Discriminative stimulus properties of the 5-HT(1A) receptor agonist BAY x 3702 in the rat

European Journal of Pharmacology

Volumn 357, Issue 1, 1998, Pages 1-8

  De Vry, Jean ^a   Jentzsch, Klaus Rüdiger ^a  

^a CNS Research   (Germany)

Author keywords

5 HT(1A) receptor; Animal model; BAY x 3702; Discriminative stimulus; Drug discrimination; Rat

Indexed keywords

4 PHOSPHONOMETHYLPIPECOLIC ACID; APTIGANEL; CALCIUM CHANNEL STIMULATING AGENT; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR; ELTOPRAZINE; FLESINOXAN; IDAZOXAN; IPSAPIRONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NIMODIPINE; PINDOLOL; PRAZOSIN; RACLOPRIDE; REPINOTAN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; BENZOPYRANS; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; MALE; PIPERAZINES; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; REGRESSION ANALYSIS; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; THIAZOLES; TIME FACTORS;

EID: 0032508739     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00503-2     Document Type: Article

References (34)

1. 2 agonists in rats. Pharmacol. Toxicol. 64:1989;165-172.
2. 1A receptors. Eur. J. Pharmacol. 253:1994;139-147.
3. De Beun R., Lohmann A., Schneider R., De Vry J. Ethanol intake reducing effects of ipsapirone in rats are not due to simple stimulus substitution. Pharmacol. Biochem. Behav. 53:1996;891-898.
4. De Beun R., Lohmann A., Kuhl E., Dalmus M., Schreiber R., De Vry J. Stimulus properties of the L-type calcium channel agonist BAY k 8644 in rats. Behav. Pharmacol. 7:1996;346-354.
5. 1A receptor agonists: recent developments and controversial issues. Psychopharmacology. 121:1995;1-26.
6. De Vry J., Traber J. Discriminative stimulus properties of the noncompetitive NMDA antagonist MK-801 in the rat. Soc. Neurosci. Abstr. 15:1989;1166.
7. 1A receptors in anxiety. In: Briley, M., File, S.E. (Eds.), New Concepts in Anxiety. MacMillan, London, pp. 94-129.
8. 1A receptor activity. Behav. Pharmacol. 3:1992;S53.
9. De Vry J., Schreiber R., de Beun R. Stimulus properties of (-)-BAY k 8644, a calcium channel agonist: comparison with the calcium channel antagonist nimodipine in rats. Behav. Pharmacol. 7:1996;29.
10. De Vry J., Dietrich H., Glaser T., Heine H.-G., Horvàth E., Jork R., Maertins T., Mauler F., Opitz W., Scherling D., Schohe-Loop R., Schwarz T. BAY x 3702. Drugs Future. 22:1997;341-349.
11. 1A receptor agonist. J. Pharmacol. Exp. Ther. 284:1998;1082-1094.
12. 1A receptor antagonist WAY-100635. Eur. J. Pharmacol. 281:1995;81-88.
13. 1A agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT). Pharmacol. Biochem. Behav. 25:1986;135-139.
14. Gommans J., Hijzen T.H., Maes R.A., Mos J., Olivier B. Discriminative stimulus properties of flesinoxan: effects of enantiomers, (S)-UH301 and WAY-100635. Eur. J. Pharmacol. 284:1995;135-140.
15. Hoffmeister F., Benz U., Heise A., Krause H.P., Neuser V. Behavioral effects of nimodipine in animals. Arzneimittelforschung/Drug Res. 32:1982;347-360.
16. 1A receptor agonist BAY x 3702 in the rat model of acute subdural hematoma. J. Neurotrauma. 14:1997;800.
17. 1A receptor agonist BAY x 3702 in a rat model of permanent focal cerebral ischemia and traumatic brain injury. Soc. Neurosci. Abstr. 23:1997;1923.
18. Kleven M.S., Koek W. Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino)tetralin in pigeons and rats: species similarities and differences. J. Pharmacol. Exp. Ther. 284:1998;238-249.
19. Lehmann J., Chapman A.G., Meldrum B.S., Hutchison A., Tsai C., Wood P.L. CGS 19755 is a potent and competitive antagonist at the NMDA-type receptors. Eur. J. Pharmacol. 154:1988;89-93.
20. McBurney R.N., Reddy N.L., Hamilton P.N., Taylor E.M., Cotter R.E., Fischer J.B., Goldin S.M., Keana J.F.W., Wolcott T.J., Kirk C.J. Neuroprotective efficacy of CNS 1102, a novel noncompetitive NMDA antagonist. J. Cereb. Blood Flow Metab. 11:1991;S219.
21. 1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids. Psychopharmacology. 122:1995;336-345.
22. 1A receptor agonist flesinoxan in pigeons. Eur. J. Pharmacol. 325:1997;145-153.
23. Rabin R.A., Winter J.C. Studies on the biochemical basis for the discriminative properties of 8-hydroxy-2-(di-n-propylamino)tetralin. Eur. J. Pharmacol. 235:1993;237-243.
24. 1A receptor ligands by means of in vivo animal models. Eur. J. Pharmacol. 315:1996;245-254.
25. 1A receptors. Psychopharmacology. 108:1992;85-92.
26. Schipper J., Tulp M.T.M., Berkelmans B., Mos J., Van der Heijden J.A.M., Oliver B. Preclinical pharmacology of flesinoxan: a potential anxiolytic and antidepressant drug. Human Psychopharmacology. 6:1991;S53-61.
27. 1A receptor agonists in the rat. J. Pharmacol. Exp. Ther. 265:1993;572-579.
28. 1A receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin. J. Pharmacol. Exp. Ther. 275:1995;822-831.
29. 1A neuroprotectant BAY x 3702 in the rat. Soc. Neurosci. Abstr. 23:1997;1923.
30. Traber J., Davies M.A., Dompert W.U., Glaser T., Schuurman T., Seidel P.-R. Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain Res. Bull. 12:1984;741-744.
31. Winter J.C. Generalization of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and ipsapirone to yohimbine. Pharmacol. Biochem. Behav. 29:1988;193-195.
32. 1A receptor ligands by drug discrimination. Eur. J. Pharmacol. 333:1997;113-122.
33. Wong E.H.F., Kemp J.A., Priestly T., Knight A.R., Woodruff G.N., Iversen L.L. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc. Natl. Acad. Sci. USA. 83:1986;7104-7108.
34. Ybema C.E., Slangen J.L., Olivier B., Mos J. Dose-dependent discriminative stimulus properties of 8-OH-DPAT. Behav. Pharmacol. 4:1993;610-624.