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Volumn 15, Issue 21, 1996, Pages 5888-5896

Erythroid Kruppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions

Author keywords

EKLF; Erythropoiesis; Proline rich domain; Transcription factor; globin synthesis

Indexed keywords

BETA GLOBIN; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; DNA; ERYTHROID KRUPPEL LIKE FACTOR; ERYTHROID KRUPPEL-LIKE FACTOR; GLOBIN; KRUPPEL LIKE FACTOR; PRIMER DNA; ZINC FINGER PROTEIN;

EID: 0029906977     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00975.x     Document Type: Article
Times cited : (60)

References (52)
  • 1
    • 0344258924 scopus 로고
    • Role of Erythroid Krüppel-like Factor (EKLF) in erythroid-specific transcription
    • Stamatoyannopoulos,G. (ed.), Intercept, Ltd, Andover
    • Bieker, J.J. (1994) Role of Erythroid Krüppel-like Factor (EKLF) in erythroid-specific transcription. In Stamatoyannopoulos,G. (ed.), Molecular Biology of Hemoglobin Switching. Intercept, Ltd, Andover, Vol. 1, pp. 231-241.
    • (1994) Molecular Biology of Hemoglobin Switching , vol.1 , pp. 231-241
    • Bieker, J.J.1
  • 2
    • 0029945923 scopus 로고    scopus 로고
    • Isolation, genomic structure, and expression of human Erythroid Krüppel-like Factor (EKLF)
    • Bieker, J.J. (1996) Isolation, genomic structure, and expression of human Erythroid Krüppel-like Factor (EKLF). DNA Cell Biol., 15, 347-352.
    • (1996) DNA Cell Biol. , vol.15 , pp. 347-352
    • Bieker, J.J.1
  • 3
    • 0028983427 scopus 로고
    • The Erythroid Krüppel-like Factor (EKLF) transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter
    • Bieker, J.J. and Southwood, C.M. (1995) The Erythroid Krüppel-like Factor (EKLF) transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter. Mol. Cell. Biol., 15, 852-860.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 852-860
    • Bieker, J.J.1    Southwood, C.M.2
  • 4
    • 0025806587 scopus 로고
    • Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
    • Binetruy, B., Smeal, T. and Karin, M. (1991) Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature, 351, 122-127.
    • (1991) Nature , vol.351 , pp. 122-127
    • Binetruy, B.1    Smeal, T.2    Karin, M.3
  • 5
    • 0029558513 scopus 로고
    • Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4
    • Bungert, J., Dave, U., Lim, K.C., Lieuw, K.H., Shavit, J.A., Liu, Q. and Engel, J.D. (1995) Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4. Genes Dev., 9, 3083-3096.
    • (1995) Genes Dev. , vol.9 , pp. 3083-3096
    • Bungert, J.1    Dave, U.2    Lim, K.C.3    Lieuw, K.H.4    Shavit, J.A.5    Liu, Q.6    Engel, J.D.7
  • 6
    • 0028949844 scopus 로고
    • Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators
    • Chiang, C.M. and Roeder, R.G. (1995) Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science, 267, 531-536.
    • (1995) Science , vol.267 , pp. 531-536
    • Chiang, C.M.1    Roeder, R.G.2
  • 7
    • 0017868338 scopus 로고
    • Empirical predictions of protein conformation
    • Chou, P.Y. and Fasman, G.D. (1978) Empirical predictions of protein conformation. Annu. Rev. Biochem., 47, 251-256.
    • (1978) Annu. Rev. Biochem. , vol.47 , pp. 251-256
    • Chou, P.Y.1    Fasman, G.D.2
  • 8
    • 0027340097 scopus 로고
    • Interaction between a transcriptional activator and transcription factor IIB in vivo
    • Colgan, J., Wampler, S. and Manley, J.L. (1993) Interaction between a transcriptional activator and transcription factor IIB in vivo. Nature, 362, 549-553.
    • (1993) Nature , vol.362 , pp. 549-553
    • Colgan, J.1    Wampler, S.2    Manley, J.L.3
  • 9
    • 0028936440 scopus 로고
    • Role of Erythroid Krüppel-like Factor (EKLF) in human γ- to β-globin switching
    • Donze, D., Townes, T.M. and Bieker, J.J. (1995) Role of Erythroid Krüppel-like Factor (EKLF) in human γ- to β-globin switching. J. Biol. Chem., 270, 1955-1959.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1955-1959
    • Donze, D.1    Townes, T.M.2    Bieker, J.J.3
  • 10
    • 0027202509 scopus 로고
    • Developmental regulation of human β-globin gene transcription: A switch of loyalties?
    • Engel, J.D. (1993) Developmental regulation of human β-globin gene transcription: a switch of loyalties? Trends Genet., 9, 304-309.
    • (1993) Trends Genet. , vol.9 , pp. 304-309
    • Engel, J.D.1
  • 11
    • 0026599021 scopus 로고
    • Chromatin as an essential part of the transcriptional mechanism
    • Felsenfeld, G. (1992) Chromatin as an essential part of the transcriptional mechanism. Nature, 355, 219-224.
    • (1992) Nature , vol.355 , pp. 219-224
    • Felsenfeld, G.1
  • 12
    • 0028174097 scopus 로고
    • Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor
    • Feng, W.C., Southwood, C.M. and Bieker, J.J. (1994) Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor. J. Biol. Chem., 269, 1493-1500.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1493-1500
    • Feng, W.C.1    Southwood, C.M.2    Bieker, J.J.3
  • 13
    • 0023375317 scopus 로고
    • Metal-dependent folding of a single zinc finger from transcription factor IIIA
    • Frankel, A.D., Berg, J.M. and Pabo, C.O. (1987) Metal-dependent folding of a single zinc finger from transcription factor IIIA. Proc. Natl Acad. Sci. USA, 84, 4841-4845.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 4841-4845
    • Frankel, A.D.1    Berg, J.M.2    Pabo, C.O.3
  • 14
    • 0017873321 scopus 로고
    • Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
    • Garnier, J., Osguthorpe, D.J. and Robson, B. (1978) Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J. Mol. Biol., 120, 97-120.
    • (1978) J. Mol. Biol. , vol.120 , pp. 97-120
    • Garnier, J.1    Osguthorpe, D.J.2    Robson, B.3
  • 15
    • 0023805741 scopus 로고
    • Negative effect of the transcriptional activator GAL4
    • Gill, G. and Ptashne, M. (1988) Negative effect of the transcriptional activator GAL4. Nature, 334, 721-724.
    • (1988) Nature , vol.334 , pp. 721-724
    • Gill, G.1    Ptashne, M.2
  • 16
    • 0024445798 scopus 로고
    • Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
    • Gonzalez, G.A. and Montminy, M.R. (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133, Cell, 59, 675-680.
    • (1989) Cell , vol.59 , pp. 675-680
    • Gonzalez, G.A.1    Montminy, M.R.2
  • 17
    • 0029864417 scopus 로고    scopus 로고
    • Functional interaction of GATA1 with Erythroid Krüppel-like Factor and SP1 at defined erythroid promoters
    • Gregory, R.C., Taxman, D.J., Seshasayee, D., Kensinger, M.H., Bieker, J.J. and Wojchowski, D.M. (1996) Functional interaction of GATA1 with Erythroid Krüppel-like Factor and SP1 at defined erythroid promoters. Blood, 87, 1793-1801.
    • (1996) Blood , vol.87 , pp. 1793-1801
    • Gregory, R.C.1    Taxman, D.J.2    Seshasayee, D.3    Kensinger, M.H.4    Bieker, J.J.5    Wojchowski, D.M.6
  • 18
    • 0027361046 scopus 로고
    • Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
    • Hainaut, P. and Milner, J. (1993) Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res., 53, 4469-4473.
    • (1993) Cancer Res. , vol.53 , pp. 4469-4473
    • Hainaut, P.1    Milner, J.2
  • 19
    • 0011923924 scopus 로고
    • Understanding erythroid differentiation
    • Higgs, D.R. and Wood, W.G. (1993) Understanding erythroid differentiation. Curr. Biol., 3, 548-550.
    • (1993) Curr. Biol. , vol.3 , pp. 548-550
    • Higgs, D.R.1    Wood, W.G.2
  • 20
    • 0028519273 scopus 로고
    • Allosteric activation of latent p53 tetramers
    • Hupp, T.R. and Lane, D.P. (1994) Allosteric activation of latent p53 tetramers. Curr. Biol., 4, 865-875.
    • (1994) Curr. Biol. , vol.4 , pp. 865-875
    • Hupp, T.R.1    Lane, D.P.2
  • 21
    • 0026448672 scopus 로고
    • Regulation of the specific DNA binding function of p53
    • Hupp, T.R., Meek, D.W., Midgley, C.A. and Lane, D.P. (1992) Regulation of the specific DNA binding function of p53. Cell. 71, 875-886.
    • (1992) Cell , vol.71 , pp. 875-886
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4
  • 22
    • 0000127106 scopus 로고
    • Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation
    • Kim, T.K. and Roeder, R.G. (1994) Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation. Proc. Natl Acad. Sci. USA, 91, 4170-4174.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 4170-4174
    • Kim, T.K.1    Roeder, R.G.2
  • 23
    • 0027267480 scopus 로고
    • Loss of erythropoietin reponsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene
    • Kreider, B.L., Orkin, S.H. and Ihle, J.N. (1993) Loss of erythropoietin reponsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene. Proc. Natl Acad. Sci. USA. 90, 6454-6458.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 6454-6458
    • Kreider, B.L.1    Orkin, S.H.2    Ihle, J.N.3
  • 24
    • 0027394585 scopus 로고
    • Genetic evidence that an activation domain of GAL4 does not require acidity and may form a βsheet
    • Leuther, K.K., Salmeron, J.M. and Johnston, S.A. (1993) Genetic evidence that an activation domain of GAL4 does not require acidity and may form a βsheet. Cell, 72, 575-585.
    • (1993) Cell , vol.72 , pp. 575-585
    • Leuther, K.K.1    Salmeron, J.M.2    Johnston, S.A.3
  • 25
    • 0024571802 scopus 로고
    • Transcription activation by the adenovirus Ela protein
    • Lillie, J.W. and Green, M.R. (1989) Transcription activation by the adenovirus Ela protein. Nature, 338, 39-44.
    • (1989) Nature , vol.338 , pp. 39-44
    • Lillie, J.W.1    Green, M.R.2
  • 26
    • 0029034251 scopus 로고
    • ATF-2 contains a phosphorylation-dependent transcriptional activation domain
    • Livingstone, C., Patel, G. and Jones, N. (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J., 14, 1785-1797.
    • (1995) EMBO J. , vol.14 , pp. 1785-1797
    • Livingstone, C.1    Patel, G.2    Jones, N.3
  • 27
    • 0025687550 scopus 로고
    • New light on myc and myb. Part II. myb
    • Luscher, B. and Eisenman, R. (1990) New light on myc and myb. Part II. myb. Genes Dev., 4, 2235-2241.
    • (1990) Genes Dev. , vol.4 , pp. 2235-2241
    • Luscher, B.1    Eisenman, R.2
  • 28
    • 0027297647 scopus 로고
    • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
    • Marais, R., Wynne, J. and Treisman, R. (1993) The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell, 73, 381-393.
    • (1993) Cell , vol.73 , pp. 381-393
    • Marais, R.1    Wynne, J.2    Treisman, R.3
  • 29
    • 0028963735 scopus 로고
    • Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF
    • Merika, M. and Orkin, S.H. (1995) Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF. Mol. Cell. Biol. 15, 2437-2447.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2437-2447
    • Merika, M.1    Orkin, S.H.2
  • 30
    • 0024564101 scopus 로고
    • Steroid hormone receptors compete for factors that mediate their enhancer function
    • Meyer, M.E., Gronemeyer, H., Turcotte, B., Bocquel, M.T., Tasset, D. and Chambon, P. (1989) Steroid hormone receptors compete for factors that mediate their enhancer function. Cell, 57, 433-442.
    • (1989) Cell , vol.57 , pp. 433-442
    • Meyer, M.E.1    Gronemeyer, H.2    Turcotte, B.3    Bocquel, M.T.4    Tasset, D.5    Chambon, P.6
  • 31
    • 0024333776 scopus 로고
    • Selection of lineage-restricted cell lines immortalized at different stages of hematopoietic differentiation from the murine cell line 32D
    • Migliaccio, G., Miglicaccio, A.R., Broudy, V., Kreider, B., Rovera, G. and Adamson, J.W. (1989) Selection of lineage-restricted cell lines immortalized at different stages of hematopoietic differentiation from the murine cell line 32D. J. Cell Biol., 109, 833-841.
    • (1989) J. Cell Biol. , vol.109 , pp. 833-841
    • Migliaccio, G.1    Miglicaccio, A.R.2    Broudy, V.3    Kreider, B.4    Rovera, G.5    Adamson, J.W.6
  • 32
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins
    • Miller, I.J. and Bieker, J.J. (1993) A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol. Cell Biol., 13, 2776-2786.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2776-2786
    • Miller, I.J.1    Bieker, J.J.2
  • 33
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • Mitchell, P.J. and Tjian, R. (1989) Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science, 245, 371-378.
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell, P.J.1    Tjian, R.2
  • 34
    • 0028097870 scopus 로고
    • Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-α on the serum albumin promoter
    • Nerlov, C. and Ziff, E.B. (1994) Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-α on the serum albumin promoter. Genes Dev., 8, 350-362.
    • (1994) Genes Dev. , vol.8 , pp. 350-362
    • Nerlov, C.1    Ziff, E.B.2
  • 35
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez, B., Michalovich, D., Bygrave, A., Ploemacher, R. and Grosveld, F. (1995) Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature, 375, 316-318.
    • (1995) Nature , vol.375 , pp. 316-318
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 36
    • 0025201279 scopus 로고
    • Globin gene regulation and switching: Circa 1990
    • Orkin, S.H. (1990) Globin gene regulation and switching: circa 1990. Cell, 63, 665-672.
    • (1990) Cell , vol.63 , pp. 665-672
    • Orkin, S.H.1
  • 37
    • 0028990264 scopus 로고
    • Lethal β-thalassemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins, A.C. Sharpe, A.H. and Orkin, S.H. (1995) Lethal β-thalassemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature, 375, 318-322.
    • (1995) Nature , vol.375 , pp. 318-322
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 38
    • 0028874393 scopus 로고
    • Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an α helix
    • Petersen, J.M., Skalicky, J.J., Donaldson, L.W., McIntosh, L.P. Alber, T. and Graves, B.J. (1995) Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an α helix. Science, 269, 1866-1869.
    • (1995) Science , vol.269 , pp. 1866-1869
    • Petersen, J.M.1    Skalicky, J.J.2    Donaldson, L.W.3    McIntosh, L.P.4    Alber, T.5    Graves, B.J.6
  • 39
    • 0023683667 scopus 로고
    • How eukaryotic transcriptional activators work
    • Ptashne, M. (1988) How eukaryotic transcriptional activators work. Nature, 335, 683-689.
    • (1988) Nature , vol.335 , pp. 683-689
    • Ptashne, M.1
  • 41
    • 0027521782 scopus 로고
    • Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor
    • Russo, M.W., Matheny, C. and Milbrandt, J. (1993) Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor. Mol. Cell. Biol., 13, 6858-6865.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6858-6865
    • Russo, M.W.1    Matheny, C.2    Milbrandt, J.3
  • 43
    • 0029658844 scopus 로고    scopus 로고
    • Erythroid Krüppel-like Factor (EKLF) exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny
    • Southwood, C.M., Downs, K.M. and Bieker, J.J. (1996) Erythroid Krüppel-like Factor (EKLF) exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny. Dev. Dyn., 206, 248-259.
    • (1996) Dev. Dyn. , vol.206 , pp. 248-259
    • Southwood, C.M.1    Downs, K.M.2    Bieker, J.J.3
  • 44
    • 0025800296 scopus 로고
    • Mechanisms for diversity in gene expression patterns
    • Struhl, K. (1991) Mechanisms for diversity in gene expression patterns. Neuron, 7, 177-181.
    • (1991) Neuron , vol.7 , pp. 177-181
    • Struhl, K.1
  • 45
    • 0027395118 scopus 로고
    • The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, Myeloid Nuclear Factor 1 (MyNF1)
    • Suzow, J. and Friedman, A.D. (1993) The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, Myeloid Nuclear Factor 1 (MyNF1). Mol. Cell. Biol., 13, 2141-2151.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2141-2151
    • Suzow, J.1    Friedman, A.D.2
  • 46
    • 0025786590 scopus 로고
    • Coactivators for a proline-rich activator purified from the multisubnit human TFIID complex
    • Tanese, N., Pugh, B.F. and Tijan, R. (1991) Coactivators for a proline-rich activator purified from the multisubnit human TFIID complex. Genes Dev., 5, 2212-2224.
    • (1991) Genes Dev. , vol.5 , pp. 2212-2224
    • Tanese, N.1    Pugh, B.F.2    Tijan, R.3
  • 47
    • 0028337542 scopus 로고
    • Transcriptional activation: A complex puzzle with few easy pieces
    • Tjian, R. and Maniatis, T. (1994) Transcriptional activation: a complex puzzle with few easy pieces. Cell, 77, 5-8.
    • (1994) Cell , vol.77 , pp. 5-8
    • Tjian, R.1    Maniatis, T.2
  • 48
    • 0025309467 scopus 로고
    • Human globin locus activation region (LAR): Role in temporal control
    • Townes, T.M. and Behringer, R.R. (1990) Human globin locus activation region (LAR): role in temporal control. Trends Genet., 6, 219-223.
    • (1990) Trends Genet. , vol.6 , pp. 219-223
    • Townes, T.M.1    Behringer, R.R.2
  • 49
    • 0029003061 scopus 로고
    • Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
    • Wang, Y. and Prives, C. (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature, 376, 88-91.
    • (1995) Nature , vol.376 , pp. 88-91
    • Wang, Y.1    Prives, C.2
  • 50
    • 0029051646 scopus 로고
    • Transcription complex stability and chromatin dynamics in vivo
    • Wijgerde, M., Grosveld, F. and Fraser, P. (1995) Transcription complex stability and chromatin dynamics in vivo. Nature, 377, 209-213.
    • (1995) Nature , vol.377 , pp. 209-213
    • Wijgerde, M.1    Grosveld, F.2    Fraser, P.3
  • 51
    • 0028097921 scopus 로고
    • The structure and function of proline-rich regions in proteins
    • Williamson, M.P. (1994) The structure and function of proline-rich regions in proteins. Biochem. J., 297, 249-260.
    • (1994) Biochem. J. , vol.297 , pp. 249-260
    • Williamson, M.P.1
  • 52
    • 0013484134 scopus 로고
    • Structural basis for the binding of proline-rich peptides to SH3 domains
    • Yu, H., Chen, J.K., Feng, S., Dalgarno, D.C., Brauer, A.W. and Schreiber, S.L. (1994) Structural basis for the binding of proline-rich peptides to SH3 domains. Cell, 76, 933-945.
    • (1994) Cell , vol.76 , pp. 933-945
    • Yu, H.1    Chen, J.K.2    Feng, S.3    Dalgarno, D.C.4    Brauer, A.W.5    Schreiber, S.L.6


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