메뉴 건너뛰기




Volumn 17, Issue 8, 1998, Pages 2334-2341

Erythroid Kruppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the β-globin locus control region

Author keywords

globin; EKLF; Locus control region; Primitive erythropoiesis

Indexed keywords

BETA GLOBIN; ERYTHROID KRUPPEL LIKE FACTOR; GAMMA GLOBIN; DNA BINDING PROTEIN; ERYTHROID KRUPPEL-LIKE FACTOR; GLOBIN; KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR;

EID: 0032521930     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.8.2334     Document Type: Article
Times cited : (71)

References (28)
  • 1
    • 0027377867 scopus 로고
    • Application of lacZ gene fusions to postimplantation development
    • Bonnerot,C. and Nicolas,J.-F. (1993) Application of lacZ gene fusions to postimplantation development. Methods Enzymol., 225, 451-469.
    • (1993) Methods Enzymol. , vol.225 , pp. 451-469
    • Bonnerot, C.1    Nicolas, J.-F.2
  • 2
    • 0029906977 scopus 로고    scopus 로고
    • Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions
    • Chen,X. and Bieker,J.J. (1996) Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions. EMBO J., 15, 5888-5896.
    • (1996) EMBO J. , vol.15 , pp. 5888-5896
    • Chen, X.1    Bieker, J.J.2
  • 4
    • 0029147761 scopus 로고
    • Mouse embryonic hematopoiesis
    • Dzierzak,E. and Medvinsky,A. (1995) Mouse embryonic hematopoiesis. Trends Genet. 11, 359-366.
    • (1995) Trends Genet. , vol.11 , pp. 359-366
    • Dzierzak, E.1    Medvinsky, A.2
  • 5
    • 0030050402 scopus 로고    scopus 로고
    • A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region
    • Ellis.J., Tanun,K.C., Harper,A., Michalovich,D., Yannoutsos,N., Philipsen,S. and Grosveld,F. (1996) A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region. EMBO J., 15, 562-568.
    • (1996) EMBO J. , vol.15 , pp. 562-568
    • Ellis, J.1    Tanun, K.C.2    Harper, A.3    Michalovich, D.4    Yannoutsos, N.5    Philipsen, S.6    Grosveld, F.7
  • 6
    • 0028174097 scopus 로고
    • Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor
    • Feng,W.C., Southwood,C.M. and Bieker,J.J. (1994) Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor. J. Biol. Chem., 269, 1493-1500.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1493-1500
    • Feng, W.C.1    Southwood, C.M.2    Bieker, J.J.3
  • 9
    • 0029954767 scopus 로고
    • Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3
    • Hug,B.A., Wesselschmidt,R.L., Fiering,S., Bender,M.A., Epner,E., Groudine,M. and Ley,T.J. (1906) Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3. Mol. Cell Biol., 16, 2906-2912.
    • (1906) Mol. Cell Biol. , vol.16 , pp. 2906-2912
    • Hug, B.A.1    Wesselschmidt, R.L.2    Fiering, S.3    Bender, M.A.4    Epner, E.5    Groudine, M.6    Ley, T.J.7
  • 10
    • 0022549802 scopus 로고
    • Regulated expression of human A γ-, β-, and hybrid γβ-globin genes in transgenic mice: Manipulation of the developmental expression patterns
    • Kollias,G., Wrighton,N., Hurst,J. and Grosveld,F. (1986) Regulated expression of human A γ-, β-, and hybrid γβ-globin genes in transgenic mice: manipulation of the developmental expression patterns. Cell, 46, 89-94.
    • (1986) Cell , vol.46 , pp. 89-94
    • Kollias, G.1    Wrighton, N.2    Hurst, J.3    Grosveld, F.4
  • 11
    • 0023747623 scopus 로고
    • A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube
    • Kothary,R., Clapoff,S., Brown,A., Campbell,R., Peterson,A. and Rossant,J. (1988) A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature, 335, 435-437.
    • (1988) Nature , vol.335 , pp. 435-437
    • Kothary, R.1    Clapoff, S.2    Brown, A.3    Campbell, R.4    Peterson, A.5    Rossant, J.6
  • 12
    • 0027211845 scopus 로고
    • A novel, erythroid coil-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins
    • Miller,I.J. and Bieker,J.J. (1993) A novel, erythroid coil-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol. Cell. Biol., 13, 2776-2786.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2776-2786
    • Miller, I.J.1    Bieker, J.J.2
  • 13
    • 16044372786 scopus 로고    scopus 로고
    • Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription
    • Milot,E. et al. (1996) Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription. Cell, 87, 105-114.
    • (1996) Cell , vol.87 , pp. 105-114
    • Milot, E.1
  • 14
    • 0026520412 scopus 로고
    • LCR/MEL: A versatile system for high-level expression of heterologous proteins in erythroid cells
    • Needham,M., Gooding,C., Hudson,K., Antoniou,M., Grosveld,F. and Hollis,M. (1992) LCR/MEL: a versatile system for high-level expression of heterologous proteins in erythroid cells. Nucleic Acids Res., 20, 997-1003.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 997-1003
    • Needham, M.1    Gooding, C.2    Hudson, K.3    Antoniou, M.4    Grosveld, F.5    Hollis, M.6
  • 15
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez,B., Michalovich,D., Bygrave,A., Ploemacher,R. and Grosveld,F. (1995) Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature, 375, 316-318.
    • (1995) Nature , vol.375 , pp. 316-318
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 16
    • 0028990264 scopus 로고
    • Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins,A.C., Sharpe,A.H. and Orkin,S.H. (1995) Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature, 375, 318-322.
    • (1995) Nature , vol.375 , pp. 318-322
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 17
    • 0029861514 scopus 로고    scopus 로고
    • Silencing of human fetal globin expression is impaired in the absence of the adult β-globin gene activator protein EKLF
    • Perkins,A.C., Gaensler,K.M. and Orkin,S.H. (1996) Silencing of human fetal globin expression is impaired in the absence of the adult β-globin gene activator protein EKLF. Proc. Natl Acad. Sci. USA, 93, 12267-12271.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 12267-12271
    • Perkins, A.C.1    Gaensler, K.M.2    Orkin, S.H.3
  • 18
    • 0025292742 scopus 로고
    • The β-globin dominant control region: Hypersensitive site 2
    • Philipsen,S., Talbot,D., Fraser,P. and Grosveld,F. (1990) The β-globin dominant control region: hypersensitive site 2. EMBO J., 9, 2159-2167.
    • (1990) EMBO J. , vol.9 , pp. 2159-2167
    • Philipsen, S.1    Talbot, D.2    Fraser, P.3    Grosveld, F.4
  • 19
    • 0027522759 scopus 로고
    • The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the β globin locus control region
    • Philipsen,S., Pruzina,S. and Grosveld,F. (1993) The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the β globin locus control region. EMBO J., 12, 1077-1085.
    • (1993) EMBO J. , vol.12 , pp. 1077-1085
    • Philipsen, S.1    Pruzina, S.2    Grosveld, F.3
  • 21
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
    • Shivdasani,R.A., Fujiwara,Y., McDevitt,M.A. and Orkin,S.H. (1997) A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J., 16, 3965-3973.
    • (1997) EMBO J. , vol.16 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 22
    • 0029658844 scopus 로고    scopus 로고
    • Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny
    • Southwood,C.M., Downs,K.M. and Bieker,J.J. (1996) Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny. Dev. Dyn., 206, 248-259.
    • (1996) Dev. Dyn. , vol.206 , pp. 248-259
    • Southwood, C.M.1    Downs, K.M.2    Bieker, J.J.3
  • 23
    • 0026655863 scopus 로고
    • Developmental regulation of a complete 70-kb human β-globin locus in transgenic mice
    • Strouboulis,J., Dillon,N. and Grosveld,F. (1992) Developmental regulation of a complete 70-kb human β-globin locus in transgenic mice. Genes Dev., 6, 1857-1864.
    • (1992) Genes Dev. , vol.6 , pp. 1857-1864
    • Strouboulis, J.1    Dillon, N.2    Grosveld, F.3
  • 24
    • 0024506821 scopus 로고
    • A dominant control region from the human β-globin locus conferring integration site-independent gene expression
    • Talbot,D., Collis,P., Antoniou,M., Vidal,M., Grosveld,F. and Greaves,D.R. (1989) A dominant control region from the human β-globin locus conferring integration site-independent gene expression. Nature, 338, 352-355.
    • (1989) Nature , vol.338 , pp. 352-355
    • Talbot, D.1    Collis, P.2    Antoniou, M.3    Vidal, M.4    Grosveld, F.5    Greaves, D.R.6
  • 25
    • 0030453172 scopus 로고    scopus 로고
    • The human β-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene
    • Tewari,R., Gillemans,N., Harper,A., Wijgerde,M., Zafarana,G., Drabek,D., Grosveld,F. and Philipsen,S. (1996) The human β-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene. Development, 122, 3991-3999.
    • (1996) Development , vol.122 , pp. 3991-3999
    • Tewari, R.1    Gillemans, N.2    Harper, A.3    Wijgerde, M.4    Zafarana, G.5    Drabek, D.6    Grosveld, F.7    Philipsen, S.8
  • 27
    • 0029051646 scopus 로고
    • Transcription complex stability and chromatin dynamics in vivo
    • Wijgerde,M., Grosveld,F. and Fraser,P. (1995) Transcription complex stability and chromatin dynamics in vivo. Nature, 377, 209-213.
    • (1995) Nature , vol.377 , pp. 209-213
    • Wijgerde, M.1    Grosveld, F.2    Fraser, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.