The contribution of lipids and lipid metabolism to cellular functions of the Golgi complex

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1404, Issue 1-2, 1998, Pages 85-100

  Fang, Min ^a   Rivas, Marcos P ^a   Bankaitis, Vytas A ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Golgi; Lipid metabolism; Phospholipid transfer protein; Secretion; Signaling

Indexed keywords

LIPID; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN;

CELL FUNCTION; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; LIPID METABOLISM; LIPID TRANSPORT; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; REVIEW; YEAST;

EID: 0032516804     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(98)00049-4     Document Type: Article

References (97)

1. Golgi C. Sur la structure des cellules nerveuses. Arch. Ital. Biol. 30:1898;60-71.
2. Rothman J.E. Mechanisms of intracellular protein transport. Nature. 372:1994;55-63.
3. Rothman J.E., Wieland F.T. Protein sorting by transport vesicles. Science. 272:1996;227-234.
4. Pagano R.E. Lipid traffic in eukaryotic cells: mechanisms for intracellular transport and organelle-specific enrichment of lipids. Curr. Opin. Cell Biol. 2:1990;652-663.
5. Voelker D. Intracellular lipid movement in eukaryotes. Microbiol. Rev. 55:1990;543-560.
6. Moreau P., Cassagne C. Phospholipid trafficking and membrane biogenesis. Biochim. Biophys. Acta. 1197:1994;257-290.
7. Jeckel D., Karrenbauer A., Burger K.N.J., van Meer G., Wieland F. Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions. J. Cell Biol. 117:1992;259-267.
8. Burger K.N.J., van der Bijl P., van Meer G. Topology of sphingolipid galactosyltransferases in endoplasmic reticulum and Golgi: transbilayer movement of monohexosyl sphingolipids is required for higher glycosphingolipid biosynthesis. J. Cell Biol. 133:1996;15-28.
9. Futerman A.H., Stieger B., Hubbard A.L., Pagano R.E. Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J. Biol. Chem. 265:1990;8650-8657.
10. Longmuir K.J. Biosynthesis and distribution of lipids. Curr. Top. Membrane Transp. 29:1987;129-174.
11. Pagano R.E. What is the fate of diacylglycerol produced at the Golgi apparatus? Trends Biochem. Sci. 13:1988;202-205.
12. Jelsema C.L., Morre D.J. Distribution of phospholipid biosynthetic enzymes among cell components of rat liver. J. Biol. Chem. 253:1978;7960-7971.
13. Puoti A., Desponds C., Conzelmann A. Biosynthesis of mannosylinositolphosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi. J. Cell Biol. 113:1991;515-525.
14. Cleves A.E., McGee T.P., Whitters E.A., Champion K.M., Aitken J.R., Dowhan W., Goebl M., Bankaitis V.A. Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell. 64:1991;789-800.
15. McGee T.P., Skinner H.B., Whitters E.A., Henry S.A., Bankaitis V.A. A phosphatidylinositol transfer protein controls the phosphatidylcholine content of yeast Golgi membranes. J. Cell Biol. 124:1994;273-287.
16. Leber A., Hrastnik C., Daum G. Phospholipid synthesizing enzymes in Golgi membranes of the yeast Saccharomyces cerevisiae. FEBS Lett. 377:1995;271-274.
17. van Meer G. Lipids of the Golgi membrane. Trends Cell Biol. 8:1998;29-33.
18. Wattenberg B.W. Glycolipid and glycoprotein transport through the Golgi complex are similar biochemically and kinetically. Reconstitution of glycolipid transport in a cell-free system. J. Cell Biol. 111:1990;421-428.
19. van Echten G., Sandhoff K. Modulation of ganglioside biosynthesis in primary cultured neurons. J. Neurochem. 52:1989;207-214.
20. Pagano R.E., Martin O.C., Kang H.C., Haugland R.P. A novel fluorescent ceramide analogue for studying membrane trafficking in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor. J. Cell Biol. 113:1991;1267-1279.
21. van Meer G., Stetzer E.H.K., Wijnaendts-van-Resandt W., Simons K. Sorting of sphingolipids in epithelial (Madine Darby canine kidney) cells. J. Cell Biol. 105:1987;1623-1635.
22. Orci L., Brown M.S., Goldstein J.L., Garcia-Segura L.M., Anderson R.G.W. Increase in membrane cholesterol: a possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells. Cell. 36:1984;835-845.
23. Simons K., van Meer G. Lipid sorting in epithelial cells. Biochemistry. 27:1988;6197-6202.
24. Brown D., Rose J. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the cell surface. Cell. 68:1992;533-544.
25. Simons K., Ikonen E. Functional rafts in cell membranes. Nature. 387:1997;569-572.
26. van Helvoort A., Smith A.J., Sprong H., Fritzsche I., Schinkel A.H., Borst P., van Meer G. MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocated phosphatidylcholine. Cell. 87:1996;507-518.
27. Wirtz K.W.A. Phospholipid transfer proteins. Annu. Rev. Biochem. 60:1991;73-99.
28. Cleves A.E., McGee T.P., Bankaitis V.A. Phospholipid transfer proteins: a biological debut. Trends Cell Biol. 1:1991;30-34.
29. Alb J.G. Jr., Gedvilaite A., Cartee R.T., Skinner H.B., Bankaitis V.A. Mutant rat phosphatidylinositol/phosphatidylcholine transfer proteins specifically defective in phosphatidylinositol transfer: implications for the regulation of phosphatidylinositol transfer activity. Proc. Natl. Acad. Sci. USA. 92:1995;8826-8830.
30. Dickeson S.K., Lim C.N., Schuyler G.T., Dalton T.P., Helmkamp G.M. Jr., Yarbrough L.R. Isolation and sequence of cDNA clones encoding rat phosphatidylinositol transfer protein. J. Biol. Chem. 264:1989;16557-16564.
31. Bankaitis V.A., Malehorn D.E., Emr S.D., Greene R. The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J. Cell Biol. 108:1989;1271-1281.
32. Bankaitis V.A., Aitken J.R., Cleves A.E., Dowhan W. An essential role for a phospholipid transfer protein in yeast Golgi function. Nature. 347:1990;561-562.
33. Salama S.R., Cleves A.E., Malehorn D.E., Whitters E.A., Bankaitis V.A. Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae. J. Bacteriol. 172:1990;4510-4521.
34. Carmen-Lopez M., Nicaud J.-M., Skinner H.B., Vergnolle C., Kader J.C., Bankaitis V.A., Gaillardin C. A phosphatidylinositol/phosphatidylcholine transfer protein is required for differentiation of the dimorphic yeast Yarrowia lipolytica from the yeast to the mycelial form. J. Cell Biol. 124:1994;113-127.
35. Novick P., Field C., Schekman R. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell. 21:1980;205-215.
36. Rambourg A., Clermont Y., Nicaud J.-M., Gaillardin C., Kepes F. Transformations of membrane-bound organelles in sec14 mutants of the yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. Anat. Rec. 245:1996;447-458.
37. Cleves A.E., Novick P.J., Bankaitis V.A. Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function. J. Cell Biol. 109:1989;2939-2950.
38. Alb J.G. Jr., Kearns M.A., Bankaitis V.A. Phospholipid metabolism and membrane dynamics. Curr. Opin. Cell Biol. 8:1996;534-541.
39. Kearns B.G., McGee T.P., Mayinger P., Gedvilaite A., Phillips S.E., Kagiwada S., Bankaitis V.A. An essential role for diacylglycerol in protein transport from the yeast Golgi complex. Nature. 387:1997;101-105.
40. De Matteis M.A., Sanbini G., Kahn R.A., DiTullio G., Luini A. Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex. Nature. 364:1993;818-821.
41. Simon J.P., Ivanov I.E., Adesnik M., Sabatini D.D. The production of post-Golgi vesicles requires a protein kinase C-like module, but not its phosphorylating activity. J. Cell Biol. 135:1996;355-370.
42. Skinner H.B., McGee T.P., McMaster C.R., Fry M.R., Bell R.M., Bankaitis V.A. Phosphatidylinositol transfer protein stimulates yeast Golgi function by inhibiting choline-phosphate cytidylyltransferase activity. Proc. Natl. Acad. Sci. USA. 92:1995;112-116.
43. Kagiwada S., Kearns B.G., McGee T.P., Fang M., Hosaka K., Bankaitis V.A. The yeast BSD2-1 mutation influences both the requirement for phosphatidylinositol transfer protein function and derepression of phospholipid biosynthetic gene expression in yeast. Genetics. 143:1996;685-697.
44. 2+-activated secretion. Nature. 366:1993;572-575.
45. Cunningham E., Siow K.T., Swigart P., Hsuan J., Bankaitis V., Cockroft S. The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells. Proc. Natl. Acad. Sci. USA. 93:1996;6589-6593.
46. Sha B., Phillips S.E., Bankaitis V.A., Luo M. Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol transfer protein. Nature. 391:1998;506-509.
47. Ganong B.R., Bell R.M. Transmembrane movement of phosphatidylglycerol and diacylglycerol sulfhydryl analogues. Biochemistry. 23:1984;4977-4988.
48. Fang M., Gedvilaite A., Kearns B.G., Kagiwada S., Kearns M., Fung M.K.Y., Bankaitis V.A. Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J. 15:1996;101-113.
49. Hokin L.E. receptors and phosphoinositide-generated second messengers. Annu. Rev. Biochem. 54:1985;205.
50. Eberhard D.A., Cooper C.L., Low M.G., Holz R.W. Evidence that inositol phospholipids are required for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP. Biochem. J. 268:1990;15-25.
51. De Camilli P., Emr S.D., McPherson P.S., Novick P. Phosphoinositides as regulators of membrane traffic. Science. 271:1996;1533-1539.
52. Tanaka S., Hosaka K. Cloning of a cDNA encoding a second phosphatidylinositol transfer protein from rat brain by complementation of the yeast sec14 mutation. J. Biochem. 115:1994;981-984.
53. Westerman J., de Vries K.J., Somerharju P., Timmermans-Hereijgers J.L.P.M., Snoek G.T., Wirtz K.W.A. A sphingomyelin-transferring protein from chicken liver. J. Biol. Chem. 270:1995;14263-14266.
54. Ohashi M., de Vries K.J., Frank R., Snoek G., Bankaitis V., Wirtz K., Huttner W.B. A role for phosphatidylinositol transfer protein in secretory vesicle formation. Nature. 374:1995;173-177.
55. Skinner H.B., Alb J.G. Jr., Whitters E.A., Helmkamp G.M. Jr., Bankaitis V.A. Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product. EMBO J. 12:1993;4775-4784.
56. 2+-activated secretion. Nature. 374:1995;173-177.
57. 2+-activated exocytosis. J. Biol. Chem. 272:1997;19637-19640.
58. 2. Curr. Biol. 5:1995;775-783.
59. Monaco M.E., Gershengorn M.C. Subcellular organization of receptor-mediated phosphoinositide turnover. Endocr. Rev. 13:1992;707-718.
60. Currie R.A., Macleod B.M.G., Downes P.C. The lipid transfer activity of phosphatidylinositol transfer protein is sufficient to account for enhanced phospholipase C activity in turkey erythrocyte ghosts. Curr. Biol. 7:1997;184-190.
61. Hara S., Swigart P., Jones D., Cockroft S. The first five amino acids of the carboxyl terminus of phosphatidylinositol transfer protein (PITP) α play a critical role in inositol lipid signaling. J. Biol. Chem. 272:1997;14908-14913.
62. Panaretou C., Domin J., Cockroft S., Waterfield M.D. Characterization of p150, an adapter protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150-PtdIns 3-kinase complex. J. Biol. Chem. 272:1997;2477-2485.
63. de Vries K.J., Westerman J., Bastiaens P.I.H., Jovin T.M., Wirtz K.W.A., Snoek G.T. Fluorescently labeled phosphatidylinositol transfer protein isoforms (α and β), microinjected into fetal bovine heart endothelial cells, are targeted to distinct intracellular sites. Exp. Cell Res. 227:1996;33-39.
64. Milligan S.C., Alb J.G. Jr., Elagina R.B., Bankaitis V.A., Hyde D.R. The phosphatidylinositol transfer protein domain of Drosophila retinal degeneration B protein is essential for photoreceptor cell survival and recovery from light stimulation. J. Cell Biol. 139:1997;351-363.
65. Hamilton B.A., Smith D.J., Mueller K.L., Kerrebrock A.W., Bronson R.T., van Berkel V., Daly M.J., Krugylak L., Reeve M.P., Nemhauser J.L., Hawkins T.L., Rubin E.M., Lander E.S. The vibrator mutation causes neurodegeneration via reduced expression of PITPα: positional complementation cloning and extragenic suppression. Neuron. 18:1997;711-722.
66. Paris S., Beraud-Dufour S., Robineau S., Bigay J., Antonny B., Chabre M., Chardin P. Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno. J. Biol. Chem. 272:1997;22221-22226.
67. Ktistakis N.T., Brown H.A., Waters M.G., Sternweis P.C., Roth M.G. Evidence that phospholipase D mediates ADP-ribosylation factor-dependent formation of coated vesicles. J. Cell Biol. 134:1996;295-306.
68. Brown H.A., Gutowski S., Moomaw C.R., Slaughter C., Sternweis P.C. ADP-ribosylation factor (ARF), a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell. 75:1993;1137-1144.
69. Cockroft S., Thomas G.M.H., Fensome A., Blandine G., Cunningham E., Gout I., Hiles I., Totty N.F., Truong O., Hsuan J.J. Phospholipase D: a downstream effector of ARF in granulocytes. Science. 263:1994;523-526.
70. Jenkins G.H., Fisette P.L., Anderson R.A. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269:1994;11547-11555.
71. Liscovitch M., Chalifa V., Pertile P., Chen C.-S., Cantley L.C. Novel function of phosphatidylinositol-4,5-bisphosphate as a cofactor for brain membrane phospholipase D. J. Biol. Chem. 269:1994;21403-21406.
72. Poon P.P., Wang X., Rotman M., Huber I., Cukierman E., Cassel D., Singer R.A., Johnston G.C. Saccharomyces cerevisiae Gcs1 is an ADP-ribosylation factor GTPase activating protein. Proc. Natl. Acad. Sci. USA. 93:1996;10074-10077.
73. Hammonds-Odie L.P., Jackson T.R., Profit A.A., Blader I.J., Turck C.R., Prestwich G.D., Theibert A.B. Identification and cloning of centaurin α J. Biol. Chem. 271:1996;18859-18868.
74. Bi K., Roth M.G., Ktistakis N.T. Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex. Curr. Biol. 7:1997;301-307.
75. Antonny B., Hubert I., Paris S., Chabre M., Cassel D. Activation of ADP-ribosylation factor 1 GTPase activating protein by phosphatidylcholine-derived diacylglycerols. J. Biol. Chem. 272:1997;30848-30851.
76. Liscovitch M., Cantley L.C. Signal transduction and membrane traffic: the PITP/phosphoinositide connection. Cell. 81:1995;659-661.
77. Patton-Vogt J.L., Griac P., Sreenivas A., Bruno V., Dowd S., Swede M.J., Henry S.A. Role of the yeast phosphatidylinositol/phosphatidylcholine transfer protein (Sec14p) in phosphatidylcholine turnover and INO1 regulation. J. Biol. Chem. 272:1997;20873-20883.
78. Morris A.J., Engebrecht J., Frohman M.A. Structure and regulation of phospholipase D. Trends Pharmacol. Sci. 17:1996;182-185.
79. Stearns T., Kahn R.A., Botstein D., Hoyt M.A. ADP-ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes. Mol. Cell. Biol. 10:1990;6690-6699.
80. Stearns T., Willingham M.C., Botstein D., Kahn R.A. ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc. Natl. Acad. Sci. USA. 87:1990;1238-1242.
81. Rudge S.A., Morris A.J., Engebrecht J. Relocalization of phospholipase D mediates membrane formation during meiosis. J. Cell Biol. 140:1998;81-90.
82. Schekman R., Orci L. Coat proteins and vesicle budding. Science. 271:1996;1526-1533.
83. Schu P.V., Takegawa K., Fry M.J., Stack J.H., Waterfield M.D., Emr S.D. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene is essential for protein sorting. Science. 260:1993;88-91.
84. Stack J.H., DeWald D.B., Takegawa K., Emr S.D. Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J. Cell Biol. 129:1995;321-334.
85. Stack J.H., Herman P.K., Schu P.V., Emr S.D. A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI3-kinase is essential for protein sorting to the yeast lysosome like vacuole. EMBO J. 12:1993;2195-2204.
86. Sheetz M., Singer S. Biological membranes as bilayer couples. A molecular mechanism for drug-erythrocyte interactions. Proc. Natl. Acad. Sci. USA. 71:1974;4457-4461.
87. Dove S.K., Cooke F.T., Douglas M.R., Sayers L.G., Parker P.J., Michell R.H. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature. 390:1977;187-192.
88. Yamamoto A., DeWald D.B., Boronenkov I.V., Anderson R.A., Emr S.D., Koshland D. Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol. Cell. Biol. 6:1995;525-539.
89. Volinia S., Dhand R., Vanhaesebroeck B., MacDougall L.K., Stein R., Zvelebil M.J., Domin J., Panaretou C., Waterfield M.D. A human phosphatidylinositol 3-kinase complex related to the yeast VPS34-VPS15 protein sorting system. EMBO J. 14:1995;3339-3348.
90. Brown W.J., DeWald D.B., Emr S.D., Plutner H., Balch W.E. Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130:1995;781-796.
91. Jones S.M., Crosby J.R., Salamero J., Howell K.E. A cytosolic complex of p62 and rab6 associates with TGN38/41 and is involved in budding of ascocytic vesicles from the trans-Golgi network. J. Cell Biol. 122:1993;775-788.
92. Jones S.M., Howell K.E. Phosphatidylinositol 3-kinase is required for formation of constitutive transport vesicles from the TGN. J. Cell Biol. 139:1997;339-349.
93. McPherson P.S., Garcia E.P., Slepnev V.I., David C., Zhang X., Grabs D., Sossin W.S., Bauerfind R., Nemoto Y., De Camilli P. A presynaptic inositol 5-phosphatase. Nature. 379:1996;353-357.
94. Suchy S.F., Olivos-Glander I.M., Nussbaum R.L. Lowe syndrome, a deficiency of phosphatidylinositol-4,5-bisphosphate 5-phosphatase in the Golgi apparatus. Hum. Mol. Genet. 4:1995;2245-2250.
95. Whitters E.A., Cleves A.E., McGee T.P., Skinner H.B., Bankaitis V.A. SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J. Cell Biol. 122:1993;79-94.
96. Maceyka M., Machamer C.E. Ceramide accumulation uncovers a recycling pathway for the cis-Golgi network marker, infectious bronchitis virus M protein. J. Cell Biol. 139:1997;1411-1418.
97. Cluett E.B., Kuismanen E., Machamer C.A. Heterogeneous distribution of the unusual phospholipid semilysobisphosphatidic acid through the Golgi complex. Mol. Biol. Cell. 8:1997;2233-2240.