Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease

Journal of Neuroscience Research

Volumn 51, Issue 4, 1998, Pages 423-430

  Andjelkovic, Anuska V ^a   Pachter, Joel S ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Cerebral microvasculature; CNS microvascular endothelium; Endothelial dysfunction

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1;

ALLERGIC ENCEPHALOMYELITIS; ALZHEIMER DISEASE; BLOOD BRAIN BARRIER; BRAIN INFECTION; BRAIN MALARIA; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; ENCEPHALITIS; HAEMOPHILUS INFLUENZAE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MENINGOENCEPHALITIS; MICROVASCULATURE; MULTIPLE SCLEROSIS; NONHUMAN; PARKINSON DISEASE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SHORT SURVEY; VASCULAR ENDOTHELIUM;

ANIMALS; BACTERIAL INFECTIONS; BRAIN; ENDOTHELIUM, VASCULAR; HUMANS; INFLAMMATION; MICROCIRCULATION; MULTIPLE SCLEROSIS; NEURODEGENERATIVE DISEASES; VIRUS DISEASES;

EID: 0032519737     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980215)51:4<423::AID-JNR2>3.0.CO;2-E     Document Type: Short Survey

References (88)

1. Abbott NJ, Romero IA (1996) Transporting therapeutics across the blood-brain barrier. Mol Med Today 2:106-113.
2. Archelos JJ, Jung S, Maurer M, Schmied M, Lassman H, Tamatani T, Miyasaka M, Toyka KV, Hartung HP (1993) Inhibition of experimental autoimmune encephalomyelitis by antibody to the intercellular adhesion molecule ICAM-1. Ann Neurol 34:145-154.
3. Benveniste E (1993) Astrocyte-microglia interactions. In Murphy S (ed): "Astrocytes Pharmacology And Function." New York: Academic Press, Inc., pp 355-382.
4. Blumberg BM, Epstein LG, Saito Y, Chen D, Sharer LR, Anand R (1992) Human immunodeficiency virus type I nef quasispecies in pathological tissue. J Virol 66:5256-5264.
5. Brightman MW, Tao-Cheng JH (1993) Tight junctions of brain endothelium and epithelium. In Pardridge WM (ed) "The Blood-Brain Barrier Cellular And Molecular Biology." New York: Raven Press, pp 107-126.
6. Brown EJ (1997) Adhesive interactions in the immune system. Trends Cell Biol 7:289-295.
7. Cancilla P, Bready J, Berliner J (1993) Astrocyte-endothelial cell interactions. In Murphy S (ed) "Astrocytes Pharmacology And Function." New York: Academic Press, Inc., pp 383-397.
8. Cannella B, Raine CS (1995) The adhesion molecule and cytokine profile of multiple sclerosis. Ann Neurol 37:424-435.
9. Chakravarthy U, Stitt AW, McNally J, Bailie JR, Hoey EM, Duprex P (1995) Nitric oxide synthase activity and expression in retinal capillary endothelial cells and pericytes. Current Eye Res 14:285-294.
10. Clapham PR (1997) HIV and chemokines: ligands sharing cell-surface receptors. Trends Cell Biol 7:264-268.
11. Claudio L (1996) Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients. Acta Neuropathol 91:6-14.
12. Claudio L, Raine CS, Brosnan CF (1995) Evidence of persistent blood-brain barrier abnormalities in chronic progressive multiple sclerosis. Acta Neuropathol 90:228-238.
13. Clore GM, Gronenborn AM (1995) Three-dimensional structures of alpha and beta chemokines. FASEB J 9:57-62.
14. Crone C, Olesen SP (1982) Electrical resistance of brain microsvascular endothelium. Brain Res 241:49-55.
15. Dal Pan GJ, McArthur JC, Harrison MJG (1997) Neurological symptoms in human immunodeficiency virus infection. In Berger JR, Levy RM (eds): "AIDS And The Nervous System," 2nd Ed. Lippincott-Raven: Philadelphia, pp 141-172.
16. Davis LE, Hjelle BL, Miller VE, Palmer DL, Llewellyn AL, Merlin TL, Young SA, Mills RG, Wachsman W, Wiley CA (1992) Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 42:1736-1739.
17. Dejana E, Zanetti A, Del Maschio A (1996) Adhesive proteins at endothelial cell-to-cell junctions and leukocyte extravasation. Homeostasis 26:210-219.
18. Dhawan S, Weeks BS, Soderland C, Schnaper HW, Toro LA, Asthana SP, Hewelett IK, Stetler-Stevenson WG, Yamada KM, Meltzer MS (1995) HIV-1 infection alters monocyte interactions with human microvascular endothelial cells. J Immunol 154:422-432.
19. Dickson DW, Lee SC, Hatch W, Mattiace LA, Brosnan CF, Lyman WD (1994) Macrophages and microglia in HIV-related CNS neuropathology. Res Publ Assoc Res Nerv Mental Dis 72:99-118.
20. Dines KC, Powell HC (1997) Mast cell interactions with the nervous system: relationship to mechanisms of disease. J Neuropathol Exp Neurol 56:627-640.
21. Droogan AG, McMillan SA, Douglas JP, Hawkins SA (1996) Serum and cerebrospinal fluid levels of soluble adhesion molecules in multiple sclerosis: predominant intrathecal release of vascular adhesion molecule-1. J Neuroimmunol 64:185-191.
22. Eddleston M, Mucke L (1993) Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 54:15-36.
23. Fabray Z, Fitzsimmons KM, Herlein JA, Moninger TO, Dobbs MB, Hart MN (1993) Production of the cytokines interleukin 1 and 6 by murine brain microvessel endothelium and smooth muscle pericytes. J Neuroimmunol 47:23-34.
24. Gearing AJ, Newman W (1993) Circulating adhesion molecules in disease. Immunol Today 14:506-512.
25. Gilles PN, Lathey JL, Spector SA (1995) Replication of macrophagetropic and T-cell tropic strains of immunodeficiency virus type 1 is augmented by macrophage-endothelial cell contact. J Virol 69:2133-2139.
26. Gordon EJ, Myers KJ, Dougherty JP, Rosen H, Ron Y (1995) Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol 62:153-160.
27. Graeber MB, Streit WJ, Buringer D, Sparks DL, Kreutzberg GW (1992) Ultrastructural location of major histocompatibility complex (MHC) class II positive perivascular cells in histologically normal human brain. J Neuropathol Exp Neurol 51:303-311.
28. Gray F, Hurtel M, Hurtel B (1993) Early central nervous system changes in human in human immunodeficiency virus (HIV)-infection. Neuropathol Appl Neurobiol 19:3-9.
29. Hayashi M, Luo Y, Laning J, Streiter RM, Dorf ME (1995) Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells. J Neuroimmunol 60:143-150.
30. Hirschi KK, D'Amore PA (1996) Pericytes in the microvasculature. Cardiovasc Res 32:687-698.
31. Hogg N, Berlin C (1995) Structure and function of adhesion receptors in leukocyte trafficking. Immunol Today 16:327-330.
32. Howard OMZ, Ben-Baruch A, Oppenheim JJ (1996) Chemokines: progress toward identifying molecular targets for therapeutic agents. Trends Biotech 14:46-51.
33. Horuk R, Martin A, Hesselgesser J, Hadley T, Lu ZH, Wang ZX, Peiper SC (1996) The duffy antigen receptor for chemokines: structural analysis and expression in brain. J Leuk Biol 59:29-38.
34. Huitinga I, Dadmoiseaux JG, Dopp EA, Dijkstra CD (1993) Treatment with anti-CR3 antibodies ED7 and ED8 suppresses experimental allergic encephalomyelitis in Lewis rats. Eur J Immunol 23:709-715.
35. Hulkower K, Brosnan CF, Aquino DA, Cammer W, Kulshrestha S, Guida MP, Rapoport DA, Berman JW (1993) Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis. J Immunol 150: 2525-2533.
36. Jenner P (1994) Oxidative damage in neurodegenerative disease. Lancet 344:796-798.
37. Kalaria RN, Harik SI (1989) Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease. J Neurochem 53:1083-1088.
38. Kalaria RN, Hedera P (1995) Differential degeneration of the cerebral microvasculature in Alzheimer's disease. NeuroReport 6:477-480.
39. Kalaria RN, Pax AB (1992) Increased collagen content of cerebral microvessels in Alzheimer's disease. Brain Res 705:349-352.
40. Kuwai K, Kobayashi Y, Shiratori M, Sobue G, Tamatani T, Miyasaka M, Yodshikai Y (1996) Intrathecal administration of antibodies against LFA-1 and against ICAM-1 suppresses experimental allergic encephalomyelitis in rats. Cell Immunol 171:262-268.
41. Koenig S, Gendelman HE, Orenstein JM, Dal Canto MC, Pezeshpour GH, Yungbluth M, Janotta F, Aksamit A, Martin M, Fauci AS (1986) Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233:1089-1093.
42. Krause D, Kunz J, Dermietzel R (1993) Cerebral pericytes - a second line of defence in controlling blood-brain barrier peptide metabolism. Adv Exp Biol Med 331:149-152.
43. Kreutzberg G (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
44. Kubes P, Granger DN (1996) Leukocyte-endothelial cell interactions evoked by mast cells. Cardiovasc Res 32:699-708.
45. Lal B, Indurti RR, Courard P-O, Goldstein GW, Laterra J (1994) Endothelial cell implantation and survival within experimental gliomas. Proc Natl Acad Sci 91:9695-9699.
46. Lassman H, Zimprich F, Vass K, Hickey WF (1991) Microglial cells are a component of the perivascular glia limitans. J Neurosci Res 28:236-243.
47. Leger OJ, Yednock TA, Tanner L, Horner HC, Hines DK, Keen S, Saldanha J, Jones ST, Fritz LC, Bendig MM (1997) Humanization of a mouse antibody against alpha-4 integrin: a potential therapeutic for the treatment of multiple sclerosis. Human Antibodies 8:3-16.
48. Lou J, Chofflon M, Juillard C, Donati Y, Mili N, Siegrist CA, Grau GE (1997) Brain microvascular endothelial cells and leukocytes derived from patients with multiple sclerosis exhibit increased adhesion capacity. NeuroReport 8:629-633.
49. Mantovani A, Bussolino F, Introna M (1997) Cytokine regulation of endothelial cell function: from molecular level to the bedside. Immunol Today 18:231-240.
50. Marcus BC, Wyble CW, Hynes KL, Gewertz BC (1996) Cytokine-induced increases in endothelial permeability occur after adhesion molecule expression. Surgery 120:411-416.
51. Mato M, Ookawara S, Sakamoto A, Aikawa E, Ogawa T, Mitsuhashi U, Masusawa T, Suzuki H, Honda M, Yazaki Y, Watanabe E, Luoma J, Yla-Herttuala S, Fraser I, Gordon S, Kodama T (1996) Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex. Proc Nail Acad Sci USA 93:3269-3274.
52. McGeer P, Kawamata T, Walker DG, Akiyama H, Tooyama I, McGeer EG (1993) Microglia in degenerative neurological disease. Glai 7:84-92.
53. Miyagishi R, Kikuchi S, Takayama C, Inoue Y, Tashiro K (1997) Identification of cell types producing RANTES. MIP-1 alpha, and MIP-1 beta in rat experimental autoimmune encephalomyelitis by in situ hybridization. J Neuroimmunol 77:17-26.
54. Moor AC, de Vries HE, de Boer AG, Breimer DD (1994) The blood-brain barrier and multiple sclerosis. Biochem. Pharmacol 47:1717-1724.
55. Moses AV, Bloom FE, Pauza CD, Nelson JA (1993) Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactoceramide-independent mechanism. Proc Natl Acad Sci USA 90:10474-10478.
56. Murphy Jr GM, Jia X-C, Song Y, Ong E, Shrivastava R, Bocchini V, Lee YL, Eng LF (1995) Macrophage inflammatory protein-1 α mRNA expression in an immortalized microglial cell line and cortical astrocyte cultures. J Neurosci Res 40:755-763.
57. Murphy PM (1994) The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 12:593-633.
58. Nottet HSLM, Persidsky Y, Sasseville VG, Nukuna AN, Bock P, Zhai QH, Sharer LR, McComb RD, Swindells S, Soderland C, Gendelman HE (1996) Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. J Immunol 156:1284-1295.
59. Nuovo G (1994) In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system. Am J Pathol 144:659-666.
60. Orr EL (1988) Presence and distribution of nervous system-associated mast cells that may modulate experimental autoimmune encephalomyelitis. Ann NY Acad Sci 540:723-726.
61. Pasloske BL, Howard RJ (1994) Malria, the red cell and the endothelium. Annu Rev Med 45:283-295.
62. Patrick D, Betts J, Frey EA, Prameya R, Dorovini-Zis K, Finlay BB (1992) Haemophilus influenzae lipospolysaccharide disrupts confluent monolayers of bovine brain endothelial cells via a serum-dependent cytotoxic pathway. J Infect Dis 165:865-872.
63. Peluso R, Haase A, Stowring L, Edwards M, Ventura P (1985) A Trojan Horse mechanism for the spread of visna virus in monocytes. Virology 147:231-236.
64. Perry VH, Anthony DC, Bolton SJ, Brown HC (1997) The blood-brain barrier and the inflammatory response. Mol Med Today 3:335-341.
65. Persidsky Y, Stins M, Way D, Witte MH, Weinhand M, Kim KS, Bock P, Gendelman HE, Fiala M (1997) A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis. J Immunol 158:3499-3510.
66. Pober JS (1988) Cytokine-mediated activation of vascular endothelium: physiology and pathology. Am J Pathol 133:426-436.
67. Poland SD, Rice GPA, Dekaban GA (1995) HIV-1 infection of human brain-derived microvascular derived endothelial cells in vitro. J Acquir Immuno defic Syndr Hum Retrovirol 8:437-445.
68. Ranshohoff RM, Hamilton TA, Tani M, Stoler MH, Shick HE, Major JA, Estes ML, Thomas DM, Tuohy VK (1993) Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 7:592-600.
69. Resnick L, Berger JR, Shapsak P, Tourtellotte WW (1988) Early penetration of the blood-brain barrier by HIV-1. Neurology 38:9-14.
70. Riedl AG, Watts PM, Edwards RJ, Boobis AR, Jenner P, Marsden CD (1996) Selective localization of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera. Brain Res 743:324-328.
71. Rose LM, Richards TL, Peterson J, Petersen R, Alvord EC Jr (1997) Resolution of CNS lesions following treatment of experimental allergic encephalomyelitis in macaques with monoclonal antibody to the CD18 leukocyte integrin. Multiple Sclerosis 2:259-266.
72. Rutten MJ, Hoover RL, Karnovsky MJ (1987) Electrical resistance and macromolecular permeability of brain endothelial monolayer cultures. Brain Res 425:301-310.
73. Scolding NJ, Zajicek JP, Wood N, Compston DAS (1994) The pathogenesis of demyelinating disease. Prog Neurobiol 43:143-173.
74. Seilhean D, Kobayashi K, He Y, Uchihra T, Rosenblum O, Katlama C, Bricaire F, Duyckaerts C, Hauw JJ (1997) Tumor necrosis factor-alpha, microglia and astrocytes in AIDS dementia complex. Acta Neuropathol 93:508-517.
75. Sein KK, Maeno Y, Thuc HV, Anh TK, Aikawa M (1993) Differential sequestration of parasitized erythrocytes in the cerebrum and cerebellum in human cerebral malaria. Am J Trop Med Hyg 48:504-511.
76. Silver R, Silverman A-J, Vitkovic L, Lederhendler I (1996) Mast cells in the brain: evidence and functional significance. Trends Neurosci 19:25-31.
77. Sims DE (1991) Recent advances in pericyte biology - implications for health and disease. Can J Cardiol 7:431-443.
78. Soilu-Hanninen M, Roytta M, Salmi A, Salonen R (1997) Therapy with antibody against leukocyte integrin VLA-4 (CD49d) is effective and safe in virus-facilitated experimental allergic encephalomyelitis. J Neuroimmunol 72:95-105.
79. Skaper SD, Facci L, Romanello S, Leon A (1996) Mast cell activation causes delayed neurodegeneration in mixed hippocampal cultures via the nitric oxide pathway. J Neurochem 66:1157-1166.
80. Tanaka Y, Adams DH, Shaw S (1993) Regulation of leukocyte recruitment by proadhesive cytokines immobilized on endothelial proteoglycan. Curr Topics Microbiol Immunol 184:99-106.
81. Thomas T, Thomas G, McClendon C, Sutton T, Mullan M (1996) Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature 380:168-171.
82. Tornatore C, Nath A, Amemiya K, Major EO (1991) Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. J Virol 65:6094-6100.
83. Washington R, Burton J, Todd III RF, Newman W, Dragovic L, Dore-Duffy P (1994) Expression of immunologically relevant endothelial activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis. Ann Neurol 35:89-97.
84. 2-integrin avidity by chemoattractants in eosinophils. Proc Natl Acad Sci USA 93:10939-10944.
85. Wiley CA, Achim C (1994) Human immunodeficiency virus is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol 36:36:673-676.
86. Williams A, Van Dam AM, Ritchie D, Eikelenboom P, Fraser H (1997) Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations. Brain Res 754:171-180.
87. Wood PL (1995) Microglia as a unique cellular target in the treatment of stroke: potential neurotoxic mediators produced by activated microglia. Neurolog Res 17:242-247.
88. Zhuang X, Silverman A-J, Silver R (1996) Brain mast cell degranulation regulates blood-brain barrier. J Neurobiol 31:393-403.