS, et al. Endotoxin induces rapid protein tyrosine phosphorylation in 70/73 cells expressing CD14. J Biol Chem 1993; 268:25009-14
-
(1993)
J Biol Chem
, vol.268
, pp. 25009-25014
-
-
Han, J.1
Lee, J.D.2
Tobias, P.S.3
-
52
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs L, et al. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994; 265:808-11
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
-
53
-
-
0025081077
-
Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice
-
Harris HW, Grunfeld C, Feingold KR, et al. Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice. J Clin Invest 1990; 86:696-702
-
(1990)
J Clin Invest
, vol.86
, pp. 696-702
-
-
Harris, H.W.1
Grunfeld, C.2
Feingold, K.R.3
-
54
-
-
0027403323
-
Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death
-
Harris HW, Grunfeld C, Feingold KR, et al. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. J Clin Invest 1993; 91:1028-31
-
(1993)
J Clin Invest
, vol.91
, pp. 1028-1031
-
-
Harris, H.W.1
Grunfeld, C.2
Feingold, K.R.3
-
56
-
-
0027383634
-
L-NMMA increases blood pressure in man
-
Haynes WC, Noon JP, Walker BR, et al. L-NMMA increases blood pressure in man. Lancet 1993; 342:931-32
-
(1993)
Lancet
, vol.342
, pp. 931-932
-
-
Haynes, W.C.1
Noon, J.P.2
Walker, B.R.3
-
58
-
-
0025193590
-
100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha)
-
100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha). Circ Shock 1990; 30:279-92
-
(1990)
Circ Shock
, vol.30
, pp. 279-292
-
-
Hinshaw, L.B.1
Tekamp-Olson, P.2
Chang, A.C.3
-
59
-
-
0030071446
-
Role of endotoxemia in cardiovascular dysfunction and lethality: Virulent and nonvirulent Escherichia coli challenges in a canine model of septic shock
-
Hoffman WD, Danner RL, Ouezado ZMN, et al. Role of endotoxemia in cardiovascular dysfunction and lethality: virulent and nonvirulent Escherichia coli challenges in a canine model of septic shock. Infect Immun 1996; 64:406-12
-
(1996)
Infect Immun
, vol.64
, pp. 406-412
-
-
Hoffman, W.D.1
Danner, R.L.2
Ouezado, Z.M.N.3
-
60
-
-
0027212621
-
A reconstituted apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits
-
Hubsch AP, Powell FS, Lerch PG, et al. A reconstituted apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits. Circ Shock 1993; 40:14-23
-
(1993)
Circ Shock
, vol.40
, pp. 14-23
-
-
Hubsch, A.P.1
Powell, F.S.2
Lerch, P.G.3
-
61
-
-
0027322679
-
Protein kinase C isoenzymes: Divergence in signal transduction
-
Hug H, Sarre TF. Protein kinase C isoenzymes: divergence in signal transduction. Biochem J 1993; 291:329-43
-
(1993)
Biochem J
, vol.291
, pp. 329-343
-
-
Hug, H.1
Sarre, T.F.2
-
62
-
-
0026795102
-
Granulocyte colony-stimulating factor does not enhance endotoxin-induced acute lung injury in guinea pigs
-
Kanazawa M, Ishizaka A, Hasegawa N, et al. Granulocyte colony-stimulating factor does not enhance endotoxin-induced acute lung injury in guinea pigs. Am Rev Respir Dis 1992; 145:1030-35
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1030-1035
-
-
Kanazawa, M.1
Ishizaka, A.2
Hasegawa, N.3
-
63
-
-
0027180430
-
The clinical evaluation of new drugs of sepsis: A prospective study design based on survival analysis
-
Knaus WA, Harrell FE, Fisher CJ, et al. The clinical evaluation of new drugs of sepsis: a prospective study design based on survival analysis. JAMA 1993; 270:1233-41
-
(1993)
JAMA
, vol.270
, pp. 1233-1241
-
-
Knaus, W.A.1
Harrell, F.E.2
Fisher, C.J.3
-
64
-
-
0022256529
-
APACHE II: A severity of disease classification system
-
Knaus WA, Draper KA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med 1985; 13:818-29
-
(1985)
Crit Care Med
, vol.13
, pp. 818-829
-
-
Knaus, W.A.1
Draper, K.A.2
Wagner, D.P.3
-
65
-
-
0028885344
-
The SUPPORT prognostic model: Objective estimate for survival for seriously ill hospitalize adults: study to understand prognoses and preferences for outcomes and risks
-
Knaus WA, Harrell FE, Lynn J, et al. The SUPPORT prognostic model: objective estimate for survival for seriously ill hospitalize adults: study to understand prognoses and preferences for outcomes and risks. Ann Intern Med 1995; 122:191-203
-
(1995)
Ann Intern Med
, vol.122
, pp. 191-203
-
-
Knaus, W.A.1
Harrell, F.E.2
Lynn, J.3
-
66
-
-
0026409568
-
The APACHE III prognostic system risk prediction of hospital mortality for critically ill hospitalized adults
-
Knaus WA, Wagner DP, Draper KA, et al. The APACHE III prognostic system risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991; 100:1619-36
-
(1991)
Chest
, vol.100
, pp. 1619-1636
-
-
Knaus, W.A.1
Wagner, D.P.2
Draper, K.A.3
-
67
-
-
0027180430
-
The clinical evaluation of new drugs for sepsis: A prospective study design based on survival analysis
-
Knaus WA, Harrell FE, Fisher CJ, et al. The clinical evaluation of new drugs for sepsis: a prospective study design based on survival analysis. JAMA 1993; 270:1233-41
-
(1993)
JAMA
, vol.270
, pp. 1233-1241
-
-
Knaus, W.A.1
Harrell, F.E.2
Fisher, C.J.3
-
68
-
-
0028297068
-
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
-
Kolesnick H, Colde DW. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 1994; 77: 325-28
-
(1994)
Cell
, vol.77
, pp. 325-328
-
-
Kolesnick, H.1
Colde, D.W.2
-
69
-
-
0028907812
-
Adenovirus-mediated blockade of tumor necrosis factor in mice protects against endotoxic shock yet impairs pulmonary host defense
-
Kolls JK, Lei D, Nelson S, et al. Adenovirus-mediated blockade of tumor necrosis factor in mice protects against endotoxic shock yet impairs pulmonary host defense. J Infect Dis 1995; 171:570-75
-
(1995)
J Infect Dis
, vol.171
, pp. 570-575
-
-
Kolls, J.K.1
Lei, D.2
Nelson, S.3
-
70
-
-
0026875693
-
Recombinant-human superoxide dismutase attenuates endotoxin-induced lung injury in awake sheep
-
Koyama S, Kobayshi T, Kubo K, et al. Recombinant-human superoxide dismutase attenuates endotoxin-induced lung injury in awake sheep. Am Rev Respir Dis 1992; 145:1404-09
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1404-1409
-
-
Koyama, S.1
Kobayshi, T.2
Kubo, K.3
-
71
-
-
0028865754
-
Thrombin induces activation of p38 MAP kinase in human platelets
-
Kramer RM, Roberts EF, Strifler BA, et al. Thrombin induces activation of p38 MAP kinase in human platelets. J Biol Chem 1995; 270:27395-98
-
(1995)
J Biol Chem
, vol.270
, pp. 27395-27398
-
-
Kramer, R.M.1
Roberts, E.F.2
Strifler, B.A.3
-
72
-
-
7144263457
-
Role of oxygen free radicals in the pathophysiology of sepsis
-
Reinhart K, Eyrich K, Sprung C, eds. Berlin: Springer-Verlag
-
Kretzschmar M. Role of oxygen free radicals in the pathophysiology of sepsis. In: Reinhart K, Eyrich K, Sprung C, eds. Sepsis: current perspectives in pathophysiology and therapy: update in intensive care and emergency medicine No. 18. Berlin: Springer-Verlag, 1994; 122-35
-
(1994)
Sepsis: Current Perspectives in Pathophysiology and Therapy: Update in Intensive Care and Emergency Medicine No. 18
, vol.18
, pp. 122-135
-
-
Kretzschmar, M.1
-
73
-
-
0028961486
-
Customized probability models for early sepsis in adult intensive care patients
-
Le Gall JR, Lemeshow S, Huillard J, et al. Customized probability models for early sepsis in adult intensive care patients. JAMA 1995; 273:644-50
-
(1995)
JAMA
, vol.273
, pp. 644-650
-
-
Le Gall, J.R.1
Lemeshow, S.2
Huillard, J.3
-
74
-
-
0027132478
-
A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study
-
Le Gall JK, Lemeshow S, Saulnier F. A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270:2957-63
-
(1993)
JAMA
, vol.270
, pp. 2957-2963
-
-
Le Gall, J.K.1
Lemeshow, S.2
Saulnier, F.3
-
75
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994; 372:739-46
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
-
76
-
-
0020063002
-
A review of goodness of fit statistics for use in development of logistic regression models
-
Lemeshow S, Hosmer DW Jr. A review of goodness of fit statistics for use in development of logistic regression models. Am J Epidemiol 1982; 115:92-100
-
(1982)
Am J Epidemiol
, vol.115
, pp. 92-100
-
-
Lemeshow, S.1
Hosmer Jr., D.W.2
-
77
-
-
0027422556
-
Mortality probability models (MPM II) based on an international cohort of intensive care unit patients
-
Lemeshow S, Teres D, Klar J. et al. Mortality probability models (MPM II) based on an international cohort of intensive care unit patients. JAMA 1993; 270:2478-86
-
(1993)
JAMA
, vol.270
, pp. 2478-2486
-
-
Lemeshow, S.1
Teres, D.2
Klar, J.3
-
78
-
-
0027136230
-
In vivo protection against endotoxin by plasma high density lipoprotein
-
Levine DM, Parker TS, Donnelly TM, et al. In vivo protection against endotoxin by plasma high density lipoprotein. PNAS 1993: 90:12040-44
-
(1993)
PNAS
, vol.90
, pp. 12040-12044
-
-
Levine, D.M.1
Parker, T.S.2
Donnelly, T.M.3
-
79
-
-
0028836911
-
Adjunctive therapy for septic shock: A review of experimental approaches
-
Lynn WA, Cohen J. Adjunctive therapy for septic shock: a review of experimental approaches. Clin Infect Dis 1995; 20:143
-
(1995)
Clin Infect Dis
, vol.20
, pp. 143
-
-
Lynn, W.A.1
Cohen, J.2
-
80
-
-
0028784689
-
The multiple organ dysfunction (MOD) score, a reliable descriptor of a complex clinical outcome
-
Marshall JC, Cook DJ, Christou NV, et al. The multiple organ dysfunction (MOD) score, a reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23:1638-52
-
(1995)
Crit Care Med
, vol.23
, pp. 1638-1652
-
-
Marshall, J.C.1
Cook, D.J.2
Christou, N.V.3
-
81
-
-
8044222677
-
Shock in Gram negative bacteremia: Predisposing factors, pathophysiology, and treatment
-
Remington JS, Swartz WN, eds. New York: McGraw-Hill.
-
McCabe WR, Olans RN. Shock in Gram negative bacteremia: predisposing factors, pathophysiology, and treatment. In: Remington JS, Swartz WN, eds. Current clinical topics in infectious diseases (vol 2), New York: McGraw-Hill. 1981; 121-50
-
(1981)
Current Clinical Topics in Infectious Diseases
, vol.2
, pp. 121-150
-
-
McCabe, W.R.1
Olans, R.N.2
-
82
-
-
0028557981
-
Treatment of septic shock with a human monoclonal antibody HAIA: A randomized, double-blind, placebo-controlled trial
-
McCloskey RV, Straube RC, Sanders C, et al. Treatment of septic shock with a human monoclonal antibody HAIA: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1994; 121:1-5
-
(1994)
Ann Intern Med
, vol.121
, pp. 1-5
-
-
McCloskey, R.V.1
Straube, R.C.2
Sanders, C.3
-
83
-
-
0027269781
-
2 and antioxidants have opposite effects on activation of NF-n B and AP-1 in intact cells: AP-1 as a secondary antioxidant-responsive factor
-
2 and antioxidants have opposite effects on activation of NF-n B and AP-1 in intact cells: AP-1 as a secondary antioxidant-responsive factor. EMBO J 1993; 12:2005-15
-
(1993)
EMBO J
, vol.12
, pp. 2005-2015
-
-
Meyer, M.1
Schreck, R.2
Baeuerle, P.A.3
-
84
-
-
0027752805
-
The L-arginine nitric oxide pathway
-
Moneada S, Higgs A. The L-arginine nitric oxide pathway. N Engl J Med 1993; 329:2002-12
-
(1993)
N Engl J Med
, vol.329
, pp. 2002-2012
-
-
Moneada, S.1
Higgs, A.2
-
85
-
-
0028204089
-
Role of intracellular calcium in superoxide-induced hepatocyte injury
-
Murata M, Monden M, Umeshita K, et al. Role of intracellular calcium in superoxide-induced hepatocyte injury. Hepatology 1993; 19:1223-28
-
(1993)
Hepatology
, vol.19
, pp. 1223-1228
-
-
Murata, M.1
Monden, M.2
Umeshita, K.3
-
86
-
-
0023736957
-
Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection
-
Nakane A, Minagawa T, Kato K. Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection. Infect Immun 1988; 56:2563-69
-
(1988)
Infect Immun
, vol.56
, pp. 2563-2569
-
-
Nakane, A.1
Minagawa, T.2
Kato, K.3
-
87
-
-
23444446083
-
Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis
-
Natanson C, Hoffman WD, Suffredini AF, et al. Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. Ann Intern Med 1994; 120:771-83
-
(1994)
Ann Intern Med
, vol.120
, pp. 771-783
-
-
Natanson, C.1
Hoffman, W.D.2
Suffredini, A.F.3
-
88
-
-
0024591074
-
Compartmentalization of intra-alveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response
-
Nelson S, Bagby GJ, Bainton BG, et al. Compartmentalization of intra-alveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis 1989; 159:189-94
-
(1989)
J Infect Dis
, vol.159
, pp. 189-194
-
-
Nelson, S.1
Bagby, G.J.2
Bainton, B.G.3
-
89
-
-
85030285907
-
-
News release (fax, July 18, 1994, Synergen: Boulder, Colo)
-
News release (fax, July 18, 1994, Synergen: Boulder, Colo)
-
-
-
-
90
-
-
0029149110
-
Lessons learned from clinical trials of sepsis
-
Opal SM. Lessons learned from clinical trials of sepsis. J Endotoxin Res 1995; 2:221-26
-
(1995)
J Endotoxin Res
, vol.2
, pp. 221-226
-
-
Opal, S.M.1
-
91
-
-
0028343059
-
Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors
-
Novogrodsky A, Vanichkin A, Patya M, et al. Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science 1994; 264:1319-22
-
(1994)
Science
, vol.264
, pp. 1319-1322
-
-
Novogrodsky, A.1
Vanichkin, A.2
Patya, M.3
-
92
-
-
0028233244
-
Fara-amino salicylate blocks the endothelial injury induced by phorbol myristate acetate
-
Overdahl MC, Julian MS, Weisbrode SK, et al. Fara-amino salicylate blocks the endothelial injury induced by phorbol myristate acetate. Am J Respir Crit Care Med 1994; 149: 1640-47
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 1640-1647
-
-
Overdahl, M.C.1
Julian, M.S.2
Weisbrode, S.K.3
-
93
-
-
0028466383
-
Oxygen and the control of gene expression
-
Pahl HL, Baeuerle PA. Oxygen and the control of gene expression. Bioessays 1994; 16:497-502
-
(1994)
Bioessays
, vol.16
, pp. 497-502
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
94
-
-
0027511853
-
The discovery of nitric oxide in the vessel wall: A unifying concept in the pathogenesis of sepsis
-
Palmer RMJ. The discovery of nitric oxide in the vessel wall: a unifying concept in the pathogenesis of sepsis. Arch Surg 1993; 128.396-401
-
(1993)
Arch Surg
, vol.128
, pp. 396-401
-
-
Palmer, R.M.J.1
-
95
-
-
0026346162
-
Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
-
Petros A, Bennett D, Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 1991; 338:1557-58
-
(1991)
Lancet
, vol.338
, pp. 1557-1558
-
-
Petros, A.1
Bennett, D.2
Vallance, P.3
-
96
-
-
0027055454
-
A randomized prospective clinical trial to determine the efficacy of interferon-n in severely injured patients
-
Polk HC, Cheadle WG, Livingston DH, et al. A randomized prospective clinical trial to determine the efficacy of interferon-n in severely injured patients. Am J Surg 1992; 163:191-96
-
(1992)
Am J Surg
, vol.163
, pp. 191-196
-
-
Polk, H.C.1
Cheadle, W.G.2
Livingston, D.H.3
-
97
-
-
0028872983
-
Methylene blue administration in septic shock: A clinical trial
-
Preiser JC, Lejenne P, Roman A, et al. Methylene blue administration in septic shock: a clinical trial. Crit Care Med 1995; 23:259-64
-
(1995)
Crit Care Med
, vol.23
, pp. 259-264
-
-
Preiser, J.C.1
Lejenne, P.2
Roman, A.3
-
98
-
-
0028118814
-
The third component of complement protects against Esceherichia coli endotoxin-induced shock and multiple organ failure
-
Quezado ZMN, Hoffman WD, Winkelstein JA, et al. The third component of complement protects against Esceherichia coli endotoxin-induced shock and multiple organ failure. J Exp Med 1994; 179:569-78
-
(1994)
J Exp Med
, vol.179
, pp. 569-578
-
-
Quezado, Z.M.N.1
Hoffman, W.D.2
Winkelstein, J.A.3
-
99
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 MAP kinase activation by dual phosphorylation on lyrosine and threonine
-
Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 MAP kinase activation by dual phosphorylation on lyrosine and threonine. J Biol Chem 1995; 270:7420-26
-
(1995)
J Biol Chem
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
-
100
-
-
0028893025
-
The natural history of the systemic inflammatory response syndrome (SIRS)
-
Rangel-Fransto MS, Pittet D, Costigan M, et al. The natural history of the systemic inflammatory response syndrome (SIRS). JAMA 1995; 273:117
-
(1995)
JAMA
, vol.273
, pp. 117
-
-
Rangel-Fransto, M.S.1
Pittet, D.2
Costigan, M.3
-
101
-
-
9344246862
-
Assessment of the safety and efficacy of the monoclonal antitumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study
-
Reinhart K. Wiegand-Löhnert C. Grimminger F, et al. Assessment of the safety and efficacy of the monoclonal antitumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo-controlled, dose-ranging study, Crit Care Med 1996; 24:733-42
-
(1996)
Crit Care Med
, vol.24
, pp. 733-742
-
-
Reinhart, K.1
Wiegand-Löhnert, C.2
Grimminger, F.3
-
102
-
-
0027372503
-
Extracellular acidosis ameliorates metabolic-inhibitor-indunced and potentiates oxidant-induced cell death in renal proximal tubules
-
Rodeheaver DP, Schnellman RG. Extracellular acidosis ameliorates metabolic-inhibitor-indunced and potentiates oxidant-induced cell death in renal proximal tubules. J Pharmacol Exp Ther 1993; 265:1355-60
-
(1993)
J Pharmacol Exp Ther
, vol.265
, pp. 1355-1360
-
-
Rodeheaver, D.P.1
Schnellman, R.G.2
-
104
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann RK, Leong SR, Flaggs GW, et al. Structure and function of lipopolysaccharide binding protein. Science 1990; 249:1429-30
-
(1990)
Science
, vol.249
, pp. 1429-1430
-
-
Schumann, R.K.1
Leong, S.R.2
Flaggs, G.W.3
-
105
-
-
0023758683
-
Catalase prevents prostanoid release and lung lipid peroxidation after endotoxemia in sheep
-
Seekamp A, LaLonde C. Zhu DG, et al. Catalase prevents prostanoid release and lung lipid peroxidation after endotoxemia in sheep. J Appl Physiol 1988; 65:1210-16
-
(1988)
J Appl Physiol
, vol.65
, pp. 1210-1216
-
-
Seekamp, A.1
Lalonde, C.2
Zhu, D.G.3
-
106
-
-
0028837050
-
Roundtable conference on clinical trials for the treatment of sepsis
-
Sibbald WJ, Vincent JL. Roundtable conference on clinical trials for the treatment of sepsis. Chest 1995; 107:522-27
-
(1995)
Chest
, vol.107
, pp. 522-527
-
-
Sibbald, W.J.1
Vincent, J.L.2
-
107
-
-
0025091756
-
Withholding and withdrawal of support from the critically ill
-
Smedira NG, Evans BH, Grais LS, et al. Withholding and withdrawal of support from the critically ill. N Engl J Med 1990; 322:309-15
-
(1990)
N Engl J Med
, vol.322
, pp. 309-315
-
-
Smedira, N.G.1
Evans, B.H.2
Grais, L.S.3
-
109
-
-
0028101179
-
Multiple organ dysfunction syndrome: Pathogenesis and approach to therapy
-
St. John BC, Dorinsky PM. Multiple organ dysfunction syndrome: pathogenesis and approach to therapy. Semin Respir Crit Care Med 1994; 15:325-34
-
(1994)
Semin Respir Crit Care Med
, vol.15
, pp. 325-334
-
-
St. John, B.C.1
Dorinsky, P.M.2
-
110
-
-
0022453148
-
Effect of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates
-
Stevens JH, O'Hanley P, Shapiro JM, et al. Effect of anti-C5a antibodies on the adult respiratory distress syndrome in septic primates. J Clin Invest 1986; 77:1812-16
-
(1986)
J Clin Invest
, vol.77
, pp. 1812-1816
-
-
Stevens, J.H.1
O'Hanley, P.2
Shapiro, J.M.3
-
111
-
-
0028343142
-
Current prospects for the treatment of clinical sepsis
-
Suffredini AF. Current prospects for the treatment of clinical sepsis. Crit Care Med 1994; 22:S12
-
(1994)
Crit Care Med
, vol.22
-
-
Suffredini, A.F.1
-
112
-
-
0028221567
-
Granulocyte colony stimulating factor exacerbates acute lung injury induced by intratracheal endotoxin in guinea pigs
-
Terashima T, Kanazawa M, Sayama K, et al. Granulocyte colony stimulating factor exacerbates acute lung injury induced by intratracheal endotoxin in guinea pigs. Am J Respir Crit Care Med 1994; 149:1295-1303
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 1295-1303
-
-
Terashima, T.1
Kanazawa, M.2
Sayama, K.3
-
113
-
-
0025952479
-
The involvement of tumor necrosis factor in immunity to Salmonella infection
-
Tite JP, Dougan C, Chatfield SN. The involvement of tumor necrosis factor in immunity to Salmonella infection. J Immunol 1991; 147:3161-64
-
(1991)
J Immunol
, vol.147
, pp. 3161-3164
-
-
Tite, J.P.1
Dougan, C.2
Chatfield, S.N.3
-
114
-
-
0022462376
-
Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum
-
Tobias P, Soldau K, Ulevitch B. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J Exp Med 1986; 164:777-93
-
(1986)
J Exp Med
, vol.164
, pp. 777-793
-
-
Tobias, P.1
Soldau, K.2
Ulevitch, B.3
-
115
-
-
0027231868
-
Microbial superantigens induce NK-n B in the human monocytic cell line THP-1
-
Trede NS, Castigli E, Gelia HS, et al. Microbial superantigens induce NK-n B in the human monocytic cell line THP-1. J Immunol 1993; 150:5604-10
-
(1993)
J Immunol
, vol.150
, pp. 5604-5610
-
-
Trede, N.S.1
Castigli, E.2
Gelia, H.S.3
-
116
-
-
0027976138
-
Recognition of endotoxin by cells leading to transmembrane signaling
-
Ulevitch HJ, Tobias PS. Recognition of endotoxin by cells leading to transmembrane signaling. Curr Opin Immunol 1994; 6:125-30
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 125-130
-
-
Ulevitch, H.J.1
Tobias, P.S.2
-
117
-
-
0028965644
-
Receptor-dependant mechanisms of cell stimulation by bacterial endotoxin
-
Ulevitch BJ, Tobias PS. Receptor-dependant mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol 1995; 13:437-57
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 437-457
-
-
Ulevitch, B.J.1
Tobias, P.S.2
-
118
-
-
0027549003
-
Role of endogenous nitric oxide in septic shock
-
Vallance P, Moncada S. Role of endogenous nitric oxide in septic shock. New Horizons 1993; 1:77-86
-
(1993)
New Horizons
, vol.1
, pp. 77-86
-
-
Vallance, P.1
Moncada, S.2
-
119
-
-
0029013217
-
Inflammation-induced recombinant protein expression in vivo using promoters from acute phase protein genes
-
Varley AW, Coulthard MG, Meidell RS, et al. Inflammation-induced recombinant protein expression in vivo using promoters from acute phase protein genes. Proc Natl Acad Sci USA 1995; 92:5346
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5346
-
-
Varley, A.W.1
Coulthard, M.G.2
Meidell, R.S.3
-
120
-
-
0025852720
-
A specific receptor antagonist for interleukin-1 prevents Escherichia coli induced shock in rabbits
-
Wakabayashi G, Gelfand JA, Burke JF, et al. A specific receptor antagonist for interleukin-1 prevents Escherichia coli induced shock in rabbits. FASEB J 1991; 5:338-43
-
(1991)
FASEB J
, vol.5
, pp. 338-343
-
-
Wakabayashi, G.1
Gelfand, J.A.2
Burke, J.F.3
-
121
-
-
0008105258
-
The cardiopulmonary effects of 546C88 in human septic shock
-
Watson C, Donaldson J, Grover R, et al. The cardiopulmonary effects of 546C88 in human septic shock. Intensive Care Med 1995; 21:S17
-
(1995)
Intensive Care Med
, vol.21
-
-
Watson, C.1
Donaldson, J.2
Grover, R.3
-
122
-
-
0022973433
-
Macrophage defect and inflammatory cell recruitment dysfunction in Salmonella susceptible C3II/HeJ mice
-
Weinstein DL, Lissner CR, Swanson RN, et al. Macrophage defect and inflammatory cell recruitment dysfunction in Salmonella susceptible C3II/HeJ mice. Cell Immunol 1986; 102:68-77
-
(1986)
Cell Immunol
, vol.102
, pp. 68-77
-
-
Weinstein, D.L.1
Lissner, C.R.2
Swanson, R.N.3
-
123
-
-
0026659881
-
Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinase in macrophages
-
Weinstein SL, Sanghera JS, Lemke K, et al. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinase in macrophages. J Biol Chem 1992; 267:14955-62
-
(1992)
J Biol Chem
, vol.267
, pp. 14955-14962
-
-
Weinstein, S.L.1
Sanghera, J.S.2
Lemke, K.3
-
124
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding proteins
-
Wright SD, Ramos RA, Tobias PS, et al. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding proteins. Science 1990; 249:1431-33
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
-
125
-
-
0029053828
-
CD14 and innate recognition of bacteria
-
Wright SD. CD14 and innate recognition of bacteria. J Immunol 1995; 155:6-8
-
(1995)
J Immunol
, vol.155
, pp. 6-8
-
-
Wright, S.D.1
-
126
-
-
0028935983
-
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein
-
Würfel MM, Hailman E, Wright SD. Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein. J Exp Med 1995; 181:1743-45
-
(1995)
J Exp Med
, vol.181
, pp. 1743-1745
-
-
Würfel, M.M.1
Hailman, E.2
Wright, S.D.3
-
127
-
-
0027982115
-
Lipopolysaccharide (LPS) binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS
-
Wurfel MM, Kunitake ST, Lichenstein HS, et al. Lipopolysaccharide (LPS) binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med 1994, 180:1025-35
-
(1994)
J Exp Med
, vol.180
, pp. 1025-1035
-
-
Wurfel, M.M.1
Kunitake, S.T.2
Lichenstein, H.S.3
-
128
-
-
0026568118
-
Cytokine production after intravenous or peritoneal Gram negative bacterial challenge in mice: Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide
-
Zanetti C, Hemmann D, Gerain J, et al. Cytokine production after intravenous or peritoneal Gram negative bacterial challenge in mice: comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide. J Immunol 1992; 148:1890-97
-
(1992)
J Immunol
, vol.148
, pp. 1890-1897
-
-
Zanetti, C.1
Hemmann, D.2
Gerain, J.3
-
129
-
-
0028820587
-
Rho family GTPases regulate p38 MAP kinase through the downstream mediator Pakl
-
Zhang S, Han J, Sells MA, et al. Rho family GTPases regulate p38 MAP kinase through the downstream mediator Pakl. J Biol Chem 1995; 270:23934-36
-
(1995)
J Biol Chem
, vol.270
, pp. 23934-23936
-
-
Zhang, S.1
Han, J.2
Sells, M.A.3
-
130
-
-
0019906260
-
Treatment of Gram negative bacteremia and shock with human antiserum to a mutant Escherichia coli
-
Ziegler EJ, McCutchan JA, Fierer J, et al. Treatment of Gram negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N Engl J Med 1982; 307:1225-30
-
(1982)
N Engl J Med
, vol.307
, pp. 1225-1230
-
-
Ziegler, E.J.1
McCutchan, J.A.2
Fierer, J.3
|